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公开(公告)号：US07740017B2
公开(公告)日：2010-06-22
申请号：US11117905
申请日：2005-04-29
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.
摘要翻译： 在可逆性慢性阻塞性肺疾病如哮喘发作的急性发作期间治疗肺的方法。 该方法包括将能量传递到气道的气道壁，使得气道的直径增加。 在哮喘发作之前，期间或之后，能量可能转移到气道壁。 能量可以以足以临时或永久地增加气道直径的量来转移。 该方法可以在气道打开，关闭或部分关闭时进行。
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公开(公告)号：US20090143776A1
公开(公告)日：2009-06-04
申请号：US12325985
申请日：2008-12-01
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： A method for decreasing responsiveness or decreasing resistance to airflow of airways involves the transfer of energy to or from the airway walls to prevent or reduce airway constriction and other symptoms of lung diseases. The treatment reduces the ability of the airways to contract during an acute narrowing of the airways, reduces mucus plugging of the airways, and/or increases the airway diameter. The methods according to the present invention provide a longer duration and/or more effective treatment for lung diseases than currently used drug treatments, and obviate patient compliance issues.
摘要翻译： 降低呼吸道反应性或降低气道阻力的方法涉及将能量传递到气道壁或从气道壁传递，以防止或减少气道收缩和肺部疾病的其他症状。 该治疗降低了在气道急性变窄期间气道收缩的能力，减少气道的粘液堵塞和/或增加气道直径。 根据本发明的方法提供比目前使用的药物治疗更长的持续时间和/或更有效的肺部疾病治疗，并且消除患者依从性问题。
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公开(公告)号：US20090143705A1
公开(公告)日：2009-06-04
申请号：US12328582
申请日：2008-12-04
IPC分类号： A61N7/02
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： Methods of increasing gas exchange performed by the lung by damaging lung cells, damaging tissue, causing trauma, and/or destroying airway smooth muscle tone with an apparatus inserted into an airway of the lung. The damaging of lung cells, damaging tissue, causing trauma, and destroying airway smooth muscle tone with the apparatus may be any one of or combinations of the following: heating the airway; cooling the airway; delivering a liquid to the airway; delivering a gas to the airway; puncturing the airway; tearing the airway; cutting the airway; applying ultrasound to the airway; and applying ionizing radiation to the airway.
摘要翻译： 通过用插入到肺的气道中的装置来增加由肺损伤肺细胞，损伤组织，引起创伤和/或破坏气道平滑肌张力的气体交换的方法。 肺部细胞的破坏，损伤组织，引起创伤，以及用该装置破坏气道平滑肌张力可以是以下任一种或组合：加热气道; 冷气道 向气道输送液体; 向气道输送气体; 刺穿气道; 撕裂气道; 切断气道; 将超声波应用于气道; 并向气道施加电离辐射。
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公开(公告)号：US20130035747A1
公开(公告)日：2013-02-07
申请号：US13557518
申请日：2012-07-25
申请人： Christopher J. DANEK , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly M. Shriner , William J. Wizeman
发明人： Christopher J. DANEK , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly M. Shriner , William J. Wizeman
IPC分类号： A61F7/12
CPC分类号： A61B1/00085 , A61B5/053 , A61B5/0538 , A61B5/08 , A61B5/0809 , A61B5/1076 , A61B5/411 , A61B5/4519 , A61B5/4836 , A61B5/4878 , A61B5/6853 , A61B5/6858 , A61B10/04 , A61B18/06 , A61B18/14 , A61B18/1492 , A61B18/18 , A61B2010/045 , A61B2017/00106 , A61B2017/00809 , A61B2018/00214 , A61B2018/00541 , A61B2018/00773 , A61B2018/00875 , A61B2018/00898 , A61B2018/1472 , A61B2090/061 , A61B2090/064 , A61N5/1001
摘要： This relates to treating airways in a lung to decrease asthmatic symptoms. The also includes steps of measuring a parameter of an airway at a plurality of locations in a lung, identifying at least one treatment site from at least one of the plurality of locations based on the parameter, and applying energy to the treatment site to reduce the ability of the site to narrow.
摘要翻译： 这涉及治疗肺中的气道以减少哮喘症状。 还包括测量肺中多个位置处的气道参数的步骤，基于参数从多个位置中的至少一个位置识别至少一个治疗部位，并将能量施加到治疗部位以减少 网站的能力缩小。
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公开(公告)号：US08161978B2
公开(公告)日：2012-04-24
申请号：US12727156
申请日：2010-03-18
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.
摘要翻译： 在可逆性慢性阻塞性肺疾病如哮喘发作的急性发作期间治疗肺的方法。 该方法包括将能量传递到气道的气道壁，使得气道的直径增加。 在哮喘发作之前，期间或之后，能量可能转移到气道壁。 能量可以以足以临时或永久地增加气道直径的量来转移。 该方法可以在气道打开，关闭或部分关闭时进行。
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公开(公告)号：US08640711B2
公开(公告)日：2014-02-04
申请号：US12964678
申请日：2010-12-09
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.
