公开(公告)号：US5662690A

公开(公告)日：1997-09-02

申请号：US672739

申请日：1996-06-28

申请人： Clinton Cole ,  Carlton B. Morgan ,  Judi Cyrus ,  Daniel Powers

发明人： Clinton Cole ,  Carlton B. Morgan ,  Judi Cyrus ,  Daniel Powers

IPC分类号： A61N1/39

CPC分类号： A61N1/39

摘要： A defibrillator featuring a treatment mode and a training mode comprises an energy source, an electrode connector, a controller, and training mode circuitry. The controller comprises a feature for connecting the energy source to the electrode connector and a pause actuator for permitting a user to inhibit electrical stimulation when no longer required. The training mode circuitry simulates the operation of the defibrillator in treatment mode. The defibrillator also includes a method of operating comprising the steps of: 1) providing a defibrillator having an energy source, a controller, and electrode connectors, wherein the controller further comprises circuits for actuating the defibrillator to deliver a defibrillation shock from the defibrillation energy source to the electrode connectors and 2) operating the defibrillator in a training mode to simulate delivery of a defibrillation shock from the energy source to the electrode connectors without delivering a defibrillation shock from the energy source to the electrode connectors.

摘要翻译： 具有治疗模式和训练模式的除颤器包括能量源，电极连接器，控制器和训练模式电路。 该控制器包括用于将能量源连接到电极连接器的特征和用于允许用户在不再需要时抑制电刺激的暂停致动器。 训练模式电路模拟除颤器在治疗模式下的运行。 除颤器还包括一种操作方法，包括以下步骤：1）提供具有能量源，控制器和电极连接器的除颤器，其中所述控制器还包括用于致动所述去纤维性颤动器以从除颤能量源传递除颤电击的电路 到电极连接器，以及2）以训练模式操作除颤器，以模拟从能量源到电极连接器的除颤冲击的传送，而不会将电能从源电极传递到电极连接器。

公开(公告)号：US5549115A

公开(公告)日：1996-08-27

申请号：US314395

申请日：1994-09-28

申请人： Carlton B. Morgan ,  Clinton Cole ,  Daniel J. Powers

发明人： Carlton B. Morgan ,  Clinton Cole ,  Daniel J. Powers

IPC分类号： A61B5/0432 ,  A61N5/04 ,  G01D3/02 ,  G01D9/00 ,  G06F17/40 ,  G06F19/00

CPC分类号： G06F19/3406 ,  G01D3/02 ,  G01D9/005 ,  G06F19/3487 ,  A61B5/0432 ,  A61N1/39

摘要： A method for gathering event data using a data gathering instrument having an instrument clock and an instrument data storage medium, the method comprising the steps of: gathering event data using the data gathering instrument; storing the event data in an instrument data storage medium; using an instrument clock to associate time information with the event data; storing the associated time information in the instrument data storage medium; separating the instrument data storage medium from the data gathering instrument; separating the instrument clock from the data gathering instrument; and storing in a main data storage medium the event data and the time information stored in the instrument data storage medium. The invention also includes a data gathering system practicing this method, the data gathering instrument itself, and removable instrument clock and memory modules, preferably disposed together in a housing such as a PCMCIA format card.

摘要翻译： 一种使用具有仪器时钟和仪器数据存储介质的数据采集仪器收集事件数据的方法，所述方法包括以下步骤：使用所述数据采集仪器收集事件数据; 将事件数据存储在仪器数据存储介质中; 使用仪器时钟将时间信息与事件数据相关联; 将所述相关时间信息存储在所述仪器数据存储介质中; 将仪器数据存储介质与数据采集仪器分离; 将仪器时钟与数据采集仪器分离; 并在主数据存储介质中存储存储在仪器数据存储介质中的事件数据和时间信息。 本发明还包括实施该方法的数据收集系统，数据收集工具本身和可移除的仪器时钟和存储器模块，优选地一起设置在诸如PCMCIA格式卡的壳体中。

