公开(公告)号：US06488946B1

公开(公告)日：2002-12-03

申请号：US09936695

申请日：2001-09-17

申请人： Alain Milius ,  Alicia Roso ,  Nelly Michel

发明人： Alain Milius ,  Alicia Roso ,  Nelly Michel

IPC分类号： A61K700

CPC分类号： A61K8/4973 ,  A61K8/06 ,  A61K8/064 ,  A61K8/342 ,  A61K8/361 ,  A61K8/604 ,  A61K8/922 ,  A61K8/925 ,  A61K2800/592 ,  A61Q19/00 ,  B01F17/0092 ,  Y10S514/937 ,  Y10S514/938 ,  Y10S514/939

摘要： The present invention relates to novel stable > emulsions containing 5 to 70% by weight of an aqueous phase 20 to 90% by weight of a fatty phase; and 3 to 25% by weight of an emulsifier comprising 10 to 90% by weight, preferably 10 to 50% by weight and more preferably 10 to 40% by weight of a mixture in any proportion of an oleyl glycoside having a degree of polymerisation of between 1 and 3 and an isostearyl glycoside having a degree of polymerisation of between 1 and 3; and 90 to 10% by weight, preferably 90 to 50% by weight, and more preferably 90 to 60% by weight of a mixture in any proportion of oleyl alcohol and isostearyl alcohol and optionally 0 to 10% by weight of a co-emulsifier; 0 to 10% by weight of a stabiliser. Application: Cosmetic industry.

摘要翻译： 本发明涉及含有5-70重量％的20-90重量％脂肪相的水相的新的稳定的“油包水”乳液; 和3至25重量％的乳化剂，其包含10至90重量％，优选10至50重量％，更优选10至40重量％的任何比例的聚合度为1的油基糖苷之间的混合物 和3和聚合度为1至3的异硬脂基糖苷; 和90至10重量％，优选90至50重量％，更优选90至60重量％的任何比例的油醇和异硬脂基醇酸盐的混合物，任选地0至10重量％的共乳化剂; 0至 10％（重量）稳定剂。应用：化妆品行业。

公开(公告)号：US06464993B1

公开(公告)日：2002-10-15

申请号：US09937733

申请日：2001-09-27

申请人： Alain Milius ,  Nelly Michel ,  Bernard Branco ,  Jean-Pierre Boiteux ,  Chantal Almaric ,  Alicia Roso

发明人： Alain Milius ,  Nelly Michel ,  Bernard Branco ,  Jean-Pierre Boiteux ,  Chantal Almaric ,  Alicia Roso

IPC分类号： A61K700

CPC分类号： A61Q19/00 ,  A61K8/04 ,  A61K8/34 ,  A61K8/342 ,  A61K8/35 ,  A61K8/40 ,  A61K8/602 ,  A61K2800/75 ,  A61Q1/10 ,  A61Q17/00 ,  A61Q17/04 ,  Y10S514/937 ,  Y10S514/938 ,  Y10S514/939

摘要： The present invention relates to the use of a composition comprising: 10 to 90% by weight, preferably 10 to 50% by weight and particularly preferably 10 to 40% by weight of an isostearyl glycoside with a degree of polymerization of between 1 and 3; and 90 to 10% by weight, preferably 90 to 50% by weight and particularly preferably 90 to 60% by weight of isostearyl alcohol as an agent for improving the water resistance of a cosmetic composition.

摘要翻译： 本发明涉及组合物的用途，所述组合物包含：10至90重量％，优选10至50重量％，特别优选10至40重量％的聚合度为1至3的异硬脂基糖苷; 和90至10重量％，优选90至50重量％，特别优选90至60重量％的异硬脂醇是用于改善化妆品组合物的耐水性的试剂。

公开(公告)号：US20110311598A1

公开(公告)日：2011-12-22

申请号：US13201131

申请日：2010-02-15

申请人： Chantal Amalric ,  Alicia Roso ,  Agnes Gorce

发明人： Chantal Amalric ,  Alicia Roso ,  Agnes Gorce

IPC分类号： A61K8/06 ,  A61K8/02 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q1/14 ,  A61K8/60 ,  A61K8/92

