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公开(公告)号：US20250032726A1
公开(公告)日：2025-01-30
申请号：US18917164
申请日：2024-10-16
Applicant: AMGEN INC.
Inventor： Jakob Halkjaer Pedersen , Matias Melander
Abstract: A drug delivery device includes a housing defining a shell having a proximal end and a distal end and a longitudinal axis extending between the proximal end and the distal end, a needle assembly at least partially disposed within the housing at the proximal end, a drive assembly at least partially disposed within the housing and operably coupled to the needle assembly, and an audible indicator operably coupled to the drive assembly. The needle assembly includes a syringe containing a medicament and a needle or a cannula. The drive assembly is movable between an initial position and a second position that results in the medicament being expelled from the syringe. Upon the drive assembly being positioned in the second position, the audible indicator engages the drive assembly to generate an audible sound indicating the medicament has been expelled from the syringe.
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公开(公告)号：US20240390585A1
公开(公告)日：2024-11-28
申请号：US18696167
申请日：2022-10-05
Applicant: AMGEN INC.
Inventor： Emil Gram Spork , Matias Melander , Alexandre Gegelashvili , Yangkun Song , Thomas Peter Sonderby
Abstract: A drug delivery device includes a housing having proximal and distal ends and a longitudinal axis extending therebetween, an injection assembly at least partially disposed within the housing including a needle or a cannula, a drive assembly operably coupled with the injection assembly, a shield slidably coupled with the housing and operably coupled with the drive assembly, and a retention mechanism. The drive assembly is engageable to deliver a medicament via the injection assembly. The shield is positionable in an extended position in which at least a proximal end extends a distance beyond the proximal end of the housing and a retracted position where the proximal end of the housing protrudes a distance beyond the proximal end of the shield. Moving the shield to the retracted position engages the drive assembly to deliver the medicament via the injection assembly. The retention mechanism limits movement of the drive assembly to restrict engagement thereof such that the drive assembly is restricted from delivering the medicament via the injection assembly.
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公开(公告)号：US20240238529A1
公开(公告)日：2024-07-18
申请号：US18409480
申请日：2024-01-10
Applicant: AMGEN INC.
Inventor： Adam B. McCullough , Ronald Forster , Joseph Michael Iglesias , Matias Melander , Rasmus Øhlenschlæger , Christian Plambech , Lars Stenholt , Bjarke Lykke Ludvig Svendsen
CPC classification number: A61M5/3145 , A61M5/20 , A61M5/31583 , A61M2005/3143
Abstract: An injector includes a housing having a syringe assembly and an actuating mechanism at least partially disposed within the housing. The syringe assembly includes a syringe barrel that stores a medicament to be injected into a user, a needle assembly, and a filter member disposed adjacent to the needle assembly. The actuating mechanism is operatively coupled to the syringe assembly and includes a torque spring that exerts a torque to urge the medicament through the filter member to be injected into the user. The actuating mechanism further includes a damper mechanism that exerts an opposing force to dampen the motion exerted by the torque spring.
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公开(公告)号：USD1010107S1
公开(公告)日：2024-01-02
申请号：US29848003
申请日：2022-07-29
Applicant: AMGEN INC.
Designer： Matias Melander , Bjarke Lykke Ludvig Svendsen , Christian Plambech , Dylan Bourelle , Jakob Halkjaer Pedersen , Joshua J. Dudman , Emil Gram Spork
Abstract: FIG. 1 is a perspective view showing a new design for a handheld drug delivery device;
FIG. 2 is a front view of the handheld drug delivery device of FIG. 1;
FIG. 3 is a rear view of the handheld drug delivery device of FIG. 1;
FIG. 4 is a right-side view of the handheld drug delivery device of FIG. 1;
FIG. 5 is a left-side view of the handheld drug delivery device of FIG. 1;
FIG. 6 is a top view of the handheld drug delivery device of FIG. 1;
FIG. 7 is a bottom view of the handheld drug delivery device of FIG. 1; and,
FIG. 8 is a perspective view of the handheld drug delivery device of FIG. 1 with its cap removed.
