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公开(公告)号：US06585961B1
公开(公告)日：2003-07-01
申请号：US10016611
申请日：2001-11-30
申请人： Richard F. Stockel
发明人： Richard F. Stockel
IPC分类号： A61K716
CPC分类号： A61Q11/00 , A61K8/0291 , A61K8/33 , A61K8/34 , A61K8/347 , A61K8/37 , A61K8/39 , A61K8/44 , A61K8/442 , A61K8/463 , A61K8/4913 , A61K8/55 , A61K8/86 , A61K8/90 , A61K31/05 , A61K31/352 , A61K31/60 , A61K2800/413 , A61K2800/51 , B82Y5/00 , Y02A50/406 , A61K2300/00
摘要： Aqueous antimicrobial and biofilm removal compositions, comprising essential oils and certain cationic, anionic, amphoteric or non-ionic surfactants individually or in combination having an hydrophile-lipophile balance (HLB) of about 16 or above are effective oral mouthwashes and topical antimicrobial solutions. Optionally C2, C3, benzyl, 3-phenylpropanol or 2-phenylethanol alcohols can be added singularly or in combination from about 2 to about 20v/w %. Other optically ingredients include antimicrobial enhances and biofilm removal agents e.g., chelating compounds and certain organic acids.
摘要翻译： 包含精油和某些阳离子，阴离子，两性或非离子表面活性剂的水性抗微生物和生物膜去除组合物是单独或组合具有约16或更高亲水亲油平衡（HLB）的有效口服漱口剂和局部抗微生物溶液。 任选地，C2，C3，苄基，3-苯基丙醇或2-苯基乙醇醇可以单独或组合加入约2至约20v / w％。其它光学成分包括抗微生物增强剂和生物膜去除剂，例如螯合化合物和某些有机酸 。
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公开(公告)号：US4536571A
公开(公告)日：1985-08-20
申请号：US484874
申请日：1983-04-14
CPC分类号： C07F15/0093 , C07H23/00
摘要： The toxic effects of platinum compounds used in chemotherapy can be negated by the use of a selenium-containing compound. A new selenium-containing platinum compound has been found to be useful as a so-called platinum compound type anti-cancer medicine which can self-detoxify platinum toxicity.
摘要翻译： 化学治疗中使用的铂化合物的毒性作用可以通过使用含硒化合物来消除。 已经发现新的含硒铂化合物可用作能够自我解毒铂毒性的所谓的铂化合物型抗癌药物。
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公开(公告)号：US4469503A
公开(公告)日：1984-09-04
申请号：US481647
申请日：1983-04-04
申请人： Richard F. Stockel
发明人： Richard F. Stockel
摘要： The invention relates to a fertilizer composition which comprises coal ash, and a relatively water insoluble polymer capable of gradually decomposing to slowly release nitrogen polymerized uniformly on said coal ash. The polymer is formed by the in situ polymerization of an aldehyde and a polymerizable organic nitrogen containing compound capable of reacting with two or more equivalents of said aldehyde in the presence of an acid. The coal can be fly ash, bottom ash or boiler slag and can be derived from anthracite, bituminous or subbituminous coal or from lignite coal. The acid can be phosphoric acid, the aldehyde formaldehyde and the polymerizable organic nitrogen containing compound urea.
摘要翻译： 本发明涉及包含煤灰的肥料组合物和能够逐渐分解以缓慢释放在所述煤灰上均匀聚合的氮的相对不溶于水的聚合物。 聚合物通过在酸的存在下，能够与两种或更多当量的所述醛反应的醛和可聚合的含有机氮化合物的原位聚合而形成。 煤可以是飞灰，底灰或锅炉渣，可以来自无烟煤，烟煤或次烟煤或褐煤。 酸可以是磷酸，醛甲醛和可聚合的含有机氮的化合物脲。
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公开(公告)号：US20100056628A1
公开(公告)日：2010-03-04
申请号：US12589155
申请日：2009-10-19
IPC分类号： A01N37/12 , C07C229/02 , A01P15/00
CPC分类号： A01N25/30 , A23B4/10 , A23B4/20 , C07C229/26 , C07C279/14 , A01N37/46 , A01N43/38 , A01N43/50 , A01N47/44
摘要： Green and naturally derived biocides such as Nα—(C1-C22) alkanoyl di basic amino acid alkyl (C1 to C22) ester salt cationic molecules can be combined with an anionic molecule not generally considered as having significant biocidal activity to provide antimicrobial, antibacterial, and/or antifungal properties with multifunctional benefits including preservative or self-preserving activity.
