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公开(公告)号：US20240335287A1
公开(公告)日：2024-10-10
申请号：US18745063
申请日：2024-06-17
发明人： Mark Chau , Travis Zenyo Oba , Sam Shafigh , Jean-Pierre Michel Rabbah , David M. Taylor , Philippe Marchand , Madison Paige Kukura , Cristobal R. Hernandez , Nancy Hoang Khuu , Florian Georg Deuschl , Biswa P. Das , Andrew Charles May , Bhumica A. Amin
IPC分类号： A61F2/24
CPC分类号： A61F2/2463 , A61F2/2466 , A61F2220/0008 , A61F2230/0008
摘要： Systems and methods are disclosed for use with a valve of a heart. An implant (100) includes a wing (120); a flexible frame (124); and a pair of anchor receivers (150). A pair of shafts (660) are transluminally advanced through a catheter (40), while the shafts are each engaged with a respective anchor receiver (150), to deploy the implant out of the catheter such that the wing extends away from the anchor receivers and over a first leaflet of the valve and toward an opposing leaflet of the valve, with a contact face (122) of the wing facing the first leaflet. A pair of drivers (70) secure the implant using a pair of anchors (30) to anchor each anchor receiver to tissue at respective sites of the heart. Other implementations are also described.
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公开(公告)号：US11793642B2
公开(公告)日：2023-10-24
申请号：US16522600
申请日：2019-07-25
发明人： Mark Chau , David M. Taylor , Alexander J. Siegel , Christopher J. Olson , Sergio Delgado , Alexander H. Cooper , Lauren R. Freschauf , Asher L. Metchik , Matthew T. Winston , Cristobal R. Hernandez , Emil Karapetian , Bao Khuu , Eric Robert Dixon
IPC分类号： A61F2/24
CPC分类号： A61F2/246 , A61F2/2454 , A61F2/2463 , A61F2/2466 , A61F2220/0016 , A61F2310/00023
摘要： In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. The spacer body can be made from braided, self-expandable metallic thread. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.
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公开(公告)号：US20230190469A1
公开(公告)日：2023-06-22
申请号：US18172806
申请日：2023-02-22
发明人： Emil Karapetian , Maria Charles Vija Stanislaus , Gregory Bak-Boychuk , Christopher J. Olson , Cristobal R. Hernandez , William C. Brunnett , Netanel Benichou , Lauren R. Freschauf , Alexander J. Siegel , Stanton J. Rowe , Alison S. Curtis
CPC分类号： A61F2/246 , A61F2/2466 , A61F2/2409 , A61F2/88 , A61F2/07 , A61F2/2436 , A61F2/2454 , A61F2/2427 , A61F2/2418 , A61F2002/825
摘要： This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises a main body formed by formed by a plurality of inner members forming an inner clover and a plurality of outer members forming an outer clover. The support frame can include gaps located between inner members of the plurality of inner members and outer members of the plurality of outer members. The inner clover can be radially inside the outer clover, and the outer clover can have larger dimensions than the inner clover. The support frames herein can be radially expandable and collapsible.
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公开(公告)号：US10507106B2
公开(公告)日：2019-12-17
申请号：US15482555
申请日：2017-04-07
发明人： Emil Karapetian , Maria Charles Vija Stanislaus , Gregory Bak-Boychuk , Christopher J. Olson , Cristobal R. Hernandez , William C. Brunnett , Netanel Benichou , Lauren R. Freschauf , Alexander J. Siegel
摘要： This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises an annular main body formed by a plurality of angled struts, the main body including a plurality of peaks formed by the intersection of respective adjacent struts. The support frame further comprises one or more leaflet-engaging mechanisms configured to engage leaflets of the heart valve. The support frame can be radially expandable and collapsible.
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公开(公告)号：US12011353B2
公开(公告)日：2024-06-18
申请号：US16522605
申请日：2019-07-25
发明人： Mark Chau , David M. Taylor , Alexander J. Siegel , Christopher J. Olson , Sergio Delgado , Alexander H. Cooper , Lauren R. Freschauf , Asher L. Metchik , Matthew T. Winston , Cristobal R. Hernandez , Emil Karapetian , Bao Khuu , Eric Robert Dixon
IPC分类号： A61F2/24
CPC分类号： A61F2/246 , A61F2/2454 , A61F2/2463 , A61F2/2466 , A61F2220/0016 , A61F2310/00023
摘要： In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. The spacer body can be configured to extend radially outwardly as the spacer body extends away from the distal end toward the proximal end. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.
