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公开(公告)号：US08640711B2
公开(公告)日：2014-02-04
申请号：US12964678
申请日：2010-12-09
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.
摘要翻译： 在可逆性慢性阻塞性肺疾病如哮喘发作的急性发作期间治疗肺的方法。 该方法包括将能量传递到气道的气道壁，使得气道的直径增加。 在哮喘发作之前，期间或之后，能量可能转移到气道壁。 能量可以以足以临时或永久地增加气道直径的量来转移。 该方法可以在气道打开，关闭或部分关闭时进行。
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公开(公告)号：US07938123B2
公开(公告)日：2011-05-10
申请号：US12325985
申请日：2008-12-01
IPC分类号： A61B19/00
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： A method for decreasing responsiveness or decreasing resistance to airflow of airways involves the transfer of energy to or from the airway walls to prevent or reduce airway constriction and other symptoms of lung diseases. The treatment reduces the ability of the airways to contract during an acute narrowing of the airways, reduces mucus plugging of the airways, and/or increases the airway diameter. The methods according to the present invention provide a longer duration and/or more effective treatment for lung diseases than currently used drug treatments, and obviate patient compliance issues.
摘要翻译： 降低呼吸道反应性或降低气道阻力的方法涉及将能量传递到气道壁或从气道壁传递，以防止或减少气道收缩和肺部疾病的其他症状。 该治疗降低了在气道急性变窄期间气道收缩的能力，减少气道的粘液堵塞和/或增加气道直径。 根据本发明的方法提供比目前使用的药物治疗更长的持续时间和/或更有效的肺部疾病治疗，并且消除患者依从性问题。
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公开(公告)号：US07921855B2
公开(公告)日：2011-04-12
申请号：US11609242
申请日：2006-12-11
IPC分类号： A61B19/00
CPC分类号： A61N5/00 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2090/3614 , A61M25/0043 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403
摘要： A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.
摘要翻译： 在可逆性慢性阻塞性肺疾病如哮喘发作的急性发作期间治疗肺的方法。 该方法包括将能量传递到气道的气道壁，使得气道的直径增加。 在哮喘发作之前，期间或之后，能量可能转移到气道壁。 能量可以以足以临时或永久地增加气道直径的量来转移。 该方法可以在气道打开，关闭或部分关闭时进行。
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公开(公告)号：US07770584B2
公开(公告)日：2010-08-10
申请号：US12328596
申请日：2008-12-04
IPC分类号： A61B19/00
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： Methods of increasing gas exchange performed by the lung by damaging lung cells, damaging tissue, causing trauma, and/or destroying airway smooth muscle tone with an apparatus inserted into an airway of the lung. The damaging of lung cells, damaging tissue, causing trauma, and destroying airway smooth muscle tone with the apparatus may be any one of or combinations of the following: heating the airway; cooling the airway; delivering a liquid to the airway; delivering a gas to the airway; puncturing the airway; tearing the airway; cutting the airway; applying ultrasound to the airway; and applying ionizing radiation to the airway.
摘要翻译： 通过用插入到肺的气道中的装置来增加由肺损伤肺细胞，损伤组织，引起创伤和/或破坏气道平滑肌张力的气体交换的方法。 肺部细胞的破坏，损伤组织，引起创伤，以及用该装置破坏气道平滑肌张力可以是以下任一种或组合：加热气道; 冷气道 向气道输送液体; 向气道输送气体; 刺穿气道; 撕裂气道; 切断气道; 将超声波应用于气道; 并向气道施加电离辐射。
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公开(公告)号：US20090143776A1
公开(公告)日：2009-06-04
申请号：US12325985
申请日：2008-12-01
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： A method for decreasing responsiveness or decreasing resistance to airflow of airways involves the transfer of energy to or from the airway walls to prevent or reduce airway constriction and other symptoms of lung diseases. The treatment reduces the ability of the airways to contract during an acute narrowing of the airways, reduces mucus plugging of the airways, and/or increases the airway diameter. The methods according to the present invention provide a longer duration and/or more effective treatment for lung diseases than currently used drug treatments, and obviate patient compliance issues.
摘要翻译： 降低呼吸道反应性或降低气道阻力的方法涉及将能量传递到气道壁或从气道壁传递，以防止或减少气道收缩和肺部疾病的其他症状。 该治疗降低了在气道急性变窄期间气道收缩的能力，减少气道的粘液堵塞和/或增加气道直径。 根据本发明的方法提供比目前使用的药物治疗更长的持续时间和/或更有效的肺部疾病治疗，并且消除患者依从性问题。
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公开(公告)号：US20090143705A1
公开(公告)日：2009-06-04
申请号：US12328582
申请日：2008-12-04
IPC分类号： A61N7/02
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： Methods of increasing gas exchange performed by the lung by damaging lung cells, damaging tissue, causing trauma, and/or destroying airway smooth muscle tone with an apparatus inserted into an airway of the lung. The damaging of lung cells, damaging tissue, causing trauma, and destroying airway smooth muscle tone with the apparatus may be any one of or combinations of the following: heating the airway; cooling the airway; delivering a liquid to the airway; delivering a gas to the airway; puncturing the airway; tearing the airway; cutting the airway; applying ultrasound to the airway; and applying ionizing radiation to the airway.