公开(公告)号：US5237989A

公开(公告)日：1993-08-24

申请号：US681347

申请日：1991-04-04

申请人： Carlton B. Morgan ,  Joseph E. Szyperski

发明人： Carlton B. Morgan ,  Joseph E. Szyperski

IPC分类号： A61N1/39

CPC分类号： A61N1/39 ,  A61N1/3912

摘要： Disclosed is a cardiac defibrillator for providing a cardiac defibrillation pulse to a patient. The defibrillator comprises a switch contact (14) mounted on a movable switch (10) that moves between a charge position and a discharge position. In the charge position, the switch contact is coupled to a high-voltage battery (22) in order to provide a charge to an energy storage capacitor (30). When the movable switch is released from the charge position, the switch contact engages an electrode contact (32) and a defibrillation pulse flows into a patient (40). The duration of the cardiac defibrillation pulse can be varied by changing the length of time that the switch contact remains engaged with electrode contact. Also disposed within the switch contact path is a discharge contact (42), which is connected to a discharge resistor (48). When the movable switch is in a discharge position, the switch contact is engaged with the discharge contact thereby allowing the discharge resistor to dissipate charge from the energy storage capacitor. A spring (16) is connected to the movable switch in order to rotate it between the charge and discharge positions.

公开(公告)号：US20120316630A1

公开(公告)日：2012-12-13

申请号：US13587607

申请日：2012-08-16

申请人： Andrew D. Firlik ,  Jeffrey Balzer ,  Bradford Evan Gliner ,  Alan J. Levy ,  Carlton B. Morgan ,  Katrina S. Firlik

发明人： Andrew D. Firlik ,  Jeffrey Balzer ,  Bradford Evan Gliner ,  Alan J. Levy ,  Carlton B. Morgan ,  Katrina S. Firlik

IPC分类号： A61N1/05

CPC分类号： A61N1/375 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/0539 ,  A61N1/36017 ,  A61N1/36025 ,  A61N1/36082 ,  A61N1/36103 ,  A61N1/3756

摘要： The following disclosure describes several methods and apparatus for intracranial electrical stimulation to treat or otherwise effectuate a change in neural-functions of a patient. The methods in accordance with the invention can be used to treat brain damage (e.g., stroke, trauma, etc.), brain disease (e.g., Alzheimer's, Pick's, Parkinson's, etc.), and/or brain disorders (e.g., epilepsy, depression, etc.). The methods in accordance with the invention can also be used to enhance neural-function of normal, healthy brains (e.g., learning, memory, etc.), or to control sensory functions (e.g., pain).

公开(公告)号：US07577481B2

公开(公告)日：2009-08-18

申请号：US11355038

申请日：2006-02-15

申请人： Andrew D. Firlik ,  Jeffrey Balzer ,  Bradford Evan Gliner ,  Alan J. Levy ,  Carlton B. Morgan ,  Katrina S. Firlik

发明人： Andrew D. Firlik ,  Jeffrey Balzer ,  Bradford Evan Gliner ,  Alan J. Levy ,  Carlton B. Morgan ,  Katrina S. Firlik

IPC分类号： A61N1/18

CPC分类号： A61N1/375 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/0539 ,  A61N1/36017 ,  A61N1/36025 ,  A61N1/36082 ,  A61N1/36103 ,  A61N1/3756

摘要： The following disclosure describes a method for intracranial electrical stimulation to treat or otherwise effectuate a change in neural-functions of a patient. Several embodiments are directed toward enhancing or otherwise inducing a lasting change in neural activity to effectuate a particular neural-function. Such lasting change in neural activity is defined as “neuroplasticity.” The methods can be used to treat brain damage (e.g., stroke, trauma, etc.), brain disease (e.g., Alzheimer's, Pick's, Parkinson's, etc.), and/or brain disorders (e.g., epilepsy, depression, etc.). The methods can also be used to enhance neural-function of normal, healthy brains (e.g., learning, memory, etc.), or to control sensory functions (e.g., pain).

摘要翻译： 以下公开描述了一种用于颅内电刺激治疗或以其他方式实现患者神经功能变化的方法。 几个实施例旨在增强或以其他方式诱导神经活动的持续变化以实现特定的神经功能。 这种神经活动的持续变化被定义为“神经可塑性”。 这些方法可用于治疗脑损伤（例如卒中，创伤等），脑部疾病（如阿尔茨海默病，皮克病，帕金森病等）和/或脑部疾病（例如癫痫，抑郁症等） 。 该方法还可以用于增强正常，健康的大脑（例如学习，记忆等）的神经功能，或控制感觉功能（例如疼痛）。

