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26 条记录 (耗时 0.032 秒)

    Method, System, and Computer Program Product For Tracking of Blood Glucose Variability in Diabetes
    12.
    发明申请
    Method, System, and Computer Program Product For Tracking of Blood Glucose Variability in Diabetes 有权
    方法，系统和计算机程序产品用于跟踪糖尿病血糖变异性

    公开(公告)号：US20110264378A1

    公开(公告)日：2011-10-27

    申请号：US13131467

    申请日：2009-11-24

    申请人： Marc D. Breton ,  Boris P. Kovatchev

    发明人： Marc D. Breton ,  Boris P. Kovatchev

    IPC分类号： G06F19/00 ,  G01N33/48

    CPC分类号： G16H40/63 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/7275 ,  G06F19/00 ,  G16H10/20 ,  G16H50/20

    摘要： An embodiment may be in the field of glycemic analysis and control. More specifically, an embodiment or approach may provide a novel method, system, and computer program for the visual and quantitative tracking of blood glucose variability in diabetes from self-monitoring blood glucose (SMBG) data and/or continuous glucose monitoring (CGM) data. More particularly, an embodiment or aspects thereof may use glucose measurements obtained from self-monitoring data and/or CGM data of an individual or a group of individuals to track and analyze blood glucose variability.

    摘要翻译： 一个实施方案可能在血糖分析和控制领域。 更具体地，实施例或方法可以提供用于从自我监测血糖（SMBG）数据和/或连续葡萄糖监测（CGM）数据来视觉和定量跟踪糖尿病血糖变异性的新方法，系统和计算机程序 。 更具体地，其实施方案或其方面可以使用从个体或一组个体的自我监测数据和/或CGM数据获得的葡萄糖测量值来跟踪和分析血糖变异性。

    Method, Computer Program Product and System for Individual Assessment of Alcohol Sensitivity
    14.
    发明申请
    Method, Computer Program Product and System for Individual Assessment of Alcohol Sensitivity 审中-公开
    方法，计算机程序产品和酒精敏感性个体评估系统

    公开(公告)号：US20110264374A1

    公开(公告)日：2011-10-27

    申请号：US12674348

    申请日：2008-08-20

    申请人： Bankole A. Johnson ,  Nassima Ait-Daoud Tiouririne ,  Marc D. Breton ,  Boris P. Kovatchev

    发明人： Bankole A. Johnson ,  Nassima Ait-Daoud Tiouririne ,  Marc D. Breton ,  Boris P. Kovatchev

    IPC分类号： G06F19/00

    CPC分类号： G16B5/00

    摘要： Methods/computer methods and systems/computer systems for the evaluation of two idiosyncratic indices of alcohol intoxication: the Alcohol Sensitivity Index (ASI), and the brain-specific Cognitive Alcohol Sensitivity Index (CASI). The two indices are based on the new Metabolic and Cognitive Minimal Models of Alcohol Dynamics, and are derived from specific clinical protocols, accompanied by specific data analysis procedures. The two indices may be derived from specific clinical and cognitive assessment protocols, accompanied by specific data analysis procedures based on the new metabolic and cognitive minimal models of alcohol dynamics.

    摘要翻译： 方法/计算机方法和系统/计算机系统，用于评估酒精中毒的两种特异性指标：酒精敏感指数（ASI）和脑特异性认知酒精敏感性指数（CASI）。 这两个指标基于酒精动力学的新型代谢和认知最小模型，并且来自具体的临床方案，并伴有特定的数据分析程序。 这两个指标可能来自特定的临床和认知评估方案，并伴随着基于酒精动力学的新代谢和认知最小模型的特定数据分析程序。

    Method, System and Computer Simulation Environment for Testing of Monitoring and Control Strategies in Diabetes
    15.
    发明申请
    Method, System and Computer Simulation Environment for Testing of Monitoring and Control Strategies in Diabetes 审中-公开
    糖尿病监测与控制策略检测方法，系统与计算机仿真环境

    公开(公告)号：US20100179768A1

    公开(公告)日：2010-07-15

    申请号：US12664444

    申请日：2008-06-20

    申请人： Boris P. Kovatchev ,  Marc D. Breton ,  Claudio Cobelli ,  Chiara Dalla Man

    发明人： Boris P. Kovatchev ,  Marc D. Breton ,  Claudio Cobelli ,  Chiara Dalla Man

    IPC分类号： G06F19/00 ,  G01N33/48

    摘要： A simulation environment for in silico testing of monitoring methods, open-loop and closed-loop treatment strategies in type 1 diabetes. Some exemplary principal components of the simulation environment comprise, but not limited thereto, the following: 1) a “population” of in silico “subjects” with type 1 diabetes in three age groups; 2) a simulator of CGM sensor errors; 3) a simulator of insulin pumps and discrete insulin delivery; 4) an interface allowing the input of user-specified treatment scenarios; and 5) a set of standardized outcome measures and graphs evaluating the quality of the tested treatment strategies. These components can be used separately or in combination for the preclinical evaluation of open-loop or closed-loop control treatments of diabetes.

