公开(公告)号：US20070244131A1

公开(公告)日：2007-10-18

申请号：US11735751

申请日：2007-04-16

Applicant: Sungtaek Lim ,  Keith Harris ,  David Stefany ,  Charles Gardner ,  Bin Cao ,  Ray Boffey ,  Timothy Gillespy ,  Joacy Aguiar ,  Hazel Dyke ,  Elsa Dechaux

Inventor： Sungtaek Lim ,  Keith Harris ,  David Stefany ,  Charles Gardner ,  Bin Cao ,  Ray Boffey ,  Timothy Gillespy ,  Joacy Aguiar ,  Hazel Dyke ,  Elsa Dechaux

IPC: A61K31/506 ,  C07D239/47 ,  C07D239/48 ,  C07D239/52

CPC classification number: C07D239/42 ,  C07D239/47 ,  C07D239/48 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/10 ,  C07D403/12 ,  C07D405/04 ,  C07D405/10 ,  C07D405/12 ,  C07D405/14 ,  C07D409/04 ,  C07D409/12 ,  C07D413/04 ,  C07D413/10 ,  C07D413/12 ,  C07D413/14 ,  C07D417/04 ,  C07D417/14

Abstract: The present invention is directed to a compound of Formula (I) wherein Cy1, Cy2, L1, L2, and R1 are as defined herein, a pharmaceutical composition comprising a pharmaceutically effective amount of one or more compounds according to Formula (I) in admixture with a pharmaceutically acceptable carrier, and a method of treating a patient suffering from a PGD2-mediated disorder including, but not limited to, allergic disease (such as allergic rhinitis, allergic conjunctivitis, atopic dermatitis, bronchial asthma and food allergy), systemic mastocytosis, disorders accompanied by systemic mast cell activation, anaphylaxis shock, bronchoconstriction, bronchitis, urticaria, eczema, diseases accompanied by itch (such as atopic dermatitis and urticaria), diseases (such as cataract, retinal detachment, inflammation, infection and sleeping disorders) which is generated secondarily as a result of behavior accompanied by itch (such as scratching and beating), inflammation, chronic obstructive pulmonary diseases, ischemic reperfusion injury, cerebrovascular accident, chronic rheumatoid arthritis, pleurisy, ulcerative colitis and the like by administering to said patient a pharmaceutically effective amount of a compound according to Formula (I).

公开(公告)号：US20070053102A1

公开(公告)日：2007-03-08

申请号：US11218701

申请日：2005-09-02

Applicant: Bin Cao ,  Hung-Chin Guthrie ,  Wen-Chien Hsiao ,  Jyh-Shuey Lo

Inventor： Bin Cao ,  Hung-Chin Guthrie ,  Wen-Chien Hsiao ,  Jyh-Shuey Lo

IPC: G11B5/147

CPC classification number: G11B5/3116 ,  G11B5/3163

Abstract: A magnetic write head and method of manufacture thereof that has a first pole structure having a step notched first pole structure. The step notched structure includes a bottom notched portion that is wider than the second notched portion formed thereover. The upper, or narrower, notched portion has a width that is substantially equal to and self aligned with a second pole structure (P2) formed thereover. The invention may also include first and second wing portions formed in the first pole that are recessed from the ABS and that extend laterally from the first notched portions of the first pole. The formation of the winged portions is assisted by an ion mill resistant bump (alumina bump) formed thereover, which acts as a mask during the ion milling operations that are used to form the first and second notches.

Abstract translation: 一种磁写头及其制造方法，其具有第一极结构，具有阶切口第一极结构。 台阶缺口结构包括比形成在其上的第二切口部分更宽的底部切口部分。 上部或更窄的切口部分具有基本上等于并与其上形成的第二极结构（P 2）自对准的宽度。 本发明还可以包括形成在第一极中的从ABS凹入并从第一极的第一切口部横向延伸的第一和第二翼部。 翼形部分的形成由在其上形成的离子磨耐磨凸起（氧化铝凸块）辅助，其在用于形成第一和第二凹口的离子铣削操作期间用作掩模。

公开(公告)号：US5951163A

公开(公告)日：1999-09-14

申请号：US733113

申请日：1996-10-16

Applicant: Cheng-Kuei Jen ,  Ky Thanh Nguyen ,  Bin Cao ,  Hao Wang ,  Chee Ang Loong

