公开(公告)号：US20140058499A1

公开(公告)日：2014-02-27

申请号：US14042512

申请日：2013-09-30

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Mikael Trollsas ,  Michael H. Ngo ,  Boris Anukhin ,  Alexander Nikanorov ,  Syed Hossainy ,  John E. Papp ,  Dudley Jayasinghe ,  Zella Solter

IPC: A61F2/915

CPC classification number: A61F2/958 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/825 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2002/91575 ,  A61F2002/9522 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0019 ,  A61F2210/0076 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2250/0067 ,  A61F2250/0096 ,  A61F2250/0098 ,  A61L27/00 ,  A61L31/06 ,  A61L31/14 ,  B21D39/046 ,  B29C35/08 ,  B29C2035/0838 ,  B29K2067/046 ,  B29L2023/00 ,  B29L2031/7543 ,  Y10T29/49826 ,  Y10T29/4987 ,  Y10T29/49908 ,  Y10T29/49925 ,  Y10T29/49927 ,  C08L67/04 ,  C08L71/02

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells.

Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 支架在被气囊部署之后，在支架的直径被挤压或压碎50％后，提供约90％的压碎回收率。 支架具有图案，其包括连接连接封闭单元的链接的非对称封闭单元。

公开(公告)号：US20140010858A1

公开(公告)日：2014-01-09

申请号：US13903773

申请日：2013-05-28

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： John J. Stankus ,  O. Mikael Trollsas ,  Michael H. Ngo

IPC: A61L27/18 ,  A61L27/54 ,  A61L27/34

CPC classification number: A61L27/18 ,  A61L27/34 ,  A61L27/54 ,  A61L2400/16 ,  C08G2230/00 ,  C08G2280/00 ,  C08L75/04

Abstract: The present invention is directed to polymeric compositions comprising a biodegradable copolymer that possesses shape-memory properties and implantable devices (e.g., drug-delivery stents) formed of materials (e.g., a coating) containing such compositions. The polymeric compositions can also contain at least one non-fouling moiety, at least additional biocompatible polymer, at least one biobeneficial material, at least one bioactive agent, or a combination thereof. The polymeric compositions are formulated to possess good mechanical, physical and biological properties. Moreover, implantable devices formed of materials comprising such compositions can be delivered to the treatment site in a conveniently compressed size and then can expand to dimensions appropriate for their medical functions.

Abstract translation: 本发明涉及包含具有形状记忆特性的可生物降解的共聚物和由含有这种组合物的材料（例如涂层）形成的可植入装置（例如药物递送支架）的聚合物组合物。 聚合物组合物还可含有至少一种非结垢部分，至少另外的生物相容性聚合物，至少一种生物有益材料，至少一种生物活性剂或其组合。 将聚合物组合物配制成具有良好的机械，物理和生物学特性。 此外，由包含这种组合物的材料形成的可植入装置可以以方便的压缩尺寸输送到治疗部位，然后可扩大到适于其医疗功能的尺寸。

公开(公告)号：US11324614B2

公开(公告)日：2022-05-10

申请号：US16172599

申请日：2018-10-26

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Mikael Trollsas ,  Michael H. Ngo ,  Boris Anukhin ,  Alexander Nikanorov ,  Syed Hossainy ,  John E. Papp ,  Dudley Jayasinghe ,  Zella Solter

IPC: A61F2/915 ,  A61F2/82 ,  A61F2/958 ,  A61F2/89 ,  B21D39/04 ,  A61F2/91 ,  A61L31/06 ,  A61L31/14 ,  A61F2/95 ,  A61L27/00 ,  A61F2/86 ,  A61F2/844 ,  B29C35/08 ,  B29K67/00 ,  B29L23/00 ,  B29L31/00

Abstract: A medical device includes a polymer stent (or scaffold) crimped to a catheter balloon. The stent, after being expanded from a crimped state by the balloon, provides a crush recovery of about 90% of its expanded diameter after being pinched or crushed by an amount equal to about 50% of the expanded diameter. The stent has a pattern including a W-shaped or W-V shaped closed cell and links connecting the closed cells.

