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公开(公告)号：US09873748B2
公开(公告)日：2018-01-23
申请号：US14582100
申请日：2014-12-23
Applicant: GENENTECH, INC.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
CPC classification number: C07K16/40 , A61K2039/505 , C07K14/71 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/75 , C07K2317/92
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号：US09738727B2
公开(公告)日：2017-08-22
申请号：US13651289
申请日：2012-10-12
Applicant: Genentech, Inc.
Inventor： Yan Wu , Menno van Lookeren-Campagne , Daniel Kirchhofer , Michael Terry Lipari , Kenneth J. Katschke, Jr. , Paul M. Moran , Scott Stawicki , Wei-Ching Liang
IPC: C07K16/40
CPC classification number: C07K16/40 , C07K2317/34 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-HtrA1 antibodies and methods of using the same.
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公开(公告)号：US09512217B2
公开(公告)日：2016-12-06
申请号：US14148414
申请日：2014-01-06
Applicant: Genentech, Inc.
Inventor： Yongmei Chen , Yan (Helen) Hu , Wenjun Ouyang , Scott Stawicki , Yan Wu
IPC: A61K39/395 , C07K16/24
CPC classification number: C07K16/244 , C07K2317/31 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
Abstract: The present invention relates generally to antibodies cross-reactive with IL-17A and IL-17F, and bispecific anti-IL-17A/F and their uses.
Abstract translation: 本发明一般涉及与IL-17A和IL-17F交叉反应的抗体，以及双特异性抗IL-17A / F及其用途。
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公开(公告)号：US20160319038A1
公开(公告)日：2016-11-03
申请号：US15214160
申请日：2016-07-19
Applicant: GENENTECH, INC.
Inventor： YONGMEI CHEN , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
CPC classification number: C07K16/40 , A61K2039/505 , C07K14/71 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/75 , C07K2317/92
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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