公开(公告)号：US20140255606A1

公开(公告)日：2014-09-11

申请号：US14198776

申请日：2014-03-06

Applicant: David Thompson ,  Jeffrey W. Anthis ,  David Knapp ,  Benjamin Schmiege

Inventor： David Thompson ,  Jeffrey W. Anthis ,  David Knapp ,  Benjamin Schmiege

IPC: C23C16/42

CPC classification number: C23C16/42 ,  C23C16/18 ,  C23C16/34 ,  C23C16/45536 ,  C23C16/45553 ,  H01L21/28518 ,  H01L21/28562 ,  H01L21/76843

Abstract: Described are cobalt-containing films, as well as methods for providing the cobalt-containing films. Certain methods pertain to exposing a substrate surface to a precursor and a co-reactant to provide a cobalt-containing film, the first precursor having a structure represented by: wherein each R is independently C1-C6 substituted or un-substituted alkanes, branched or un-branched alkanes, substituted or un-substituted alkenes, branched or un-branched alkenes, substituted or un-substituted alkynes, branched or un-branched alkynes or substituted or un-substituted aromatics, L is a coordinating ligand comprising a Lewis base.

Abstract translation: 描述的是含钴膜，以及用于提供含钴膜的方法。 某些方法涉及将底物表面暴露于前体和共反应物以提供含钴膜，第一前体具有由以下表示的结构：其中每个R独立地为C 1 -C 6取代或未取代的烷烃，支链或 支链烷烃，取代或未取代的烯烃，支链或非支链烯烃，取代或未取代的炔烃，支链或非支链炔烃或取代或未取代的芳烃，L是包含路易斯碱的配位配体。

公开(公告)号：US20140030436A1

公开(公告)日：2014-01-30

申请号：US13557348

申请日：2012-07-25

Applicant: David Knapp

Inventor： David Knapp

IPC: C23C16/06

CPC classification number: C23C16/18 ,  C07F15/04

Abstract: Provided are precursors and methods of using same to deposit film consisting essentially of nickel. Certain methods comprise providing a substrate surface; exposing the substrate surface to a vapor comprising a precursor having a structure represented, without limitation to specific orientation, by: wherein R1 and R2 are each independently H or any C1-C3 alkyl group, R4 is trimethylsilyl or C1-C3 alkyl, and L is any ligand that does not contain oxygen; and exposing the substrate to a reducing gas to provide a film consisting essentially of nickel on the substrate surface.

Abstract translation: 提供的是使用其沉积基本上由镍组成的膜的前体和方法。 某些方法包括提供基底表面; 将基板表面暴露于包含前体的蒸汽，所述前体具有但不限于特定取向的结构，其中R1和R2各自独立地为H或任何C1-C3烷基，R4为三甲基甲硅烷基或C1-C3烷基，L为 是不含氧的任何配体; 并将衬底暴露于还原气体，以在衬底表面上提供基本上由镍组成的膜。

公开(公告)号：US20090094657A1

公开(公告)日：2009-04-09

申请号：US12245037

申请日：2008-10-03

Applicant: Martin Miller ,  Wen Zhang ,  David Knapp

Inventor： Martin Miller ,  Wen Zhang ,  David Knapp

IPC: H04N7/173

CPC classification number: H04N21/23602 ,  H04J3/0626 ,  H04N21/2383 ,  H04N21/242 ,  H04N21/4342 ,  H04N21/647 ,  H04N21/64792

Abstract: A system for transferring real-time video data over a network comprises a video source, a video encoder for encoding and compressing video data supplied by the video source and a first network interface controller for transmitting compressed video data on the network. Furthermore a second network interface controller for receiving compressed video data from the network, a video decoder for decoding the video data received by the second network interface controller, and an image processor for processing and/or displaying the decoded video data from the video decoder are provided. The network controllers are configured for transmitting and receiving data in a continuous data stream which is synchronized with a clock signal and in a format which prescribes a pulse sequence of individual bit groups of which at least one is used for video data.

