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公开(公告)号：US20050016287A1
公开(公告)日：2005-01-27
申请号：US10920861
申请日：2004-08-18
CPC分类号： G01L7/022 , A61M16/044 , A61M2016/0027 , G01L7/041 , G01L7/043 , G01L7/063
摘要： An apparatus is provided for indicating the presence of pressure within a collection chamber of a device such as a chest drainage device. The apparatus includes a bladder configured to be positioned within the collection chamber or within another chamber in fluid flow communication with the collection chamber. The bladder has a concavity formed therein and configured to contract or expand in response to pressure in the collection chamber. The apparatus also includes surfaces associated with the bladder that are configured to move with respect to one another upon contraction or expansion of the concavity of the bladder, thereby indicating pressure within the collection chamber.
摘要翻译： 提供一种用于指示在例如胸部引流装置的装置的收集室内存在压力的装置。 该装置包括被配置为定位在收集室内或在与收集室流体流动连通的另一个室内的囊。 气囊具有形成在其中的凹部，并且构造成响应于收集室中的压力而收缩或膨胀。 该装置还包括与膀胱相关联的表面，其被构造成在囊的凹部收缩或膨胀时相对于彼此移动，从而指示收集室内的压力。
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公开(公告)号：US06783554B2
公开(公告)日：2004-08-31
申请号：US09789333
申请日：2001-02-20
IPC分类号： A61F202
CPC分类号： D04B1/22 , A61B17/12022 , A61B17/12099 , A61B17/12168 , A61B17/12177 , A61F2/0063 , A61F2250/0023 , D04B1/02 , D04B21/02 , D04B21/10 , D10B2509/08
摘要： A method and apparatus relating to a biocompatible soft tissue implant is disclosed. The implant, in the form of a prosthesis, is constructed of a knitted pile mesh material arranged into either a 3-dimensional structure or a planar shape or structure. The material or fabric includes a plurality of filament extensions projecting outwardly therefrom. The filament extensions can be radially projecting looping filaments from one or more rows of the knitted pile mesh material. The combination of the filament extensions with the 3-dimensional structure results in the biocompatible implant having a structural resistance to hinder anticipated crushing forces applied to the implant, and also provide a suitable 3-dimensional structure for promoting rapid tissue in-growth to anchor such implant without migration and strengthen the repaired tissue area.
摘要翻译： 公开了一种与生物相容性软组织植入相关的方法和装置。 以假体形式的植入物由布置成3维结构或平面形状或结构的针织绒头网状材料构成。 材料或织物包括从其向外突出的多个细丝延伸部。 丝线延伸部可以是一排或多排针织绒网材料的径向突出的细丝。 长丝延伸与三维结构的组合导致生物相容性植入物具有阻碍施加到植入物的预期破碎力的结构阻力，并且还提供合适的三维结构，用于促进快速组织生长以锚定 植入物没有迁移，并加强了修复的组织区域。
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13.发明授权公开(公告)号：US06774155B2
公开(公告)日：2004-08-10
申请号：US10196692
申请日：2002-07-16
IPC分类号： C08F248
CPC分类号： C08J7/123 , A61F2/06 , A61F2250/0023
摘要： The invention is directed to methods for fabricating devices from polymer precursors, along with devices so fabricated. The methods of the invention include the steps of plasma treating a polymer based resin, paste, preform billet, or extrudate, and employing the treated polymer in the fabricated device. According to one embodiment, the fabricated device can include implantable prosthetics such as heart valves, sutures, vascular access devices, vascular grafts, shunts, catheters, single layered membranes, double layered membranes, and the like. Devices fabricated according to one embodiment of the invention include regions having selected porosity, permeability and/or chemistry characteristics.
