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公开(公告)号：US08945856B2
公开(公告)日：2015-02-03
申请号：US14188784
申请日：2014-02-25
IPC分类号： G01N33/53 , G01N33/569 , G01N33/554 , G01N33/543
CPC分类号： G01N33/56916 , G01N33/5308 , G01N33/54366 , G01N33/554 , G01N33/56911 , G01N33/56983
摘要： A method of biochemical identification by: providing a plurality of capture species bound to one or more substrates and suspected of having one or more biological targets affinity bound to at least one capture species; detecting which capture species contain bound biological targets to generate a binding pattern; and identifying the biological target based on the binding pattern. The capture species are independently selected from the group consisting of antimicrobial peptides, cytotoxic peptides, antibiotics, and combinations thereof. A device having the capture species bound to the substrates. At least two of the capture species are capable of multi-specific binding to one or more biological targets and may have overlapping but not identical affinity properties.
摘要翻译： 生物化学鉴定的方法是：提供与一种或多种底物结合的多种捕获物质，并怀疑具有与至少一种捕获物质结合的一种或多种生物靶标; 检测哪些捕获物种含有结合的生物靶标以产生结合模式; 以及基于所述结合模式识别所述生物学目标。 捕获物种独立地选自抗微生物肽，细胞毒性肽，抗生素及其组合。 具有捕获物质与基底结合的装置。 至少两种捕获物质能够与一种或多种生物靶标进行多特异性结合，并且可以具有重叠但不相同的亲和性质。
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公开(公告)号：US4228419A
公开(公告)日：1980-10-14
申请号：US932264
申请日：1978-08-09
申请人： George P. Anderson
发明人： George P. Anderson
CPC分类号： G08G1/087
摘要： The present system provides a traffic signal control system which will allow moving emergency vehicles to remotely take control of the traffic signals at an intersection. The transmitter part of the system utilizes a microwave transmitter that is mounted on each emergency vehicle, which transmitter emits a pulse coded message which is received by a permanently fixed receiver at each intersection to be controlled. The receiver includes decoding logic to verify that a valid code request has been transmitted by the vehicle. The receiver includes a directional antenna that faces each direction to be controlled which therefore automatically discriminates against signals being received from other directions, and if the appropriate code is received during a predetermined interval of time, the receiver will cause the traffic signals to cycle so that a green or go phase will be directed to the oncoming emergency vehicle and cross traffic will be warned by red signals facing it. After the emergency vehicle has entered the intersection, lack of direct transmission from it will conclude the control after a fixed delay to allow the vehicle time to clear the intersection. The same fixed delay will enable the vehicle to maintain control of the intersection even if it should momentarily lose direct microwave contact because of an intervening large truck or bus.
摘要翻译： 本系统提供了一种交通信号控制系统，该系统将允许移动的紧急车辆在交叉路口远程控制交通信号。 系统的发射机部分使用安装在每个紧急车辆上的微波发射机，该发射机发射脉冲编码消息，该脉冲编码消息由被控制的每个交叉路口处的永久固定的接收机接收。 接收机包括解码逻辑以验证车辆已发送有效的代码请求。 接收机包括定向天线，其面向要控制的每个方向，因此自动识别从其它方向接收的信号，并且如果在预定的时间间隔期间接收到适当的代码，则接收机将使交通信号循环，使得 一个绿色或进入阶段将被引导到即将到来的应急车辆，交叉路口将被面临的红色信号警告。 紧急车辆进入十字路口后，由于缺少直接传输，在一段固定的延时之后可以结束控制，让车辆时间清除十字路口。 相同的固定延迟将使得车辆能够保持交叉路口的控制，即使由于中间大型卡车或公共汽车，它也应该暂时失去直接的微波接触。
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公开(公告)号：US20140187446A1
公开(公告)日：2014-07-03
申请号：US14188784
申请日：2014-02-25
IPC分类号： G01N33/569 , G01N33/543
CPC分类号： G01N33/56916 , G01N33/5308 , G01N33/54366 , G01N33/554 , G01N33/56911 , G01N33/56983
摘要： A method of biochemical identification by: providing a plurality of capture species bound to one or more substrates and suspected of having one or more biological targets affinity bound to at least one capture species; detecting which capture species contain bound biological targets to generate a binding pattern; and identifying the biological target based on the binding pattern. The capture species are independently selected from the group consisting of antimicrobial peptides, cytotoxic peptides, antibiotics, and combinations thereof. A device having the capture species bound to the substrates. At least two of the capture species are capable of multi-specific binding to one or more biological targets and may have overlapping but not identical affinity properties.
摘要翻译： 生物化学鉴定的方法是：提供与一种或多种底物结合的多种捕获物质，并怀疑具有与至少一种捕获物质结合的一种或多种生物靶标; 检测哪些捕获物种含有结合的生物靶标以产生结合模式; 以及基于所述结合模式识别所述生物学目标。 捕获物种独立地选自抗微生物肽，细胞毒性肽，抗生素及其组合。 具有捕获物质与基底结合的装置。 至少两种捕获物质能够与一种或多种生物靶标进行多特异性结合，并且可以具有重叠但不相同的亲和性质。
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公开(公告)号：US08192646B2
公开(公告)日：2012-06-05
申请号：US13229177
申请日：2011-09-09
CPC分类号： B82Y15/00 , G01N33/551 , G01N33/588
摘要： The ionic conjugates include an inorganic particle electrostatically associated with a macromolecule which can interact specifically with predetermined chemical species or biological targets.