摘要翻译： 绿色和天然衍生的杀生物剂如Nα-（C1-C22）烷酰基二碱性氨基酸烷基（C1至C22）酯盐阳离子分子可以与通常不被认为具有显着杀生物活性的阴离子分子组合以提供抗微生物，抗菌， 和/或具有多功能益处的抗真菌性质，包括防腐或自我保护活性。
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公开(公告)号：US07276109B2
公开(公告)日：2007-10-02
申请号：US10813462
申请日：2004-03-30
CPC分类号： B41N3/08
摘要： Piling due to ink, paper fibers and/or clay fillers occurs frequently during an offset printing process, resulting in the deterioration in print quality and lost manual time due to the necessity to clean the equipment. It has been experimentally found that small quantities of certain high molecular weight polyethylene oxide polymers can alleviate this serious problem. However, the overall effectiveness will depend on the concentration of the total make-up of component in the fountain solution.
摘要翻译： 由于油墨，纸纤维和/或粘土填料在胶版印刷过程中经常发生打桩，导致打印质量下降，并且由于需要清洁设备而损失手动时间。 实验发现，少量某些高分子量聚环氧乙烷聚合物可以缓解这个严重问题。 然而，整体效能将取决于喷泉溶液中组分的总组成的浓度。
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公开(公告)号：US4891423A
公开(公告)日：1990-01-02
申请号：US325872
申请日：1989-03-20
申请人： Richard F. Stockel
发明人： Richard F. Stockel
CPC分类号： A61L2/0088 , A01N47/44 , A61L12/142 , C08G73/00 , C08G73/024
摘要： Linear, polymeric polyoxyalkylenediamine biguanide or water soluble salt thereof. The biguanide is useful as a biocide in bactericidal and fungicidal compositions and is especially useful as the active ingredient in ophthalmic compositions.
摘要翻译： 线性聚合物，聚氧化亚烷基二胺双胍或其水溶性盐。 双胍可用作杀菌和杀真菌组合物中的杀生物剂，并且特别用作眼用组合物中的活性成分。
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17.发明授权Use of selenium-containing compounds for negating the toxic effects of gold compounds used in the treatment of rheumatoid arthritis, and a novel selenium-containing gold compound and use thereof as an anti-rheumatoid arthritis medicine 失效使用含硒化合物来抵消用于治疗类风湿性关节炎的金化合物的毒性作用，以及新颖的含硒金化合物及其作为抗类风湿关节炎药物的用途
公开(公告)号：US4680286A
公开(公告)日：1987-07-14
申请号：US735424
申请日：1985-04-09
CPC分类号： C07H23/00 , A61K33/04 , A61K33/24 , C07C391/00 , C07F9/5045
摘要： The toxic effects of gold compounds used in the treatment of rheumatoid arthritis can be negated by the use of a selenium-containing compound. A new selenium-containing gold compound has been found to be useful as a gold compound type anti-rheumatoid arthritis medicine which can self-detoxify gold toxicity.
摘要翻译： PCT No.PCT / US83 / 01239 Sec。 371日期：1985年4月9日 102（e）1985年4月9日PCT 1983年8月10日提交。用于治疗类风湿性关节炎的金化合物的毒性作用可以通过使用含硒化合物而被否定。 已经发现新的含硒金化合物可用作金化合物类抗风湿性关节炎药物，其可以自我解毒金毒性。
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18.发明授权
公开(公告)号：US4654208A
公开(公告)日：1987-03-31
申请号：US700745
申请日：1985-02-12
申请人： Richard F. Stockel , Murray Jelling
发明人： Richard F. Stockel , Murray Jelling
CPC分类号： A61L12/145 , A01N59/00 , A61L12/102
摘要： An anti-microbial composition comprises an aqueous solution of a germicidal polymeric nitrogen compound and an oxidizing agent which potentiates the activity of the compound. The polymeric nitrogen compound includes a germicidal quaternary ammonium compound or a polyguanide compound. The oxidizing agent has a standard reduction potential between 0.85 and 2.0 volts, is soluble in water, non-toxic and enhances the activity germicidal of the nitrogen polymer at low concentrations. Suitable oxidizing agents include halogen oxides, oxyhalogens, halogens, and inorganic and organic peroxides.
