公开(公告)号：US12097329B2

公开(公告)日：2024-09-24

申请号：US17289359

申请日：2019-10-22

Applicant: Chiesi Farmaceutici S.p.A.

Inventor： Ruben Agazzi ,  Benedetta Campolo ,  Nicolò Dallacasa ,  Edoardo Davico ,  Chantal Erika Speziali

IPC: A61M16/08 ,  A61M15/00 ,  A61M16/00 ,  A61M16/04 ,  A61M16/10 ,  A61M16/20

CPC classification number: A61M16/0816 ,  A61M16/0883 ,  A61M16/10 ,  A61M15/0091 ,  A61M16/0057 ,  A61M16/04 ,  A61M16/0833 ,  A61M16/204 ,  A61M2202/064

Abstract: An apparatus to administer drugs to mechanically ventilated patients includes a mechanical ventilator, an artificial airway to be associated to a patient and a ventilation circuit connecting the mechanical ventilator to the artificial airway. The ventilation circuit includes: an inspiratory line, a dry powder inhaler disposed in line on the inspiratory line and a connector operatively connected to the dry powder inhaler and to the inspiratory line. The connector includes: a first duct facing an outlet port of the dry powder inhaler and connected or configured to be connected to a tube section of the inspiratory line placed downstream the dry powder inhaler; a second duct facing an air inlet port of the dry powder inhaler and connected or configured to be connected to a tube section of the inspiratory line placed upstream the dry powder inhaler.

公开(公告)号：US20240269421A1

公开(公告)日：2024-08-15

申请号：US18023288

申请日：2022-09-02

Applicant: Ryan Redford

Inventor： Ryan Redford

IPC: A61M16/20 ,  A61M16/00 ,  A61M16/04 ,  A61M16/06 ,  A61M16/10

CPC classification number: A61M16/204 ,  A61M16/0063 ,  A61M16/0066 ,  A61M16/022 ,  A61M16/0461 ,  A61M16/0465 ,  A61M16/06 ,  A61M16/1045 ,  A61M2016/0027 ,  A61M2016/0039 ,  A61M2016/0042 ,  A61M2202/0208 ,  A61M2205/3303 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3341 ,  A61M2205/36 ,  A61M2230/005 ,  A61M2230/40

Abstract: A respiratory ventilators system having an inlet configured to be connected to a pressurized air or gas source; an outlet configured to be connected to a patient interface; a valve in-line between the inlet and the outlet; and a control unit configured to control the valve for controlling flow of pressurized air or gas from the source to the patient, wherein the valve includes an air or gas reservoir or accumulator incorporated into the valve body.

公开(公告)号：US11998689B2

公开(公告)日：2024-06-04

申请号：US17525349

申请日：2021-11-12

Applicant: Mallinckrodt Pharmaceuticals Ireland Limited

Inventor： Jaron M. Acker ,  John C. Falligant ,  Jeff Milsap ,  Robin Roehl ,  Jeffrey Schmidt ,  Craig R. Tolmie

IPC: A61M16/00 ,  A61M16/10 ,  A61M16/12 ,  A61M16/20 ,  B63C11/02 ,  G01F22/02 ,  A61M16/08

CPC classification number: A61M16/0051 ,  A61M16/024 ,  A61M16/1005 ,  A61M16/12 ,  A61M16/122 ,  A61M16/125 ,  A61M16/201 ,  A61M16/202 ,  A61M16/204 ,  B63C11/02 ,  G01F22/02 ,  A61M2016/0027 ,  A61M2016/0039 ,  A61M16/085 ,  A61M2016/102 ,  A61M16/208 ,  A61M2202/0275 ,  A61M2205/14 ,  A61M2205/16 ,  A61M2205/17 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3379 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/60 ,  A61M2205/6018 ,  A61M2205/6072 ,  A61M2205/8206 ,  F17C2250/00

