公开(公告)号：US20060241709A1

公开(公告)日：2006-10-26

申请号：US11349540

申请日：2006-02-07

申请人： Orhan Soykan ,  Timothy Robinson ,  James Carney ,  Tara Nahey ,  Cygni Chan

发明人： Orhan Soykan ,  Timothy Robinson ,  James Carney ,  Tara Nahey ,  Cygni Chan

IPC分类号： A61N1/362

CPC分类号： A61B5/14546 ,  A61B5/053 ,  A61B5/1107 ,  A61B5/1451 ,  A61B5/14542 ,  A61B5/1473 ,  A61B5/4519 ,  A61B5/686 ,  A61B5/7278 ,  A61B2562/0219 ,  A61M5/14276 ,  A61M5/1723 ,  A61N1/36135 ,  A61N1/36167 ,  A61N1/36557

摘要： In general, the invention is directed to methods and devices for determining an ion concentration in the extracellular fluid of a patient. As examples, the ion may be one or more of potassium, sodium, chloride, or calcium. A system includes an electrode deployed in or near a tissue, such as a skeletal muscle, of the patient. A pulse generator supplies one or more stimulations to the tissue, and a sensor, such as an accelerometer, detects the response of the tissue to the stimulations. A processor determines a concentration of ions in the extracellular fluid as a function of the response. The system may detect an ion imbalance based upon the determined concentration of ions.

摘要翻译： 通常，本发明涉及用于确定患者的细胞外液中的离子浓度的方法和装置。 作为实例，离子可以是钾，钠，氯或钙中的一种或多种。 系统包括部署在患者的组织（例如骨骼肌）中或附近的电极。 脉冲发生器向组织提供一个或多个刺激，并且诸如加速度计的传感器检测组织对刺激的响应。 处理器确定细胞外液中的离子浓度作为响应的函数。 该系统可以基于确定的离子浓度检测离子不平衡。

公开(公告)号：US20060224326A1

公开(公告)日：2006-10-05

申请号：US11096434

申请日：2005-03-31

申请人： John St. Ores ,  Sarah Audet ,  James Carney ,  Janell Gottesman ,  Adrianus Donders ,  Michael Ujhelyi

发明人： John St. Ores ,  Sarah Audet ,  James Carney ,  Janell Gottesman ,  Adrianus Donders ,  Michael Ujhelyi

IPC分类号： G06F19/00

CPC分类号： G06Q50/24 ,  G16H10/20

摘要： A data collection system includes remote, implantable sensors for monitoring one or more patient parameters, collecting and processing data from those sensors and utilizing that data in the performance of a clinical study of a drug or other pharmacological agent. The system assists with preparation of a protocol for a clinical trial; presentation of that protocol; assuring compliance with the protocol; and generating useful results from data collected via the system and externally for presentation to an approval forum.

公开(公告)号：US20060122864A1

公开(公告)日：2006-06-08

申请号：US11038835

申请日：2005-01-20

申请人： Janell Gottesman ,  H. Markowitz ,  James Willenbring ,  Christopher Manrodt ,  John Van Danacker ,  John Burnes ,  John Rueter ,  David Dvorak ,  Sarah Audet ,  James Carney ,  Gerard Hill

发明人： Janell Gottesman ,  H. Markowitz ,  James Willenbring ,  Christopher Manrodt ,  John Van Danacker ,  John Burnes ,  John Rueter ,  David Dvorak ,  Sarah Audet ,  James Carney ,  Gerard Hill

IPC分类号： G06Q10/00 ,  A61B5/00

CPC分类号： G06F19/3418 ,  G06Q50/22 ,  G16H80/00

摘要： An intelligent patient management system collects data from a variety of sources, processes that information, and provides relevant information to an appropriate caregiver in context at the proper time. The system has multiple information sources available from which to gather additional information based upon conclusions drawn or issues identified from the patient data.

