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    Injectable microspheres
    12.
    发明授权
    Injectable microspheres 有权
    可注射微球

    公开(公告)号：US08092835B1

    公开(公告)日：2012-01-10

    申请号：US13269738

    申请日：2011-10-10

    申请人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    发明人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    IPC分类号： A61K9/14

    CPC分类号： A61K9/0019 ,  A61K9/1647 ,  Y10T428/2982

    摘要： Injectable microspheres are obtained from double bond functionalized polyhydric alcohol ester by a method comprising dissolving the double bond functionalized esters in a hydrophobic organic solvent, forming an aqueous solution of stabilizer, forming an oil in water emulsion where the solution of stabilizer constitutes the continuous phase and the solution of ester constitutes the disperse phase and evaporating the organic solvent or from block copolymer of PGCLM and methoxy poly(ethylene glycol).

    摘要翻译： 可注射的微球体是通过将双键官能化的酯溶解在疏水性有机溶剂中，形成稳定剂的水溶液，形成稳定剂溶液形成连续相的水乳液的方法从双键官能化的多元醇酯得到的， 酯溶液构成分散相并蒸发有机溶剂或由PGCLM和甲氧基聚（乙二醇）的嵌段共聚物蒸发。

    Hydrogel forming system comprising peg derivative precursor
    13.
    发明申请
    Hydrogel forming system comprising peg derivative precursor 有权
    包含栓衍生物前体的水凝胶形成体系

    公开(公告)号：US20050202060A1

    公开(公告)日：2005-09-15

    申请号：US11060279

    申请日：2005-02-18

    申请人： Daqing Wu ,  Chih-Chang Chu

    发明人： Daqing Wu ,  Chih-Chang Chu

    IPC分类号： A61F2/00

    CPC分类号： A61L31/10 ,  A61L31/145 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/00

    摘要： Variation in precursor ratio and mass of double bond functionalized polyhydric alcohol precursor and polyethylene glycol diacrylate precursor provide a wide range of release rates of drug or other biologically active agent from hydrogel formed therefrom.

    摘要翻译： 双键官能化多元醇前体和聚乙二醇二丙烯酸酯前体的前体比和质量的变化提供药物或其它生物活性剂从其形成的水凝胶的宽范围的释放速率。

    Tobacco-free pouched product containing flavor beads providing immediate and long lasting flavor release
    14.
    发明授权
    Tobacco-free pouched product containing flavor beads providing immediate and long lasting flavor release 有权
    含有风味珠的含烟草的包装产品提供立即和持久的口味释放

    公开(公告)号：US08747562B2

    公开(公告)日：2014-06-10

    申请号：US12789125

    申请日：2010-05-27

    申请人： Munmaya K. Mishra ,  Biao Duan ,  Daqing Wu ,  William R. Sweeney

    发明人： Munmaya K. Mishra ,  Biao Duan ,  Daqing Wu ,  William R. Sweeney

    IPC分类号： A24B15/30

    CPC分类号： A24B15/16 ,  A23V2002/00 ,  A24B13/00 ,  A24B15/283 ,  A23V2200/224 ,  A23V2250/5072 ,  A23V2250/51084 ,  A23V2250/5026

    摘要： A tobacco-free oral pouch product providing immediate and long lasting flavor release comprises a pouch wrapper and tobacco-free flavor beads contained within the pouch wrapper. The flavor beads comprise at least one of microcrystalline cellulose, pectin and sodium alginate, at least one polymer having a higher solubility in saliva than microcrystalline cellulose, pectin and/or sodium alginate, and at least one flavorant. The pectin and sodium alginate are cross-linked. The tobacco-free flavor beads provide immediate release of the flavorant upon placement of a pouch product in a user's mouth and long lasting release of the flavorant for about 15 minutes to about 80 minutes. The oral pouch product contains only tobacco-free flavor beads.

    摘要翻译： 提供立即和持久的风味释放的无烟口服泡沫产品包括袋包装中包含的小袋包装物和无烟味的风味小珠。 风味珠粒包含微晶纤维素，果胶和海藻酸钠中的至少一种，至少一种在唾液中的溶解度高于微晶纤维素，果胶和/或藻酸钠的至少一种调味剂。 果胶和藻酸钠是交联的。 无烟味的香料颗粒在将小袋产品放置在使用者的口腔中并且持续释放食用香料约15分钟至约80分钟时，立即释放食用香料。 口袋产品只含有无烟味的香料珠。

    Silicone hydrogel lens with a grafted hydrophilic coating
    15.
    发明授权
    Silicone hydrogel lens with a grafted hydrophilic coating 有权
    硅胶水凝胶透镜带有接枝亲水涂层

    公开(公告)号：US08409599B2

    公开(公告)日：2013-04-02

    申请号：US12917504

    申请日：2010-11-02

    申请人： Daqing Wu ,  Xinming Qian ,  John Dallas Pruitt

    发明人： Daqing Wu ,  Xinming Qian ,  John Dallas Pruitt

    IPC分类号： A61C8/00

    CPC分类号： G02C7/04 ,  G02B1/043 ,  C08L101/14

    摘要： The invention provides a cost-effective method for applying a hydrophilic coating onto a silicone hydrogel contact lens based on Fenton chemistry. The hydrophilic coating is covalently attached onto the contact lens at room temperature without UV irradiation. The invention also provides silicone hydrogel contact lenses having a hydrophilic coating obtained according to the method of the invention.