CPC分类号： A61Q19/008 ,  A61K8/022 ,  A61K8/06 ,  A61K8/062 ,  A61K8/34 ,  A61K8/342 ,  A61K8/60 ,  A61K8/602 ,  A61K8/604 ,  A61K8/92 ,  A61K2800/412 ,  A61Q1/02 ,  A61Q1/14 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/005 ,  A61Q19/007 ,  A61Q19/04 ,  B01F17/0092

摘要： A powdery composition C1 contains for 100% of the mass: 5 to 70 mass % and more particularly 10 to 50 mass % of at least one compound of formula (I): R—O-(G)x-H, wherein R is a linear saturated aliphatic radical including 12 to 22 carbon atoms, G is the remainder of a reducing sugar selected from the group including glucose, xylose and arabinose, and x is a decimal number greater than or equal to 1 and lower than or equal to 10; 95 to 30 mass % and more particularly 90 to 50 mass % of one or more alcohols of formula (II): R′—OH, wherein R′ is a linear saturated aliphatic radical including 12 to 22 carbon atoms identical to or different from R as defined in formula (I), wherein at least 90 vol % of the particles have a diameter lower than or equal to 250 micrometers, more particularly a diameter lower than or equal to 150 micrometers.

摘要翻译： 粉末状组合物C1含有100质量％：5〜70质量％，更优选10〜50质量％的至少一种式（I）的化合物：R-O-（G）xH，其中R为直链 含有12-22个碳原子的饱和脂族基团，G是选自包括葡萄糖，木糖和阿拉伯糖的还原糖的剩余部分，x是大于或等于1且小于等于10的十进制数; 95〜30质量％，更优选为90〜50质量％的式（II）的醇或其混合物：R'-OH，其中，R'为与R相同或不同的12〜22个碳原子的直链饱和脂肪族基团 如式（I）中所定义，其中至少90体积％的颗粒具有小于或等于250微米的直径，更特别是直径小于或等于150微米。

公开(公告)号：US20090258808A1

公开(公告)日：2009-10-15

申请号：US12294364

申请日：2007-03-16

申请人： Alicia Roso ,  Chantal Amalric ,  Guy Tabacchi

发明人： Alicia Roso ,  Chantal Amalric ,  Guy Tabacchi

IPC分类号： A61K8/60 ,  C07H1/00

CPC分类号： A61Q19/10 ,  A61K8/463 ,  A61K8/602 ,  A61K8/608 ,  A61K2800/596 ,  A61Q1/14 ,  A61Q5/02

摘要： The ocular tolerance of cosmetic, dermocosmetic and dermopharmaceutical compositions is improved by the incorporation therein of an effective amount of a polyol-glycoside or of a mixture of polyol-glycosides of formula (I): R1—O-(G)-H (I) in which: —x represents a decimal number between 1 and 5 and G represents the residue of a reducing sugar, and R1 represents a radical of formula (A) —CH2—(CHOH)n—CH2—OH (A) in which n is an integer equal to 2, 3 or 4, or else R1 represents a radical of formula (B) —(CH2—CHOH—CH2—O)m—H (B) in which m is an integer equal to 1, 2 or 3. The invention also relates to new concentrates which contain compounds of formula (I), foaming and/or detergent surfactants and topically acceptable solvents, and also to processes for preparing them.

