公开(公告)号：US11571299B2

公开(公告)日：2023-02-07

申请号：US16921901

申请日：2020-07-06

Applicant: Edwards Lifesciences Corporation

Inventor： Hengchu Cao ,  Brian S. Conklin ,  Paul A. Schmidt ,  Grace Myong Kim ,  James A. Davidson ,  Hoa Trinh Tran ,  Kristy Luong Tam

IPC: A61F2/24

Abstract: Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions.

公开(公告)号：US20220183825A1

公开(公告)日：2022-06-16

申请号：US17653837

申请日：2022-03-07

Applicant: Edwards Lifesciences Corporation

Inventor： Hengchu Cao ,  Wei Sun

IPC: A61F2/24 ,  A61L27/36

Abstract: A low pressure gradient prosthetic heart valve for implant in a human. The valve includes a support frame with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. The commissure posts angle outward in a neutral state to widen the outflow orifice area. Also, the leaflets are designed to fit within the support frame and expand outward in a valve open state without creating a shelf or belly that would restrict flow.

公开(公告)号：US10940005B2

公开(公告)日：2021-03-09

申请号：US15953220

申请日：2018-04-13

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Sergio Delgado

IPC: A61F2/24 ,  A61B17/128 ,  A61B17/122 ,  A61B17/00 ,  A61B17/064 ,  A61F2/00

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. Each clasp has a fixed arm attached to the inner portion of the paddle and a moveable arm having a barbed portion. A hinge portion connects the fixed arm to the moveable arm. A cover wraps around at least a portion of the moveable arm of the clasp. At least one actuation suture is attached to the cover.

公开(公告)号：US10898327B2

公开(公告)日：2021-01-26

申请号：US15953283

申请日：2018-04-13

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Sergio Delgado

IPC: A61F2/24 ,  A61B17/128 ,  A61B17/122 ,  A61B17/00 ,  A61B17/064 ,  A61F2/00

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles have an outer portion and an inner portion. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the plurality of paddles. The clasps have a concave upper surface and a convex lower surface. The clasps include a fixed arm attached to the inner portion of the paddle, a moveable arm having a barbed portion, and a hinge portion connecting the fixed arm to the moveable arm.

公开(公告)号：US20200060812A1

公开(公告)日：2020-02-27

申请号：US16672381

申请日：2019-11-01

Applicant: Edwards Lifesciences Corporation

Inventor： Hengchu Cao ,  Wei Sun

IPC: A61F2/24 ,  A61L27/36

Abstract: A low pressure gradient prosthetic heart valve for implant in a human. The valve includes a support frame with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. The commissure posts angle outward in a neutral state to widen the outflow orifice area. Also, the leaflets are designed to fit within the support frame and expand outward in a valve open state without creating a shelf or belly that would restrict flow.

公开(公告)号：US10470759B2

公开(公告)日：2019-11-12

申请号：US15064006

申请日：2016-03-08

Applicant: Edwards Lifesciences Corporation

Inventor： Manouchehr A. Miraki ,  Hengchu Cao ,  Ralph Schneider

IPC: A61B17/04

Abstract: Some disclosed suture securement devices comprise a flat, thin, generally planar body that has one or more suture engagement slots extending into the body from a perimeter inlet for receiving sutures laterally into the device. The slots can be resiliently widened to receive a suture and then released to clamp onto the suture. Some embodiments include two or more such suture engagement slots that independently receive and secure different sutures. Some embodiments include one or more locking tabs that have a closed position that retains the slots against widening and blocks the inlet to the slot. In some embodiment two or more slots are position next to each other on the same side of the device, while in other embodiments slots are positioned on opposite sides of the device. Other types of suture securement devices are also disclosed.

公开(公告)号：US20180296329A1

公开(公告)日：2018-10-18

申请号：US15914143

申请日：2018-03-07

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Sergio Delgado ,  Lauren R. Freschauf

IPC: A61F2/24

Abstract: An implantable prosthetic has a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp has a fixed arm attached to the paddle. The clasps also have a moveable arm having a barbed portion and an end that is rounded. A hinge portion connects the fixed arm to the moveable arm.

公开(公告)号：US20240285396A1

公开(公告)日：2024-08-29

申请号：US18655672

申请日：2024-05-06

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Evan T. Schwartz ,  Tram Ngoc Nguyen ,  Jocelyn Chau ,  Hengchu Cao ,  Sandip Vasant Pawar

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2210/0009 ,  A61F2210/0014 ,  A61F2210/0057 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0091 ,  A61F2250/0017 ,  A61F2250/0098

Abstract: Certain examples of the disclosure concern a guard member for a docking device configured to receive a prosthetic valve. The guard member can include an expandable member and an elastic member extending along an axial length of the expandable member. The expandable member can be movable between a radially compressed state and a radially expanded state. When the expandable member is in the radially compressed state, the elastic member can be in an axially stretched state. The elastic member in the axially stretched state can be configured to return to a resting state, thereby moving the expandable member from the radially compressed state to the radially expanded state.

公开(公告)号：US11234822B2

公开(公告)日：2022-02-01

申请号：US16593373

申请日：2019-10-04

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Sergio Delgado ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick

IPC: A61F2/24 ,  A61B17/128 ,  A61B17/122 ,  A61B17/00 ,  A61B17/064 ,  A61F2/00

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are moveable from a closed position to an open position. The clasps are also moveable from an open position to a closed position. The implantable prosthetic device can be used to repair a native valve, such as a native mitral valve. Other embodiments are also described.

公开(公告)号：US10667912B2

公开(公告)日：2020-06-02

申请号：US15946604

申请日：2018-04-05

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Sergio Delgado ,  Lauren R. Freschauf

IPC: A61F2/24 ,  A61B17/128 ,  A61B17/122 ,  A61B17/00 ,  A61B17/064 ,  A61F2/00

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. Each clasp has a fixed arm attached to the paddle and a moveable arm having a barbed portion. A hinge portion connects the fixed arm to the moveable arm. The device does not include catch points when the paddles are in the open position and the clasps are in a closed condition.