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公开(公告)号：US20220403402A1
公开(公告)日：2022-12-22
申请号：US17830072
申请日：2022-06-01
Applicant: Altria Client Services LLC
Inventor： Chengalrayan KUDITHIPUDI , Dongmei Xu , James Strickland , Yanxin Shen
Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), increase phenylalanine, or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
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公开(公告)号：US20220267787A1
公开(公告)日：2022-08-25
申请号：US17683227
申请日：2022-02-28
Applicant: ALTRIA CLIENT SERVICES LLC
Inventor： Chengalrayan Kudiputhi , Alec J. Hayes , Robert Frank Hart , Yanxin Shen , Jesse Frederick , Dongmei Xu
Abstract: Provided herein are genetic markers and a coding sequence associated with a low- or ultra-low anatabine trait in tobacco.
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13.发明授权公开(公告)号：US10813318B2
公开(公告)日：2020-10-27
申请号：US15914033
申请日：2018-03-07
Applicant: ALTRIA CLIENT SERVICES LLC
Inventor： Jesse Frederick , Yanxin Shen , Dongmei Xu , Ujwala Warek , James Arthur Strickland
IPC: A01H5/12 , C07K14/415 , A01H1/02 , A24B15/20 , C12N15/82 , A01H1/06 , C12Q1/6895 , G01N33/00
Abstract: This disclosure provides a number of sequences involved in the transport of alkaloids from the root to the leaf in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences, and tobacco products made from such plants.
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公开(公告)号：US20190241900A1
公开(公告)日：2019-08-08
申请号：US16228035
申请日：2018-12-20
Applicant: Altria Client Services LLC
Inventor： Chengalrayan Kudithipudi , Raja Payyavula , Dong Qi , Yanxin Shen
IPC: C12N15/82
CPC classification number: C12N15/825 , C12N15/8262
Abstract: The present specification provides for, and includes recombinant polynucleotides that encode plant-native, callus-preferred promoters operably linked to a coding region for a visual marker gene. The present specification also provides for, and includes plants comprising the recombinant nucleotides, methods to select callus comprising the disclosed recombinant nucleotides, and methods to create plants comprising the recombinant nucleotides.
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15.发明申请公开(公告)号：US20180199532A1
公开(公告)日：2018-07-19
申请号：US15914033
申请日：2018-03-07
Applicant: ALTRIA CLIENT SERVICES LLC
Inventor： Jesse Frederick , Yanxin Shen , Dongmei Xu , Ujwala Warek , James Arthur Strickland
IPC: A01H5/12 , G01N33/00 , A01H1/02 , A01H1/06 , A24B15/20 , C12Q1/6895 , C12N15/82 , C07K14/415
Abstract: This disclosure provides a number of sequences involved in the transport of alkaloids from the root to the leaf in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences, and tobacco products made from such plants.
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Patent Agency Ranking
公开(公告)号：US12203082B2
公开(公告)日：2025-01-21
申请号：US17551565
申请日：2021-12-15
Applicant: ALTRIA CLIENT SERVICES LLC
Inventor： Chengalrayan Kudithipudi , Yanxin Shen , Dongmei Xu , Jesse Frederick , Jaemo Yang
IPC: C12N15/82 , C07K14/415
Abstract: This disclosure provides a number of sequences involved in axillary bud growth in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences or transgenes of such sequences, and tobacco products made from tobacco leaf harvested from such plants.
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17.发明授权公开(公告)号：US11807860B2
公开(公告)日：2023-11-07
申请号：US16908891
申请日：2020-06-23
Applicant: Altria Client Services LLC
Inventor： Dongmei Xu , Chengalrayan Kudithipudi , Yanxin Shen , Jaemo Yang , Jesse Frederick , James Strickland
IPC: C12N15/82 , C07K14/415 , A24B13/00 , A24B15/10
CPC classification number: C12N15/8261 , A24B13/00 , A24B15/10 , C07K14/415 , C12N15/827 , Y02A40/146
Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
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公开(公告)号：US11767535B2
公开(公告)日：2023-09-26
申请号：US17684078
申请日：2022-03-01
Applicant: Altria Client Services LLC
Inventor： Chengalrayan Kudithipudi , Jaemo Yang , Yanxin Shen , Dongmei Xu , Ujwala Warek , James Strickland , Jesse Frederick
IPC: C12N15/82
CPC classification number: C12N15/8235 , C12N15/827
Abstract: The present disclosure provides the identification of promoters that are preferentially active in tobacco axillary buds. Also provided are tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing tobacco plants comprising reduced or no sucker growth.
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公开(公告)号：US11299743B2
公开(公告)日：2022-04-12
申请号：US16825394
申请日：2020-03-20
Applicant: ALTRIA CLIENT SERVICES LLC
Inventor： Chengalrayan Kudithipudi , Alec J. Hayes , Robert Frank Hart, III , Yanxin Shen , Jesse Frederick , Dongmei Xu
Abstract: Provided herein are genetic markers and a coding sequence associated with a low- or ultra-low anatabine trait in tobacco.
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公开(公告)号：US11236349B2
公开(公告)日：2022-02-01
申请号：US16589783
申请日：2019-10-01
Applicant: ALTRIA CLIENT SERVICES LLC
Inventor： Chengalrayan Kudithipudi , Yanxin Shen , Dongmei Xu , Jesse Frederick , Jaemo Yang
IPC: C12N15/82 , C07K14/415
Abstract: This disclosure provides a number of sequences involved in axillary bud growth in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences or transgenes of such sequences, and tobacco products made from tobacco leaf harvested from such plants.
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