摘要翻译： 通过在其中加入有效量的多元醇糖苷或式（I）的多元醇 - 糖苷的混合物，可以改善化妆品，皮肤科和皮肤用药物组合物的眼部耐受性：R1-O-（G）-H（I ）其中：-x表示1至5之间的十进制数，G表示还原糖的残基，R 1表示式（A）-CH 2 - （CHOH）n -CH 2 -OH（A）的基团，其中 n是等于2,3或4的整数，或者R1表示式（B） - （CH2-CHOH-CH2-O）mH（B）的基团，其中m是等于1,2或3的整数 本发明还涉及含有式（I）化合物，发泡和/或洗涤剂表面活性剂和局部可接受溶剂的新浓缩物，还涉及制备它们的方法。

公开(公告)号：US20090088358A1

公开(公告)日：2009-04-02

申请号：US12298862

申请日：2007-04-16

申请人： Alicia Roso ,  Corinne Stoltz

发明人： Alicia Roso ,  Corinne Stoltz

IPC分类号： A61K8/60 ,  A61Q19/10

CPC分类号： A61Q19/10 ,  A61K8/602 ,  C11D1/29 ,  C11D1/662 ,  C11D3/0094 ,  C11D3/221

摘要： A method for improving foaming properties of cleansing and/or foaming formulations, compositions, methods for preparing them, and preparation of the topical formulations containing them are described. The method consists in including, in these formulations, an effective amount of a polyol glycoside or of a mixture of polyol glycosides of formula (I) R1—O-(G)x-H in which x is a decimal number ranging between 1 and 5, G is the residue of a reducing sugar and R1 is a radical of formula (A) —CH2—(CHOH)n—CH2—OH in which n is an integer equal to 2, 3 or 4, or else R1 is a radical of the formula (B) —(CH2—CHOH—CH2—O)m—H in which m is an integer equal to 1, 2 or 3. Compositions contain compounds of formula (I) or mixtures of compounds of formula (I), foaming and/or detergent surfactants and topically acceptable solvents. Can be used in the cosmetics, dermopharmaceutical and pharmaceutical field.

摘要翻译： 描述了用于改善清洁和/或发泡制剂的发泡性能的方法，组合物，其制备方法以及含有它们的局部制剂的制备。 该方法包括在这些制剂中包含有效量的多元醇糖苷或式（I）R1-O-（G）xH的多元醇糖苷的混合物，其中x是1至5之间的十进制数， G是还原糖的残基，R 1是式（A）-CH 2 - （CHOH）n -CH 2 -OH的基团，其中n是等于2,3或4的整数，或者R 1是 式（B） - （CH2-CHOH-CH2-O）mH，其中m为等于1,2或3的整数。组合物含有式（I）化合物或式（I）化合物的混合物，发泡和 /或洗涤剂表面活性剂和局部可接受的溶剂。 可用于化妆品，皮肤药物和制药领域。

公开(公告)号：US07915208B2

公开(公告)日：2011-03-29

申请号：US12298862

申请日：2007-04-16

申请人： Alicia Roso ,  Corinne Stoltz

发明人： Alicia Roso ,  Corinne Stoltz

IPC分类号： A61K8/60 ,  A61K8/73 ,  A61Q19/10

CPC分类号： A61Q19/10 ,  A61K8/602 ,  C11D1/29 ,  C11D1/662 ,  C11D3/0094 ,  C11D3/221

摘要： A method for improving foaming properties of cleansing and/or foaming formulations, compositions, methods for preparing them, and preparation of the topical formulations containing them are described. The method consists in including, in these formulations, an effective amount of a polyol glycoside or of a mixture of polyol glycosides of formula (I) R1—O-(G)x-H in which x is a decimal number ranging between 1 and 5, G is the residue of a reducing sugar and R1 is a radical of formula (A) —CH2—(CHOH)n—CH2—OH in which n is an integer equal to 2, 3 or 4, or else R1 is a radical of the formula (B) —(CH2—CHOH—CH2—O)m—H in which m is an integer equal to 1, 2 or 3. Compositions contain compounds of formula (I) or mixtures of compounds of formula (I), foaming and/or detergent surfactants and topically acceptable solvents. Can be used in the cosmetics, dermopharmaceutical and pharmaceutical field.