公开(公告)号：US20080161881A1

公开(公告)日：2008-07-03

申请号：US11834650

申请日：2007-08-06

申请人： Andrew W. Firlik ,  Jeffrey Balzer ,  Bradford Evan Gliner ,  Alan J. Levy ,  Carlton B. Morgan ,  Katrina S. Firlik

发明人： Andrew W. Firlik ,  Jeffrey Balzer ,  Bradford Evan Gliner ,  Alan J. Levy ,  Carlton B. Morgan ,  Katrina S. Firlik

IPC分类号： A61N1/05

CPC分类号： A61N1/375 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/0539 ,  A61N1/36017 ,  A61N1/36025 ,  A61N1/36082 ,  A61N1/36103 ,  A61N1/3756

摘要： The following disclosure describes several methods and apparatus for intracranial electrical stimulation to treat or otherwise effectuate a change in neural-functions of a patient. Several embodiments of methods in accordance with the invention are directed toward enhancing or otherwise inducing a lasting change in neural activity to effectuate a particular neural-function. Such lasting change in neural activity is defined as “neuroplasticity.” The methods in accordance with the invention can be used to treat brain damage (e.g., stroke, trauma, etc.), brain disease (e.g., Alzheimer's, Pick's, Parkinson's, etc.), and/or brain disorders (e.g., epilepsy, depression, etc.). The methods in accordance with the invention can also be used to enhance neural-function of normal, healthy brains (e.g., learning, memory, etc.), or to control sensory functions (e.g., pain). Certain embodiments of methods in accordance with the invention electrically stimulate the brain at a stimulation site where neuroplasticity is occurring. The stimulation site may be different than the region in the brain where neural activity is typically present to perform the particular neural function according to the functional organization of the brain. In one embodiment in which neuroplasticity related to the neural-function occurs in the brain, the method can include identifying the location where such neuroplasticity is present. In an alternative embodiment in which neuroplasticity is not occurring in the brain, an alternative aspect is to induce neuroplasticity at a stimulation site where it is expected to occur. Several embodiments of these methods that are expected to produce a lasting effect on the intended neural activity at the stimulation site use electrical pulses that increase the resting membrane potential of neurons at the stimulation site to a subthreshold level.

公开(公告)号：US06374137B1

公开(公告)日：2002-04-16

申请号：US09417269

申请日：1999-10-13

申请人： Carlton B. Morgan ,  Bradford E. Gliner ,  Dawn Jorgenson ,  Kent W. Leyde

发明人： Carlton B. Morgan ,  Bradford E. Gliner ,  Dawn Jorgenson ,  Kent W. Leyde

IPC分类号： A61N139

CPC分类号： A61N1/3937 ,  A61N1/3931

摘要： An energy reduction unit is removably connectable to an external defibrillator to reduce the defibrillation energy delivered by the defibrillator to a patient. Use of the energy reduction unit is particularly suited to defibrillating pediatric patients (infants and children under 8) with an automatic or semi-automatic external defibrillator (AED). In one embodiment, the energy reduction unit includes an attenuator which partially dissipates energy produced by the AED. The attenuator is advantageously designed to present an impedance to the AED which, when connected to the patient, is approximately equal to the patient's impedance. The energy reduction unit may include a presence-detect function which enables the defibrillator to modify analysis of ECG signals to account for differences heart rhythms of pediatric and adult patients. In a second embodiment, the energy reduction unit includes an energy control modifier circuit which affects the charging operations performed internal to the AED. Other than being attached to the defibrillation equipment, the energy reduction unit does not otherwise change how an operator uses the equipment.

摘要翻译： 能量减少单元可拆卸地连接到外部除颤器，以减少除颤器向患者传递的除颤能量。 能量减少装置的使用特别适用于使用自动或半自动外部除颤器（AED）除纤维化的儿科患者（8岁以下的婴儿和8岁以下的儿童）。 在一个实施例中，能量减少单元包括部分耗散由AED产生的能量的衰减器。 衰减器有利地被设计成向AED呈现阻抗，其在连接到患者时大致等于患者的阻抗。 能量减少单元可以包括存在检测功能，其使除颤器能够修改ECG信号的分析，以解决儿科和成人患者的心律的差异。 在第二实施例中，能量减少单元包括影响在AED内部执行的充电操作的能量控制修正器电路。 除了附着到除颤设备之外，能量减少单元不会改变操作者如何使用设备。

公开(公告)号：US6016059A

公开(公告)日：2000-01-18

申请号：US467062

申请日：1995-06-06

申请人： Carlton B. Morgan

发明人： Carlton B. Morgan

IPC分类号： A61N1/39 ,  G01R27/26

CPC分类号： A61N1/3931

摘要： A defibrillator and electrode system that gives the user a visible and/or audible indication of the condition of the electrodes and other parts of the defibrillator system prior to deployment of the electrodes and use of the defibrillator. In a preferred embodiment of the method of this invention, a patient simulation and analyze circuit within the defibrillator periodically tests the condition of the system and provides the user with a visual indication of the system's condition.