公开(公告)号：US20190060097A1

公开(公告)日：2019-02-28

申请号：US16172599

申请日：2018-10-26

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Mikael Trollsas ,  Michael H. Ngo ,  Boris Anukhin ,  Alexander Nikanorov ,  Syed Hossainy ,  John E. Papp ,  Dudley Jayasinghe ,  Zella Solter

IPC: A61F2/958 ,  A61L31/06 ,  A61L31/14 ,  B21D39/04 ,  B29C35/08 ,  A61F2/915 ,  A61F2/844 ,  A61F2/86 ,  A61L27/00 ,  A61F2/91 ,  A61F2/82 ,  A61F2/95 ,  A61F2/89 ,  B29K67/00 ,  B29L31/00 ,  B29L23/00

Abstract: A medical device includes a polymer stent (or scaffold) crimped to a catheter balloon. The stent, after being expanded from a crimped state by the balloon, provides a crush recovery of about 90% of its expanded diameter after being pinched or crushed by an amount equal to about 50% of the expanded diameter. The stent has a pattern including a W-shaped or W-V shaped closed cell and links connecting the closed cells.

公开(公告)号：US20180318116A1

公开(公告)日：2018-11-08

申请号：US16034285

申请日：2018-07-12

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Erik David Eli ,  Syed Hossainy ,  Mikael Trollsas ,  Michael H. Ngo ,  Stephen Pacetti ,  Michael Green ,  John Papp

IPC: A61F2/915 ,  A61F2/91 ,  A61F2/82 ,  A61F2/958

CPC classification number: A61F2/915 ,  A61F2/91 ,  A61F2/958 ,  A61F2002/828 ,  A61F2002/91575 ,  A61F2002/91591 ,  A61F2210/0004 ,  A61F2220/0075 ,  A61F2220/0091

Abstract: A scaffold is formed by several segments joined or connected to each other by only at least one coupling. The coupling decouples the segments in the axial direction over a finite distance of axial displacement. The scaffold when implanted in a peripheral vessel reduces loading on rings of a segment due to the decoupling of the segments in the axial direction over the finite distance.

公开(公告)号：US09763818B2

公开(公告)日：2017-09-19

申请号：US14085716

申请日：2013-11-20

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Mikael Trollsas ,  Michael H. Ngo ,  Boris Anukhin ,  Alexander Nikanorov ,  Syed Hossainy ,  John E. Papp ,  Dudley Jayasinghe ,  Zella Solter

IPC: A61F2/958 ,  A61F2/91 ,  A61L27/00 ,  A61L31/06 ,  A61F2/86 ,  A61F2/844 ,  B29C35/08 ,  A61L31/14 ,  A61F2/89 ,  A61F2/82 ,  A61F2/915 ,  A61F2/95 ,  B29K67/00 ,  B29L23/00 ,  B29L31/00

CPC classification number: A61F2/958 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/825 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2002/91575 ,  A61F2002/9522 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0019 ,  A61F2210/0076 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2250/0067 ,  A61F2250/0096 ,  A61F2250/0098 ,  A61L27/00 ,  A61L31/06 ,  A61L31/14 ,  B21D39/046 ,  B29C35/08 ,  B29C2035/0838 ,  B29K2067/046 ,  B29L2023/00 ,  B29L2031/7543 ,  Y10T29/49826 ,  Y10T29/4987 ,  Y10T29/49908 ,  Y10T29/49925 ,  Y10T29/49927 ,  C08L67/04 ,  C08L71/02

Abstract: A method of crimping a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the maker support structures.

