公开(公告)号：US20110303219A1

公开(公告)日：2011-12-15

申请号：US13216529

申请日：2011-08-24

Applicant: Michael S. Smith ,  Greg Voss ,  Peter Bliss ,  Scott Halperin

Inventor： Michael S. Smith ,  Greg Voss ,  Peter Bliss ,  Scott Halperin

IPC: A61M16/12 ,  A61M11/00

CPC classification number: A61M16/12 ,  A61M16/08 ,  A61M16/107 ,  A61M16/204 ,  A61M16/209 ,  A61M2016/0027 ,  A61M2016/003 ,  A61M2202/0208 ,  A61M2205/70

Abstract: A gas blender with auxiliary mixed gas outlet for mixing a primary gas, generally air, and a secondary gas, generally oxygen, to obtain a mixed gas having several controlled characteristics. The gas blender may be incorporated into a Continuous Positive Airway Pressure (CPAP) device. The gas blender controls the mixing to produce the mixed gas having a predetermined mixture setpoint, generally an oxygen percentage, and a predetermined control setpoint, generally a pressure setpoint or flow rate setpoint. The gas blender provides an auxiliary mixed gas source for use by an auxiliary piece of equipment such as a nebulizer or resuscitation bag. The gas blender includes a primary gas inlet passageway, a secondary gas inlet passageway, a gas mixing apparatus, a mixed gas distribution passageway with an auxiliary mixed gas outlet, a gas sensor, a delivery sensor, a mixed gas delivery control valve, a mixed gas controlled passageway, and a controller.

Abstract translation: 一种具有辅助混合气体出口的气体混合器，用于混合初级气体（通常为空气）和二次气体（通常为氧气），以获得具有几个受控特性的混合气体。 气体混合器可以并入连续气道正压通气（CPAP）装置中。 气体混合器控制混合以产生具有预定混合物设定点（通常为氧气百分比）和预定控制设定点（通常为压力设定点或流量设定点）的混合气体。 气体混合器提供辅助混合气体源，用于辅助设备如雾化器或复苏袋。 气体混合器包括主气体入口通道，二次气体入口通道，气体混合设备，具有辅助混合气体出口的混合气体分配通道，气体传感器，输送传感器，混合气体输送控制阀，混合 气体控制通道和控制器。

公开(公告)号：US20100239611A1

公开(公告)日：2010-09-23

申请号：US12587955

申请日：2009-10-15

Applicant: Sylvia van Drunen Littel-van den Hurk ,  Volker Gerdts ,  Andrew Potter ,  Lorne Babiuk ,  Robert Hancock ,  Scott Halperin ,  Jennifer Kovacs-Nolan ,  George Mutwiri ,  Song Lee ,  Mi-Na Kweon ,  Jason Kindrachuk ,  Melissa Elliot

Inventor： Sylvia van Drunen Littel-van den Hurk ,  Volker Gerdts ,  Andrew Potter ,  Lorne Babiuk ,  Robert Hancock ,  Scott Halperin ,  Jennifer Kovacs-Nolan ,  George Mutwiri ,  Song Lee ,  Mi-Na Kweon ,  Jason Kindrachuk ,  Melissa Elliot

IPC: A61K39/155 ,  A61K39/39 ,  C07K7/08 ,  A61K39/35 ,  A61K39/10 ,  A61P31/12 ,  A61P31/04 ,  A61P31/10 ,  A61P33/00

CPC classification number: A61K39/39 ,  A61K39/099 ,  A61K39/12 ,  A61K39/155 ,  A61K45/06 ,  A61K47/30 ,  A61K2039/55516 ,  A61K2039/55561 ,  A61K2039/6093 ,  C07K7/08 ,  C12N2760/18534

Abstract: Methods and compositions for enhancing an immune response to a selected antigen are described. The methods are useful for the treatment and prevention of microbial infections, such as infections caused by bacteria, viruses, fungi and parasites. The methods and compositions include host defense peptides, polyphosphazenes and immunostimulatory sequences to enhance the immune response to a coadministered antigen.

Abstract translation: 描述了增强对所选抗原的免疫应答的方法和组合物。 该方法可用于治疗和预防微生物感染，例如由细菌，病毒，真菌和寄生虫引起的感染。 方法和组合物包括宿主防御肽，聚磷腈和免疫刺激序列，以增强对共同施用的抗原的免疫应答。

公开(公告)号：US20060230939A1

公开(公告)日：2006-10-19

申请号：US11099722

申请日：2005-04-05

Applicant: Peter Bliss ,  Charles Atlas ,  Scott Halperin

Inventor： Peter Bliss ,  Charles Atlas ,  Scott Halperin

IPC: B01D53/02

CPC classification number: B01D53/0446 ,  B01D53/0415 ,  B01D53/053 ,  B01D2253/108 ,  B01D2256/12 ,  B01D2257/102 ,  B01D2257/80 ,  B01D2259/40003 ,  B01D2259/40009 ,  B01D2259/402 ,  B01D2259/4146 ,  B01D2259/4533 ,  B01D2259/4541

Abstract: A portable oxygen concentrator includes a pair of sieve beds having first and second ends, a compressor for delivering air to the first ends of the sieve beds, a reservoir communicating with the second ends of the sieve beds, and an air manifold attached to the first ends of the sieve beds. The air manifold includes passages therein communicating with the compressor and the first ends of the sieve beds. A set of valves is coupled to the air manifold, and a controller is coupled to the valves for selectively opening and closing the valves to alternately charge and purge the sieve beds to deliver concentrated oxygen into the reservoir. An oxygen delivery manifold communicates with the second ends of the sieve beds for delivering oxygen from the reservoir to a user. Pressure sensors may be provided in the reservoir and/or delivery line for controlling operation of the controller.

