摘要:
A DMT signal conforming to a first DMT standard (e.g., the full-rate G.dmt standard based on 255 tones) is sampled at a sampling rate for the first DMT standard, filtered to attenuate a subset of the tones of the first DMT standard (e.g., all G.dmt tones above tone #127), and subsampled (e.g., 2:1) to provide a subsampled, filtered signal that can be further processed using components designed to operate under a second, different DMT standard (e.g., the half-rate G.lite standard based on 127 tones). As such, a conventional half-rate G.lite DMT transceiver can be modified (e.g., by changing the downstream sampling rate from 1.104 MHz to 2.208 MHz and adding an appropriate low-pass filter and decimator) for configuration in a full-rate G.dmt DMT system. The filtering and subsampling ensure that a downstream signal (even if it is a full-rate DMT initialization or synchronization signal containing tones above tone #127) can successfully be further processed using conventional half-rate DMT transceiver components, which are less complex and less expensive than those of full-rate DMT transceivers, thereby enabling the use of relatively inexpensive consumer personal equipment (CPE) in existing distributed full-rate DMT telecommunications systems.
摘要:
Described are compositions and methods useful for modulating the immune system of a subject. Also included are diagnostic methods for monitoring an immunologic condition. In particular the invention relates to antagonists of interferon proteins and associated methods of use as well as methods to develop neutralizing antibodies against IFN antagonists to treat viral infections.
摘要:
Recombinant poxviruses, such as vaccinia, are provided that comprises a segment comprised of (A) a first DNA sequence encoding a polypeptide that is foreign to poxvirus and (B) a poxvirus transcriptional regulatory sequence, wherein (i) said transcriptional regulatory sequence is adjacent to and exerts transcriptional control over said first DNA sequence and (ii) said segment is positioned within a nonessential genomic region of said recombinant poxvirus. Vaccines, carriers, cells, and media comprising recombinant poxviruses, and methods of immunization with recombinant poxviruses also are provided.