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    SURGICAL CONDUIT LEAK TESTING
    14.
    发明申请
    SURGICAL CONDUIT LEAK TESTING 审中-公开
    手术泄漏测试

    公开(公告)号：US20160266004A1

    公开(公告)日：2016-09-15

    申请号：US15065720

    申请日：2016-03-09

    Applicant: Edwards Lifesciences Corporation

    Inventor： Mark Van Nest ,  Alyssa E. Kornswiet ,  Jackie P. Lau

    IPC: G01M3/28

    CPC classification number: G01M3/2876 ,  G01M3/2846

    Abstract: Systems, devices, and methods for leak testing surgical conduit grafts or valved conduits such as aortic-valved conduits with a pressurized gas such as air. Air is non-destructive and especially useful for leak testing conduits that have coatings or sealants that may be functionally impacted when exposed to fluids such as water or saline. Open ends of the conduit are clamped and sealed, and a pressurized gas introduced into an inner lumen thereof. A change in mass flow rate is measured to quantify the leakage. One end of a tubular conduit may be clamped to a fixed manifold, and the opposite end to a manifold slidably mounted to accommodate any conduit elongation when pressurized. The clamping and sealing structure may be pneumatic and/or mechanical, and complementary contoured clamp members may be used to seal a scalloped external sealing ring of an aortic conduit.

    Abstract translation: 用于泄漏测试的手术导管移植物或有管道的系统，装置和方法，例如具有加压气体如空气的主动脉瓣管道。 空气是非破坏性的，特别适用于具有涂层或密封剂的泄漏测试管道，当被暴露于诸如水或盐水的流体时可能会受到功能影响。 导管的开口端被夹紧和密封，并且将加压气体引入其内腔。 测量质量流量的变化以量化泄漏。 管状导管的一端可以被夹紧到固定歧管，并且可滑动地安装的歧管的相对端，以在加压时适应任何管道伸长。 夹紧和密封结构可以是气动和/或机械的，并且可以使用互补的轮廓夹紧构件来密封主动脉导管的扇形外部密封环。

    TISSUE-BASED REINFORCED HEART VALVES
    16.
    发明公开
    TISSUE-BASED REINFORCED HEART VALVES 审中-公开

    公开(公告)号：US20230248512A1

    公开(公告)日：2023-08-10

    申请号：US18301176

    申请日：2023-04-14

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： Tara J. Tod ,  Mark Van Nest ,  Kiem Bao Nguyen ,  Liqiong Gui ,  Lien Huong Thi Hoang ,  Son V. Nguyen ,  Hao Shang

    IPC: A61F2/24

    CPC classification number: A61F2/2412 ,  A61F2250/0098

    Abstract: Devices and methods for reinforcing a tissue-based heart valve are provided. A reinforced tissue valve can provide structure and rigidity to withstand stresses that occur within the vasculature. In some instances, thickened tissue provides structure or rigidity. In some instances, a biocompatible filler is utilized within folded, rolled, or layered tissue. In some instances, a mesh is included with a reinforced tissue valve for further strength. In some instances, a mesh frame is utilized along the sidewall of a tissue-based heart valve. In some instances, a leaflet assembly is provided within a conduit having thickened tissue at the leaflet commissures.

    VALVED AORTIC CONDUITS
    18.
    发明申请
    VALVED AORTIC CONDUITS 审中-公开

    公开(公告)号：US20190046317A1

    公开(公告)日：2019-02-14

    申请号：US16052775

    申请日：2018-08-02

    Applicant: Edwards Lifesciences Corporation

    Inventor： Michael C. Murad ,  Hilda Z. Fann ,  Mark Van Nest ,  John X. Wang ,  Derrick Johnson

    IPC: A61F2/24

    Abstract: A valved conduit including a bioprosthetic aortic heart valve connected to a tubular conduit graft forming an ascending aorta. The conduit graft may attach to the heart valve in a manner that facilitates a redo operation in which the valve is replaced with another valve. A sewing ring may be pre-attached to the inflow end of the graft, and then the valve connected to a delivery holder advanced into the graft and secured to the sewing ring. Dry bioprosthetic valves coupled with conduit grafts sealed with a bioresorbable medium can be stored with the delivery holder.

    Surgical conduit leak testing
    19.
    发明授权
    Surgical conduit leak testing 有权

    公开(公告)号：US10119882B2

    公开(公告)日：2018-11-06

    申请号：US15065720

    申请日：2016-03-09

    Applicant: Edwards Lifesciences Corporation

    Inventor： Mark Van Nest ,  Alyssa E. Kornswiet ,  Jackie P. Lau

    IPC: G01M3/28

    Abstract: Systems, devices, and methods for leak testing surgical conduit grafts or valved conduits such as aortic-valved conduits with a pressurized gas such as air. Air is non-destructive and especially useful for leak testing conduits that have coatings or sealants that may be functionally impacted when exposed to fluids such as water or saline. Open ends of the conduit are clamped and sealed, and a pressurized gas introduced into an inner lumen thereof. A change in mass flow rate is measured to quantify the leakage. One end of a tubular conduit may be clamped to a fixed manifold, and the opposite end to a manifold slidably mounted to accommodate any conduit elongation when pressurized. The clamping and sealing structure may be pneumatic and/or mechanical, and complementary contoured clamp members may be used to seal a scalloped external sealing ring of an aortic conduit.

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