公开(公告)号：US08006692B2

公开(公告)日：2011-08-30

申请号：US11292641

申请日：2005-12-02

Applicant: Michael S. Smith ,  Greg Voss ,  Peter Bliss ,  Scott Halperin

Inventor： Michael S. Smith ,  Greg Voss ,  Peter Bliss ,  Scott Halperin

IPC: A61M15/00

CPC classification number: A61M16/12 ,  A61M16/08 ,  A61M16/107 ,  A61M16/204 ,  A61M16/209 ,  A61M2016/0027 ,  A61M2016/003 ,  A61M2202/0208 ,  A61M2205/70

Abstract: A gas blender with auxiliary mixed gas outlet for mixing a primary gas, generally air, and a secondary gas, generally oxygen, to obtain a mixed gas having several controlled characteristics. The gas blender may be incorporated into a Continuous Positive Airway Pressure (CPAP) device. The gas blender controls the mixing to produce the mixed gas having a predetermined mixture setpoint, generally an oxygen percentage, and a predetermined control setpoint, generally a pressure setpoint or flow rate setpoint. The gas blender provides an auxiliary mixed gas source for use by an auxiliary piece of equipment such as a nebulizer or resuscitation bag. The gas blender includes a primary gas inlet passageway, a secondary gas inlet passageway, a gas mixing apparatus, a mixed gas distribution passageway with an auxiliary mixed gas outlet, a gas sensor, a delivery sensor, a mixed gas delivery control valve, a mixed gas controlled passageway, and a controller.

Abstract translation: 一种具有辅助混合气体出口的气体混合器，用于混合初级气体（通常为空气）和二次气体（通常为氧气），以获得具有几个受控特性的混合气体。 气体混合器可以并入连续气道正压通气（CPAP）装置中。 气体混合器控制混合以产生具有预定混合物设定点（通常为氧气百分比）和预定控制设定点（通常为压力设定点或流量设定点）的混合气体。 气体混合器提供辅助混合气体源，用于辅助设备如雾化器或复苏袋。 气体混合器包括主气体入口通道，二次气体入口通道，气体混合设备，具有辅助混合气体出口的混合气体分配通道，气体传感器，输送传感器，混合气体输送控制阀，混合 气体控制通道和控制器。

公开(公告)号：US20080053310A1

公开(公告)日：2008-03-06

申请号：US11731482

申请日：2007-03-30

Applicant: Peter Bliss ,  Charles Atlas ,  Scott Halperin

Inventor： Peter Bliss ,  Charles Atlas ,  Scott Halperin

IPC: B01D53/02 ,  F01B1/06 ,  F04B1/04

CPC classification number: B01D53/0407 ,  A61M16/0051 ,  A61M16/026 ,  A61M16/10 ,  A61M16/101 ,  A61M16/107 ,  A61M2016/1025 ,  A61M2202/0208 ,  A61M2202/03 ,  B01D53/0446 ,  B01D53/0454 ,  B01D53/047 ,  B01D2253/108 ,  B01D2256/12 ,  B01D2257/102 ,  B01D2259/4533 ,  B01D2259/455 ,  F04B43/02 ,  F04B43/021 ,  A61M2202/0007

Abstract: A compressor suitable for use in a portable oxygen concentrator. In one exemplary embodiment, the compressor includes a crankshaft rotatable about a central axis and a plurality of diaphragm assemblies spaced apart around the central axis generally within a plane. The diaphragm assemblies include diaphragms movably mounted to respective housings to at least partially define chambers. A plurality of rods extend between respective diaphragms and the crankshaft. The rods are coupled to the crankshaft such that the rods are offset axially from one another along the central axis and are coupled to the diaphragms for cyclically increasing and decreasing pressure within the chambers as the crankshaft rotates about the central axis.

Abstract translation: 一种适用于便携式氧气浓缩器的压缩机。 在一个示例性实施例中，压缩机包括可围绕中心轴线旋转的曲轴和大致在平面内围绕中心轴线间隔开的多个隔膜组件。 膜片组件包括可移动地安装到相应壳体以至少部分地限定腔室的膜片。 多个杆在相应的隔膜和曲轴之间延伸。 杆联接到曲轴，使得杆沿着中心轴线彼此轴向偏移，并且当曲轴围绕中心轴线旋转时，联接到隔膜以循环地增加和减小腔室内的压力。

公开(公告)号：US20060230929A1

公开(公告)日：2006-10-19

申请号：US11099830

申请日：2005-04-05

Applicant: Peter Bliss ,  Charles Atlas ,  Scott Halperin

Inventor： Peter Bliss ,  Charles Atlas ,  Scott Halperin

IPC: B01D53/02

CPC classification number: B01D53/0407 ,  B01D53/0446 ,  B01D53/0454 ,  B01D53/047 ,  B01D53/053 ,  B01D2253/108 ,  B01D2256/12 ,  B01D2257/102 ,  B01D2259/40009 ,  B01D2259/402 ,  B01D2259/4533 ,  B01D2259/4541

Abstract: A portable oxygen concentrator includes a pair of sieve beds having first and second ends, a compressor for delivering air to the first ends of the sieve beds, a reservoir communicating with the second ends of the sieve beds, and an air manifold attached to the first ends of the sieve beds. The air manifold includes passages therein communicating with the compressor and the first ends of the sieve beds. A set of valves is coupled to the air manifold, and a controller is coupled to the valves for selectively opening and closing the valves to alternately charge and purge the sieve beds to deliver concentrated oxygen into the reservoir. An oxygen delivery manifold communicates with the second ends of the sieve beds for delivering oxygen from the reservoir to a user. Pressure sensors may be provided in the reservoir and/or delivery line for controlling operation of the controller.