    摘要翻译： 1型糖尿病监测方法，开环和闭环治疗策略的电脑测试模拟环境。 模拟环境的一些示例性主要组成部分包括但不限于以下内容：1）在三个年龄组中具有1型糖尿病的计算机“受试者”的“群体” 2）CGM传感器误差的模拟器; 3）胰岛素泵和离散胰岛素输送的模拟器; 4）允许输入用户指定的治疗方案的界面; 和5）一套评估测试治疗策略质量的标准化结果测量和图表。 这些组分可以单独使用或组合使用，用于糖尿病的开环或闭环控制治疗的临床前评估。

    Method, system, and computer program product for tracking of blood glucose variability in diabetes
    16.
    发明授权
    Method, system, and computer program product for tracking of blood glucose variability in diabetes 有权
    用于跟踪糖尿病血糖变异性的方法，系统和计算机程序产品

    公开(公告)号：US09317657B2

    公开(公告)日：2016-04-19

    申请号：US13131467

    申请日：2009-11-24

    申请人： Marc D. Breton ,  Boris P. Kovatchev

    发明人： Marc D. Breton ,  Boris P. Kovatchev

    IPC分类号： G06F19/00 ,  G01N33/48 ,  A61B5/00 ,  A61B5/145

    CPC分类号： G16H40/63 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/7275 ,  G06F19/00 ,  G16H10/20 ,  G16H50/20

    摘要： An embodiment may be in the field of glycemic analysis and control. More specifically, an embodiment or approach may provide a novel method, system, and computer program for the visual and quantitative tracking of blood glucose variability in diabetes from self-monitoring blood glucose (SMBG) data and/or continuous glucose monitoring (CGM) data. More particularly, an embodiment or aspects thereof may use glucose measurements obtained from self-monitoring data and/or CGM data of an individual or a group of individuals to track and analyze blood glucose variability.

    摘要翻译： 一个实施方案可能在血糖分析和控制领域。 更具体地，实施例或方法可以提供用于从自我监测血糖（SMBG）数据和/或连续葡萄糖监测（CGM）数据来视觉和定量跟踪糖尿病血糖变异性的新方法，系统和计算机程序 。 更具体地，其实施方案或其方面可以使用从个体或一组个体的自我监测数据和/或CGM数据获得的葡萄糖测量值来跟踪和分析血糖变异性。

    Tracking the probability for imminent hypoglycemia in diabetes from self-monitoring blood glucose (SMBG) data
    19.
    发明授权
    Tracking the probability for imminent hypoglycemia in diabetes from self-monitoring blood glucose (SMBG) data 有权

    公开(公告)号：US10431342B2

    公开(公告)日：2019-10-01

    申请号：US13394091

    申请日：2010-09-02

    申请人： Boris P. Kovatchev ,  Marc D. Breton

    发明人： Boris P. Kovatchev ,  Marc D. Breton

    IPC分类号： G01N33/48 ,  G16H50/50 ,  G06F19/00 ,  A61B5/00

    摘要： A method, system and related computer program product for tracking the probability of hypoglycemia from routine self-monitoring of blood glucose (SMBG) data in patients with diabetes. A specific bivariate probability distribution of low BG events based jointly on the Low BG Index (LBGI) and the Average Daily Risk Range (ADRR) is used to predict hypoglycemia probability of occurrence from inputted SMBG data. The SMBG data is retrieved from a series of SMBG data of a patient available from the patient's glucose meter and allows tracking of the probability for future hypoglycemia over a predetermined duration, e.g., a 24 or 48 hour period. The tracking includes presentation of visual and/or numerical output, as we construction of hypoglycemia risk trajectories that would enable warning messages for crossing of predefined thresholds, such as 50% likelihood for upcoming hypoglycemia below 50 mg/dl.

    Method, system, and computer program product for the detection of physical activity by changes in heart rate, assessment of fast changing metabolic states, and applications of closed and open control loop in diabetes
    20.
    发明授权
    Method, system, and computer program product for the detection of physical activity by changes in heart rate, assessment of fast changing metabolic states, and applications of closed and open control loop in diabetes 有权
    用于通过心率变化检测身体活动的方法，系统和计算机程序产品，快速变化的代谢状态的评估以及闭合和开放的控制回路在糖尿病中的应用

    公开(公告)号：US08585593B2

    公开(公告)日：2013-11-19

    申请号：US12516044

    申请日：2007-11-27

    申请人： Boris P. Kovatchev ,  Marc D. Breton

    发明人： Boris P. Kovatchev ,  Marc D. Breton

    IPC分类号： A61B5/05

    CPC分类号： A61B5/4839 ,  A61B5/024 ,  A61B5/14532 ,  A61B5/222 ,  A61B5/4866 ,  G06F19/00 ,  G06F19/3456 ,  G16H50/50

    摘要： A method, system, and computer program product related to the detection of physical activity using changes in heart rate. The method, system, and computer program product evaluates short term glucose demand and long term insulin action due to physical activity. The method, system, and computer program product is further related to the improvement of open and closed loop control of diabetes by accounting for the metabolic changes due to physical activity. The method, system, and computer program product is directed to detecting in real time the short and long term effects of physical activity on insulin action via heart rate analysis, and recommending changes in insulin dosing to compensate for the effects of physical activity. With these recommendations, the open and closed loop control of diabetes can be improved and steps can be taken to prevent hypoglycemia that may result from increased insulin sensitivity due to physical activity.

    摘要翻译： 与使用心率变化的身体活动检测相关的方法，系统和计算机程序产品。 方法，系统和计算机程序产品评估短期葡萄糖需求和由于身体活动导致的长期胰岛素作用。 方法，系统和计算机程序产品进一步涉及由于身体活动导致的代谢变化，改善糖尿病的开放和闭环控制。 方法，系统和计算机程序产品旨在通过心率分析实时检测身体活动对胰岛素作用的短期和长期影响，并建议胰岛素给药的变化以补偿身体活动的影响。 通过这些建议，可以改善糖尿病的开放和闭环控制，并且可以采取措施来预防由于身体活动而增加的胰岛素敏感性可能导致的低血糖。