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公开(公告)号:US12098192B2
公开(公告)日:2024-09-24
申请号:US18638307
申请日:2024-04-17
Applicant: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
Inventor: Bernhard Mueller , Andreas Popp , Jennifer M. Perez
IPC: C07K16/28 , C07K16/18 , G01N33/566 , A61K39/00
CPC classification number: C07K16/18 , C07K16/28 , G01N33/566 , A61K2039/505 , C07K2317/24 , C07K2317/565 , C07K2317/92
Abstract: Provided herein are methods of using the antibodies that bind to RGMc to treat and diagnose iron-related disorders.
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公开(公告)号:US12098189B2
公开(公告)日:2024-09-24
申请号:US17034454
申请日:2020-09-28
Applicant: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
Inventor: Bernhard Mueller , Andreas Popp , Jennifer M. Perez
IPC: A61P7/06 , C07K16/18 , C07K16/28 , G01N33/566 , A61K39/00
CPC classification number: C07K16/18 , C07K16/28 , G01N33/566 , A61K2039/505 , C07K2317/24 , C07K2317/565 , C07K2317/92
Abstract: Provided herein are methods of using the antibodies that bind to RGMc to treat and diagnose iron-related disorders.
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公开(公告)号:US09636398B2
公开(公告)日:2017-05-02
申请号:US13714222
申请日:2012-12-13
Applicant: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
Inventor: Gangamani S. Beligere , Shamila Manoj , Elaine M. Brate , Frank C. Grenier , David J. Hawksworth , Robert N. Ziemann , Larry G. Birkenmeyer , Bernhard Mueller , Andreas Popp , Susan Brophy
IPC: A61K39/00 , C07K16/00 , C07K16/28 , A61K39/395 , G01N33/68 , C07K16/22 , G01N33/564 , G01N33/566 , G01N33/574
CPC classification number: A61K39/3955 , A61K2039/505 , C07K16/22 , G01N33/564 , G01N33/566 , G01N33/574 , G01N33/6893 , G01N2800/085 , G01N2800/26 , G01N2800/347
Abstract: Provided herein are antibodies and methods of using the antibodies to treat, prevent, modulate, attenuate and diagnose iron-related disorders.
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14.
公开(公告)号:US20190276526A1
公开(公告)日:2019-09-12
申请号:US16166702
申请日:2018-10-22
Applicant: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
Inventor: Bernhard Mueller , Lili Huang , Philip D. Bardwell , Yuliya Kutskova , John Memmott
Abstract: Provided herein are antibodies and methods of using the antibodies to treat and diagnose neurite degenerative diseases and disorders.
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公开(公告)号:US20150183867A1
公开(公告)日:2015-07-02
申请号:US14644524
申请日:2015-03-11
Applicant: AbbVie Inc.
Inventor: Tariq Ghayur , Alfred Hahn , Bernhard Mueller
CPC classification number: C07K16/2869 , A61K39/3955 , A61K45/06 , A61K47/6843 , A61K47/6845 , A61K47/6849 , C07K16/18 , C07K16/22 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/248 , C07K16/28 , C07K16/2803 , C07K16/2863 , C07K16/2887 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/53 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/626 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , G01N33/6863 , G01N2333/525 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/58
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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16.COMPOSITION AND METHOD FOR THE DIAGNOSIS AND TREATMENT OF DISEASES ASSOCIATED WITH NEURITE DEGENERATION 有权
Title translation: 诊断和治疗与神经衰弱相关的疾病的组合物和方法公开(公告)号:US20150118156A1
公开(公告)日:2015-04-30
申请号:US14580818
申请日:2014-12-23
Applicant: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
Inventor: Bernhard Mueller , Lili Huang , Philip D. Bardwell , Yuliya Kutskova , John Memmott
IPC: C07K16/22 , G01N33/68 , A61K51/10 , A61K39/395 , A61K49/00
CPC classification number: C07K16/22 , A61K39/3955 , A61K49/0002 , A61K49/0058 , A61K51/1018 , A61K51/1021 , A61K2039/505 , C07B59/008 , C07B2200/05 , C07K16/18 , C07K16/28 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/624 , C07K2317/76 , G01N33/6896 , G01N2333/705 , G01N2800/28 , G01N2800/285
Abstract: Provided herein are antibodies and methods of using the antibodies to treat and diagnose neurite degenerative diseases and disorders.
