公开(公告)号：US20240117370A1

公开(公告)日：2024-04-11

申请号：US18517109

申请日：2023-11-22

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Marcos Fernando de GODOY LUSSO ,  James A. STRICKLAND ,  Jesse FREDERICK ,  Dongmei XU ,  Chengalrayan KUDITHIPUDI

IPC: C12N15/82 ,  A24B13/00

CPC classification number: C12N15/8225 ,  A24B13/00 ,  C12N15/8218 ,  C12N15/8243 ,  C12N15/8261

Abstract: The present disclosure includes methods and compositions for improving leaf quality in low-alkaloid tobacco plants, e.g., by combining inducible promoters and non-coding RNAs for suppression of an ornithine decarboxylase (ODC) gene. Also provided are low alkaloid tobacco plants with normal, suppressed, or otherwise altered polyamine levels. Further provided are tobacco plants with altered total alkaloid, nicotine levels, commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.

公开(公告)号：US20240018534A1

公开(公告)日：2024-01-18

申请号：US18450522

申请日：2023-08-16

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Chengalrayan KUDITHIPUDI ,  Jaemo YANG ,  Yanxin SHEN ,  Dongmei XU ,  Ujwala WAREK ,  James Strickland ,  Jesse FREDERICK

IPC: C12N15/82

CPC classification number: C12N15/8205 ,  C12N15/8229

Abstract: The present disclosure provides the identification of promoters that are preferentially active in tobacco axillary buds. Also provided are tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing tobacco plants comprising reduced or no sucker growth.

公开(公告)号：US20230247961A1

公开(公告)日：2023-08-10

申请号：US17892461

申请日：2022-08-22

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Jesse FREDERICK ,  Yanxin SHEN ,  Dongmei XU ,  Ujwala WAREK ,  James Arthur STRICKLAND

IPC: A01H6/82 ,  C07K14/415 ,  C12N15/82 ,  A01H5/12 ,  A01H1/02 ,  A01H1/06 ,  A24B15/20 ,  C12Q1/6895 ,  G01N33/00

CPC classification number: A01H6/823 ,  C07K14/415 ,  C12N15/8243 ,  A01H5/12 ,  A01H1/02 ,  A01H1/06 ,  A24B15/20 ,  C12Q1/6895 ,  G01N33/0098 ,  C12Q2600/13 ,  C12Q2600/156 ,  C12Q2600/16

Abstract: This disclosure provides a number of sequences involved in the transport of alkaloids from the root to the leaf in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences, and tobacco products made from such plants.

公开(公告)号：US20220010324A1

公开(公告)日：2022-01-13

申请号：US17337161

申请日：2021-06-02

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Sreepriya PRAMOD ,  Marcos Fernando de GODOY LUSSO ,  Jesse FREDERICK ,  Andrew ADAMS ,  Dongmei XU

IPC: C12N15/82

Abstract: The present disclosure provides tobacco having genetic modification(s) in a group of ERF genes. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.

公开(公告)号：US20210230627A1

公开(公告)日：2021-07-29

申请号：US17150704

申请日：2021-01-15

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Jesse FREDERICK ,  Andrew Carl ADAMS ,  Dongmei XU

IPC: C12N15/82

Abstract: The present disclosure provides products, compositions, and methods for improving nitrogen use efficiency in tobacco plants, including e.g., Burley tobacco. This disclosure further provides genetic markers for tracking enhanced nitrogen use efficiency phenotypes in tobacco plants and for introgressing enhanced nitrogen use efficiency phenotypes into tobacco plants. The disclosure also provides tobacco plants comprising enhanced nitrogen use efficiency and methods to the creation of tobacco plants comprising enhanced nitrogen use efficiency.

公开(公告)号：US20230035750A1

公开(公告)日：2023-02-02

申请号：US17406829

申请日：2021-08-19

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Dongmei XU ,  Jesse FREDERICK ,  Chengalrayan KUDITHIPUDI ,  Yanxin SHEN ,  James STRICKLAND ,  Jaemo YANG

IPC: C12N15/82

Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.

公开(公告)号：US20220204981A1

公开(公告)日：2022-06-30

申请号：US17571138

申请日：2022-01-07

Applicant: Altria Client Services LLC

Inventor： Marcos Fernando de GODOY LUSSO ,  James A. STRICKLAND ,  Jesse FREDERICK ,  Dongmei XU ,  Chengalrayan KUDITHIPUDI

IPC: C12N15/82 ,  A24B13/00

Abstract: The present disclosure includes methods and compositions for improving leaf quality in low-alkaloid tobacco plants, e.g., by combining inducible promoters and non-coding RNAs for suppression of an ornithine decarboxylase (ODC) gene. Also provided are low alkaloid tobacco plants with normal, suppressed, or otherwise altered polyamine levels. Further provided are tobacco plants with altered total alkaloid, nicotine levels, commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.

公开(公告)号：US20200318129A1

公开(公告)日：2020-10-08

申请号：US16908891

申请日：2020-06-23

Applicant: Altria Client Services LLC

Inventor： Dongmei XU ,  Chengalrayan KUDITHIPUDI ,  Yanxin SHEN ,  Jaemo YANG ,  Jesse FREDERICK ,  James STRICKLAND

IPC: C12N15/82 ,  C07K14/415 ,  A24B13/00 ,  A24B15/10

Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.

公开(公告)号：US20200032283A1

公开(公告)日：2020-01-30

申请号：US16589783

申请日：2019-10-01

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Chengalrayan KUDITHIPUDI ,  Yanxin SHEN ,  Dongmei XU ,  Jesse FREDERICK ,  Jaemo YANG

IPC: C12N15/82 ,  C07K14/415

Abstract: This disclosure provides a number of sequences involved in axillary bud growth in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences or transgenes of such sequences, and tobacco products made from tobacco leaf harvested from such plants.

公开(公告)号：US20190271000A1

公开(公告)日：2019-09-05

申请号：US16291878

申请日：2019-03-04

Applicant: Altria Client Services LLC

Inventor： Marcos Fernando de GODOY LUSSO ,  James A STRICKLAND ,  Jesse FREDERICK ,  Dongmei XU ,  Chengalrayan KUDITHIPUDI

IPC: C12N15/82

Abstract: The present disclosure includes methods and compositions for improving leaf quality in low-alkaloid tobacco plants, e.g., by combining inducible promoters and non-coding RNAs for suppression of an ornithine decarboxylase (ODC) gene. Also provided are low alkaloid tobacco plants with normal, suppressed, or otherwise altered polyamine levels. Further provided are tobacco plants with altered total alkaloid, nicotine levels, commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.