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公开(公告)号：US20240041602A1
公开(公告)日：2024-02-08
申请号：US18489666
申请日：2023-10-18
发明人： Mark Chau , David M. Taylor , Alexander J. Siegel , Christopher J. Olson , Sergio Delgado , Alexander H. Cooper , Lauren R. Freschauf , Asher L. Metchik , Matthew T. Winston , Cristobal R. Hernandez , Emil Karapetian , Bao Khuu , Eric Robert Dixon , Amanda French , Philip P. Corso, JR.
IPC分类号： A61F2/24
CPC分类号： A61F2/246 , A61F2/2466 , A61F2/2454 , A61F2/2463 , A61F2220/0016 , A61F2310/00023
摘要： In one example, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. A size of the spacer body is configured to be adjusted after the spacer body is placed between the native valve leaflets and the pair of anchors are placed against the ventricular surfaces of the native heart valve leaflets. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.
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公开(公告)号：US11589988B2
公开(公告)日：2023-02-28
申请号：US16735352
申请日：2020-01-06
发明人： Emil Karapetian , Maria Charles Vija Stanislaus , Gregory Bak-Boychuk , Christopher J. Olson , Cristobal R. Hernandez , William C. Brunnett , Netanel Benichou , Lauren R. Freschauf , Alexander J. Siegel , Stanton J. Rowe , Alison S. Curtis
摘要： This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises a main body formed by formed by a plurality of inner members forming an inner clover and a plurality of outer members forming an outer clover. The support frame can include gaps located between inner members of the plurality of inner members and outer members of the plurality of outer members. The inner clover can be radially inside the outer clover, and the outer clover can have larger dimensions than the inner clover. The support frames herein can be radially expandable and collapsible.
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公开(公告)号：US20220273279A1
公开(公告)日：2022-09-01
申请号：US17744127
申请日：2022-05-13
发明人： Michael G. Valdez , Cristobal R. Hernandez , Eric Jason Noda , Hien T. Nguyen , Trizzie Trang Dang , Lilian Grace Myers , Linda Thai , Daniel James Murray , Don Huy Tran
摘要： A medical implant delivery system can comprise a puncture needle, a medical implant delivery catheter and the puncture needle being configured to be slidably advanced through a puncture needle lumen of the medical implant delivery catheter, a medical implant device positioned on the medical implant delivery catheter, and an outer delivery catheter comprising a medical implant delivery lumen, the medical implant delivery catheter being configured to slidably extend through the medical implant delivery lumen. A medical implant delivery system can comprise a puncture needle, a medical implant delivery catheter and the puncture needle being configured to slidably extend through the puncture needle lumen of the medical implant delivery catheter, a medical implant device positioned on the medical implant delivery catheter, an elongate housing adjacent to the medical implant delivery catheter, and an outer sheath around a portion of the medical implant delivery catheter and the elongate housing.
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公开(公告)号：US20230293176A1
公开(公告)日：2023-09-21
申请号：US18323350
申请日：2023-05-24
IPC分类号： A61B17/08 , A61B17/122 , A61F2/24 , A61B17/128 , A61B17/10
CPC分类号： A61B17/083 , A61B17/1227 , A61F2/2463 , A61B17/1285 , A61B17/10 , A61B2017/00349
摘要： Valve repair systems and clips attachable to one or more leaflets of a heart valve. The systems and clips can have center member, first and second clipping arms, and a tubular member. The first and second clipping arms are movable between an open position and a closed position. The clipping arms including respective first end portions coupled together and respective second end portions extendable axially and radially outward. The tubular member is disposed about the first end portion of the center member and first end portions of the first and second clipping arms. Axial motion of the tubular member relative to the center member or axial motion of the center member relative to the tubular member causes corresponding movement of the clipping arms between the open and closed positions. Other implementations are also disclosed.
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公开(公告)号：US11337810B2
公开(公告)日：2022-05-24
申请号：US16181858
申请日：2018-11-06
发明人： Emil Karapetian , Maria Charles Vija Stanislaus , Gregory Bak-Boychuk , Christopher J. Olson , Cristobal R. Hernandez , William C. Brunnett , Netanel Benichou , Lauren R. Freschauf , Alexander J. Siegel , Stanton J. Rowe , Alison S. Curtis
摘要： This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises a main body formed by formed by a plurality of inner members forming an inner clover and a plurality of outer members forming an outer clover. The support frame can include gaps located between inner members of the plurality of inner members and outer members of the plurality of outer members. The inner clover can be radially inside the outer clover, and the outer clover can have larger dimensions than the inner clover. The support frames herein can be radially expandable and collapsible.
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