摘要翻译： 本发明涉及从聚合物前体制造器件的方法以及如此制造的器件。 本发明的方法包括以下步骤：等离子体处理聚合物基树脂，糊料，预成型坯坯或挤出物，并在制造的装置中使用经处理的聚合物。 根据一个实施例，制造的装置可以包括可植入假肢，例如心脏瓣膜，缝线，血管通路装置，血管移植物，分流器，导管，单层膜，双层膜等。 根据本发明的一个实施方案制造的装置包括具有选择的孔隙率，渗透性和/或化学特性的区域。
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公开(公告)号：US06573311B1
公开(公告)日：2003-06-03
申请号：US09400813
申请日：1999-09-22
IPC分类号： C08F248
CPC分类号： C08J7/123 , A61F2/06 , A61F2250/0023
摘要： The invention is directed to methods for fabricating devices from polymer precursors, along with devices so fabricated. The methods of the invention include the steps of plasma treating a polymer based resin, paste, preform billet, or extrudate, and employing the treated polymer in the fabricated device. According to one embodiment, the fabricated device can include implantable prosthetics such as heart valves, sutures, vascular access devices, vascular grafts, shunts, catheters, single layered membranes, double layered membranes, and the like. Devices fabricated according to one embodiment of the invention include regions having selected porosity, permeability and/or chemistry characteristics.
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公开(公告)号：US06423089B1
公开(公告)日：2002-07-23
申请号：US09296349
申请日：1999-04-22
IPC分类号： A61F206
摘要： A vascular endoprosthesis is formed of a tubular liner preform with a continuous surface and having a diameter smaller than that of an intended vessel. The liner is inserted to a treatment site, and its sheet material undergoes a radially-directed expansion to a final size that fits the vessel. Insertion and in situ expansion are achieved using a catheter assembly in which either an internal stent, such as a stiff-filament helically woven tube, or an inflatable balloon urge the liner preform outwardly against the inner wall of the vessel. The stent, or one or more simple internal snap-rings anchor the expanded liner in place. The expanded liner is porous, or becomes more porous during expansion, and one or more aspects of its porosity are tailored to the intended treatment goal of immobilizing treatment material, isolating cells, or permitting controlled permeation of selected materials.
摘要翻译： 血管内假体由具有连续表面并且直径小于预期血管的直径的管状衬垫预制件形成。 将衬垫插入到处理部位，并且其片材经历径向膨胀至适合容器的最终尺寸。 使用导管组件实现插入和原位扩张，其中内部支架例如刚性丝状螺旋编织管或可膨胀气囊将衬垫预制件向外压靠在容器的内壁上。 支架或一个或多个简单的内部卡环将扩张的衬垫固定就位。 膨胀的衬垫是多孔的，或在膨胀期间变得更多孔，并且其孔隙率的一个或多个方面是针对固定化处理材料，分离细胞或允许所选材料的受控渗透的预期治疗目标。
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公开(公告)号：US06287337B1
公开(公告)日：2001-09-11
申请号：US09246312
申请日：1999-02-08
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/06 , A61F2/105 , A61F2/2412 , A61F2/88 , A61F2002/072 , A61F2240/001 , A61L27/16 , A61L27/34 , A61L27/507 , C08L27/18
摘要： A porous tube suitable for use as a vascular graft prosthesis and a method of making it is disclosed. It has a structure of porous polytetrafluoroethylene having a fibrous structure of nodes and fibers connecting the nodes together and an integrated intrawall circumferential support adjacent to areas of variable porosity. This invention provides a polytetrafluoroethylene polymer in a porous form useful as artificial internal organs for, for example vascular bypass, vascular access, and endovascular prosthesis. PTFE walls are found with radial zones of differing porosity are described.
