中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

51 records (took 0.028 seconds)

    Integrated security network
    11.
    发明授权
    Integrated security network 有权

    公开(公告)号：US10002507B2

    公开(公告)日：2018-06-19

    申请号：US15229055

    申请日：2016-08-04

    Applicant: David Stuart Wilson ,  Andrew Wilson

    Inventor： David Stuart Wilson ,  Andrew Wilson

    IPC: G08B13/196 ,  G08B25/00 ,  G08B25/14 ,  H04L9/00 ,  G08B29/04

    CPC classification number: G08B13/19656 ,  G08B13/19665 ,  G08B25/002 ,  G08B25/14 ,  G08B29/046 ,  H04L9/00 ,  H04L9/0819

    Abstract: A security system architecture and method of operation that combines a local security network with control panel and sensors, a central monitoring station (CMS), and a separate operator computer server that provides a web portal for both the homeowner and CMS, that maintains a persistent connection between the control panel and CMS allowing failsafe dual-path signaling. This dual-path signaling technique is extended to provide an effective “smash and grab alarm”, and various approaches to dual-path signal management are disclosed including handshaking, persistent domain monitoring, relayed Operator 3-to-CMS signaling, etc. Improved processes for remotely accessing video are also disclosed along with an improved process for remote control panel configuration, and control panel interfacing with home automation appliances.

    DETECTION OF BACTERIA AND FUNGI
    12.
    发明申请
    DETECTION OF BACTERIA AND FUNGI 有权
    检测细菌和真菌

    公开(公告)号：US20120107865A1

    公开(公告)日：2012-05-03

    申请号：US13264177

    申请日：2010-04-19

    Applicant: Stuart Wilson ,  William Mullen

    Inventor： Stuart Wilson ,  William Mullen

    IPC: C12Q1/25

    CPC classification number: C12Q1/04 ,  C12Q1/68 ,  C12Q1/689 ,  C12Q1/6895 ,  C12Q2521/501 ,  C12Q2527/119 ,  C12Q2533/10 ,  C12Q2537/149 ,  G01N2333/9015

    Abstract: A method of detecting a ligase expressing micro-organism in a sample comprises steps of treating the sample under conditions that inhibit the activity of ATP-dependent ligase from mammalian cells but which do not inhibit the activity of the microbial ligases, contacting the sample or a portion of the sample with a nucleic acid molecule which acts as a substrate for ligase activity in the sample, incubating the thus contacted sample under conditions suitable for ligase activity; and specifically determining the presence and/or the amount of a ligated nucleic acid molecule resulting from the action of the ligase on the substrate nucleic acid molecule to indicate the presence of the ligase expressing micro-organism. The micro-organism may be a fungus or a bacterium or both. High pH conditions may be employed to inactivate mammalian ligases. Related kits are described.

    Abstract translation: 检测样品中连接酶表达微生物的方法包括以下步骤：在抑制ATP依赖性连接酶从哺乳动物细胞的活性但不抑制微生物连接酶的活性，接触样品或 样品的一部分与核酸分子起作用，作为样品中连接酶活性的底物，在适合连接酶活性的条件下孵育由此接触的样品; 并且具体地确定由连接酶对底物核酸分子的作用产生的连接的核酸分子的存在和/或量，以指示表达微生物的连接酶的存在。 微生物可以是真菌或细菌或两者。 可以使用高pH条件来灭活哺乳动物连接酶。 描述相关工具包。

    Methods for Detection of Micro-Organisms
    13.
    发明申请
    Methods for Detection of Micro-Organisms 审中-公开
    微生物检测方法

    公开(公告)号：US20100291564A1

    公开(公告)日：2010-11-18

    申请号：US12667818

    申请日：2008-07-09

    Applicant: Christopher John Stanley ,  Stuart Wilson

    Inventor： Christopher John Stanley ,  Stuart Wilson

    IPC: C12Q1/68 ,  C12N9/48

    CPC classification number: C12Q1/04 ,  C12N9/93 ,  C12Q1/02 ,  C12Q1/18 ,  C12Q1/25 ,  C12Q1/689 ,  G01N2333/9015 ,  C12Q2565/301 ,  C12Q2521/501