Abstract: Therapy gas delivery systems that provide run-time-to-empty information to a user of the system and methods for administering therapeutic gas to a patient. The therapeutic gas delivery system may include a gas pressure sensor attachable to a therapeutic gas source that communicates therapeutic gas pressure data to a therapeutic gas delivery system controller, a gas temperature sensor positioned to measure gas temperature in the therapeutic gas source that communicates therapeutic gas temperature data to the therapeutic gas delivery system controller, at least one flow controller that communicates therapeutic gas flow rate data to the therapeutic gas delivery system controller, at least one flow sensor that communicates flow rate data to the therapeutic gas delivery system controller, and at least one display that communicates run-time-to-empty to a user of the therapeutic gas delivery system. The therapeutic gas delivery system controller of the system includes a processor that executes an algorithm to calculate the run-time-to-empty from the data received from the gas pressure sensor, temperature sensor, flow controller and flow sensor, and directs the result to the display.

公开(公告)号：US11975139B2

公开(公告)日：2024-05-07

申请号：US17935055

申请日：2022-09-23

Applicant: Third Pole, Inc.

Inventor： Christopher Miles ,  Frank Heirtzler ,  Gregory W. Hall ,  Sweta Patel ,  Wolfgang Scholz

IPC: A61M15/00 ,  A61M11/04 ,  A61M16/00 ,  A61M16/10 ,  A61M16/12 ,  A61M16/14 ,  A61M16/20

CPC classification number: A61M15/0003 ,  A61M15/0021 ,  A61M15/0086 ,  A61M16/0051 ,  A61M16/022 ,  A61M16/10 ,  A61M16/107 ,  A61M16/12 ,  A61M16/125 ,  A61M16/14 ,  A61M16/204 ,  A61M11/042 ,  A61M15/0085 ,  A61M15/009 ,  A61M2016/0018 ,  A61M16/109 ,  A61M16/122 ,  A61M2202/0275 ,  A61M2205/3334

Abstract: Systems and methods are provided for delivering one or more drugs. In some embodiments, a drug delivery system includes a housing having a distal end with an inlet through which an inspiratory flow of air passes into the housing, a proximal end having a patient interface attached thereto, the patient interface being configured to interface with a user, and an inspiratory flow pathway extending from the distal end to the proximal end of the housing. A nitric oxide (NO) source is positioned within the housing and is configured to deliver NO-containing gas to the patient interface. A secondary drug source is positioned within the housing and is configured to deliver a secondary drug to the patient interface. A controller is configured to control an amount of NO-containing gas and an amount of the secondary drug delivered using a control scheme.

公开(公告)号：US20240042161A1

公开(公告)日：2024-02-08

申请号：US18245936

申请日：2021-09-17

Applicant: Carnegie Mellon University ,  University of Pittsburgh - Of the Commonwealth System of Higher Education

Inventor： Lu Li ,  Michael B. Schwerin ,  Howie Choset ,  Keith E. Cook ,  Jason Rose

IPC: A61M16/20 ,  A61M16/10 ,  G06N20/00

CPC classification number: A61M16/204 ,  A61M16/1005 ,  A61M16/205 ,  G06N20/00 ,  A61M2205/3372 ,  A61M2016/0027

Abstract: Provided is a system for operating a ventilator. The system includes a motorized proportional valve actuator including a stepper motor and an actuator. The actuator is connected to the stepper motor and configured to output pressurized air by controlling a pressure on a valve diaphragm. A conduit provides for fluid communication of the pressurized air to a breathing apparatus. A sensor arrangement is in fluid communication with the conduit between the at least one motorized proportional valve actuator and the breathing apparatus. The sensor arrangement includes: (i) an intake manifold configured to output a restricted flow of air from the pressurized air transported in the conduit, and (ii) a sensor device in fluid communication with an outlet of the intake manifold, the sensor device configured to measure an air pressure of the conduit based on the restricted flow of air.

