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公开(公告)号:US5550050A
公开(公告)日:1996-08-27
申请号:US228403
申请日:1994-04-15
IPC分类号: A61K9/48 , A61K9/00 , A61K9/64 , A61K35/12 , A61K35/23 , A61K38/00 , A61K45/00 , A61K48/00 , A61P27/02 , C07K14/475 , C07K14/48 , C12N5/00 , C12N5/071 , C12N1/36 , C12N1/38
CPC分类号: A61K9/0024 , A61K35/13 , A61K35/22 , A61K9/0048 , A61K9/0085 , C07K14/475 , C07K14/48 , C12N5/0614 , C12N5/0618 , A61K38/00 , A61K48/00 , A61K9/0092 , C12N2500/02 , C12N2500/34
摘要: This invention provides methods for implanting encapsulated cells in a host comprising exposing cells to restrictive conditions for a sufficient period of time to establish a desired cell property in response to the restrictive conditions and implanting the encapsulated cells in a host, the cell property being substantially maintained following implantation. Also provided are cells produced by exposure to restrictive conditions.
摘要翻译: 本发明提供了用于将包封的细胞植入宿主中的方法,其包括将细胞暴露于限制性条件足够长的时间以响应限制性条件建立所需的细胞特性并将包封的细胞植入宿主中,细胞特性基本保持 植入后。 还提供了通过暴露于限制条件产生的细胞。