    Abstract: NAD-dependent ligase is identified as an indicator of micro-organisms in a sample. A method of detecting the presence of an NAD-dependent ligase expressing micro-organism in a sample comprises the steps of: (a) contacting the sample with a nucleic acid molecule which acts as a substrate for NAD-dependent ligase activity in the sample, (b) incubating the thus contacted sample under conditions suitable for NAD-dependent ligase activity; and (c) specifically determining the presence of a ligated nucleic acid molecule resulting from the action of the NAD-dependent ligase on the substrate nucleic acid molecule to indicate the presence of the NAD-dependent ligase expressing micro-organism. The method has a number of applications and kits for carrying out the methods are also provided. Lysostaphin preparations substantially free from nuclease and/or ligase contaminants are produced by heating a lysostaphin preparation which contains nuclease and/or ligase contaminants under conditions whereby nuclease and/or ligase activity is reduced whereas endopeptidase activity of the lysostaphin is substantially unaffected.

    Abstract translation: NAD依赖性连接酶被鉴定为样品中微生物的指标。 检测样品中NAD依赖性连接酶表达微生物的存在的方法包括以下步骤：（a）使样品与作为样品中NAD依赖性连接酶活性的底物的核酸分子接触， （b）在适合于NAD依赖性连接酶活性的条件下孵育由此接触的样品; 和（c）特异性地确定由NAD依赖性连接酶在底物核酸分子上的作用产生的连接的核酸分子的存在，以指示表达微生物的NAD依赖性连接酶的存在。 该方法还提供了许多用于执行方法的应用和套件。 通过在其中核酸酶和/或连接酶活性降低的条件下加热含有核酸酶和/或连接酶污染物的溶葡萄球菌素制剂而产生基本上不含核酸酶和/或连接酶污染物的溶葡萄球菌素制剂，而溶葡萄球菌素的内肽酶活性基本上不受影响。

    PURINE DERIVATIVES
    14.
    发明申请
    PURINE DERIVATIVES 审中-公开
    嘌呤衍生物

    公开(公告)号：US20090270427A1

    公开(公告)日：2009-10-29

    申请号：US12433388

    申请日：2009-04-30

    Applicant: Peter Martin FISHER ,  Michael JARMAN ,  Edward MCDONALD ,  Bernard NUTLEY ,  Florence RAYNAUD ,  Stuart WILSON ,  Paul WORKMAN

    Inventor： Peter Martin FISHER ,  Michael JARMAN ,  Edward MCDONALD ,  Bernard NUTLEY ,  Florence RAYNAUD ,  Stuart WILSON ,  Paul WORKMAN

    IPC: A61K31/52 ,  C07D473/16 ,  A61P35/00 ,  C12N9/99

    CPC classification number: C07D473/16

    Abstract: The present invention relates to compounds of formula 1 or pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is methyl, ethyl or isopropyl, and the other is H; R3 and R4 are each independently H, branched or unbranched C1-C6 alkyl, or aryl, and wherein at least one of R3 and R4 is other than H; R5 is a branched or unbranched C1-C5 alkyl group or a C1-C6 cycloalkyl group, each of which may be optionally substituted with one or more OH groups; R6, R7, R8 and R9 are each independently H, halogen, NO2, OH, OMe, CN, NH2, COOH, CONH2, or SO2NH2. A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula 1, and the use of said compounds in treating proliferative disorders, viral disorders, CNS disorders, diabetes, stroke, alopecia or neurodegenerative disorders.

    Abstract translation: 本发明涉及式1化合物或其药学上可接受的盐，其中R 1和R 2之一是甲基，乙基或异丙基，另一个是H; R 3和R 4各自独立地为H，支链或非支链的C 1 -C 6烷基或芳基，并且其中R 3和R 4中的至少一个不是H; R5是支链或非支链C 1 -C 5烷基或C 1 -C 6环烷基，其各自可以任选被一个或多个OH基取代; R6，R7，R8和R9各自独立地为H，卤素，NO2，OH，OMe，CN，NH2，COOH，CONH2或SO2NH2。 本发明的另一方面涉及包含式1化合物的药物组合物，以及所述化合物在治疗增殖性疾病，病毒性疾病，中枢神经系统疾病，糖尿病，中风，脱发或神经变性疾病中的用途。

    Wall lining method and system
    15.
    发明授权
    Wall lining method and system 失效
    墙衬法和系统

    公开(公告)号：US07029204B1

    公开(公告)日：2006-04-18

    申请号：US10129479

    申请日：2000-11-03

    Applicant: Geoffrey Leigh Webber ,  Kevin Stuart Wilson ,  Ian Tupling ,  Andrew George Hornung ,  Robert Garratt

