公开(公告)号：US08109951B2

公开(公告)日：2012-02-07

申请号：US11093452

申请日：2005-03-30

申请人： Michael Maschke

发明人： Michael Maschke

IPC分类号： A61B17/22

CPC分类号： A61B17/320725 ,  A61B2017/22061 ,  A61B2090/3784

摘要： Device for implementing a cutting balloon intervention by means of a “cutting balloon” catheter, at the distal end of which is disposed an inflatable balloon with axially running blades mounted thereon, and which has IVUS monitoring, whereby the cutting balloon catheter is combined with an IVUS catheter to form an integrated module.

摘要翻译： 用于通过“切割气囊”导管实施切割气囊介入的装置，其在其远端设置有可安装在其上的轴向运行的叶片的可充气气囊，并且具有IVUS监测，由此将切割气囊导管与 IVUS导管形成一体化模块。

公开(公告)号：US20110280379A1

公开(公告)日：2011-11-17

申请号：US13105015

申请日：2011-05-11

申请人： Michael Maschke

发明人： Michael Maschke

IPC分类号： H05G1/02 ,  B82Y99/00

CPC分类号： A61B6/4435 ,  A61B6/4411 ,  A61B6/4441 ,  A61B6/4458 ,  A61B6/4464

摘要： An imaging apparatus comprising a ring-shaped gantry is provided. The gantry has a rotor arrangement rotating therein and a radiation source as well as at least one radiation detector. The gantry has at least one gantry segment which can be detached from the ring shape to allow the gantry to be opened laterally. The gantry is arranged on a supporting structure so as to be movable in space. The supporting structure is a floor, wall or ceiling mounted articulated-arm robot having at least four, preferably six, degrees of freedom of movement. The gantry has at least two radiation sources disposed offset by an angle on the rotor arrangement and associated with each of which is at least one radiation detector.

摘要翻译： 提供了一种包括环形台架的成像设备。 台架具有在其中旋转的转子布置和辐射源以及至少一个辐射检测器。 台架具有至少一个可从环形分离的龙门架部分，以便台架横向打开。 台架布置在支撑结构上，以便在空间中可移动。 支撑结构是具有至少四个，优选六个自由度的地板，墙壁或天花板安装的铰接臂机器人。 台架具有至少两个在转子装置上偏移角度的辐射源，并且每个辐射源与至少一个辐射探测器相关联。

公开(公告)号：US20110218380A1

公开(公告)日：2011-09-08

申请号：US13036065

申请日：2011-02-28

申请人： Michael Maschke

发明人： Michael Maschke

IPC分类号： A61M37/00 ,  A61K49/04 ,  A61P9/00 ,  B82Y5/00

CPC分类号： B82Y5/00 ,  A61K9/0009 ,  A61K9/5094 ,  A61K9/5115 ,  A61K9/5138 ,  A61K9/5146 ,  A61K49/0409 ,  A61K2035/124 ,  A61M5/007 ,  C12N11/00 ,  C12N11/14

摘要： For particularly effective stem cell therapy a nanoparticle is provided. The nanoparticle has a first element consisting of a magnetic material, a support or envelope element consisting of a biodegradable material, a first substance containing an x-ray contrast agent, and a second substance containing stem cells. The stem cells are embodied such that they can be used for angiogenesis or for myogenesis.

摘要翻译： 对于特别有效的干细胞治疗，提供了纳米颗粒。 纳米颗粒具有由磁性材料构成的第一元件，由可生物降解材料构成的支撑体或包络元件，含有X射线造影剂的第一物质和含有干细胞的第二物质。 干细胞被体现为使得它们可用于血管发生或用于肌发生。

公开(公告)号：US20110196395A1

公开(公告)日：2011-08-11

申请号：US13021928

申请日：2011-02-07

申请人： Michael Maschke

发明人： Michael Maschke

IPC分类号： A61B17/22

CPC分类号： A61B17/320758 ,  A61B5/0084 ,  A61B5/02007 ,  A61B5/055 ,  A61B5/061 ,  A61B8/0858 ,  A61B8/12 ,  A61B2090/3782 ,  A61M2025/09175

摘要： A guide wire featuring a tip is introduced into a vessel. An expander tool featuring a tip is introduced by pushing it over the guide wire into the vessel. For the expander tool introduced into the vessel at least one image is output to the operator of the expander tool via a viewing device. The image is a representation of the area of the inside of the vessel which, seen in a local direction of advance of the expander tool, lies directly in front of the tip of the expander tool. The image is determined on the basis of at least one image dataset which was acquired by at least one sensor. The at least one sensor is arranged at the tip of the guide wire or on the expander tool behind its tip.