摘要翻译： 公开了适合用作血管移植假体的多孔管及其制造方法。 它具有多孔聚四氟乙烯的结构，其具有连接节点的节点和纤维的纤维结构，以及与可变孔隙度区域相邻的整体的内部周向支撑。 本发明提供一种多孔形式的聚四氟乙烯聚合物，其用作例如血管旁路，血管通路和血管内假体的人造内脏。 发现PTFE壁具有不同孔隙率的径向区域。
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公开(公告)号：US5807358A
公开(公告)日：1998-09-15
申请号：US472144
申请日：1995-06-07
申请人： Steve A. Herweck , Theodore Karwoski , David Cross
发明人： Steve A. Herweck , Theodore Karwoski , David Cross
CPC分类号： A61M1/3627 , A61M1/0013 , A61M1/0031 , A61M1/0033
摘要： A blood collection device has a modular suction regulator assembly in the form of an adjustable negative pressure relief valve which controls the level of suction in a collection chamber by admitting air to a short bleed-in passage proximate to a suction connection. The modular assembly is a canister which drops into a receptacle oriented transversely in the collection vessel, and defines a laterally-directed intake manifold which resists blockage. The intake passes centrally through the canister along a path spanned by a filter, past a hat-shaped poppet supported on a compression spring. Fluted and threaded members control the scale and range of poppet response so that the assembly may be calibrated before installation. A face plate covers the installed canister, and radial vanes in the intake manifold double as gripping elements for manual adjustment of the assembly. A bellows meter provides refined suction resolution by linearly advancing across an oblique or curved reference line. Other improvements include a compact and balanced layout of suction canister, seal chamber and collection chamber, and a rigid handle assembly having five faces integral with the device.
摘要翻译： 血液采集装置具有可调式负压释放阀形式的模块式抽吸调节器组件，其通过将空气接近靠近抽吸连接处的短的通入通道来控制收集室中的抽吸水平。 模块化组件是一种罐，该罐可以放入收集容器中横向定向的容器中，并限定一个防止阻塞的横向定向的进气歧管。 进气口沿着由过滤器跨过的路径中心穿过罐体，经过支撑在压缩弹簧上的帽形提升阀。 槽形和螺纹构件控制提升阀响应的尺寸和范围，以便在安装之前校准组件。 面板覆盖安装的罐，并且进气歧管中的径向叶片作为用于手动调节组件的夹紧元件加倍。 波纹管表通过线性前进穿过斜线或弯曲参考线提供精确的吸力分辨率。 其他改进包括吸盘，密封腔和收集室的紧凑平衡的布局，以及具有与该装置一体的五个面的刚性手柄组件。
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公开(公告)号：US5722964A
公开(公告)日：1998-03-03
申请号：US487468
申请日：1995-06-07
CPC分类号： A61M1/0013 , A61M1/0031 , A61M1/0033 , A61M1/3627
摘要： A blood collection vessel includes a blood inlet, a pooling region in which blood from the inlet collects, and an outlet in the pooling region for reinfusion of the collected blood. A filter located in the blood path between inlet and outlet extends at least in part into the pooling region and impounds clots so they remain away from the outlet but suspended in the collected blood. Preferably, the filter is located to provide venting between both sides of the filter. In one embodiment the filter is a vertical wall, which defines a shielded outlet column or chimney extending above the outlet. Blood permeates to the outlet region over a broad area, and the column forms an open suction path that prevents suction differentials from arising across the filter, so clots cannot be sucked through the large-pore material. With the clots residing in the collected fluid, the total fluid loss is directly displayed in a single window at all times, and maximal use is made of the limited volume in the vessel. In another embodiment, the filter constitutes a false floor or basket in the pooling region. A preferred construction employs filter material on a support grid, to form a flexible and self-supporting filter sheet, which inserts like a plate to compartmentalize the collection vessel and form an impounding surface in the pooling region.