Abstract translation: 用于通过网络传送实时视频数据的系统包括视频源，用于编码和压缩由视频源提供的视频数据的视频编码器和用于在网络上发送压缩视频数据的第一网络接口控制器。 此外，用于从网络接收压缩视频数据的第二网络接口控制器，用于解码由第二网络接口控制器接收的视频数据的视频解码器和用于处理和/或显示来自视频解码器的解码视频数据的图像处理器， 提供。 网络控制器被配置为在与时钟信号同步的连续数据流中发送和接收数据，并且以规定至少一个用于视频数据的各个位组的脉冲序列的格式。

公开(公告)号：US20090080462A1

公开(公告)日：2009-03-26

申请号：US12193328

申请日：2008-08-18

Applicant: Rainer P. Mueller ,  Horace C. Ho ,  Patrick Heck ,  David Knapp ,  Kevin Rolfes

Inventor： Rainer P. Mueller ,  Horace C. Ho ,  Patrick Heck ,  David Knapp ,  Kevin Rolfes

IPC: H04L29/06

CPC classification number: H04L47/10 ,  H04L47/18 ,  H04L47/263 ,  H04L47/266 ,  H04L47/30 ,  Y02D50/10

Abstract: A communication system, network, interface, and port architecture are provided for transporting data across a network. The network can be arranged by connecting the ports in a daisy chain fashion to achieve a ring architecture or topology. The network forwards data according to a specific network protocol. A first port forwards frames having a preemptive acknowledge field before the payload. A second port receives these frames, stores them in a frame buffer and modifies the preemptive acknowledge field according to its available frame buffer capacity. Said first port controls its data flow according to the modified preemptive acknowledge field.

Abstract translation: 提供通信系统，网络，接口和端口架构，用于通过网络传输数据。 可以通过以菊花链方式连接端口来实现网络，以实现环形架构或拓扑。 网络根据特定的网络协议转发数据。 第一个端口在有效载荷之前转发具有抢占确认字段的帧。 第二端口接收这些帧，将它们存储在帧缓冲器中，并根据其可用的帧缓冲器容量修改抢占确认字段。 所述第一端口根据修改的抢占确认字段控制其数据流。

公开(公告)号：US20080095190A1

公开(公告)日：2008-04-24

申请号：US11961047

申请日：2007-12-20

Applicant: David Knapp ,  Patrick Heck

Inventor： David Knapp ,  Patrick Heck

IPC: H04J3/16

CPC classification number: H04J3/1682 ,  H04J3/0638 ,  H04J3/12

Abstract: A communication system, network interface, and communication port is provided for interconnecting a network of multimedia devices. The multimedia devices can send streaming and/or non-streaming data across the network. The network accommodates all such types of data and assigns data types to time slots or frame segments within each frame to ensure streaming data maintains its temporal relationship at the receiver consistent with the transmitter. A signaling byte is preferably used to keep track of an amount by which isochronous streaming data occupies a frame segment.

Abstract translation: 提供通信系统，网络接口和通信端口用于互连多媒体设备的网络。 多媒体设备可以通过网络发送流和/或非流数据。 网络容纳所有这些类型的数据，并将数据类型分配给每帧内的时隙或帧段，以确保流数据在接收机处保持其与发射机一致的时间关系。 信令字节优选地用于跟踪同步流数据占据帧段的量。

公开(公告)号：US20070255855A1

公开(公告)日：2007-11-01

申请号：US11676001

申请日：2007-02-16

Applicant: David Knapp ,  Rainer Mueller ,  Horace Ho ,  Patrick Heck ,  Rainer Klos ,  Christian Thiel

Inventor： David Knapp ,  Rainer Mueller ,  Horace Ho ,  Patrick Heck ,  Rainer Klos ,  Christian Thiel

IPC: G06F15/173

CPC classification number: H04J3/0605 ,  H04J3/0647 ,  H04J3/0658 ,  H04J3/1605 ,  H04L12/40006 ,  H04L12/413 ,  H04L12/42 ,  H04L25/4908

Abstract: A communication system, network, interface, and port architecture are provided for transporting different types of data across a network. The network can be arranged by connecting the ports in a daisy-chain fashion to achieve a ring architecture or topology. The network forwards data according to a specific network protocol, and nodes among the network can use a recovered clock from the bitstream to drive the transmitter and create a synchronous network even thought the network can receive Ethernet packets which are typically targeted for an asynchronous network. Non-compliant data, such as Ethernet data, can be sent as packets within a frame structure. The frame is synchronized to Ethernet coding violations used to signal the beginning of each frame, and each packet can be immediately followed by a packet coding violation. The frame and packet coding violations are represented as a sequence of 4B/5B codes that are not valid codes and, therefore, not present as Ethernet encoded data.