摘要翻译： 将特征为尖端的引导线引入到容器中。 通过将引导线推到容器中，引入具有尖端的膨胀器工具。 对于引入到容器中的扩张器工具，至少一个图像经由观察装置输出到膨胀器工具的操作者。 该图像是在膨胀器工具的局部方向上看到的容器内部的区域的表示，其直接位于膨胀器工具的尖端的前方。 基于由至少一个传感器获取的至少一个图像数据集来确定图像。 所述至少一个传感器布置在所述导丝的尖端处或在所述扩展器工具的尖端之后。

公开(公告)号：US07993361B2

公开(公告)日：2011-08-09

申请号：US11093451

申请日：2005-03-30

申请人： Michael Maschke

发明人： Michael Maschke

IPC分类号： A61M29/00

CPC分类号： A61B17/3207 ,  A61B90/37

摘要： Device for removing a total vascular occlusion with the aid of a CTO catheter with expansion tongs arranged at the front end and OCT monitoring, the CTO catheter being combined with an OCT catheter to form an integrated unit.

摘要翻译： 借助于具有布置在前端的扩张钳的CTO导管和OCT监测来去除总血管闭塞的装置，CTO导管与OCT导管组合以形成一体的单元。

公开(公告)号：US20100332254A1

公开(公告)日：2010-12-30

申请号：US12492329

申请日：2009-06-26

申请人： Michael Maschke ,  Sebastian Schmidt ,  Gudrun Zahlmann

发明人： Michael Maschke ,  Sebastian Schmidt ,  Gudrun Zahlmann

IPC分类号： G06Q50/00 ,  A61B5/00 ,  G06N5/02 ,  A61B6/00

CPC分类号： A61B6/481 ,  A61B5/201 ,  A61B5/411 ,  A61B5/7275 ,  G06Q50/24

摘要： A system and method of diagnosing kidney syndromes using an intravenous pyelogram (IVP) is described. The system includes an X-ray imaging device and an in-vitro diagnostic (IVD) device. The IVD device is used to identify risk factors such as sensitivity to contrast agents, or to indicate or rule out other syndromes which may have symptoms similar to kidney malfunction. The level of blood components such as creatinine may be used, in conjunction with other medical data and IVD tests, to determine a risk score for the patient. The risk score may be used to recommend modifications to a baseline procedure such as change in the volume or type of contrast agent, the number of X-rays, or the performance of post-procedure dialysis.

摘要翻译： 描述了使用静脉肾盂造影（IVP）诊断肾综合征的系统和方法。 该系统包括X射线成像装置和体外诊断（IVD）装置。 IVD装置用于识别对造影剂的敏感性等危险因素，或指示或排除可能具有类似于肾功能障碍的症状的其他综合征。 可以结合其他医疗数据和IVD测试来使用血液成分如肌酐的水平来确定患者的风险评分。 风险评分可用于推荐对基线程序的修改，例如造影剂的体积或类型的变化，X射线的数量或手术后透析的表现。

公开(公告)号：US20100241147A1

公开(公告)日：2010-09-23

申请号：US12719880

申请日：2010-03-09

申请人： Michael Maschke

发明人： Michael Maschke

IPC分类号： A61B17/22

CPC分类号： A61B17/320016 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/02007 ,  A61B5/411 ,  A61B5/6852 ,  A61B5/7207 ,  A61B8/06 ,  A61B8/12 ,  A61B17/3207 ,  A61B17/320783 ,  A61M25/0147 ,  A61M25/0158 ,  A61M2025/0166 ,  G01R33/285

摘要： A catheter for removing plaque in a blood vessel and a medical apparatus comprising a catheter of this kind are proposed. The catheter has a catheter sheath, a cutter for removing plaque disposed in the region of the distal end of the catheter sheath, a catheter tip disposed in the region of the distal end of the catheter sheath and bendable relative to the catheter sheath, and at least one imaging sensor arranged in the region of the distal end of the catheter sheath or in the bendable catheter tip. The image signals recorded by means of the catheter are transmitted for display purposes to an image processing and playback device. A method for assisting a minimally invasive intervention to remove plaque in a blood vessel by the catheter is also provided.

