公开(公告)号：US20240196933A1

公开(公告)日：2024-06-20

申请号：US18554927

申请日：2022-04-12

Applicant: DSM IP ASSETS B.V.

Inventor： Maik KINDERMANN ,  Ulla LETINOIS ,  René Tobias STEMMLER ,  Nicola WALKER ,  Luis Fernando MONTEIRO TAMASSIA

IPC: A23K20/111 ,  A23K20/105 ,  A23K50/10

CPC classification number: A23K20/111 ,  A23K20/105 ,  A23K50/10

Abstract: The present invention relates to the field of reduction of methane emission in ruminants. Particularly, it relates to the administration of gossypol and a methane inhibitor to a ruminant for reducing the production of methane emanating from the digestive activities of said ruminant.

公开(公告)号：US20200308090A1

公开(公告)日：2020-10-01

申请号：US16954671

申请日：2018-12-11

Applicant: DSM IP ASSETS B.V.

Inventor： Marcel JORAY ,  René Tobias STEMMLER

IPC: C07C45/65 ,  C07C67/347

Abstract: The present invention relates to the manufacturing of a process of alkyl 2-acetyl-5,9,13-trimethyltetradeca-4,8,12-trienoates and alkyl 2-acetyl-9,13-di-methyl-5-methylenetetradeca-8,12-dienoate as well as 6,10,14-trimethylpenta-deca-5,9,13-trien-2-one and 10,14-dimethyl-6-methylenepentadeca-9,13-dien-2-5 one and 6,10,14-trimethylpentadecan-2-one.

公开(公告)号：US20180170886A1

公开(公告)日：2018-06-21

申请号：US15571113

申请日：2016-05-12

Applicant: DSM IP ASSETS B.V.

Inventor： Nadine GREINER ,  Sandro SCHMID ,  René Tobias STEMMLER

IPC: C07D251/24 ,  C07D251/20 ,  C07B49/00 ,  C07B63/00

CPC classification number: C07D251/24 ,  C07B49/00 ,  C07B63/00 ,  C07D251/20 ,  C07F3/02

Abstract: The invention relates to an improved process for the manufacture of bis-resorcinyl triazines of formula (I) wherein R1 is a C1C18alkyl group or C2-C18alkenyl group as well as the respective alkyl substituted bis-resorcinyl derivatives of formula (II) wherein R1 is a C1-C18alkyl group or C2-C18alkenyl group and R2 and R3 are independently of each other a C1-C18alkyl group or a C2-C18alkenyl group.

公开(公告)号：US20160185702A1

公开(公告)日：2016-06-30

申请号：US14652362

申请日：2013-12-18

Applicant: DSM IP ASSETS B.V.

Inventor： Werner BONRATH ,  Thomas NETSCHER ,  Jonathan Alan MEDLOCK ,  René Tobias STEMMLER ,  Gerardus Karel Maria VERZIJL ,  Andreas Hendrikus Maria DE VRIES

IPC: C07C45/67 ,  C07C45/62

CPC classification number: C07C45/67 ,  C07B2200/07 ,  C07C45/62 ,  C07C49/04 ,  C07C47/02

Abstract: The present invention relates to a process of manufacturing compound having stereogenic centres from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centres. The process involves an asymmetric hydrogenation and an isomerization step. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.

Abstract translation: 本发明涉及由具有前手性双键的不饱和化合物的E / Z异构体的混合物制造具有立体中心化合物的方法。 氢化产物在立体中心处具有特定的所需构型。 该方法包括不对称氢化和异构化步骤。 该方法非常有利，因为它以有效的方式从起始产物的立体异构体的混合物形成所需的手性产物。

公开(公告)号：US20150321987A1

公开(公告)日：2015-11-12

申请号：US14652286

申请日：2013-12-18

Applicant: DSM IP ASSETS B.V.

Inventor： René Tobias STEMMLER ,  Nadine GREINER ,  Angela WILDERMANN

IPC: C07C45/67 ,  C07C29/56 ,  C07C33/02 ,  C07C49/203

CPC classification number: C07C43/313 ,  C07B2200/09 ,  C07C29/56 ,  C07C33/02 ,  C07C45/67 ,  C07C49/203

Abstract: The present invention relates to a process of a cis/trans isomerization of an unsaturated compound A being selected from the group consisting of unsaturated ketones, unsaturated ketals, unsaturated aldehydes, unsaturated acetals, unsaturated carboxylic acids, esters of an unsaturated carboxylic acid and amides of an unsaturated carboxylic acid using nitrogen monoxide as cis/trans isomerization catalyst. It has been observed that the isomerization is very efficient and fast.

Abstract translation: 本发明涉及不饱和化合物A的顺式/反式异构化方法，其选自不饱和酮，不饱和缩酮，不饱和醛，不饱和缩醛，不饱和羧酸，不饱和羧酸的酯和酰胺的酰胺 使用一氧化氮作为顺/反异构化催化剂的不饱和羧酸。 已经观察到异构化非常有效和快速。