Inventor： Cheng-Kuei Jen ,  Ky Thanh Nguyen ,  Bin Cao ,  Hao Wang ,  Chee Ang Loong

IPC: G01K11/24 ,  G01N29/07 ,  G01N29/22 ,  G01N29/24 ,  G01K11/22 ,  G01N29/18 ,  G01N29/20

CPC classification number: B29C45/78 ,  B22D17/32 ,  B22D2/006 ,  B29C45/76 ,  B29C47/92 ,  G01K11/24 ,  G01N29/07 ,  G01N29/228 ,  G01N29/2462 ,  B29C2945/7604 ,  B29C2945/7605 ,  B29C2945/76083 ,  B29C2945/76103 ,  B29C2945/76287 ,  B29C2945/76301 ,  B29C2945/76381 ,  B29C2945/76474 ,  B29C2947/92085 ,  B29C2947/92171 ,  B29C2947/922 ,  B29C2947/92209 ,  B29C2947/92285 ,  B29C45/1642 ,  B29C45/1704 ,  B29C47/0016 ,  B29C47/004 ,  G01N2291/011 ,  G01N2291/015 ,  G01N2291/0252 ,  G01N2291/02836 ,  G01N2291/02854 ,  G01N2291/02881 ,  G01N2291/0422

Abstract: Ultrasonic sensors and associated methods for on-line monitoring of material properties for die casting, molding and extrusion processes at elevated temperatures are disclosed. The sensors include the use of ultrasonic waveguides embedded in the processing machines and piezoelectric ultrasonic transducers. The sensors are operated in the reflection geometry in which one side access of the processing machines is required. The monitoring parameters are the flow front, gap development and temperature of the materials being processed and filled in the cavities of the die in casting processes and the mold in injection molding, and the temperature and viscosity of the molten polymers in the polymer extrusion machines. Piezoelectric ultrasonic transducers made of high Curie temperature materials, fabricated by sol-gel techniques and directly deposited on top of the ultrasonic waveguides or the external walls of the shot sleeve of the die caster, die of the die caster, mold of the injection molding machine or barrel of the extruder are also used.

Abstract translation: 公开了超声波传感器和用于在高温下压铸，模塑和挤出工艺的材料性质的在线监测的相关方法。 这些传感器包括使用嵌入在处理机器中的超声波波导和压电超声换能器。 传感器以需要加工机器一侧接近的反射几何形式工作。 监测参数是在铸造过程中模具的空腔中的流动前沿，间隙开发和被处理和填充的材料的温度以及注模中的模具以及聚合物挤出机中熔融聚合物的温度和粘度。 由高居里温度材料制成的压电超声换能器，通过溶胶 - 凝胶技术制造，直接沉积在模具脚轮的超声波波导管或喷射套筒的外壁上，模具脚轮的模具，注塑机的模具 或桶的挤出机也被使用。

公开(公告)号：US09545184B2

公开(公告)日：2017-01-17

申请号：US13812244

申请日：2011-08-24

Applicant: Huasong Zhou ,  Li Jiang ,  Jianmin Chen ,  Bin Cao

Inventor： Huasong Zhou ,  Li Jiang ,  Jianmin Chen ,  Bin Cao

IPC: A47L15/42 ,  B05B1/18 ,  B05B7/04 ,  B05B7/08

CPC classification number: A47L15/4278 ,  B05B1/18 ,  B05B7/0425 ,  B05B7/0846

Abstract: A rich air sprayer of sanitary ware has a base, the base is disposed with at least two waterways; each waterway includes an inlet hole, a mutation cavity connected to the inlet hole and an air inlet hole connected to the mutation cavity, the flow area of the inlet hole is smaller than that of the mutation cavity, negative pressure is generated inside the mutation cavity when the water flows from the inlet hole into the mutation cavity, the negative pressure makes the mutation cavity suck air from the outside of the sprayer through the air inlet hole, the air and the water are mixed to form bubbles; the outlets of the mutation cavities intersect or the tangents of the outlets of the mutation cavities intersect, making the water flowing out of the outlets of the mutation cavities collide to enhance the granular sensation.

