公开(公告)号：US20240131473A1

公开(公告)日：2024-04-25

申请号：US18547489

申请日：2022-02-23

Applicant: VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY

Inventor： Spencer MARSH ,  Kevin J. PRIDHAM ,  Linda Jane JOURDAN ,  Robert G. GOURDIE

IPC: B01D61/14

CPC classification number: B01D61/14 ,  B01D2311/2676 ,  B01D2315/10 ,  B01D2315/16

Abstract: Described in certain example embodiments herein are methods of isolating exosomes from a biological fluid, such as those containing caseins.

公开(公告)号：US20230220018A1

公开(公告)日：2023-07-13

申请号：US17927082

申请日：2021-05-22

Applicant: VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY ,  VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.

Inventor： Glenda Gillaspy ,  Catherine Freed ,  Sarah Phoebe Williams ,  Zhiwu Wang

IPC: C07K14/415 ,  C07K14/39 ,  C12N15/82

CPC classification number: C07K14/415 ,  C07K14/39 ,  C12N15/8261

Abstract: Described herein are engineered cells and plants that contain a heterologous Diadenosine and Diphosphoinositol Polyphosphate Phosphohydrolase (DDP1) polypeptide, a heterologous DDP1 encoding polynucleotide, a vector or vector system comprising a heterologous DDP1 encoding polynucleotide, or a combination thereof. Also described herein are methods of making and using the engineered cells and plants described herein.

公开(公告)号：US20220074770A1

公开(公告)日：2022-03-10

申请号：US17017194

申请日：2020-09-10

Applicant: VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY

Inventor： Vasileios KYRITSIS ,  Kevin Todd LOWE ,  Maurice BRISTOW ,  Peter LOFTUS

IPC: G01F1/66

Abstract: A flow machine having a flow passage and an air flow measurement system comprising a plurality of acoustic sensors. The acoustic sensors comprise at least one acoustic transmitter configured to transmit an acoustic waveform through the airflow passing through the flow passage to an acoustic receiver. At least one of the acoustic sensors is rotatable relative to one or more other acoustic sensor.

公开(公告)号：US20210290539A1

公开(公告)日：2021-09-23

申请号：US17264793

申请日：2019-07-30

Applicant: Robert G. GOURDIE ,  VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. ,  VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY

Inventor： Robert G. GOURDIE ,  L. JANE JOURDAN ,  Eda ROGERS

IPC: A61K9/127 ,  C07K14/705 ,  A61K47/46 ,  A61K9/00 ,  A61P17/02 ,  A61P9/06 ,  A61P25/00 ,  A61P27/02 ,  A23C9/152

Abstract: Described herein are engineered hemichannels, engineered vesicles that can contain the one or more of the engineered hemichannels, pharmaceutical formulations thereof, and uses thereof. In some aspects, the engineered vesicles can include one or more cargo molecules. Also described herein are methods of loading the engineered vesicles. In some aspects, loading of one or more cargo molecules engineered vesicles can be optionally via an engineered hemichannel contained in the engineered vesicle.

公开(公告)号：US20190315919A1

公开(公告)日：2019-10-17

申请号：US16340739

申请日：2017-10-10

Applicant: SOLVAY SPECIALTY POLYMERS ITALY S.p.A. ,  VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY

Inventor： Kelly D. BRANHAM ,  David B. ROLLER ,  Stéphane JEOL ,  Marco APOSTOLO ,  Robert B. MOORE ,  Lindsey ANDERSON ,  Samantha TALLEY ,  Yuan XIJING

IPC: C08G65/48 ,  C08G65/40

Abstract: Described here are blocky PEEK copolymers and corresponding synthesis methods. It was surprisingly found that synthesis of blocky PEEK copolymers in a non-solvent environment with respect to PEEK produced blocky PEEK copolymers with high degrees of functionalization and crystallinity. The blocky PEEK copolymers had an increased blocky structure, relative to corresponding PEEK copolymer synthesized with other known methods. Moreover, membranes formed from the blocky PEEK polymers are particularly desirable in fuel cell applications. For example, the membranes formed from the blocky PEEK polymers had surprisingly large ion conductivities as well as significantly improved chemical and thermal resistance, at least in part, to the improved functionalization and crystallinity.

公开(公告)号：US20180107931A1

公开(公告)日：2018-04-19

申请号：US15842403

申请日：2017-12-14

Applicant: Virginia Polytechnic Institute and State University

Inventor： Christopher L. Barrett ,  Madhav V. Marathe ,  Keith R. Bisset

IPC: G06N5/02 ,  G06Q30/00 ,  G06F17/00 ,  G06Q10/00

CPC classification number: G06N5/022 ,  G06F17/00 ,  G06N5/02 ,  G06Q10/00 ,  G06Q30/00

Abstract: Systems, methods, and computer-readable media for generating a data set are provided. One method includes generating a data set based on input data using a plurality of brokers. The method further includes receiving a request from a user and determining whether the request can be fulfilled using data currently in the data set. When the request can be fulfilled using data currently in the data set, the data is accessed using broker(s) configured to provide access to data within the data set. When the request cannot be fulfilled using data currently in the data set, at least one new broker is spawned using existing broker(s) and additional data needed to fulfill the request is added to the data set using the new broker. The method further includes generating a response to the request using one or more of the plurality of brokers.