摘要翻译： 离子共轭物包括与大分子静电相关的无机颗粒，其可以与预定的化学物质或生物靶相互作用。
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公开(公告)号：US20090272913A1
公开(公告)日：2009-11-05
申请号：US12431784
申请日：2009-04-29
IPC分类号： G01N21/64 , C09K11/02 , C07D471/06
CPC分类号： G01N21/6428 , B82Y20/00 , B82Y30/00 , C07D471/06 , C09K11/06 , C09K2211/1416 , C09K2211/1433 , C09K2211/1466 , G01N2021/6439 , G01N2021/6441 , H05B33/14
摘要： A nanoparticle having a surfactant shell with a hydrophilic outer surface and a hydrophobic inner surface and an organic chromophore and a polymer having aromatic groups within the surfactant shell. A method of making nanoparticles by: emulsifying an aqueous composition of a surfactant and an organic solution of a monomer and an organic chromophore to form micelles of the monomer and the chromophore inside a surfactant shell; and polymerizing the monomer. A method of: reacting a ω-bromoalkyl acid with acryloyl acid lithium salt, and reacting the product with sodium hydride to produce an acryloyloxyalkyl carboxylic acid sodium salt. The compound shown below.
摘要翻译： 具有亲水外表面和疏水性内表面的表面活性剂外壳和有机发色团的纳米颗粒和在表面活性剂外壳内具有芳族基团的聚合物。 一种通过以下方法制备纳米颗粒：将表面活性剂的水性组合物和单体和有机发色团的有机溶液乳化，以在表面活性剂壳内形成单体和发色团的胶束; 并使单体聚合。 一种使ω-溴烷基酸与丙烯酰基锂盐反应并使产物与氢化钠反应产生丙烯酰氧基烷基羧酸钠盐的方法。 化合物如下所示。
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公开(公告)号：US06921496B2
公开(公告)日：2005-07-26
申请号：US09811824
申请日：2001-03-20
IPC分类号： G01N33/566 , G01N33/53 , G01N33/551 , G01N33/58 , C09K11/54 , C12P21/00
CPC分类号： B82Y15/00 , G01N33/551 , G01N33/588
摘要： The ionic conjugates include an inorganic particle electrostatically associated with a macromolecule which can interact specifically with predetermined chemical species or biological targets.
摘要翻译： 离子共轭物包括与大分子静电相关的无机颗粒，其可以与预定的化学物质或生物靶相互作用。
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公开(公告)号：US06713272B2
公开(公告)日：2004-03-30
申请号：US09955023
申请日：2001-09-19
IPC分类号： G01N3353
CPC分类号： G01N33/54393
摘要： A recombinant protein that is a fusion protein containing a protein binding domain and a domain that is post-translationally modified to become lipid-tagged. This molecule has both a domain with highly specific binding capabilities and a domain which is very hydrophobic in nature. This type of molecule can be used to coat hydrophobic surfaces such as polystyrene easily and effectively for use in solid phase binding assays.
摘要翻译： 重组蛋白，其是含有蛋白质结合结构域和翻译后修饰以变成脂质标记的结构域的融合蛋白。 该分子具有具有高度特异性结合能力的结构域和本质上非常疏水的结构域。 这种类型的分子可用于容易且有效地涂覆疏水性表面如聚苯乙烯用于固相结合测定。
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公开(公告)号：US5430813A
公开(公告)日：1995-07-04
申请号：US176572
申请日：1993-12-30
申请人： George P. Anderson , Joel Golden
发明人： George P. Anderson , Joel Golden
CPC分类号： G01N21/648 , G01N21/6428 , G01N21/7703 , G02B6/262 , G01N2021/7736 , G02B6/4203
摘要： A combination tapered V number matching optical fiber probe is disclosed. The combination taper consists of a first short tapered section along the unclad, distal end of an optical fiber. The first short tapered section has a taper angle steeper than the taper angle of the second tapered section also along the unclad, most distal end of the optical fiber. The first short tapered section is adjacent to and proximal to the second tapered section. Proximal to the unclad, combination tapered section of the optical fiber is the cladded portion of the optical fiber. The cladding surrounds the core of the fiber. The optical fiber is used in conjunction with, for example, fluorescence assays as described herein.
摘要翻译： 公开了一种锥形V数匹配光纤探头组合。 组合锥形包括沿着光纤的未包围的远端的第一短锥形部分。 第一短锥形部分的锥角比第二锥形部分的锥角还沿着光纤的未包层的最远端更尖锐。 第一短锥形部分邻近并靠近第二锥形部分。 靠近未包层的光纤的组合锥形部分是光纤的包层部分。 包层围绕着纤维的核心。 光纤与本文所述的荧光测定结合使用。
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公开(公告)号：USD332835S
公开(公告)日：1993-01-26
申请号：US473384
申请日：1990-02-01
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公开(公告)号：US20110319601A1
公开(公告)日：2011-12-29
申请号：US13229177
申请日：2011-09-09
CPC分类号： B82Y15/00 , G01N33/551 , G01N33/588
摘要： The ionic conjugates include an inorganic particle electrostatically associated with a macromolecule which can interact specifically with predetermined chemical species or biological targets.
摘要翻译： 离子共轭物包括与大分子静电相关的无机颗粒，其可以与预定的化学物质或生物靶相互作用。
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