摘要:
This invention provides for certain naphthalenylimidazo compounds, their pharmaceutical formulations, and their use as positive inotropic agents, bronchodilators, vasodilators, and anticoagulants.
摘要:
The invention relates to a medical retrieval device with a basket that has at least one leg that is frangible (i.e., easily breakable) and/or able to dissociate from at least one other leg upon the application of a predetermined force to the basket. The invention allows an operator to release captured material (e.g., a stone) from the basket when the device is still inserted in the body. In an embodiment, the basket legs associate by a magnetic interaction that can be overcome by applying a predetermined force to the basket. In another embodiment, at least a portion of at least one basket leg is made from, or coated with, a substance that is adhesive or that joins at least two legs together when the substance is solid but which melts, dissolves or weakens upon the application of an electrical, thermal or chemical change. In yet another embodiment, the invention provides a basket with at least two legs that are joined together by a joining member that can break, or from which one or more legs can dissociate, upon the application of a predetermined force. In yet another embodiment, the invention provides a basket with at least two legs that are joined together by a joining member by means of at least one shear pin that can break upon the application of a predetermined force.
摘要:
Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.
摘要:
Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. The catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.
摘要:
The present invention is directed to features and aspects of an in-vivo visualization system that comprises a catheter having an access port leading to an interior lumen through which an image transmission member is routed, and an endoscope having an access port leading to an interior lumen through which the catheter is routed. The catheter and endoscope are connected by an endoscope attachment device such that a handle of the catheter is mounted distal of the endoscope access port and the catheter access port is distal to the mounted position.
摘要:
In one embodiment, an endoscope includes an elongate member having a proximal end portion and a distal end portion. The distal end portion is configured to be inserted into a body lumen. An electrical component is disposed within the distal end portion of the elongate member and configured to produce a signal. An elongate conductive mechanical component has a proximal end portion and a distal and portion. The distal end portion of the elongate conductive mechanical component is electrically coupled to the electrical component and configured to conduct the signal or electrical power from/to the electrical component to/from the proximal end portion of the elongate conductive mechanical component.
摘要:
A method according to an embodiment of the invention includes inserting an endoscope at least partially into a body lumen. At least a portion of the body lumen is illuminated at a first wavelength. The portion of the body lumen is illuminated at a second wavelength different than the first wavelength. A characteristic of an area of interest when the portion of the body lumen is illuminated at the first wavelength is compared with the characteristic of the area of interest when the portion of the body lumen is illuminated at the second wavelength. A medical device or treatment parameter is selected to treat the area of interest based on the comparing. In some embodiments, the body lumen is a ureter. In such an embodiment, a composition of a kidney stone within the ureter can be identified.
摘要:
The present invention provides (8.beta.)-N-substituted cyclo or bicycloalkyl-6-(substituted)-ergoline-8-carboxamides useful for occupying 5HT.sub.2 or 5HT.sub.1.sbsb.c receptors in mammals. The invention also provides methods for treating a variety of disorders and conditions related to or affecting these receptors as well as pharmaceutical formulations of the compounds of the invention.
摘要:
This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.
摘要:
This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.