    Inventor： Geoffrey Leigh Webber ,  Kevin Stuart Wilson ,  Ian Tupling ,  Andrew George Hornung ,  Robert Garratt

    IPC: E21B20/02 ,  E02D17/20

    CPC classification number: E02D29/0233 ,  E02D5/74

    Abstract: A method of lining a wall face comprises assembling a wall of concrete panels (16) close to the face to be lined, attaching the panels to the face to be lined by ground anchorages (12) pretensioned to provide the required resistance to hydrostatic pressure, the anchorages being grouted into the face at one end, and anchored to the respective panel at the other end, and filling the void between the wall and the face with free-draining material (14). The invention also relates to a system of lining a wall face using concrete panels and ground anchorages. Preferably the panels are cast in molds and have a synthetic low permeability sheet (29) incorporated into one or both sides of the panel during the casting process.

    Abstract translation: 一种衬在墙面上的方法包括将混凝土板（16）的壁组装在靠近待衬里的表面上，将板连接到由预紧的地面锚固件（12）衬里的面上，以提供所需的静水压力， 锚固件在一端被灌浆到面中，并在另一端锚固到相应的板，并且用自由排水材料（14）填充壁和面之间的空隙。 本发明还涉及使用混凝土面板和地面锚固件来衬砌壁面的系统。 优选地，板在模具中铸造并且在铸造过程中具有合并到板的一侧或两侧的合成低渗透性片（29）。

    Third-stage turbine bucket airfoil
    18.
    发明授权
    Third-stage turbine bucket airfoil 失效
    第三级涡轮机叶翼

    公开(公告)号：US06474948B1

    公开(公告)日：2002-11-05

    申请号：US09886406

    申请日：2001-06-22

    Applicant: Peter Paul Pirolla ,  Gunnar Leif Siden ,  David John Humanchuk ,  Steven Robert Brassfield ,  Paul Stuart Wilson

    Inventor： Peter Paul Pirolla ,  Gunnar Leif Siden ,  David John Humanchuk ,  Steven Robert Brassfield ,  Paul Stuart Wilson

    IPC: F01D514

    CPC classification number: F01D5/141 ,  F05D2240/301 ,  Y10S416/02 ,  Y10S416/05

    Abstract: The third-stage buckets have airfoil profiles substantially in accordance with Cartesian coordinate values of X, Y and Z set forth in inches in Table I wherein Z is a perpendicular distance from a plane normal to a radius of the turbine centerline and containing the X and Y values with the Z value commencing at zero in the X, Y plane at the radially innermost aerodynamic section of the airfoil and X and Y are coordinates defining the airfoil profile at each distance Z. The X, Y and Z values may be scaled as a function of the same constant or number to provide a scaled-up or scaled-down airfoil section for the bucket.

    Abstract translation: 第三级铲斗具有基本上符合表I中以英寸表示的X，Y和Z的笛卡尔坐标值的翼型，其中Z是垂直于涡轮机中心线半径的平面的垂直距离，并且包含X和 Y值在Z轴的X，Y平面上在X轴和Y轴的径向最内空气动力学部分处开始为零，X和Y是在每个距离Z处定义翼型轮廓的坐标.X，Y和Z值可以被缩放为 相同的常数或数字的功能来提供用于铲斗的放大或缩小的翼型部分。

    Integrated security network
    20.
    发明授权
    Integrated security network 有权

    公开(公告)号：US11508224B2

    公开(公告)日：2022-11-22

    申请号：US16371928

    申请日：2019-04-01

    Applicant: David Stuart Wilson ,  Andrew Wilson

    Inventor： David Stuart Wilson ,  Andrew Wilson

    IPC: G08B13/196 ,  G08B25/00 ,  G08B25/14 ,  H04L9/00 ,  G08B29/04 ,  H04L9/08

    Abstract: A security system architecture and method of operation that combines a local security network with control panel and sensors, a central monitoring station (CMS), and a separate operator computer server that provides a web portal for both the homeowner and CMS, that maintains a persistent connection between the control panel and CMS allowing failsafe dual-path signaling. This dual-path signaling technique is extended to provide an effective “smash and grab alarm”, and various approaches to dual-path signal management are disclosed including handshaking, persistent domain monitoring, relayed Operator 3-to-CMS signaling, etc. Improved processes for remotely accessing video are also disclosed along with an improved process for remote control panel configuration, and control panel interfacing with home automation appliances.

Patent Agency Ranking