公开(公告)号：US20240099355A1

公开(公告)日：2024-03-28

申请号：US18534105

申请日：2023-12-08

Applicant: Altria Client Services LLC

Inventor： Feng GAO ,  Frank Scott ATCHLEY ,  Gregory James GRISCIK ,  Christopher Joseph DINOVI ,  Phillip M. HULAN

IPC: A24B13/00 ,  A24B15/16

CPC classification number: A24B13/00 ,  A24B15/16

Abstract: An oral product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-soluble polymer matrix, cellulosic fibers embedded in the mouth-soluble polymer matrix, and nicotine or a derivative thereof dispersed in the mouth-soluble polymer matrix. The oral product is adapted to release the nicotine or a derivative thereof from the body when the body is received within the oral cavity and exposed to saliva.

公开(公告)号：US20220313614A1

公开(公告)日：2022-10-06

申请号：US17223746

申请日：2021-04-06

Applicant: Altria Client Services LLC

Inventor： Feng GAO ,  Benjamin L. RAGLAND ,  David J. PHILLIPS ,  Rebecca M. GRAY ,  Pauline MARCQ ,  Christian SCHUH ,  Krasnodara N. CAMERON

IPC: A61K9/50 ,  A61K9/00 ,  A61K31/465 ,  A61K47/26

Abstract: A method for forming encapsulated nicotine granules (ENGs) includes heating a first mixture to form a molten mixture, the first mixture includes one or more polyols; cooling the molten mixture to a first temperature to form a cooled molten mixture; adding at least one of nicotine and one or more nicotine salts to the cooled molten mixture to form a second mixture; cooling the second mixture to a second temperature to form one or more solidified structures, where the second temperature is different from the first temperature; and fragmenting the one or more solidified structures so as to form a plurality of encapsulated nicotine granules. The first temperature may be between about 120° C. and about 200° C. The second temperature may be below a glass transition temperature (Tg) of the one or more polyols. For example, the second temperature may be between about 65° C. and about 200° C.

公开(公告)号：US20210379048A1

公开(公告)日：2021-12-09

申请号：US17411270

申请日：2021-08-25

Applicant: Altria Client Services LLC

Inventor： Feng GAO ,  Diane L. GEE ,  Phillip M. HULAN ,  Shuzhong ZHUANG ,  William J. BURKE

IPC: A61K31/465 ,  A61K9/20 ,  A61K9/00 ,  B29C48/00 ,  A61K45/06

Abstract: A nicotine lozenge includes a body that is partially or wholly receivable in an oral cavity. The body includes a soluble-fiber matrix and nicotine or a derivative thereof dispersed in the soluble-fiber matrix. A nicotine lozenge may include at least 40 weight percent of soluble fiber. Soluble fiber in a nicotine lozenge may include maltodextrin. The nicotine lozenge is adapted to release the nicotine or a derivative thereof from the body when the body is received within the oral cavity of an adult consumer and exposed to saliva. A method of making nicotine lozenges includes forming a molten mixture of at least 40 weight percent soluble fiber, nicotine, and less than 15 weight percent water while maintaining a mixture temperature of less than 150° C. and portioning the molten mixture into a plurality of nicotine lozenges. The ingredients can be mixed to form the molten mixture in an extruder.

公开(公告)号：US20190175582A1

公开(公告)日：2019-06-13

申请号：US16214490

申请日：2018-12-10

Applicant: Altria Client Services LLC

Inventor： Feng GAO ,  Frank Scott Atchley ,  Gregory James Griscik ,  Christopher Joseph Dinovi ,  Phillip M. Hulan ,  Diane L. Gee ,  Jason Flora ,  Shuzhong Zhuang

IPC: A61K31/465 ,  B29C48/00 ,  A24B15/16 ,  A24B15/30 ,  A24B15/14 ,  A61K9/00 ,  A61K9/20 ,  A61K36/81 ,  A61K45/06 ,  A61J3/10

CPC classification number: A61K31/465 ,  A24B15/14 ,  A24B15/16 ,  A24B15/30 ,  A24B15/308 ,  A61J3/10 ,  A61K9/0053 ,  A61K9/2013 ,  A61K9/2031 ,  A61K9/205 ,  A61K9/2054 ,  A61K9/2095 ,  A61K36/81 ,  A61K45/06 ,  B29C48/0011 ,  B29C48/0022 ,  B29C48/022 ,  B29K2075/00 ,  B29K2401/00 ,  B29K2407/00 ,  B29L2031/753

Abstract: An oral product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-stable polymer matrix, cellulosic fibers embedded in the mouth-stable polymer matrix, and a mouth-soluble binder dispersed in the mouth-stable polymer matrix.

公开(公告)号：US20250009733A1

公开(公告)日：2025-01-09

申请号：US18897538

申请日：2024-09-26

Applicant: Altria Client Services LLC

Inventor： Feng GAO ,  Frank Scott ATCHLEY ,  Gregory James GRISCIK ,  Christopher Joseph DINOVI ,  Phillip M. HULAN ,  Diane L. GEE ,  Jason FLORA ,  Shuzhong ZHUANG

IPC: A61K31/465 ,  A24B15/14 ,  A24B15/16 ,  A24B15/30 ,  A61J3/10 ,  A61K9/00 ,  A61K9/20 ,  A61K36/81 ,  A61K45/06 ,  B29C48/00 ,  B29K75/00 ,  B29K401/00 ,  B29K407/00 ,  B29L31/00

Abstract: An oral product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-stable polymer matrix, cellulosic fibers embedded in the mouth-stable polymer matrix, and a mouth-soluble binder dispersed in the mouth-stable polymer matrix.