摘要翻译： 血液采集容器包括血液入口，来自入口的血液收集的汇集区域以及汇集区域中用于回收血液回输的出口。 位于入口和出口之间的血液路径中的过滤器至少部分地延伸到汇集区域中并扣留凝块，使得它们保持远离出口但悬浮在收集的血液中。 优选地，过滤器被定位成在过滤器的两侧之间提供排气。 在一个实施例中，过滤器是垂直壁，其限定在出口上方延伸的屏蔽出口塔或烟囱。 血液在大面积上渗透到出口区域，柱形成一个开放的吸入路径，防止吸入差异跨越过滤器，因此凝块不能通过大孔材料吸入。 在收集的液体中存在凝块的情况下，总的流体损失始终直接显示在单个窗口中，并且最大限度地利用了容器中有限的体积。 在另一个实施例中，过滤器构成汇集区域中的假地板或篮子。 优选的结构是在支撑格栅上使用过滤材料，以形成柔性和自支撑的过滤片，其将类似板的插入物分隔成收集容器并在汇集区域中形成蓄水表面。
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19.发明授权
公开(公告)号：US5474824A
公开(公告)日：1995-12-12
申请号：US268240
申请日：1994-06-29
IPC分类号： A61F2/06 , A61L27/16 , A61L27/56 , B29C47/00 , B29C55/00 , B29C69/00 , B29D23/00 , B29K27/12 , B29K105/04 , D02J1/06
CPC分类号： B29D23/001 , A61F2/06 , A61L27/16 , A61L27/56 , B01D67/0027 , B01D69/02 , B01D69/12 , B01D71/36 , B29C47/0004 , B29C47/0021 , B29C55/005 , B01D2325/02 , B29C47/0023 , B29C47/0026 , B29C47/0042 , B29C47/0057 , B29C47/062 , B29C47/065 , B29K2027/18 , B29K2105/04 , B29L2023/005 , B29L2023/007 , Y10T428/139 , Y10T428/1397 , Y10T428/24273 , Y10T428/249986 , Y10T428/24999 , Y10T428/249992 , Y10T428/31544
摘要： A process for producing a shaped porous article includes the steps of providing an extrudate of a fluoropolymer material which is capable of being stretched and bilaterally stretching the extrudate along a longitudinal axis. The stretching step is carried out under conditions sufficient to yield an article which is substantially uniformly stretched over a major portion of its length. After stretching, the material has a unique through-pore microstructure characterized by elongate nodes connected by fibrils. The stretched material is sintered while being maintained in its stretched state to produce the shaped porous article. A significant feature of the inventive process is that stretching is carried out by displacing both ends of the extruded material as opposed to known method wherein only one end of an extruded material is stretched, resulting in a microporous fluoropolymer article which are different than conventional fluoropolymer stretching/expansion processes.
摘要翻译： 一种生产成形多孔制品的方法包括以下步骤：提供含氟聚合物材料的挤出物，该挤出物能够沿着纵向轴线被拉伸和双向拉伸挤出物。 拉伸步骤在足以产生在其长度的主要部分上基本上均匀拉伸的制品的条件下进行。 拉伸后，该材料具有独特的通孔微结构，其特征在于由原纤维连接的细长节点。 拉伸的材料在保持拉伸状态下被烧结以产生成形的多孔制品。 本发明方法的一个重要特征是通过使挤出材料的两端位移来进行拉伸，与已知方法相反，其中仅挤出材料的一端被拉伸，得到与常规含氟聚合物拉伸不同的微孔含氟聚合物制品 /扩展过程。
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公开(公告)号：US5141504A
公开(公告)日：1992-08-25
申请号：US385823
申请日：1989-07-26
IPC分类号： A61M1/00
CPC分类号： A61M1/0013 , A61M1/0056 , A61M2205/3348 , A61M2205/59
摘要： A drainage device includes a vessel having a plurality of sub-chambers one of which is a regulated drainage collection chamber, and two of which cooperate to maintain a selected suction level in the drainage collection chamber. A stopcock proximate to the vessel communicates directly with the two cooperating sub-chambers, and allows quick adjustment and stable operation in varying environments. A float ball arrangement provides an indication of water loss that may compromise the water seal. The device is suitable for wound drainage, and may be used as a cardiotomy reservoir or a thoracic cavity drain device. Different embodiments collect blood for autologous infusion.
摘要翻译： 排水装置包括具有多个子室的容器，其中一个是受调节的排水收集室，其中两个辅助以在排液收集室中保持选定的吸入水平。 靠近船舶的旋塞阀与两个协作的子舱直接通信，并且允许在不同的环境中进行快速调节和稳定的操作。 浮球布置提供可能损害水封的失水指示。 该装置适用于伤口引流，可用作心脏切开术储存器或胸腔排液装置。 不同的实施例收集用于自体输注的血液。
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