摘要翻译： 描述了用于改善清洁和/或发泡制剂的发泡性能的方法，组合物，其制备方法以及含有它们的局部制剂的制备。 该方法包括在这些制剂中包含有效量的多元醇糖苷或式（I）R1-O-（G）xH的多元醇糖苷的混合物，其中x是1至5之间的十进制数， G是还原糖的残基，R 1是式（A）-CH 2 - （CHOH）n -CH 2 -OH的基团，其中n是等于2,3或4的整数，或者R 1是 式（B） - （CH2-CHOH-CH2-O）m-H，其中m是等于1,2或3的整数。组合物含有式（I）化合物或式（I）化合物的混合物， 发泡和/或洗涤剂表面活性剂和局部可接受的溶剂。 可用于化妆品，皮肤药物和制药领域。

公开(公告)号：US20050101727A1

公开(公告)日：2005-05-12

申请号：US10799373

申请日：2004-03-12

申请人： Chantal Amalric ,  Alicia Roso ,  Guy Tabacchi

发明人： Chantal Amalric ,  Alicia Roso ,  Guy Tabacchi

IPC分类号： A61K8/06 ,  A61K8/81 ,  A61Q17/04 ,  C08J3/00

CPC分类号： A61K8/042 ,  A61K8/064 ,  A61K8/8158 ,  A61Q17/04

摘要： A composition and its method of production. This composition includes both an oily external phase and a gelled aqueous phase, wherein the aqueous phase is 60 to 98% by weight of the total composition. Additional features of the composition include the aqueous phase containing a polyelectrolyte in which the ionic sites are combined with their counterions. The oily phase of the composition contains one or more oils and also an emulsifying system with a lipophilic nature. The composition may be utilized in the following applications: cosmetic, pharmaceutical, veterinary, or detergent preparations.

摘要翻译： 一种组成及其生产方法。 该组合物包括油性外相和凝胶状水相，其中水相为总组合物重量的60-98％。 组合物的其它特征包括含有聚电解质的水相，其中离子位点与其抗衡离子结合。 组合物的油相含有一种或多种油以及具有亲脂性的乳化体系。 组合物可用于以下应用：化妆品，药​​物，兽医或洗涤剂制剂。

公开(公告)号：US08821902B2

公开(公告)日：2014-09-02

申请号：US13201131

申请日：2010-02-15

申请人： Chantal Amalric ,  Alicia Roso ,  Agnes Gorce

发明人： Chantal Amalric ,  Alicia Roso ,  Agnes Gorce

IPC分类号： A61K8/02 ,  A01N25/00 ,  A61K47/00 ,  B01F17/00 ,  A61K8/06 ,  A61K8/34 ,  A61K8/60 ,  A61Q19/04 ,  A61Q19/00 ,  A61Q17/04 ,  A61Q1/14 ,  A61Q1/02

CPC分类号： A61Q19/008 ,  A61K8/022 ,  A61K8/06 ,  A61K8/062 ,  A61K8/34 ,  A61K8/342 ,  A61K8/60 ,  A61K8/602 ,  A61K8/604 ,  A61K8/92 ,  A61K2800/412 ,  A61Q1/02 ,  A61Q1/14 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/005 ,  A61Q19/007 ,  A61Q19/04 ,  B01F17/0092

摘要： A powdery composition C1 contains for 100% of the mass: 5 to 70 mass % and more particularly 10 to 50 mass % of at least one compound of formula (I): R—O-(G)x-H, wherein R is a linear saturated aliphatic radical including 12 to 22 carbon atoms, G is the remainder of a reducing sugar selected from the group including glucose, xylose and arabinose, and x is a decimal number greater than or equal to 1 and lower than or equal to 10; 95 to 30 mass % and more particularly 90 to 50 mass % of one or more alcohols of formula (II): R′—OH, wherein R′ is a linear saturated aliphatic radical including 12 to 22 carbon atoms identical to or different from R as defined in formula (I), wherein at least 90 vol % of the particles have a diameter lower than or equal to 250 micrometers, more particularly a diameter lower than or equal to 150 micrometers.

