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    Methods, Systems and Devices for Establising Communication Between Hollow Organs and Tissue Lumens
    12.
    发明申请
    Methods, Systems and Devices for Establising Communication Between Hollow Organs and Tissue Lumens 有权
    用于建立空心器官和组织流明之间的通信的方法，系统和装置

    公开(公告)号：US20090036872A1

    公开(公告)日：2009-02-05

    申请号：US11664480

    申请日：2005-10-06

    申请人： Peter J. Fitzgerald ,  Brain K. Courtney ,  Ali Hassan

    发明人： Peter J. Fitzgerald ,  Brain K. Courtney ,  Ali Hassan

    IPC分类号： A61M25/16

    CPC分类号： A61M25/0082 ,  A61M25/0068 ,  A61M25/0127

    摘要： Methods, systems and devices for establishing communication between organs and/or tissue lumens. The devices include catheters having magnetized distal ends which are configured to magnetically couple to each other such that a coaxial alignment is established between two or more catheters. The systems include two or more the subject catheters. The methods include use of the catheters and magnetically coupling them to establish a continuous passageway between them.

    摘要翻译： 用于建立器官和/或组织腔之间的通信的方法，系统和装置。 这些装置包括具有磁化远端的导管，其构造成彼此磁耦合，使得在两个或更多个导管之间建立同轴对准。 系统包括两个或更多个主题导管。 这些方法包括使用导管并将其磁耦合以在它们之间建立连续的通道。

    Methods and kits for locally administering an active agent to an interstitial space of a host
    13.
    发明授权
    Methods and kits for locally administering an active agent to an interstitial space of a host 失效
    用于将活性剂本地施用于宿主的间质空间的方法和试剂盒

    公开(公告)号：US06346098B1

    公开(公告)日：2002-02-12

    申请号：US09519950

    申请日：2000-03-07

    申请人： Paul G. Yock ,  Ali H. Hassan ,  Alan Ching Yeun Yeung ,  Andrew Carter ,  Mehrdad Rezaee ,  Niall Herity ,  Sidney Lo ,  Peter J. Fitzgerald

    发明人： Paul G. Yock ,  Ali H. Hassan ,  Alan Ching Yeun Yeung ,  Andrew Carter ,  Mehrdad Rezaee ,  Niall Herity ,  Sidney Lo ,  Peter J. Fitzgerald

    IPC分类号： A61M2500

    CPC分类号： A61K48/00 ,  A61K38/00 ,  A61M37/00

    摘要： Methods are provided for locally administering an agent to a host. Specifically, the subject methods provide for the local administration of an agent to an interstitial space of a host. In the subject methods, an agent is retroinfused into a vessel of a host, typically a vein, under conditions sufficient for the agent to enter an interstitial space of the host proximal to the vessel location into which the agent is retroinfused. In practicing the subject methods, the agent is administered to the host in combination with the production of vascular stress at the site of administration, where the vascular tissue stress is sufficient to provide for transport of the agent from the vascular site of deposition into the target interstitial space. In a preferred embodiment, the agent is retroinfused at a pressure sufficient to provide for mechanical stress on the vessel proximal to the target interstitial space. Also provided are kits for use in practicing the subject methods. The subject invention finds use in the local administration of a variety of different agents for treatment of a variety of different disease or other conditions.

    摘要翻译： 提供用于向宿主局部施用药剂的方法。 具体地，主题方法提供了代理人对主机的间隙空间的本地管理。 在本发明的方法中，在足以使试剂进入宿主的间隙空间的条件下，将试剂逆向灌注到宿主（通常为静脉）的血管中，所述间质空间靠近所述药剂被回输入其中的血管位置。 在实施本发明方法中，将药剂与给药部位的血管应激的产生相结合地施用于宿主，其中血管组织应激足以提供将药物从血管沉积部位输送到靶 间隙空间 在优选的实施方案中，所述试剂在足以在靠近所述靶间质空间的血管上提供机械应力的压力下进行回灌。 还提供了用于实践主题方法的套件。 本发明用于局部施用各种不同的药剂以治疗各种不同的疾病或其他病症。

    Method and apparatus for curvature detection in vessels from phase shifts of a plurality of input electrical signals
    14.
    发明授权
    Method and apparatus for curvature detection in vessels from phase shifts of a plurality of input electrical signals 失效
    用于在多个输入电信号的相移中的容器中的曲率检测的方法和装置

    公开(公告)号：US5916170A

    公开(公告)日：1999-06-29

    申请号：US158969

    申请日：1998-09-21

    申请人： Matthew L. Kolz ,  Peter J. Fitzgerald ,  Gordon S. Kino

    发明人： Matthew L. Kolz ,  Peter J. Fitzgerald ,  Gordon S. Kino

    IPC分类号： A61B8/06 ,  A61B8/12 ,  A61B8/00

    CPC分类号： A61B8/06 ,  A61B8/12 ,  A61B8/4461 ,  A61B8/445

    摘要： An ultrasound imaging apparatus for measuring the curvature of a vessel consisting of a distal transducer mounted on a transducer supporting device. A resilient deformable material is attached to the transducer supporting device and allows the angular orientation of the transducer to change based on the local vessel curvature. The ultrasound imaging apparatus emits ultrasound radiation from multiple pulsed electronic signals as the apparatus is moved through a vessel or sheath catheter at a known velocity. The distal transducer receives the scattered ultrasound radiation and differences in the phase shifts of the scattered ultrasound radiation are analyzed to detect or measure curvature.

    摘要翻译： 一种用于测量由安装在换能器支撑装置上的远端换能器组成的血管的曲率的超声波成像装置。 弹性可变形材料附接到换能器支撑装置，并且允许换能器的角度取向基于局部血管曲率而改变。 当设备以已知速度移动通过血管或鞘导管时，超声成像设备从多个脉冲电子信号发射超声波辐射。 远端换能器接收散射超声波，并分析散射超声波相移的差异，以检测或测量曲率。