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公开(公告)号：US20160296323A1
公开(公告)日：2016-10-13
申请号：US15082382
申请日：2016-03-28
Applicant: Boston Scientific SciMed, Inc.
Inventor： David Robert Wulfman , Thomas A. Wrobel , Crystal Marie Anderson-Cunanan , Joseph Thomas Delaney, JR. , Patrick Willoughby , Mark W. Boden , Peter G. Edelman , Michael Eppihimer
CPC classification number: A61F2/2412 , A61F2/2415 , A61L27/16 , A61L27/18 , A61L27/34 , A61L27/52 , A61L2400/12 , A61L2420/02 , A61L2420/08 , A61L2430/20 , C08L71/02
Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.
Abstract translation: 假体心脏瓣膜小叶包括至少部分地嵌入聚合物基质中的多个电纺纤维。 多根纤维包括具有第一预定重量百分比的硬链段部分的第一聚异丁烯氨基甲酸酯共聚物，聚合物基质包括具有第二预定重量百分比的硬链段部分的第二聚异丁烯聚氨酯共聚物，其中第一预定重量平均值 硬段部分的百分比大于硬段部分的第二预定重量平均百分比。
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公开(公告)号：US10716671B2
公开(公告)日：2020-07-21
申请号：US15193794
申请日：2016-06-27
Applicant: Boston Scientific SciMed, Inc.
Inventor： Michael Eppihimer , Peter G. Edelman
IPC: A61F2/24
Abstract: A prosthetic heart leaflet includes a fiber-reinforced structure including a plurality of composite fibers. Each composite fiber includes a core fiber and a sheathing fiber disposed about the core fiber, wherein the core fiber or the sheathing fiber has a curvilinear shape.
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13.发明申请公开(公告)号：US20170014227A1
公开(公告)日：2017-01-19
申请号：US15205098
申请日：2016-07-08
Applicant: Boston Scientific SciMed, Inc.
Inventor： Mark W. Boden , Peter G. Edelman , Joseph Thomas Delaney, JR.
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/2415 , A61F2210/0076 , A61F2220/0016 , A61F2250/0028 , A61F2250/0029 , A61F2310/00011 , A61F2310/00179 , A61L27/20
Abstract: A prosthetic heart valve leaflet is composed of a self-reinforced composite (SRC) structure that includes a first layer. The first layer can include a first plurality of fused fibers composed of a first polymeric material in which each fiber is fused to at least one adjacent fiber by a reflowed fiber domain region.
Abstract translation: 假体心脏瓣膜小叶由包括第一层的自增强复合材料（SRC）结构组成。 第一层可以包括由第一聚合物材料组成的第一多个熔融纤维，其中每个纤维通过回流纤维畴区域与至少一个相邻纤维熔合。
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公开(公告)号：US20160296322A1
公开(公告)日：2016-10-13
申请号：US15082293
申请日：2016-03-28
Applicant: Boston Scientific SciMed, Inc.
Inventor： Peter G. Edelman , Mark W. Boden , Joseph Thomas Delaney, JR.
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2002/009 , A61F2310/00389 , A61L27/14 , C08L101/02
Abstract: A prosthetic heart valve includes a plurality of synthetic polymeric leaflets. Each leaflet has a base polymer and a polymer coating at least partially disposed over the base polymer, wherein the polymer coating includes polymerized units of a monomer comprising a zwitterionic group when the polymer coating is exposed to an aqueous environment at a pH of about 7.4
Abstract translation: 假体心脏瓣膜包括多个合成的聚合单张。 每个小叶具有至少部分地设置在基础聚合物上的基础聚合物和聚合物涂层，其中当聚合物涂层暴露于约7.4的pH的水性环境时，聚合物涂层包括包含两性离子基团的单体的聚合单元
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公开(公告)号：US10426609B2
公开(公告)日：2019-10-01
申请号：US15082239
申请日：2016-03-28
Applicant: Boston Scientific SciMed, Inc.
Inventor： Peter G. Edelman , Joseph Thomas Delaney, Jr.
Abstract: A prosthetic heart valve includes a composite material that has a first plurality of fibers embedded in a polymer matrix. Each fiber can have a first extending direction and a plurality of undulations.
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Patent Agency Ranking
公开(公告)号：US10413403B2
公开(公告)日：2019-09-17
申请号：US15205098
申请日：2016-07-08
Applicant: Boston Scientific SciMed, Inc.
Inventor： Mark W. Boden , Peter G. Edelman , Joseph Thomas Delaney, Jr.
Abstract: A prosthetic heart valve leaflet is composed of a self-reinforced composite (SRC) structure that includes a first layer. The first layer can include a first plurality of fused fibers composed of a first polymeric material in which each fiber is fused to at least one adjacent fiber by a reflowed fiber domain region.
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公开(公告)号：US20190262131A1
公开(公告)日：2019-08-29
申请号：US16413104
申请日：2019-05-15
Applicant: Boston Scientific Scimed, Inc.
Inventor： David Robert Wulfman , Thomas A. Wrobel , Crystal Marie Anderson-Cunanan , Joseph Thomas Delaney, JR. , Patrick Willoughby , Mark W. Boden , Peter G. Edelman , Michael Eppihimer
Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.
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公开(公告)号：US10314696B2
公开(公告)日：2019-06-11
申请号：US15082382
申请日：2016-03-28
Applicant: Boston Scientific SciMed, Inc.
Inventor： David Robert Wulfman , Thomas A. Wrobel , Crystal Marie Anderson-Cunanan , Joseph Thomas Delaney, Jr. , Patrick Willoughby , Mark W. Boden , Peter G. Edelman , Michael Eppihimer
Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.
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公开(公告)号：US20170000610A1
公开(公告)日：2017-01-05
申请号：US15193794
申请日：2016-06-27
Applicant: Boston Scientific SciMed, Inc.
Inventor： Michael Eppihimer , Peter G. Edelman
IPC: A61F2/24
Abstract: A prosthetic heart leaflet includes a fiber-reinforced structure including a plurality of composite fibers. Each composite fiber includes a core fiber and a sheathing fiber disposed about the core fiber, wherein the core fiber or the sheathing fiber has a curvilinear shape.
Abstract translation: 假体心脏小叶包括包括多个复合纤维的纤维增强结构。 每个复合纤维包括芯纤维和围绕芯纤维布置的护套纤维，其中芯纤维或护套纤维具有曲线形状。
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公开(公告)号：US20150335321A1
公开(公告)日：2015-11-26
申请号：US14720105
申请日：2015-05-22
Applicant: Boston Scientific Scimed, Inc.
Inventor： Peter G. Edelman , Laura Elizabeth Christakis , Colby Harris , Paul E. Zarembo
CPC classification number: A61B17/00491 , A61B2017/003 , A61B2017/00495 , A61B2017/00522 , A61B2017/00867 , A61F2/2427 , A61F2/2433 , A61F2/2436 , A61F2/95 , A61F2/958 , A61F2/966 , A61F2220/0008 , A61F2220/005
Abstract: The present disclosure is directed to a delivery catheter with a mechanism of discharging an adhesive during and/or immediately prior to deployment of the medical device by the delivery catheter.
Abstract translation: 本公开涉及一种具有在输送导管期间和/或在其由医疗装置展开之前排出粘合剂的机构的输送导管。
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