Abstract translation: 卫生洁具的富气喷雾器有底座，底座至少配有两条水路; 每个水道包括入口孔，连接到入口孔的突变腔和连接到突变腔的空气入口孔，入口孔的流动面积小于突变腔的流动面积，在突变腔内产生负压 当水从入口孔流入突变腔时，负压使得突变腔从喷雾器的外部通过进气孔吸入空气，空气和水混合形成气泡; 突变腔的出口相交或突变腔的出口的切线相交，使得从突变腔的出口流出的水碰撞以增强颗粒感。

公开(公告)号：US20150099005A1

公开(公告)日：2015-04-09

申请号：US14510442

申请日：2014-10-09

Applicant: Gang Cheng ,  Qiong Tang ,  Bin Cao

Inventor： Gang Cheng ,  Qiong Tang ,  Bin Cao

IPC: A61K47/48 ,  A61K31/7088 ,  A61K31/4745

CPC classification number: A61K47/59 ,  A61K31/4745 ,  A61K31/713 ,  A61K45/06 ,  A61K47/645 ,  A61K2300/00

Abstract: A high drug loading system is described comprising of at least one anticancer drug; at least one peptide; and at least one nucleic acid.

Abstract translation: 描述了包含至少一种抗癌药物的高药物装载系统; 至少一种肽; 和至少一种核酸。

公开(公告)号：US20130119286A1

公开(公告)日：2013-05-16

申请号：US13811017

申请日：2011-08-16

Applicant: Huasong Zhou ,  Libin Shen ,  Jianmin Chen ,  Bin Cao

Inventor： Huasong Zhou ,  Libin Shen ,  Jianmin Chen ,  Bin Cao

IPC: F16K31/44

CPC classification number: F16K31/44 ,  B05B1/1636 ,  B05B1/18 ,  Y10T137/87877

Abstract: A touch switch outlet mechanism has a fixation unit and a switch unit. The fixation unit includes an inlet waterway connected to the water source, a water diversion cavity connected to the inlet waterway, N number of water diversion holes connected to the water diversion cavity and several outlet functions with same number as the water diversion holes and one to one corresponding to the water diversion holes, N is equal to or more than 2; The switch unit includes N−1 number of sealing balls and N touch buttons, the N touch buttons are separately disposed with a touch end inside the water diversion cavity and a controlled end controlled by the user, the touch ends of the N touch buttons corresponding to N water diversion holes and sliding connected to the fixation unit, the N−1 sealing balls can close N−1 of the N water diversion holes.

Abstract translation: 触摸开关插座机构具有固定单元和开关单元。 固定单元包括连接到水源的入口水道，连接到入口水道的分水腔，连接到引水腔的N个分水孔和与导水孔相同数量的多个出水口功能，一个至 一个对应于导水孔，N等于或大于2; 开关单元包括N-1个密封球和N个触摸按钮，N个触摸按钮分别设置在引水腔内部的触摸端和由用户控制的受控端，N个触摸按钮的触摸端对应 到N个分水孔并滑动连接到固定单元，N-1个密封球可以关闭N个分水孔的N-1个。

公开(公告)号：US08170074B2

公开(公告)日：2012-05-01

申请号：US13082690

申请日：2011-04-08

Applicant: Bin Cao ,  Douglas James Beckett ,  Tom Luk ,  Rong Chen

Inventor： Bin Cao ,  Douglas James Beckett ,  Tom Luk ,  Rong Chen

IPC: H01S3/00 ,  H01S3/13 ,  H01S3/091

CPC classification number: H01S5/0683 ,  H01S5/06804

Abstract: A method of estimating an injection power of seed light injected into an injection-seeded transmitter. A back face monitoring (BFM) response of the injection-seeded transmitter is determined, and data representative of the BFM response stored in a memory. During run-time, a controller of the injection-seeded transmitter, detects a temperature of the injection-seeded transmitter and an instantaneous BFM current. BFM response data is obtained from the memory based on the detected temperature, and the seed light injection power estimated based on the obtained data and the detected instantaneous BFM current.

