公开(公告)号：US10973639B2

公开(公告)日：2021-04-13

申请号：US15865909

申请日：2018-01-09

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Asher L. Metchik ,  Gregory Scott Tyler, II ,  Matthew T. Winston ,  Sergio Delgado ,  Lauren R. Freschauf ,  Eric R. Dixon ,  Alexander J. Siegel

IPC: A61F2/24

Abstract: A system for implanting a repair device onto a native valve of a natural heart to repair the native valve of a patient during a non-open-heart procedure. The system includes a base assembly, a pair of paddles, and a pair of gripping members. The base assembly includes a shaft and a coupler attached to the shaft such that the coupler can be moved along the shaft. The paddles are movable between an open position, a closed position and a bailout position. The paddles and the gripping members are configured to attach to the native valve of the patient. Movement of the coupler along the shaft causes the paddles to move between the open position, the closed position, and the bailout position. When the paddles are in the bailout position, a bailout angle between each paddle of the pair of paddles and the shaft is greater than or equal to 120 degrees.

公开(公告)号：US10959846B2

公开(公告)日：2021-03-30

申请号：US15973892

申请日：2018-05-08

Applicant: Edwards Lifesciences Corporation

Inventor： Devin H. Marr ,  Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor ,  Asher L. Metchik ,  Matthew T. Winston ,  Grant Matthew Stearns ,  Sam Sok ,  Tam Van Nguyen ,  Rhayoung Kwon ,  Victoria Cheng-Tan Wu ,  Amanda Kristine Anderson White

IPC: A61F2/24 ,  A61B17/122 ,  A61B17/128 ,  A61B17/00

Abstract: An implantable prosthetic device can include a spacer member, a plurality of anchors, and a plurality of clasps. The spacer member can be configured to be disposed between native leaflets of a heart. The anchors can be coupled to the spacer member and configured to secure the native leaflets against the spacer member. The clasps can be coupled to a respective anchor and configured to secure the native leaflets to the anchors. The clasps can be independently movable between an open configuration and a closed configuration.

公开(公告)号：US10925735B2

公开(公告)日：2021-02-23

申请号：US16195598

申请日：2018-11-19

Applicant: Edwards Lifesciences Corporation

Inventor： Asher L. Metchik ,  Gregory Scott Tyler, II ,  Matthew T. Winston ,  Sergio Delgado ,  Lauren R. Freschauf ,  Eric Robert Dixon ,  Alexander J. Siegel

IPC: A61F2/24

Abstract: A system for implanting a repair device onto a native valve of a natural heart to repairing the native valve of a patient during a non-open-heart procedure. The system includes a surgical delivery instrument, a valve repair device, and a gripper control mechanism. The surgical delivery instrument has at least one lumen. The valve repair device is configured to be delivered through the lumen of the surgical delivery instrument and to be attached to a native valve of a patient. The valve repair device has a pair of paddles, and first and second gripping members. The paddles are movable between an open position and a closed position. The paddles and the first and second gripping members are configured to attach to the native valve of the patient. The gripper control mechanisms each include a suture and a wire having a loop at a distal end. The suture extends from the surgical delivery instrument and through the loop of the wire. The suture is removably attached to the gripping member. The loop of the wire is configured to engage the gripping member to move the gripping member between one or more positions.

公开(公告)号：US10925732B2

公开(公告)日：2021-02-23

申请号：US16134553

申请日：2018-09-18

Applicant: Edwards Lifesciences Corporation

Inventor： Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor ,  Asher L. Metchik ,  Matthew T. Winston ,  Sam Sok

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/04 ,  A61B17/34 ,  A61L27/04

Abstract: An exemplary valve repair system for repairing a native valve of a patient during a non-open-heart procedure includes a delivery device and a valve repair device. The delivery device includes a catheter, an actuation shaft, and a coupler. The valve repair device is configured to be delivered through the catheter. The valve repair device is configured to attach to a native valve of a patient. The valve repair device includes a coaption element having a first end portion and a second end portion, a proximal collar attached to the first end portion of the coaption element, first and second paddles connected to the coaption element, and a distal collar connected to the first and second paddles. The coupler is releasably connected to the proximal collar. The actuation shaft extends through the coupler, the proximal collar, and the coaption element. The actuation shaft is releasably connected to the distal collar.

公开(公告)号：US10653862B2

公开(公告)日：2020-05-19

申请号：US15796436

申请日：2017-10-27

Applicant: Edwards Lifesciences Corporation

Inventor： Matthew T. Winston ,  Christopher J. Olson ,  Asher L. Metchik ,  Tri D. Tran ,  Alexander J. Siegel

IPC: A61M25/01 ,  A61F2/24 ,  A61M25/06 ,  A61M25/00

Abstract: A delivery apparatus includes a steerable shaft having a proximal portion, a distal portion, and a pull-wire conduit that extends through the proximal and distal portions. A pull wire extends through the conduit and has a distal portion that is fixed to the shaft. An adjustment mechanism is connected to the proximal end portion of the pull wire and configured to increase and decrease tension in the pull wire to adjust the curvature of the shaft. The distal portion of the shaft has a steerable portion including one or more layers. A compression-resistance portion is incorporated into a layer of the steerable portion, and extends angularly along a portion of a cross-section of the layer. The layer of the steerable portion into which the compression-resistance portion is incorporated has a first hardness, and the compression-resistance portion has a second hardness that is greater than the first hardness.