Abstract translation: 本文提供了使用抗体治疗和诊断神经突变性疾病和病症的抗体和方法。
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17.COMPOSITION AND METHOD FOR THE DIAGNOSIS AND TREATMENT OF DISEASES ASSOCIATED WITH NEURITE DEGENERATION 审中-公开
Title translation: 诊断和治疗与神经衰弱相关的疾病的组合物和方法公开(公告)号:US20140023659A1
公开(公告)日:2014-01-23
申请号:US14033707
申请日:2013-09-23
Applicant: AbbVie Inc. , AbbVie Deutschland GmbH & Co. KG
Inventor: Bernhard Mueller , Lili Huang , Philip D. Bardwell , Yuliya Kutskova , John Memmott
IPC: C07K16/22
CPC classification number: C07K16/22 , A61K39/3955 , A61K49/0002 , A61K49/0058 , A61K51/1018 , A61K51/1021 , A61K2039/505 , C07B59/008 , C07B2200/05 , C07K16/18 , C07K16/28 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/624 , C07K2317/76 , G01N33/6896 , G01N2333/705 , G01N2800/28 , G01N2800/285
Abstract: Provided herein are antibodies and methods of using the antibodies to treat and diagnose neurite degenerative diseases and disorders.
Abstract translation: 本文提供了使用抗体治疗和诊断神经突变性疾病和病症的抗体和方法。
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公开(公告)号:US10822403B2
公开(公告)日:2020-11-03
申请号:US16179515
申请日:2018-11-02
Applicant: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
Inventor: Bernhard Mueller , Andreas Popp , Jennifer M. Perez
IPC: C07K16/28 , C07K16/18 , G01N33/566 , A61K39/00
Abstract: Provided herein are methods of using the antibodies that bind to RGMc to treat and diagnose iron-related disorders.
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公开(公告)号:US10106602B2
公开(公告)日:2018-10-23
申请号:US15155815
申请日:2016-05-16
Applicant: ABBVIE DEUTSCHLAND GMBH & CO. KG , ABBVIE INC.
Inventor: Bernhard Mueller , Lili Huang , Philip D. Bardwell , Yuliya Kutskova , John Memmott
IPC: A61K39/35 , C07K16/00 , C07K16/18 , C07K16/22 , C07K16/28 , A61K39/395 , A61K49/00 , A61K51/10 , G01N33/68 , C07B59/00 , A61K39/00
Abstract: Provided herein are anti-Repulsive Guidance Molecule a (RGMa) antibodies and methods of using the antibodies to treat and diagnose neurite degenerative diseases and disorders.
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20.BLOOD-BRAIN-BARRIER DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF 审中-公开
Title translation: 血脑屏障双重可变域免疫球蛋白及其用途公开(公告)号:US20160032000A1
公开(公告)日:2016-02-04
申请号:US14720592
申请日:2015-05-22
Applicant: AbbVie Inc.
Inventor: Tariq Ghayur , Alfred Hahn , Bernhard Mueller
CPC classification number: C07K16/2869 , A61K39/3955 , A61K45/06 , A61K47/6843 , A61K47/6845 , A61K47/6849 , C07K16/18 , C07K16/22 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/248 , C07K16/28 , C07K16/2803 , C07K16/2863 , C07K16/2887 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/53 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/626 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , G01N33/6863 , G01N2333/525 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/58
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白,制备方法,具体涉及用于预防,诊断和/或治疗疾病的用途。
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