摘要翻译： 通过用插入到肺的气道中的装置来增加由肺损伤肺细胞，损伤组织，引起创伤和/或破坏气道平滑肌张力的气体交换的方法。 肺部细胞的破坏，损伤组织，引起创伤，以及用该装置破坏气道平滑肌张力可以是以下任一种或组合：加热气道; 冷气道 向气道输送液体; 向气道输送气体; 刺穿气道; 撕裂气道; 切断气道; 将超声波应用于气道; 并向气道施加电离辐射。
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公开(公告)号：US08161978B2
公开(公告)日：2012-04-24
申请号：US12727156
申请日：2010-03-18
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.
摘要翻译： 在可逆性慢性阻塞性肺疾病如哮喘发作的急性发作期间治疗肺的方法。 该方法包括将能量传递到气道的气道壁，使得气道的直径增加。 在哮喘发作之前，期间或之后，能量可能转移到气道壁。 能量可以以足以临时或永久地增加气道直径的量来转移。 该方法可以在气道打开，关闭或部分关闭时进行。
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公开(公告)号：US08584681B2
公开(公告)日：2013-11-19
申请号：US12765704
申请日：2010-04-22
CPC分类号： A61N5/00 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2090/3614 , A61M25/0043 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403
摘要： A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.
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公开(公告)号：US08267094B2
公开(公告)日：2012-09-18
申请号：US12328582
申请日：2008-12-04
IPC分类号： A61B19/00
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： Methods of increasing gas exchange performed by the lung by damaging lung cells, damaging tissue, causing trauma, and/or destroying airway smooth muscle tone with an apparatus inserted into an airway of the lung. The damaging of lung cells, damaging tissue, causing trauma, and destroying airway smooth muscle tone with the apparatus may be any one of or combinations of the following: heating the airway; cooling the airway; delivering a liquid to the airway; delivering a gas to the airway; puncturing the airway; tearing the airway; cutting the airway; applying ultrasound to the airway; and applying ionizing radiation to the airway.
摘要翻译： 通过用插入到肺的气道中的装置来增加由肺损伤肺细胞，损伤组织，引起创伤和/或破坏气道平滑肌张力的气体交换的方法。 肺部细胞的破坏，损伤组织，引起创伤，以及用该装置破坏气道平滑肌张力可以是以下任一种或组合：加热气道; 冷气道 向气道输送液体; 向气道输送气体; 刺穿气道; 撕裂气道; 切断气道; 将超声波应用于气道; 并向气道施加电离辐射。
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公开(公告)号：US09199091B2
公开(公告)日：2015-12-01
申请号：US12725576
申请日：2010-03-17
申请人： Christopher J. Danek , William J. Wizeman , Timothy R. Dalbec , Glendon E. French , Michael D. Laufer
发明人： Christopher J. Danek , William J. Wizeman , Timothy R. Dalbec , Glendon E. French , Michael D. Laufer
IPC分类号： A61B18/18 , A61N1/378 , A61B18/12 , A61N1/06 , A61N1/40 , A61N1/36 , A61B18/14 , A61B19/00 , A61B17/00 , A61B18/00
CPC分类号： A61B18/1492 , A61B1/00045 , A61B1/04 , A61B1/2676 , A61B6/032 , A61B6/037 , A61B8/08 , A61B18/1233 , A61B34/20 , A61B34/25 , A61B90/361 , A61B2017/00119 , A61B2018/00214 , A61B2018/00267 , A61B2018/00541 , A61B2018/00678 , A61B2018/00702 , A61B2018/00791 , A61B2018/00898 , A61B2018/00904 , A61B2018/1475 , A61B2034/104 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/2072 , A61B2090/309 , A61B2090/365 , A61B2090/367 , A61B2090/374 , A61B2576/02 , A61N1/06 , A61N1/3601 , A61N1/378 , A61N1/403
摘要： Methods for treating a network of organs including generating a map of at least a portion of the network of organs using a rendering system; selecting at least one treatment location within the luminal passageway of the network of organs; and applying an energy therapy to the treatment location to treat the smooth muscle tissue, where the energy therapy applied to the respective treatment location is defined by a plurality of parameters that are associated with a map. Such a system allows for historical or ideal treatment parameters to be identified, visually or otherwise to actual treatment locations. Also, control systems and methods for delivery of energy that may include control algorithms that prevent energy delivery if a fault is detected and may provide energy delivery to produce a substantially constant temperature at a delivery site. In some embodiments, the control systems and methods may be used to control the delivery of energy, such as radiofrequency energy, to body tissue, such as lung tissue.
摘要翻译： 用于治疗器官网络的方法，包括使用再现系统生成器官网络的至少一部分的地图; 在器官网络的管腔通道内选择至少一个治疗位置; 以及将能量疗法应用于治疗位置以治疗平滑肌组织，其中施加到相应治疗位置的能量疗法由与地图相关联的多个参数定义。 这样的系统允许将历史或理想的治疗参数在视觉上或其他方面被识别到实际的治疗位置。 此外，用于递送能量的控制系统和方法可以包括如果检测到故障时防止能量传递的控制算法，并且可以提供能量传递以在输送部位产生基本上恒定的温度。 在一些实施例中，控制系统和方法可用于控制诸如射频能量的能量传递到诸如肺组织的身体组织。
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