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公开(公告)号：US20170058049A1
公开(公告)日：2017-03-02
申请号：US15234649
申请日：2016-08-11
Applicant: Genentech, Inc.
Inventor： Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
CPC classification number: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
Abstract: The invention provides antibodies to specific neural proteins and methods of using the same.
Abstract translation: 本发明提供了针对特定神经蛋白的抗体及其使用方法。
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公开(公告)号：US10882921B2
公开(公告)日：2021-01-05
申请号：US16284774
申请日：2019-02-25
Applicant: GENENTECH, INC.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号：US20180105605A1
公开(公告)日：2018-04-19
申请号：US15837801
申请日：2017-12-11
Applicant: Genentech, Inc.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
CPC classification number: C07K16/40 , A61K2039/505 , C07K14/71 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/75 , C07K2317/92
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号：US09453079B2
公开(公告)日：2016-09-27
申请号：US14292461
申请日：2014-05-30
Applicant: Genentech, Inc.
Inventor： Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
IPC: C07K16/18 , A61K39/395 , C07K16/40 , A61K47/48 , G01N33/573 , A61K39/00
CPC classification number: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
Abstract: The invention provides antibodies to specific neural proteins and methods of using the same.
Abstract translation: 本发明提供了针对特定神经蛋白的抗体及其使用方法。
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公开(公告)号：US20150218276A1
公开(公告)日：2015-08-06
申请号：US14582100
申请日：2014-12-23
Applicant: GENENTECH, INC.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
IPC: C07K16/28
CPC classification number: C07K16/40 , A61K2039/505 , C07K14/71 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/75 , C07K2317/92
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
Abstract translation: 目前公开的主题提供了结合KLB和FGFR1的抗体及其使用方法。 在某些实施方案中，本公开的抗体包括结合存在于FGFR1上并与KLB上存在的表位结合的双特异性抗体。
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Patent Agency Ranking
公开(公告)号：US20180312579A1
公开(公告)日：2018-11-01
申请号：US15837647
申请日：2017-12-11
Applicant: Genentech, Inc,
Inventor： Elaine Storm , Frederic J. de Sauvage , Jeremy M. Murray , Cameron L. Noland , Yan Wu , Christine Tan , Jo-Anne Hongo , Yongmei Chen
CPC classification number: C07K16/18 , A61K39/3955 , A61K45/06 , A61K47/6843 , A61K2039/505 , C07K16/2818 , C07K16/3046 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: Provided herein are anti-RSPO antibodies, in particular anti-RSPO2 antibodies and/or anti-RSPO3 antibodies, and methods of using the same.
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公开(公告)号：US20140314763A1
公开(公告)日：2014-10-23
申请号：US14148414
申请日：2014-01-06
Applicant: Genentech, Inc.
Inventor： Yongmei Chen , Yan (Helen) Hu , Wenjun Ouyang , Scott Stawicki , Yan Wu
IPC: C07K16/24
CPC classification number: C07K16/244 , C07K2317/31 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
Abstract: The present invention relates generally to antibodies cross-reactive with IL-17A and IL-17F, and bispecific anti-IL-17A/F and their uses.
Abstract translation: 本发明一般涉及与IL-17A和IL-17F交叉反应的抗体，以及双特异性抗IL-17A / F及其用途。
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公开(公告)号：US20140286963A1
公开(公告)日：2014-09-25
申请号：US14292461
申请日：2014-05-30
Applicant: Genentech, Inc.
Inventor： Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
IPC: C07K16/40 , G01N33/573 , A61K47/48
CPC classification number: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
Abstract: The invention provides antibodies to specific neural proteins and methods of using the same.
Abstract translation: 本发明提供了针对特定神经蛋白的抗体及其使用方法。
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公开(公告)号：US20240026033A1
公开(公告)日：2024-01-25
申请号：US18194276
申请日：2023-03-31
Applicant: Genentech, Inc.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
CPC classification number: C07K16/40 , C07K14/71 , C07K16/2863 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/75 , C07K2317/92 , C07K2317/40 , C07K2317/41 , C07K2317/524 , C07K2317/567 , C07K2317/71 , A61K2039/505
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号：US20220064331A1
公开(公告)日：2022-03-03
申请号：US17341990
申请日：2021-06-08
Applicant: GENENTECH, INC.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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