摘要翻译： 在可逆性慢性阻塞性肺疾病如哮喘发作的急性发作期间治疗肺的方法。 该方法包括将能量传递到气道的气道壁，使得气道的直径增加。 在哮喘发作之前，期间或之后，能量可能转移到气道壁。 能量可以以足以临时或永久地增加气道直径的量来转移。 该方法可以在气道打开，关闭或部分关闭时进行。
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7.发明授权Methods of evaluating individuals having reversible obstructive pulmonary disease 有权评估具有可逆性阻塞性肺疾病的个体的方法公开(公告)号：US08464723B2
公开(公告)日：2013-06-18
申请号：US13171345
申请日：2011-06-28
申请人： Christopher J. Danek , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly Shriner , William J. Wizeman
发明人： Christopher J. Danek , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly Shriner , William J. Wizeman
CPC分类号： A61B18/00 , A61B17/22004 , A61B18/08 , A61B18/14 , A61B18/1492 , A61B2017/00115 , A61B2017/00292 , A61B2017/003 , A61B2017/22062 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/044 , A61B2018/046 , A61B2018/1807 , A61B2090/3614 , A61M25/0043 , A61M29/00 , A61M2025/0096 , A61M2210/1039 , A61N5/0601
摘要： This relates to treating an asthmatic lung and more particularly, relates to advancing a treatment device into the lung and treating the lung with the device. This also includes additional steps of treating the airway wall, applying energy or heat to the airway wall in an asthmatic lung.
摘要翻译： 这涉及治疗哮喘肺，更具体地涉及将治疗装置推进到肺中并用装置治疗肺。 这还包括治疗气道壁，向哮喘肺中的气道壁施加能量或热量的附加步骤。
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公开(公告)号：US08181656B2
公开(公告)日：2012-05-22
申请号：US11361564
申请日：2006-02-23
申请人： Christopher J. Danek , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly M. Shriner
发明人： Christopher J. Danek , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly M. Shriner
IPC分类号： A61B19/00
CPC分类号： A61B17/24 , A61B17/22004 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/1492 , A61B18/18 , A61B2017/00115 , A61B2017/00292 , A61B2017/003 , A61B2017/22062 , A61B2017/242 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/044 , A61B2018/046 , A61B2018/1807 , A61B2090/3614 , A61M25/0043 , A61M29/00 , A61M2025/0096 , A61M2210/1039 , A61N1/3601 , A61N5/0601
摘要： This relates to treating an asthmatic lung and more particularly, relates to advancing a treatment device into the lung and treating the lung with the device. This also includes additional steps of treating the airway wall, applying energy or heat to the airway wall in an asthmatic lung.
摘要翻译： 这涉及治疗哮喘肺，更具体地涉及将治疗装置推进到肺中并用装置治疗肺。 这还包括治疗气道壁，向哮喘肺中的气道壁施加能量或热量的附加步骤。
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公开(公告)号：US07938123B2
公开(公告)日：2011-05-10
申请号：US12325985
申请日：2008-12-01
IPC分类号： A61B19/00
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： A method for decreasing responsiveness or decreasing resistance to airflow of airways involves the transfer of energy to or from the airway walls to prevent or reduce airway constriction and other symptoms of lung diseases. The treatment reduces the ability of the airways to contract during an acute narrowing of the airways, reduces mucus plugging of the airways, and/or increases the airway diameter. The methods according to the present invention provide a longer duration and/or more effective treatment for lung diseases than currently used drug treatments, and obviate patient compliance issues.
摘要翻译： 降低呼吸道反应性或降低气道阻力的方法涉及将能量传递到气道壁或从气道壁传递，以防止或减少气道收缩和肺部疾病的其他症状。 该治疗降低了在气道急性变窄期间气道收缩的能力，减少气道的粘液堵塞和/或增加气道直径。 根据本发明的方法提供比目前使用的药物治疗更长的持续时间和/或更有效的肺部疾病治疗，并且消除患者依从性问题。
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公开(公告)号：US07921855B2
公开(公告)日：2011-04-12
申请号：US11609242
申请日：2006-12-11
IPC分类号： A61B19/00
CPC分类号： A61N5/00 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2090/3614 , A61M25/0043 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403
摘要： A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.
摘要翻译： 在可逆性慢性阻塞性肺疾病如哮喘发作的急性发作期间治疗肺的方法。 该方法包括将能量传递到气道的气道壁，使得气道的直径增加。 在哮喘发作之前，期间或之后，能量可能转移到气道壁。 能量可以以足以临时或永久地增加气道直径的量来转移。 该方法可以在气道打开，关闭或部分关闭时进行。
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