Abstract translation: 提供通信系统，网络，接口和端口架构，用于通过网络传输不同类型的数据。 可以通过以菊花链方式连接端口来实现网络，以实现环形架构或拓扑。 网络根据特定网络协议转发数据，网络中的节点可以使用来自比特流的恢复时钟来驱动发射机，并创建一个同步网络，甚至认为网络可以接收通常针对异步网络的以太网分组。 诸如以太网数据之类的不合规数据可以作为帧结构内的分组发送。 帧被同步到以太网编码违例，用于发信号通知每帧的开始，并且每个数据包可能紧随其后的是一个数据包编码违规。 帧和分组编码违例被表示为不是有效代码的4B / 5B代码序列，因此不作为以太网编码数据出现。

公开(公告)号：US20050271068A1

公开(公告)日：2005-12-08

申请号：US10859470

申请日：2004-06-02

Applicant: Herbert Hetzel ,  David Knapp

Inventor： Herbert Hetzel ,  David Knapp

IPC: H04L12/44 ,  H04L12/28 ,  H04L12/43 ,  H04L29/04 ,  H04L12/66

CPC classification number: H04L12/43

Abstract: A communication system, network, interface, and port architecture are provided for transporting different types of data across a network. The network can be arranged by connecting the ports in a daisy chain fashion to achieve a ring architecture or topology. The network forwards data according to a specific network protocol, and any incoming data that follows that protocol will be sent onto the network. If the incoming data protocol does not match the network protocol, then the incoming data is not sent immediately to the network, but instead is sent to an input pin of a device upon the network specifically designed to receive that incoming data. The network, therefore, has ports that support both compliant and non-compliant incoming data, and the devices that produce such data. Examples of non-compliant data include any data which does not time-division multiplex different asynchronous, isochronous, and synchronous data in dedicated channels within each frame, and which have a preamble, coding, frequency, or overall protocol different from that which is established for network transfer.

Abstract translation: 提供通信系统，网络，接口和端口架构，用于跨网络传输不同类型的数据。 可以通过以菊花链方式连接端口来实现网络，以实现环形架构或拓扑。 网络根据特定网络协议转发数据，该协议之后的任何传入数据将被发送到网络上。 如果传入数据协议与网络协议不匹配，则传入的数据不会立即发送到网络，而是在专门设计为接收该传入数据的网络上发送到设备的输入引脚。 因此，该网络具有支持兼容和不符合输入数据的端口以及产生此类数据的设备。 不合规数据的示例包括在每个帧内的专用信道中不对不同异步，同步和同步数据进行时分复用的任何数据，并且具有与建立的不同的前导码，编码，频率或总体协议不同的数据 用于网络传输。

公开(公告)号：US20050169842A1

公开(公告)日：2005-08-04

申请号：US11095429

申请日：2005-03-31

Applicant: David Knapp ,  Brian Berg

Inventor： David Knapp ,  Brian Berg

IPC: A61B6/00 ,  A61B6/03 ,  A61B6/12 ,  A61F2/86 ,  A61L31/18 ,  A61K49/04

CPC classification number: A61F2/86 ,  A61B6/482 ,  A61F2/91 ,  A61L31/18

Abstract: A method for obtaining diagnostic information about a region of a living being, the region having a medical device with a radiopaque portion disposed therein. An X-ray beam having a first energy level in excess of the K-absorption edge of the radiopaque portion of the medical device is directed at the region to obtain a first image information and radiographically locate the medical device within the living being and an X-ray beam having second energy level at or below the K-absorption edge is applied to the region to obtain a second image information.

Abstract translation: 一种用于获得关于生物区域的诊断信息的方法，所述区域具有设置在其中的不透射线部分的医疗装置。 具有超过医疗装置的不透射线部分的K吸收边缘的第一能级的X射线束被引导到该区域以获得第一图像信息，并且将生物体内的医疗装置放射X射线定位，X 将具有在K吸收边缘处或下方的第二能级的射线束施加到该区域以获得第二图像信息。