公开(公告)号：US09870531B2

公开(公告)日：2018-01-16

申请号：US15156934

申请日：2016-05-17

Applicant: Virginia Polytechnic Institute and State University

Inventor： Christopher L. Barrett ,  Madhav V. Marathe ,  Keith R. Bisset

IPC: G06F17/00 ,  G06N5/02 ,  G06Q10/00 ,  G06Q30/00

CPC classification number: G06N5/022 ,  G06F17/00 ,  G06N5/02 ,  G06Q10/00 ,  G06Q30/00

Abstract: Systems, methods, and computer-readable media for generating a data set are provided. One method includes generating a data set based on input data using a plurality of brokers. The method further includes receiving a request from a user and determining whether the request can be fulfilled using data currently in the data set. When the request can be fulfilled using data currently in the data set, the data is accessed using broker(s) configured to provide access to data within the data set. When the request cannot be fulfilled using data currently in the data set, at least one new broker is spawned using existing broker(s) and additional data needed to fulfill the request is added to the data set using the new broker. The method further includes generating a response to the request using one or more of the plurality of brokers.

公开(公告)号：US20170344438A1

公开(公告)日：2017-11-30

申请号：US15596876

申请日：2017-05-16

Applicant: Virginia Polytechnic Institute and State University

Inventor： Yuce Bilgiday ,  Nahid Farhady Ghalaty ,  Patrick R. Schaumont

IPC: G06F11/14 ,  G06F21/71

Abstract: Aspects disclosed in the detailed description include a microprocessor fault detection and response system. The microprocessor fault detection and response system utilizes a hardware-based fault-attack aware microprocessor extension (FAME) and a software-based trap handler for detecting and responding to a fault injection on a microprocessor. Upon detecting the fault injection, the hardware FAME switches the microprocessor from a normal mode to a safe mode and instructs the microprocessor to invoke the software-based trap handler in the safe mode. The hardware-based FAME provides fault recovery information to the software-based trap handler via a fault recovery register (FRR) for restoring the microprocessor to a fault-free state. By utilizing a combination of the hardware-based FAME and the software-based trap handler, it is possible to effectively protect the microprocessor from malicious fault attacks without significantly increasing performance and area overheads.

公开(公告)号：US20250007021A1

公开(公告)日：2025-01-02

申请号：US18215191

申请日：2023-06-28

Applicant: Microvast, Inc. ,  Virginia Polytechnic Institute and State University

Inventor： Jinsuo ZHANG ,  Mingyang ZHANG ,  Yun XU ,  Bryan Yonemoto ,  Wenjuan Liu Mattis

IPC: H01M10/54 ,  C22B1/00 ,  C22B3/26 ,  C22B26/12 ,  C22B26/20

Abstract: The main purpose of the invention is to provide a method for recovery of cathode materials, cathode materials and electric vehicles. The method for recovery of cathode materials comprises the following steps: step 1, adding cathode materials and a metal reducing agent (MRA) to a molten salt (MS), the cathode materials and the MRA performing a reduction reaction in MS to obtain precipitates and MS solutions. By using the method for recovery of cathode materials of the present invention, main metal elements in cathode materials of a secondary battery are effectively recovered, and compared with pyrometallurgical or hydrometallurgical methods in the prior art, the recovery rate of a metal mixture can reach unexpected 90% or more. Furthermore, the method of the present invention is environmentally friendly, all raw materials can be recycled and reused and no exhaust gases or waste liquids contaminating the environment are discharged.

公开(公告)号：US11999097B2

公开(公告)日：2024-06-04

申请号：US17057568

申请日：2019-05-21

Applicant: VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY

Inventor： Ryan Hensleigh ,  Xiaoyu Zheng

IPC: B29C64/124 ,  B29C64/30 ,  B29K105/00 ,  B33Y10/00 ,  B33Y40/20 ,  B33Y70/00

CPC classification number: B29C64/124 ,  B29C64/30 ,  B33Y10/00 ,  B33Y40/20 ,  B33Y70/00 ,  B29K2105/0014

Abstract: Described herein are electroless material deposition methods and techniques that can be used to deposit one or more materials on a structure in a selective manner such that deposition can occur in predetermined areas. The methods and techniques of selective electroless material deposition methods described herein can be used to selectively deposit material(s) on 3D printed structures. In some aspects, the 3D structures can contain micro-features that can have one or more materials selectively deposited on their surface in one or more locations.