公开(公告)号：US11878123B2

公开(公告)日：2024-01-23

申请号：US17902524

申请日：2022-09-02

Applicant: ResMed Pty Ltd

Inventor： Peter John Sweeney ,  Adam Vivian Benjafield ,  Steven Paul Farrugia ,  Dieter Heidmann ,  Glenn Richards ,  Paul Jan Klasek

IPC: A61M16/16 ,  A61M16/00 ,  A61M16/06 ,  A61M16/10 ,  A61M16/20 ,  A61M16/08

CPC classification number: A61M16/16 ,  A61M16/0069 ,  A61M16/024 ,  A61M16/0688 ,  A61M16/1095 ,  A61M16/161 ,  A61M16/204 ,  A61M16/0066 ,  A61M16/0666 ,  A61M16/0825 ,  A61M16/107 ,  A61M2016/0021 ,  A61M2016/0027 ,  A61M2016/0039 ,  A61M2202/0208 ,  A61M2205/18 ,  A61M2205/3368 ,  A61M2205/502 ,  A61M2205/8206 ,  A61M2205/8237

Abstract: A device (102) provides respiratory treatment for SDB (including mild OSA) and other respiratory conditions. A flow generator warms and humidifies gas at controlled flow levels. For example, the device (102) delivers breathable gas to the upper airway at flow rates of about 10-35 Liters/minute. Levels of flow rate, temperature and/or humidification of the device may be automatically adjusted in response to the detection of SDB events. The device may also automatically deliver adjustments of any of the levels in accordance with detected phases of respiratory cycles. In some embodiments, the device automatically delivers distinct levels to either of the nares based on independent control of flow to each nare. A warm-up procedure controls temperature and humidity at a desired target during a ramp-up of flow to the set therapy level. A cool-down procedure controls temperature above the dewpoint to avoid condensation internal to the device and patient interface.

公开(公告)号：US11865255B2

公开(公告)日：2024-01-09

申请号：US17694563

申请日：2022-03-14

Applicant: Invent Medical Corporation

Inventor： Samuel M. Chang

IPC: A61M16/00 ,  A61M16/10 ,  A61M16/12 ,  A61M16/20

CPC classification number: A61M16/0066 ,  A61M16/0051 ,  A61M16/0057 ,  A61M16/026 ,  A61M16/1005 ,  A61M16/12 ,  A61M16/202 ,  A61M16/204 ,  A61M16/205 ,  A61M16/1055 ,  A61M16/208 ,  A61M2016/0027 ,  A61M2016/0036 ,  A61M2016/0039 ,  A61M2016/1025 ,  A61M2202/0208 ,  A61M2202/0241 ,  A61M2202/0266 ,  A61M2202/0291 ,  A61M2205/3331 ,  A61M2205/3355 ,  A61M2205/50 ,  A61M2205/7518 ,  A61M2230/04 ,  A61M2230/06 ,  A61M2230/10 ,  A61M2230/205 ,  A61M2230/30 ,  A61M2230/432 ,  A61M2230/50 ,  A61M2230/30 ,  A61M2230/005 ,  A61M2230/06 ,  A61M2230/005 ,  A61M2230/205 ,  A61M2230/005 ,  A61M2230/10 ,  A61M2230/005 ,  A61M2230/04 ,  A61M2230/005 ,  A61M2230/50 ,  A61M2230/005 ,  A61M2230/432 ,  A61M2230/005

Abstract: A ventilator is configured to supply a gas mixture to the lungs of a subject. The gas mixture comprises a first gas (e.g. oxygen) and a second gas (e.g. ambient air). The ventilator comprise a first gas inlet, a second gas inlet, flow modulator of the first gas, a flow modulator of the second gas, a junction configured to mix the first gas and the second gas, a patient interface configured to deliver the gas mixture to a subject, a pressure sensor, a plurality of flow sensors comprising at least a first flow sensor and a second flow sensor, and at least one controller configured for obtaining data from the pressure sensor and flow sensors and controlling the flow modulators to provide a gas mixture having a target pressure and a target oxygen content.