公开(公告)号：US20050038235A1

公开(公告)日：2005-02-17

申请号：US10881713

申请日：2004-06-30

Applicant: Robert Herrmann ,  David Knapp

Inventor： Robert Herrmann ,  David Knapp

IPC: C07C381/00 ,  C08B37/00 ,  C08B37/16 ,  C07C29/02 ,  C07H5/04 ,  C07K14/00

CPC classification number: C07C381/00 ,  C08B37/00 ,  C08B37/0012

Abstract: A method for producing a S-nitrosylated species is provided. The method comprises: (a) providing a deoxygenated, alkaline aqueous solution comprising a thiol and a nitrite-bearing species; (b) acidifying the solution by adding acid to the solution while concurrently mixing the solution (e.g., by vigorously stirring the solution) to produce the S-nitrosylated species; and (c) isolating the S-nitrosylated species. The nitrite-bearing species can be, for example, an inorganic nitrite, such as an alkali metal nitrite, or an organic nitrite, such as an alkyl nitrite (e.g., ethyl nitrite, amyl nitrite, isobutyl nitrite or t-butyl nitrite). The thiol is preferably a thiol-containing polysaccharide, a thiol-containing lipoprotein, a thiol-containing amino acid or a thiol-containing protein, and more preferably a thiol-containing polysaccharide such as thiolated cyclodextrin. In many preferred embodiments, the S-nitrosylated species is insoluble in the acidified solution, precipitating upon formation. The S-nitrosylated species can be isolated, for example, by a process in which the precipitate is removed from the solution (e.g., by centrifugation) and the aqueous solvent remaining in the precipitate is sublimated (e.g., by freezing the precipitate and subjecting it to a vacuum). The isolated S-nitrosylated product is preferably protected from heat, light, moisture and oxygen.

Abstract translation: 提供了生产S-亚硝基化物质的方法。 该方法包括：（a）提供包含硫醇和含亚硝酸盐的物质的脱氧碱性水溶液; （b）通过向溶液中加入酸来酸化溶液，同时混合溶液（例如通过剧烈搅拌该溶液）以产生S-亚硝基化物质; 和（c）分离S-亚硝基化物质。 含有亚硝酸盐的物质可以是例如无机亚硝酸盐，例如碱金属亚硝酸盐或有机亚硝酸盐，例如亚硝酸烷基酯（例如亚硝酸亚乙酯，亚硝酸戊酯，亚硝酸异丁酯或亚硝酸叔丁酯）。 硫醇优选为含硫醇的多糖，含硫醇的脂蛋白，含巯基的氨基酸或含硫醇的蛋白质，更优选含硫醇的多糖如硫醇化环糊精。 在许多优选实施方案中，S-亚硝基化物质不溶于酸化溶液，在形成时沉淀。 S-亚硝基化物质可以例如通过其中从溶液中除去沉淀物（例如通过离心）并且残留在沉淀物中的水性溶剂升华的方法分离（例如，通过冷冻沉淀物并使其沉淀 到真空）。 分离的S-亚硝基化产物优选保护免受热，光，水分和氧气的影响。

公开(公告)号：US06706274B2

公开(公告)日：2004-03-16

申请号：US09765131

申请日：2001-01-18

Applicant: Robert A. Herrmann ,  David Knapp

Inventor： Robert A. Herrmann ,  David Knapp

IPC: A61F200

CPC classification number: A61K9/0024 ,  A61K31/21 ,  A61K31/53 ,  A61K45/06 ,  A61L27/54 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/114 ,  A61L2300/45 ,  A61L2300/602

Abstract: This invention relates to devices and methods for the local, differential delivery of nitric oxide within the body. The devices include devices having at least two differing nitric oxide donor compounds, such as nitric oxide donor compounds having differing half-lives and nitric oxide donor compounds having different release mechanisms. The devices also include devices having at least two chemically distinct compositions to which nitric oxide donor compounds are adsorbed or attached or within which the donor compounds are disposed. The devices are typically used to increase local nitric oxide concentration in the body upon placement of the medical article at a delivery position on or within a patient. The methods of the present invention include a method of treating an atherosclerotic lesion which comprises: exposing the lesion to a first higher concentration of nitric oxide effective to reduce the number of cells within the lesion; and subsequently exposing the lesion to a second lower concentration of nitric oxide effective to inhibit restenosis. The methods of the present invention also include methods for preferentially providing differing nitric oxide donor compounds within different tissues to effect therapy.

Abstract translation: 本发明涉及用于局部，差异地递送体内一氧化氮的装置和方法。 所述装置包括具有至少两种不同一氧化氮供体化合物的装置，例如具有不同半衰期的一氧化二氮供体化合物和具有不同释放机制的一氧化氮供体化合物。 所述装置还包括具有至少两种化学上不同的组合物的装置，其中一氧化氮供体化合物被吸附或附着，其中配置施主化合物。 该装置通常用于在将医疗用品放置在患者身上或患者内的输送位置时增加身体中的局部一氧化氮浓度。 本发明的方法包括治疗动脉粥样硬化病变的方法，其包括：将病变暴露于第一高浓度的一氧化氮，有效减少损伤内的细胞数; 并随后将病变暴露于有效抑制再狭窄的第二较低浓度的一氧化氮。 本发明的方法还包括优先在不同组织内提供不同的一氧化氮供体化合物以实现治疗的方法。