Abstract translation: 一种估计注入种子发射机的种子光的注入功率的方法。 确定注入种子发送器的背面监视（BFM）响应，并将表示BFM响应的数据存储在存储器中。 在运行期间，注入种子发射器的控制器检测注射种子发射器的温度和瞬时BFM电流。 基于检测到的温度从存储器获得BFM响应数据，并且基于获得的数据估计的种子光注入功率和检测到的瞬时BFM电流。

公开(公告)号：US07940822B1

公开(公告)日：2011-05-10

申请号：US12620745

申请日：2009-11-18

Applicant: Bin Cao ,  Douglas James Beckett ,  Tom Luk ,  Rong Chen

Inventor： Bin Cao ,  Douglas James Beckett ,  Tom Luk ,  Rong Chen

IPC: H01S3/13 ,  H01S3/00

CPC classification number: H01S5/0683 ,  H01S5/06804

Abstract: A method of estimating an injection power of seed light injected into an injection-seeded transmitter. A back face monitoring (BFM) response of the injection-seeded transmitter is determined, and data representative of the BFM response stored in a memory. During run-time, a controller of the injection-seeded transmitter, detects a temperature of the injection-seeded transmitter and an instantaneous BFM current. BFM response data is obtained from the memory based on the detected temperature, and the seed light injection power estimated based on the obtained data and the detected instantaneous BFM current.

Abstract translation: 一种估计注入种子发射机的种子光的注入功率的方法。 确定注入种子发送器的背面监视（BFM）响应，并将表示BFM响应的数据存储在存储器中。 在运行期间，注入种子发射机的控制器检测注入种子发射机的温度和瞬时BFM电流。 基于检测到的温度从存储器获得BFM响应数据，并且基于获得的数据估计的种子光注入功率和检测到的瞬时BFM电流。

公开(公告)号：US20100046949A1

公开(公告)日：2010-02-25

申请号：US12194912

申请日：2008-08-20

Applicant: John Bainbridge ,  Tom Luk ,  Bin Cao

Inventor： John Bainbridge ,  Tom Luk ,  Bin Cao

IPC: H04J14/02

CPC classification number: H04J14/0221 ,  H04B10/506 ,  H04J14/0226 ,  H04J14/0227

Abstract: Described is a method for controlling the wavelength of a laser in a wavelength division multiplexed (WDM) system. The method includes generating broadband light having a dithered optical power and a wavelength spectrum that includes a plurality of WDM wavelengths. The broadband light is spectrally filtered to generate a spectrally-sliced optical signal having a wavelength spectrum that includes one of the WDM wavelengths. The spectrally-sliced optical signal is injected into a laser and a dithered optical power of the laser is determined. A parameter of the laser is controlled in response to the determination of the dithered optical power to thereby align a wavelength of the laser to the wavelength spectrum of the spectrally-sliced optical signal.

Abstract translation: 描述了一种用于控制波分复用（WDM）系统中的激光波长的方法。 该方法包括产生具有抖动光功率的宽带光和包括多个WDM波长的波长光谱。 对宽带光进行频谱滤波以产生具有包括WDM波长之一的波长谱的光谱切片光信号。 将光谱切片的光信号注入到激光器中，确定激光的抖动光焦度。 响应于抖动光焦度的确定来控制激光器的参数，从而将激光器的波长与光谱切片的光信号的波长光谱对准。

公开(公告)号：US10058620B2

公开(公告)日：2018-08-28

申请号：US14621904

申请日：2015-02-13

Applicant: Gang Cheng ,  Qiong Tang ,  Bin Cao

Inventor： Gang Cheng ,  Qiong Tang ,  Bin Cao

IPC: A61K47/48 ,  A61K48/00 ,  C12N15/87 ,  A61K47/61 ,  A61K47/64

CPC classification number: A61K47/645 ,  A61K47/61 ,  C12N15/87 ,  C12N2810/40

Abstract: One or more embodiments of the present invention provide a novel composition for gene delivery are directed to a group of polysaccharide polymers, having one or more nucleic acid delivery side chains comprising cationic peptides. In some embodiments, these cationic peptides condense and physically bond to one or more nucleic acids to form a polysaccharide-nucleic acid complex that permits delivery to and transfection of the nucleic acid(s) into cells. In some embodiments, the polysaccharide polymers of the present invention may also have one or more zwitterionic side chains and/or reactive side chains.