公开(公告)号：US20240189297A1

公开(公告)日：2024-06-13

申请号：US18581955

申请日：2024-02-20

Applicant: Altria Client Services LLC

Inventor： Feng GAO ,  David PHILLIPS ,  Pauline MARCQ ,  Anthony KIEU ,  Benjamin L. RAGLAND

IPC: A61K31/465 ,  A23G4/06 ,  A23G4/08 ,  A23G4/12 ,  A61K9/68 ,  A61K45/06 ,  A61K47/14 ,  A61K47/32

CPC classification number: A61K31/465 ,  A23G4/066 ,  A23G4/08 ,  A23G4/126 ,  A61K9/0058 ,  A61K45/06 ,  A61K47/14 ,  A61K47/32 ,  A23V2002/00

Abstract: At least one example embodiment relates to a chewing gum. In at least one example embodiment, the chewing gum comprises a gum base polymer and oil. The gum base polymer includes polyvinyl acetate (PVA) in an amount ranging from 35 weight percent to 55 weight percent of the chewing gum. The oil is present in an amount greater than 8 weight percent of the chewing gum. The oil includes a triglyceride, triacetin, and nicotine or a nicotine derivative. The triglyceride is present in an amount greater than or equal to 5 weight percent of the chewing gum. At least one example embodiment relates to a method of preparing a controlled-release nicotine chewing gum.

公开(公告)号：US20240188621A1

公开(公告)日：2024-06-13

申请号：US18582900

申请日：2024-02-21

Applicant: Altria Client Services LLC

Inventor： Feng GAO ,  Shuzhong ZHUANG ,  Diane GEE

IPC: A24B15/16 ,  A23G4/06 ,  A24B13/00 ,  A24B15/28 ,  A24B15/30 ,  C07D401/04

CPC classification number: A24B15/16 ,  A23G4/06 ,  A24B13/00 ,  A24B15/285 ,  A24B15/303 ,  C07D401/04

Abstract: This document provides methods and systems for stabilizing nicotine and incorporating nicotine into one or more oral products. This document also provides oral products. Nicotine can be stabilized by mixing liquid nicotine with cellulosic fiber such that the liquid nicotine absorbs into pores of the cellulosic fiber to form a cellulosic fiber-nicotine mixture. In some cases, a cellulosic fiber-nicotine mixture can be combined with one or more binders and molded into an oral product.

公开(公告)号：US20230240359A1

公开(公告)日：2023-08-03

申请号：US17586959

申请日：2022-01-28

Applicant: Altria Client Services LLC

Inventor： Baiwei CHEN ,  Feng GAO ,  Shannon M. BLACK ,  Shaoyong YU ,  Shuzhong ZHUANG ,  Benjamin L. RAGLAND ,  Rebecca M. GRAY ,  Fadi ALDEEK

IPC: A24F23/02 ,  A61K31/465 ,  A61K9/00 ,  A24B15/30

CPC classification number: A24F23/02 ,  A61K31/465 ,  A61K9/009 ,  A24B15/30

Abstract: An oral pouch product includes a wrapper and a filling material. The wrapper defines a cavity. The filling material is in the cavity. The filling material includes a dry mixture and a liquid mixture. The dry mixture includes a cellulosic material and a water-soluble filler. The liquid mixture includes an oil and liquid nicotine. The oil includes a triglyceride, a diglyceride, a monoglyceride, or any combination thereof. The liquid nicotine is dissolved in the oil. The filling material is free of water or includes water in an amount less than or equal to 5 weight percent.

公开(公告)号：US20230121049A1

公开(公告)日：2023-04-20

申请号：US18066730

申请日：2022-12-15

Applicant: Altria Client Services LLC

Inventor： Feng GAO ,  Diane L. GEE ,  Shuzhong ZHUANG ,  Phillip M. HULAN ,  William J. BURKE ,  Gerd KOBAL

IPC: A61K9/20 ,  A23G3/38 ,  A23G3/42 ,  A61K8/73 ,  A61Q11/00 ,  A23G3/34

Abstract: A soluble fiber lozenge in includes a body that is partially or wholly receivable in an oral cavity. The body includes a soluble-fiber matrix and one or more additives in the soluble-fiber matrix. A soluble fiber lozenge provided herein includes at least 40 weight percent of soluble fiber. Soluble fiber in soluble fiber lozenge can include maltodextrin. The soluble fiber lozenge is adapted to release one or more additives from the body when the body is received within the oral cavity of a consumer and exposed to saliva. A method of making soluble fiber lozenges includes forming a molten mixture of at least 40 weight percent soluble fiber, one or more additives, and less than 15 weight percent water while maintaining a mixture temperature of less than 200° C. and portioning the molten mixture into a plurality of soluble fiber lozenges.

公开(公告)号：US20210345657A1

公开(公告)日：2021-11-11

申请号：US17380255

申请日：2021-07-20

Applicant: Altria Client Services LLC

Inventor： Feng GAO ,  Shuzhong ZHUANG ,  Diane L. GEE

IPC: A24B15/16 ,  A23G4/06 ,  C07D401/04 ,  A24B15/28 ,  A24B15/30 ,  A24B13/00

Abstract: This document provides methods and systems for stabilizing nicotine and incorporating nicotine into one or more oral products. This document also provides oral products. Nicotine can be stabilized by mixing liquid nicotine with cellulosic fiber such that the liquid nicotine absorbs into pores of the cellulosic fiber to form a cellulosic fiber-nicotine mixture. In some cases, a cellulosic fiber-nicotine mixture can be combined with one or more binders and molded into an oral product.