摘要:
The present invention relates to a novel composition of mycophenolic acid, a salt or a prodrug thereof and to a fixed combination of mycophenolic acid, a salt or a prodrug thereof and rapamycin or a rapamycin derivative.
摘要:
A process for the catalytic gas-phase oxidation of propene or isobutene to acrolein or methacrolein in a tubular fixed bed reactor or catalytically active oxides with a .gtoreq.90% conversion of the initial olefin on a single passage, wherein the temperature of the gases containing the reactants in the direction of flow along the tubes from their entrance until the conversion of the initial olefin is from 30 to 70% is from 360.degree. to 420.degree. C. and is then adjusted to from 360.degree. to 300.degree. C. until the conversion of the initial olefin is from 80 to 90% and is thereafter maintained at from 330.degree. to 390.degree. C. until the gases emerge from the tubes, is described.
摘要:
A large open-center roller bearing consisting of single or multiple outer and inner rings with rollers rolling over races between the rings, wherein one ring can accommodate an ultrasonic probe and the other ring has a contact surface. The object is to provide a bearing that can be simply and reliably tested by ultrasound. One or more contact surfaces (19, 24, and 25) extend around one or more of the outer surfaces of the ring (2 or 3) being tested.
摘要:
The corrosive effect of toothpaste on aluminum is prevented by incorporating in the toothpaste about 0.05% to about 5% by weight of a synthetic alkali metal aluminum silicate zeolite. Toothpaste containing a zeolite of the empirical formula Na.sub.12 (AlO.sub.2).sub.12.(SiO.sub.2).sub.12.27H.sub.2 O is particularly useful.
摘要:
The present invention relates to a novel crystalline anhydrous form of [(5-chlorothiophene-2-ylsulfonylcarbamoyl)-(4-(6-fluoro-7-(methylamino)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)phenyl)amide, potassium salt, and its use in the treatment or prevention of a condition or a disorder with platelet ADP receptor inhibition, in particular, P2Y12 inhibition, in animals, particularly humans. It also relates processes for making such a novel crystalline form. The present invention also relates to a solid, oral formulation of this novel crystalline form, its preparation and use thereof.
摘要:
The present invention relates to a pharmaceutical oral fixed dose combination comprising a) a therapeutically effective amount of Aliskiren, or a pharmaceutically acceptable salt thereof, b) a therapeutically effective amount of Valsartan, or a pharmaceutically acceptable salt thereof, wherein the pharmaceutical oral fixed dose combination shows an in vitro dissolution of component (a) of 60% or less after 10 minutes and 95% or less after 20 minutes, and a dissolution profile of component (b) of 25% or more after 30 minutes, and 45% or more after 60 minutes at pH 4.5, said pharmaceutical oral fixed dose combination being bioequivalent to a free dose combination of Aliskiren and Valsartan.
摘要:
A solid pharmaceutical composition comprising a poorly water soluble drug, a polymer which is solid at room temperature, and a disintegrant in an amount of less than 10% by weight, wherein the amounts by weight are based on the total weight of the composition.
摘要:
In a method for receiver-side clock recovery for digital signals having a constant bit rate following cell-structured, asynchronous transmission with pauses of different length between individual cells using the loading state of an FIFO memory into which the received digital signals are written, at the start of a transmission the digital signals are initially read with a received clock into the FIFO memory holding multiple cells of the received signals until the FIFO memory is half filled. The digital signals written into the FIFO memory are read out with a readout clock whose frequency is smaller than the frequency of the received clock. During the readout a signal for controlling the frequency of the readout clock is derived from the respective loading state of the FIFO memory.
摘要:
Ink jet printing materials comprise a support and an ink receiving layer containing a pigment, a hydrophilic binder comprising polyvinyl alcohol, vinylpyrrolidone homopolymer and/or vinylpyrrolidone copolymer, and a quaternary ammonium compound.