公开(公告)号：US20160030212A1

公开(公告)日：2016-02-04

申请号：US14880905

申请日：2015-10-12

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： John Stankus ,  Yunbing Wang ,  Mikael Trollsas ,  Syed Faiyaz Ahmed Hossainy ,  Michael H. Ngo ,  Dariush Davalian

IPC: A61F2/915

CPC classification number: A61F2/915 ,  A61F2210/0004 ,  A61F2210/0057 ,  A61F2230/0013 ,  A61F2230/0054 ,  A61L31/041 ,  A61L31/129 ,  A61L31/141 ,  A61L31/148

Abstract: Bioabsorbable scaffolds are disclosed with a rigid polymer component and a rubbery polymer component. The rubbery polymer component is miscible, partially miscible, or immiscible with the rigid polymer component.

公开(公告)号：US20140075735A1

公开(公告)日：2014-03-20

申请号：US14085716

申请日：2013-11-20

Applicant: Abbott Cardiovascular Systems Inc,

Inventor： Mikael Trollsas ,  Michael H. Ngo ,  Boris Anukhin ,  Alexander Nikanorov ,  Syed Hossainy ,  John E. Papp ,  Dudley Jayasinghe ,  Zelia Salter

IPC: A61F2/958

CPC classification number: A61F2/958 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/825 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2002/91575 ,  A61F2002/9522 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0019 ,  A61F2210/0076 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2250/0067 ,  A61F2250/0096 ,  A61F2250/0098 ,  A61L27/00 ,  A61L31/06 ,  A61L31/14 ,  B21D39/046 ,  B29C35/08 ,  B29C2035/0838 ,  B29K2067/046 ,  B29L2023/00 ,  B29L2031/7543 ,  Y10T29/49826 ,  Y10T29/4987 ,  Y10T29/49908 ,  Y10T29/49925 ,  Y10T29/49927 ,  C08L67/04 ,  C08L71/02

Abstract: A method of crimping a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the maker support structures.

Abstract translation: 公开了一种卷曲支架的方法。 支架包括最小卷曲直径，使得在最小卷曲直径处，标记支撑结构所在的一对支架环不与标记支撑结构接触。 本发明的支架的卷曲轮廓可以与同一支架的卷曲轮廓一样小，但没有制造者支撑结构。

公开(公告)号：US20140067044A1

公开(公告)日：2014-03-06

申请号：US14042496

申请日：2013-09-30

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Mikael Trollsas ,  Michael H. Ngo ,  Boris Anukhin ,  Alexander Nikanorov ,  Syed Hossainy ,  John E. Papp ,  Dudley Jayasingle ,  Zella Solter

IPC: A61F2/86

CPC classification number: A61F2/958 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/825 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2002/91575 ,  A61F2002/9522 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0019 ,  A61F2210/0076 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2250/0067 ,  A61F2250/0096 ,  A61F2250/0098 ,  A61L27/00 ,  A61L31/06 ,  A61L31/14 ,  B21D39/046 ,  B29C35/08 ,  B29C2035/0838 ,  B29K2067/046 ,  B29L2023/00 ,  B29L2031/7543 ,  Y10T29/49826 ,  Y10T29/4987 ,  Y10T29/49908 ,  Y10T29/49925 ,  Y10T29/49927 ,  C08L67/04 ,  C08L71/02

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells.

公开(公告)号：US11337835B2

公开(公告)日：2022-05-24

申请号：US16674607

申请日：2019-11-05

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： John J. Stankus ,  Hugh Zhao ,  Mikael Trollsas ,  Syed Faiyaz Ahmed Hossainy ,  Michael H. Ngo ,  Yunbing Wang ,  Benjamyn Serna

IPC: A61F2/86 ,  A61F2/915 ,  A61L31/04 ,  A61L31/14 ,  A61L31/16 ,  A61L31/06

Abstract: Bioabsorbable scaffolds having high crush recoverability, high fracture resistance, and reduced or no recoil due to self expanding properties at physiological conditions are disclosed. The scaffolds are made from a random copolymer of PLLA and a rubbery polymer such as polycaprolactone.