公开(公告)号：US10517726B2

公开(公告)日：2019-12-31

申请号：US15154578

申请日：2016-05-13

Applicant: Edwards Lifesciences Corporation

Inventor： Mark Chau ,  David M. Taylor ,  Alexander J. Siegel ,  Christopher J. Olson ,  Sergio Delgado ,  Alexander H. Cooper ,  Lauren R. Freschauf ,  Asher L. Metchik ,  Matthew T. Winston ,  Cristobal R. Hernandez ,  Emil Karapetian ,  Bao Khuu ,  Eric Dixon

IPC: A61F2/24

Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion, wherein the prosthetic device is movable between a compressed configuration, in which the spacer body portion is radially compressed and is axially spaced relative to the anchor portion, and an expanded configuration, in which the spacer body portion expands radially outwardly relative to the compressed configuration and overlaps at least a portion of the anchor portion.

公开(公告)号：US10507109B2

公开(公告)日：2019-12-17

申请号：US15865861

申请日：2018-01-09

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Asher L. Metchik ,  Gregory Scott Tyler, II ,  Matthew T. Winston ,  Sergio Delgado ,  Lauren R. Freschauf ,  Eric R. Dixon ,  Alexander J. Siegel

IPC: A61F2/24

Abstract: A system for implanting a repair device onto a native valve of a natural heart to repair the native valve of a patient during a non-open-heart procedure. The system includes a surgical delivery instrument, a valve repair device, and a gripper control mechanism. The surgical delivery instrument has at least one lumen. The valve repair device is configured to be delivered through the lumen of the surgical delivery instrument and to attach to a native valve of a patient. The valve repair device includes a pair of paddles, and a pair of gripping members. The paddles are movable between an open position and a closed position. The paddles and the gripping members are configured to attach to a native valve of the patient. The gripper control mechanism is configured to independently move the first and second gripping members.

公开(公告)号：US10357351B2

公开(公告)日：2019-07-23

申请号：US15364670

申请日：2016-11-30

Applicant: Edwards Lifesciences Corporation

Inventor： Alexander H. Cooper ,  Michael R. Bialas ,  David M. Taylor ,  Gregory Scott Tyler, II ,  Zachary R. Kowalski ,  Art Z. Kwan ,  Darshin S. Patel ,  Asher L. Metchik ,  Michael J. Popp ,  Amanda K. Anderson

IPC: A61F2/00 ,  A61F2/24 ,  A61F2/95

Abstract: In a particular embodiment, the present disclosure provides a prosthetic valve delivery assembly that includes a storage tube. A prosthetic valve having a frame is at least partially disposed within the storage tube. A nose cone is located distally to the valve. A removable tab is disposed between the distal end of the frame and the nose cone. The tab assists in maintaining the position of the nose cone relative to the distal end of the frame.

公开(公告)号：US20190209299A1

公开(公告)日：2019-07-11

申请号：US16269341

申请日：2019-02-06

Applicant: Edwards Lifesciences Corporation

Inventor： Asher L. Metchik ,  Gregory Scott Tyler, II ,  Matthew T. Winston ,  Sergio Delgado ,  Lauren R. Freschauf ,  Eric Robert Dixon ,  Alexander J. Siegel

IPC: A61F2/24

CPC classification number: A61F2/246 ,  A61B17/12122 ,  A61B17/29 ,  A61B2017/00783 ,  A61B2017/2902 ,  A61B2017/2908 ,  A61B2017/2926 ,  A61B2017/2939 ,  A61B2017/2943 ,  A61B2017/320064 ,  A61F2/2466 ,  A61F2002/2484 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2230/0013

Abstract: A system for implanting a repair device onto a native valve of a natural heart to repairing the native valve of a patient during a non-open-heart procedure. The system includes a surgical delivery instrument, a valve repair device, and a gripper control mechanism. The surgical delivery instrument has at least one lumen. The valve repair device is configured to be delivered through the lumen of the surgical delivery instrument and to be attached to a native valve of a patient. The valve repair device includes a pair of paddles, and at least four gripping members. The paddles are movable between an open position and a closed position, and the paddles and the at least four gripping members are configured to attach to the native valve of a patient. The gripper control mechanism is configured to independently move each of the at least four gripping members.

公开(公告)号：US20190209298A1

公开(公告)日：2019-07-11

申请号：US16265135

申请日：2019-02-01

Applicant: Edwards Lifesciences Corporation

Inventor： Asher L. Metchik ,  Gregory Scott Tyler, II ,  Matthew T. Winston ,  Sergio Delgado ,  Lauren R. Freschauf ,  Eric Robert Dixon ,  Alexander J. Siegel

IPC: A61F2/24

CPC classification number: A61F2/246 ,  A61F2/2466 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2230/0013

Abstract: A system for implanting a repair device onto a native valve of a natural heart to repair the native valve of a patient during a non-open-heart procedure. The system includes a pair of paddles and a pair of gripping members. The paddles are movable between an open position and a closed position. The paddles and the gripping members are configured to attach to the native valve of the patient. The paddles are biased to the closed position, latched to the gripping members in the closed position, maintained in the closed position by a threaded connection, or otherwise maintained in the closed position.