摘要翻译： 提出了用于去除血管中斑块的导管和包括这种导管的医疗装置。 导管具有导管护套，用于去除设置在导管护套的远端的区域中的斑块的切割器，设置在导管护套的远端的区域中并相对于导管护套弯曲的导管末端，并且在 至少一个成像传感器布置在导管护套的远端或可弯曲的导管尖端的区域中。 通过导管记录的图像信号被传输以用于显示目的到图像处理和回放装置。 还提供了一种用于辅助微创干预以通过导管去除血管中的斑块的方法。

公开(公告)号：US20100228101A1

公开(公告)日：2010-09-09

申请号：US12397856

申请日：2009-03-04

申请人： Michael Maschke ,  Sebastian Schmidt

发明人： Michael Maschke ,  Sebastian Schmidt

IPC分类号： A61B5/00 ,  A61M37/00

CPC分类号： A61B6/504 ,  A61B5/0022 ,  A61B5/031 ,  A61B5/055 ,  A61B6/03 ,  G06F19/321 ,  G06F19/3418 ,  G06F19/3481 ,  G16H10/40

摘要： A method and apparatus for diagnosing and treating stroke is described. A preliminary diagnosis of a stroke and the type of stroke is made based on a patient anamnesis and an in-vitro diagnostic device (IVD), configured to analyze biomarkers in a patient blood sample. In one example, the diagnosis is confirmed using a C-arm X-ray device and, if a hemorrhagic stroke is confirmed, interventional therapy may be performed using the C-arm X-ray device to guide a catheter or other interventional device. Where an ischemic stroke is confirmed, the appropriate thrombolytic therapy may be administered. The IVD device may be located in an emergency vehicle, and the test may be results transmitted to the medical facility while the patient is in transit.

摘要翻译： 描述了用于诊断和治疗中风的方法和装置。 基于患者体检和体外诊断装置（IVD）进行中风的初步诊断和中风类型，其被配置为分析患者血液样品中的生物标志物。 在一个示例中，使用C臂X射线装置确认诊断，并且如果确认出血性中风，则可以使用C臂X射线装置进行介入治疗以引导导管或其他介入装置。 在确认缺血性中风的情况下，可以施用适当的溶栓治疗。 IVD装置可以位于紧急车辆中，并且该测试可以在患者在运送期间将结果传送到医疗设施。

公开(公告)号：US20100174555A1

公开(公告)日：2010-07-08

申请号：US12318648

申请日：2009-01-05

申请人： Klaus Abraham-Fuchs ,  Karsten Hiltawsky ,  Michael Maschke ,  Sebastian Schmidt ,  Gudrun Zahlmann

发明人： Klaus Abraham-Fuchs ,  Karsten Hiltawsky ,  Michael Maschke ,  Sebastian Schmidt ,  Gudrun Zahlmann

IPC分类号： G06Q50/00 ,  G06N5/02 ,  G06F17/30

CPC分类号： G06Q50/22 ,  G06F19/328 ,  G06F19/3481 ,  G06Q10/04 ,  G06Q10/10 ,  G06Q50/24 ,  G16H50/20

摘要： At least one embodiment of the present invention refers to a method, a system, a computer readable medium and/or a computer program product for optimizing a clinical pathway. The clinical pathway includes a sequence of actions. In at least one embodiment, he method aims at finding the best suitable and optimal following action for a respective action. There is provided a set of rules, patient information data and optimization criteria. After having received a symptom or an action there is deduced a set of possible following actions. After having deduced all possible following actions, these possible following actions are evaluated by the optimization criteria. After evaluation the optimal following action is suggested as a result.

摘要翻译： 本发明的至少一个实施例涉及用于优化临床途径的方法，系统，计算机可读介质和/或计算机程序产品。 临床路径包括一系列动作。 在至少一个实施例中，他的方法旨在找到针对相应动作的最佳适合和最优跟随动作。 提供了一组规则，患者信息数据和优化标准。 在收到症状或行动后，推断出一组可能的以下行动。 在推导了所有可能的以下操作之后，这些可能的以下操作将通过优化标准进行评估。 评估结果后，建议采用最佳的追踪措施。

公开(公告)号：US07748900B2

公开(公告)日：2010-07-06

申请号：US11827015

申请日：2007-07-10

申请人： Michael Maschke

发明人： Michael Maschke

IPC分类号： H05G1/02

CPC分类号： B25J11/00 ,  A61B6/102 ,  A61B6/4405 ,  A61B6/4441 ,  A61B6/4458 ,  A61B6/547 ,  A61B6/548 ,  B25J5/00 ,  G05B2219/37569 ,  G05B2219/40252 ,  G05B2219/45169

摘要： There is described an x-ray system with an x-ray source, an x-ray detector and at least one industrial robot having at least three, in particular six, axes of rotation, in which the x-ray source and/or the x-ray detector are/is arranged, directly or by means of a bearer, on the industrial robot, and where the industrial robot is constructed to be mobile, in particular is arranged on a device trolley.

摘要翻译： 描述了具有x射线源，x射线检测器和至少一个具有至少三个，特别是六个旋转轴线的工业机器人的x射线系统，其中x射线源和/或 X射线检测器直接地或者通过承载件被布置在工业机器人上，并且工业机器人被构造为可移动的，特别地布置在设备手推车上。