摘要翻译： 除颤器和电极系统，其在部署电极和使用除颤器之前向用户提供电极和除颤器系统的其他部分的状况的可见和/或可听见的指示。 在本发明方法的优选实施例中，除颤器内的患者模拟和分析电路周期性地测试系统的状况并向用户提供系统状况的视觉指示。

公开(公告)号：US5593427A

公开(公告)日：1997-01-14

申请号：US601617

申请日：1996-02-14

申请人： Bradford E. Gliner ,  Thomas D. Lyster ,  Clinton S. Cole ,  Daniel J. Powers ,  Carlton B. Morgan

发明人： Bradford E. Gliner ,  Thomas D. Lyster ,  Clinton S. Cole ,  Daniel J. Powers ,  Carlton B. Morgan

IPC分类号： A61N1/39

CPC分类号： A61N1/3937 ,  A61N1/3906 ,  A61N1/3912

摘要： This invention provides an external defibrillator and defibrillation method that automatically compensates for patient-to-patient impedance differences in the delivery of electrotherapeutic pulses for defibrillation and cardioversion. In a preferred embodiment, the defibrillator has an energy source that may be discharged through electrodes on the patient to provide a biphasic voltage or current pulse. In one aspect of the invention, the first and second phase duration and initial first phase amplitude are predetermined values. In a second aspect of the invention, the duration of the first phase of the pulse may be extended if the amplitude of the first phase of the pulse fails to fall to a threshold value by the end of the predetermined first phase duration, as might occur with a high impedance patient. In a third aspect of the invention, the first phase ends when the first phase amplitude drops below a threshold value or when the first phase duration reaches a threshold time value, whichever comes first, as might occur with a low to average impedance patient. This method and apparatus of altering the delivered biphasic pulse thereby compensates for patient impedance differences by changing the nature of the delivered electrotherapeutic pulse, resulting in a smaller, more efficient and less expensive defibrillator.

摘要翻译： 本发明提供一种外部除颤器和除颤方法，其自动补偿用于除颤和心脏复律的电疗脉冲递送中的患者对患者的阻抗差异。 在优选实施例中，除颤器具有能够通过患者身上的电极排出的能量源，以提供双相电压或电流脉冲。 在本发明的一个方面，第一和第二相位持续时间和初始第一相位振幅是预定值。 在本发明的第二方面中，如果在预定的第一相位持续时间结束时脉冲的第一相位的幅度不能下降到阈值，则脉冲的第一相位的持续时间可能会延长 与高阻抗患者。 在本发明的第三方面中，当第一相位幅度下降到低于阈值时或当第一相位持续时间达到阈值时间值（以先到者为准）时，第一相位结束，如同低平均阻抗患者可能发生的那样。 改变输送的双相脉冲的这种方法和装置由此通过改变递送的电疗脉冲的性质来补偿患者的阻抗差异，导致更小，更有效和更便宜的除颤器。

公开(公告)号：US5591213A

公开(公告)日：1997-01-07

申请号：US532863

申请日：1995-09-21

申请人： Carlton B. Morgan

发明人： Carlton B. Morgan

IPC分类号： A61N1/39

CPC分类号： A61N1/3931

摘要： A defibrillator and electrode system that gives the user a visible and/or audible indication of the condition of the electrodes and other parts of the defibrillator system prior to deployment of the electrodes and use of the defibrillator. In a preferred embodiment of the method of this invention, a patient simulation and analyze circuit within the defibrillator periodically tests the condition of the system and provides the user with a visual indication of the system's condition.

摘要翻译： 除颤器和电极系统，其在部署电极和使用除颤器之前向用户提供电极和除颤器系统的其他部分的状况的可见和/或可听见的指示。 在本发明方法的优选实施例中，除颤器内的患者模拟和分析电路周期性地测试系统的状况并向用户提供系统状况的视觉指示。