    摘要翻译： 本发明提供了一种基于Fenton化学将亲水性涂层施加到硅酮水凝胶隐形眼镜上的成本有效的方法。 亲水涂层在室温下共价附着在隐形眼镜上，无紫外线照射。 本发明还提供了具有根据本发明方法获得的亲水涂层的硅酮水凝胶隐形眼镜。

    METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES
    17.
    发明申请
    METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES 有权
    制造紫外线吸收光学眼镜的方法

    公开(公告)号：US20120023869A1

    公开(公告)日：2012-02-02

    申请号：US13186616

    申请日：2011-07-20

    申请人： Newton T. Samuel ,  John Dallas Pruitt ,  Daqing Wu ,  Selma Kuyu

    发明人： Newton T. Samuel ,  John Dallas Pruitt ,  Daqing Wu ,  Selma Kuyu

    IPC分类号： G02C7/04 ,  B65B55/22 ,  B65B55/02 ,  C08G77/388 ,  C08G77/38

    CPC分类号： G02B1/043 ,  B29D11/00038 ,  B29D11/00048 ,  G02C7/04 ,  G02C7/049 ,  C08L101/14

    摘要： Described herein is a cost-effective and time-efficient method for making UV-absorbing contact lenses. In contrast to the conventional method for making UV-absorbing contact lenses which involves copolymerizing a lens forming composition including a UV-absorbing vinylic monomer, a method of the invention involves covalent attachment of a UV-absorbing compound having a second reactive functional group to a preformed contact lens having a first reactive functional group therein and/or thereon.

    摘要翻译： 本文描述了制造紫外线吸收隐形眼镜的成本效益和时间有效的方法。 与使紫外线吸收性隐形眼镜相关的常规方法与包含紫外线吸收性乙烯基单体的透镜形成组合物共聚，本发明的方法涉及将具有第二反应性官能团的紫外线吸收性化合物与 其中和/或其上具有第一反应性官能团的预成型隐形眼镜。

    Injectable Microspheres
    18.
    发明申请
    Injectable Microspheres 有权
    可注射微球

    公开(公告)号：US20110151004A1

    公开(公告)日：2011-06-23

    申请号：US13015193

    申请日：2011-01-27

    申请人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    发明人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    IPC分类号： A61K9/14 ,  B32B5/16 ,  C08G63/08

    CPC分类号： A61K9/0019 ,  A61K9/1647 ,  Y10T428/2982

    摘要： Injectable microspheres are obtained from double bond functionalized polyhydric alcohol ester by a method comprising dissolving the double bond functionalized esters in a hydrophobic organic solvent, forming an aqueous solution of stabilizer, forming an oil in water emulsion where the solution of stabilizer constitutes the continuous phase and the solution of ester constitutes the disperse phase and evaporating the organic solvent or from block copolymer of PGCLM and methoxy poly(ethylene glycol).

    摘要翻译： 可注射的微球体是通过将双键官能化的酯溶解在疏水性有机溶剂中，形成稳定剂的水溶液，形成稳定剂溶液形成连续相的水乳液的方法从双键官能化的多元醇酯得到的， 酯溶液构成分散相并蒸发有机溶剂或由PGCLM和甲氧基聚（乙二醇）的嵌段共聚物蒸发。

    Hydrogel forming system comprising PEG derivative precursor
    19.
    发明授权
    Hydrogel forming system comprising PEG derivative precursor 有权
    包含PEG衍生物前体的水凝胶形成体系

    公开(公告)号：US07670616B2

    公开(公告)日：2010-03-02

    申请号：US11060279

    申请日：2005-02-18

    申请人： Daqing Wu ,  Chih-Chang Chu

    发明人： Daqing Wu ,  Chih-Chang Chu

    IPC分类号： A61F2/02

    CPC分类号： A61L31/10 ,  A61L31/145 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/00

    摘要： Variation in precursor ratio and mass of double bond functionalized polyhydric alcohol precursor and polyethylene glycol diacrylate precursor provide a wide range of release rates of drug or other biologically active agent from hydrogel formed therefrom.

    摘要翻译： 双键官能化多元醇前体和聚乙二醇二丙烯酸酯前体的前体比和质量的变化提供药物或其它生物活性剂从其形成的水凝胶的宽范围的释放速率。