公开(公告)号：US11786693B2

公开(公告)日：2023-10-17

申请号：US16880741

申请日：2020-05-21

Applicant: Drägerwerk AG & Co. KGaA

Inventor： Hans-Ullrich Hansmann

IPC: A61M16/00 ,  A61M16/20

CPC classification number: A61M16/204 ,  A61M16/0057 ,  A61M16/205 ,  A61M2016/0027 ,  A61M2205/0294 ,  A61M2205/3341

Abstract: A device (1), for a ventilation system (100), includes an inhalation valve (10) with an inhalation opening (11) for flow (301) of breathing gas (300) into a pressure chamber (110) to provide breathing gas in the pressure chamber for ventilating a patient (200). A closing element (12) is arranged movably, to close the inhalation opening to flow in a closed position (320) and to at least partially release flow in an open position (310). A transmission device (13) is connected via a connection element (14) to the closing element, to hold the closing element in the closed position in a starting position of the transmission device, such that the inhalation valve is normally closed. A control pressure source (130) provides a control pressure (PS) in a control pressure chamber (15) for the transmission device to move the transmission device out of the starting position by the control pressure.

公开(公告)号：US20230270960A1

公开(公告)日：2023-08-31

申请号：US18109510

申请日：2023-02-14

Applicant: Mallinckrodt Pharmaceuticals Ireland Limited

Inventor： Jaron M. Acker ,  Jeff Milsap ,  Robin Roehl ,  Jeffrey Schmidt ,  Craig R. Tolmie

IPC: A61M16/00 ,  B63C11/02 ,  G01F22/02 ,  A61M16/20 ,  A61M16/12 ,  A61M16/10

CPC classification number: A61M16/0051 ,  B63C11/02 ,  G01F22/02 ,  A61M16/204 ,  A61M16/024 ,  A61M16/12 ,  A61M16/1005 ,  A61M16/122 ,  A61M16/125 ,  A61M16/201 ,  A61M16/202 ,  A61M16/208 ,  A61M2205/6072 ,  A61M16/085

Abstract: A therapeutic gas delivery system with at least one gas supply subsystem is disclosed. The at least one gas supply subsystem may include a gas source coupling configured to receive a therapeutic gas source and form a fluid flow connection with the therapeutic gas source, a therapeutic gas delivery system controller, and one or more display(s) configured to be in communication over a communication path with the therapeutic gas delivery system controller. The display may be configured to display a graphical, illustrative, or numerical indicator of one or more flow or system parameters.

公开(公告)号：US11717637B2

公开(公告)日：2023-08-08

申请号：US17743708

申请日：2022-05-13

Applicant: RESMED PARIS SAS

Inventor： Philippe Auguste Chalvignac ,  Arthur Kin-Wai Yee ,  David Creusot ,  Enrico Brambilla

IPC: A61M16/20 ,  A61M16/00 ,  A61M16/12

CPC classification number: A61M16/203 ,  A61M16/0051 ,  A61M16/0066 ,  A61M16/0069 ,  A61M16/12 ,  A61M16/20 ,  A61M16/201 ,  A61M16/204 ,  A61M16/205 ,  A61M16/206 ,  A61M16/207 ,  A61M16/024 ,  A61M16/202 ,  A61M2016/0015 ,  A61M2016/0027 ,  A61M2202/0208 ,  A61M2205/3331 ,  A61M2205/3365

Abstract: A breathable gas inlet control device permits flow regulation at the inlet of a flow generator for a respiratory treatment apparatus such as a ventilator or continuous positive airway pressure device. The device may implement a variable inlet aperture size based on flow conditions. In one embodiment, an inlet flow seal opens or closes the inlet to a blower in accordance with changes in pressure within a seal activation chamber near the seal. The seal may be formed by a flexible membrane. A controller selectively changes the pressure of the seal activation chamber by controlling a set of one or more flow control valves to selectively stop forward flow, prevent back flow or lock open the seal to permit either back flow or forward flow. The controller may set the flow control valves as a function of detected respiratory conditions based on data from pressure and/or flow sensors.