摘要翻译： 智能患者管理系统从各种来源收集数据，处理该信息，并在适当的时候向适当的照顾者提供相关信息。 该系统具有多种信息来源，可根据患者数据识别的结论或问题收集附加信息。

公开(公告)号：US20060217771A1

公开(公告)日：2006-09-28

申请号：US11349058

申请日：2006-02-07

申请人： Orhan Soykan ,  Timothy Robinson ,  James Carney

发明人： Orhan Soykan ,  Timothy Robinson ,  James Carney

IPC分类号： A61N1/00

CPC分类号： A61B5/14546 ,  A61B5/053 ,  A61B5/1107 ,  A61B5/1451 ,  A61B5/14542 ,  A61B5/1473 ,  A61B5/4519 ,  A61B5/686 ,  A61B5/7278 ,  A61B2562/0219 ,  A61M5/14276 ,  A61M5/1723 ,  A61N1/36135 ,  A61N1/36167 ,  A61N1/36557

摘要： In general, the invention is directed to methods and devices for determining a potassium ion concentration in the extracellular fluid of a patient. A system includes an electrode deployed in or near a tissue, such as a skeletal muscle, of the patient. A pulse generator supplies one or more stimulations to the tissue, and a sensor, such as an accelerometer, detects the response of the tissue to the stimulations. A processor determines a concentration of potassium ions in the extracellular fluid as a function of the response.

摘要翻译： 通常，本发明涉及用于测定患者细胞外液中的钾离子浓度的方法和装置。 系统包括部署在患者的组织（例如骨骼肌）中或附近的电极。 脉冲发生器向组织提供一个或多个刺激，并且诸如加速度计的传感器检测组织对刺激的响应。 处理器确定细胞外液中钾离子的浓度作为反应的函数。

公开(公告)号：US20050090761A1

公开(公告)日：2005-04-28

申请号：US10692251

申请日：2003-10-23

申请人： James Carney

发明人： James Carney

IPC分类号： A61B5/00

CPC分类号： A61B5/01

摘要： A method and system for determining vulnerable plaque in a cardiovascular lumen is disclosed. A guide member is inserted into the cardiovascular lumen. Temperature is sensed from a first position and a second position along the inserted guide member. Vulnerable plaque is determined based on the sensed temperature from the first position and the second position.

摘要翻译： 公开了一种用于确定心血管内腔中脆弱斑块的方法和系统。 引导构件插入心血管内腔。 沿着插入的引导构件从第一位置和第二位置感测温度。 基于来自第一位置和第二位置的感测温度来确定易损斑块。

公开(公告)号：US20050043594A1

公开(公告)日：2005-02-24

申请号：US10920818

申请日：2004-08-17

申请人： David Dinsmoor ,  James Carney

发明人： David Dinsmoor ,  James Carney

IPC分类号： A61K9/22 ,  A61N1/08 ,  A61B5/00 ,  H01H36/00 ,  H01H37/00

CPC分类号： A61N1/08 ,  A61N1/378

摘要： An integrated activation system for an implantable medical device (IMD) sharing a power source, the activation system having a switching circuit and a sensing element coupled to the switching circuit. The switching circuit is configured to gate power from the power source to the IMD. The sensing element is configured to draw current from the power source of less than or equal to about 1 nA during inactivation, enable an operation interval of the switching circuit, and trigger a first state change in the switching circuit. The switching circuit further is configured to gate power to the IMD upon receipt of a pre-determined number of signals from the sensing element.

摘要翻译： 一种用于共享电源的可植入医疗设备（IMD）的集成激活系统，所述激活系统具有切换电路和耦合到所述切换电路的感测元件。 开关电路被配置为将电力从电源门控到IMD。 感测元件被配置为在停用期间从电源抽取小于或等于约1nA的电流，使能开关电路的操作间隔，并触发开关电路中的第一状态变化。 开关电路还被配置为在从感测元件接收到预定数量的信号时对IMD进行栅极电源。