摘要翻译： 抗微生物组合物包含杀菌性聚合氮化合物的水溶液和增强化合物活性的氧化剂。 聚合氮化合物包括杀菌季铵化合物或聚胍化合物。 氧化剂的标准还原电位在0.85和2.0伏特之间，可溶于水，无毒，并提高氮聚合物在低浓度下的杀菌活性。 合适的氧化剂包括卤素氧化物，卤代卤素，卤素和无机和有机过氧化物。
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公开(公告)号：US4506628A
公开(公告)日：1985-03-26
申请号：US513178
申请日：1983-07-13
申请人： Richard F. Stockel
发明人： Richard F. Stockel
IPC分类号： A01K1/015
CPC分类号： A01K1/0154 , A01K1/0155
摘要： An improved and novel animal litter is described utilizing alumina, aluminosilicates or coal residues as the substrate intimately mixed with monomers containing acid functionalities which are polymerized in-situ. The resulting mixture is then extruded into pellets of any size or shape. Animal litter pellets prepared by this invention have vastly improved water adsorption properties, deodorizing capacity, and they do not have to be cured at high temperatures.
摘要翻译： 使用氧化铝，硅铝酸盐或煤渣作为底物与含有原位聚合的酸官能团的单体充分混合来描述改进和新颖的动物垃圾。 然后将所得混合物挤出成任何尺寸或形状的颗粒。 通过本发明制备的动物砂粒具有极大改善的水吸附性能，除臭能力，并且它们不必在高温下固化。
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20.发明授权
公开(公告)号：US4499077A
公开(公告)日：1985-02-12
申请号：US471011
申请日：1983-03-01
申请人： Richard F. Stockel , Murray Jelling
发明人： Richard F. Stockel , Murray Jelling
CPC分类号： A61L12/145 , A01N59/00 , A61L12/102
摘要： An anti-microbial composition is provided comprising an aqueous solution of an oxyhalogen compound and a polymeric germicide. The oxyhalogen compound is preferably stabilized chlorine dioxide and the polymeric germicide is preferably a quaternary ammonium compound such as a copolymer of at least one difunctional tertiary amine and a dihalo organic compound such as 1,4-dihalo-2-butene, a copolymer of at least one difunctional tertiary amine, at least one monofunctional tertiary amine and a dihalo organic compound such as 1,4-dihalo-2-butene, or a polyguanide such as hydrochloride salt of poly(hexamethylene biguanide). The anti-microbial composition thus formed is used for the treatment of soft contact lenses to disinfect the same with an optimum effect while minimizing the irritant possibilities thereof and also minimizing absorption of the composition into the porous and hydrophilic surfaces of soft contact lenses such that there is a minimal release of absorbed substances after treatment.
摘要翻译： 提供了包含卤氧化合物和聚合杀菌剂的水溶液的抗微生物组合物。 卤代卤化合物优选是稳定的二氧化氯，并且聚合杀菌剂优选为季铵化合物，例如至少一种二官能叔胺和二卤代有机化合物如1,4-二卤代-2-丁烯的共聚物， 至少一个双官能叔胺，至少一个单官能叔胺和二卤代有机化合物如1,4-二卤代-2-丁烯，或聚胍如聚（六亚甲基双胍）的盐酸盐。 如此形成的抗微生物组合物用于治疗软性隐形眼镜以最佳效果对其进行消毒，同时最小化其刺激性可能性，并且还使组合物吸收到软性隐形眼镜的多孔和亲水表面中，使得 是治疗后吸收物质的最小释放。
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