摘要翻译： 粉末状组合物C1含有100质量％：5〜70质量％，更优选10〜50质量％的至少一种式（I）的化合物：R-O-（G）xH，其中R为直链 含有12-22个碳原子的饱和脂族基团，G是选自包括葡萄糖，木糖和阿拉伯糖在内的还原糖的剩余部分，x是大于或等于1且小于等于10的十进制数; 95〜30质量％，更优选为90〜50质量％的式（II）的醇或其混合物：R'-OH，其中，R'为与R相同或不同的12〜22个碳原子的直链饱和脂肪族基团 如式（I）中所定义，其中至少90体积％的颗粒具有小于或等于250微米的直径，更特别是直径小于或等于150微米。

公开(公告)号：US20080200534A1

公开(公告)日：2008-08-21

申请号：US12090485

申请日：2006-10-17

申请人： Alicia Roso ,  Christine Garcia

发明人： Alicia Roso ,  Christine Garcia

IPC分类号： A61K31/401

CPC分类号： A61K8/44 ,  A61K8/37 ,  A61K8/375 ,  A61K8/4993 ,  A61K31/401 ,  A61K47/14 ,  A61Q19/06

摘要： Composition (A) containing, for 100% of its mass: from 10 mass % to 90 mass % of N-lauroyl proline (I) and from 10 mass % to 90 mass % of an ester (II) of anhydrohexitol and of a saturated or unsaturated, linear or branched aliphatic carboxylic acid containing from 12 to 20 carbon atoms optionally substituted with one or more hydroxyl groups, or of a mixture of esters (II); use thereof for preparing a medicament with lipolytic activity, intended to induce slimming of the human or animal body and/or the reduction of cellulite or of the orange-feel appearance; cosmetic formulation or therapeutic composition containing same; process for the preparation thereof and process for the solubilization of N-lauroyl proline (I) in a liquid medium.

摘要翻译： 对于其质量的100％，含有10质量％至90质量％的N-月桂酰脯氨酸（I）和10质量％至90质量％的脱水己糖酯（II）和饱和的 或任选被一个或多个羟基取代的含有12至20个碳原子的不饱和直链或支链脂族羧酸，或酯（II）的混合物; 其用于制备旨在诱导人体或动物身体减轻和/或减少脂肪团或橙色感觉外观的具有消脂活性的药物; 含有它们的化妆品制剂或治疗组合物; 其制备方法以及N-月桂酰脯氨酸（I）在液体培养基中的溶解过程。

公开(公告)号：US08093221B2

公开(公告)日：2012-01-10

申请号：US12090485

申请日：2006-10-17

申请人： Alicia Roso ,  Christine Garcia

发明人： Alicia Roso ,  Christine Garcia

IPC分类号： A61K48/00

CPC分类号： A61K8/44 ,  A61K8/37 ,  A61K8/375 ,  A61K8/4993 ,  A61K31/401 ,  A61K47/14 ,  A61Q19/06

摘要： Composition (A) containing, for 100% of its mass: from 10 mass % to 90 mass % of N-lauroyl proline (I) and from 10 mass % to 90 mass % of an ester (II) of anhydrohexitol and of a saturated or unsaturated, linear or branched aliphatic carboxylic acid containing from 12 to 20 carbon atoms optionally substituted with one or more hydroxyl groups, or of a mixture of esters (II); use thereof for preparing a medicament with lipolytic activity, intended to induce slimming of the human or animal body and/or the reduction of cellulite or of the orange-feel appearance; cosmetic formulation or therapeutic composition containing same; process for the preparation thereof and process for the solubilization of N-lauroyl proline (I) in a liquid medium.

摘要翻译： 对于其质量的100％，含有10质量％至90质量％的N-月桂酰脯氨酸（I）和10质量％至90质量％的脱水己糖酯（II）和饱和的 或任选被一个或多个羟基取代的含有12至20个碳原子的不饱和直链或支链脂族羧酸，或酯（II）的混合物; 其用于制备旨在诱导人体或动物身体减轻和/或减少脂肪团或橙色感觉外观的具有消脂活性的药物; 含有它们的化妆品制剂或治疗组合物; 其制备方法以及N-月桂酰脯氨酸（I）在液体培养基中的溶解过程。