The broken lines show portions of the handheld drug delivery device that form no part of the claimed design.-
Patent Agency Ranking
公开(公告)号：US20230138654A1
公开(公告)日：2023-05-04
申请号：US16609466
申请日：2018-06-04
Applicant: AMGEN INC.
Inventor： Adam B. McCullough , Ronald Forster , Joseph Michael Iglesias , Matias Melander , Rasmus Øhelschlaeger , Christian Plambech , Lars Stenholt , Bjarke Lykke Ludvig Svendsen
Abstract: An injector includes a housing having a syringe assembly and an actuating mechanism at least partially disposed within the housing. The syringe assembly includes a syringe barrel that stores a medicament to be injected into a user, a needle assembly, and a filter member disposed adjacent to the needle assembly. The actuating mechanism is operatively coupled to the syringe assembly and includes a torque spring that exerts a torque to urge the medicament through the filter member to be injected into the user. The actuating mechanism further includes a damper mechanism that exerts an opposing force to dampen the motion exerted by the torque spring.
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公开(公告)号：US12208062B2
公开(公告)日：2025-01-28
申请号：US16072767
申请日：2017-02-06
Applicant: AMGEN INC.
Inventor： Hans Stenberg Knudsen , Matias Melander , Jakob Halkjaer Pedersen
Abstract: The present invention relates to a pharmaceutical adaptor system. The pharmaceutical adaptor system comprises a syringe assembly having an axial extension and comprising a first end part and a second end part, the first end part having a male tubular projection, the syringe assembly comprising a syringe and a connecting element having a first mechanical connection part, a unit such as a needle, a vial, a catheter or an IV line, and an adaptor providing fluid communication between the syringe and the unit and having a second mechanical connection part configured to engage with the first mechanical connection part in an engagement direction, thereby in fully engaged position preventing further relative axial movement between the adaptor and the male tubular projection, wherein the adaptor comprises a sealing element configured to receive the male tubular projection and provide sealing between the male tubular projection and the adaptor. The present invention also relates to a pharmaceutical kit system comprising a pharmaceutical adaptor system according to the present invention.
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公开(公告)号：US12151089B2
公开(公告)日：2024-11-26
申请号：US17273663
申请日：2019-10-04
Applicant: AMGEN INC.
Inventor： Jakob Halkjaer Pedersen , Matias Melander
Abstract: A drug delivery device includes a housing defining a shell having a proximal end and a distal end and a longitudinal axis extending between the proximal end and the distal end, a needle assembly at least partially disposed within the housing at the proximal end, a drive assembly at least partially disposed within the housing and operably coupled to the needle assembly, and an audible indicator operably coupled to the drive assembly. The needle assembly includes a syringe containing a medicament and a needle or a cannula. The drive assembly is movable between an initial position and a second position that results in the medicament being expelled from the syringe. Upon the drive assembly being positioned in the second position, the audible indicator engages the drive assembly to generate an audible sound indicating the medicament has been expelled from the syringe.
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公开(公告)号：US12053617B2
公开(公告)日：2024-08-06
申请号：US16601824
申请日：2019-10-15
Applicant: AMGEN INC.
Inventor： Matias Melander , Jakob Halkjaer Pedersen , Christian Plambech , Adam B. McCullough , Julian Jazayeri
CPC classification number: A61M5/24 , A61M5/3129 , A61M5/3148 , A61M5/2033 , A61M2005/208 , A61M2005/2086 , A61M2005/3143 , A61M5/31585 , A61M2005/3267
Abstract: A drug delivery device includes a housing defining a shell having a proximal and a distal end, a needle assembly at least partially disposed within the housing at the proximal end, a drive assembly at least partially disposed within the housing, and a damper mechanism at least partially disposed within the housing adjacent to the distal end. The housing further defines a longitudinal axis extending between the proximal end and the distal end. The needle assembly includes a syringe barrel containing a medicament and a needle or a cannula. The drive assembly is operably coupled to the needle assembly to urge the medicament through the needle or cannula. The damper mechanism is operably coupled to the drive assembly and the housing. Upon activating the drive assembly, the damper mechanism dampens an effect thereof.
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