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公开(公告)号：US20130136832A1
公开(公告)日：2013-05-30
申请号：US13065972
申请日：2011-04-04
IPC分类号： A23L3/3544 , C07C229/00 , C07D233/54 , C07D209/04 , A23L3/3526 , C07C229/26
CPC分类号： A23L3/3526 , A23L3/3508 , A23L3/3544 , C07D209/04 , C07D233/54
摘要： This invention discloses a method of preservation of a food product comprising the step of adding 1) a first component comprising between 10 ppm and 1% of a biocidal salt of Nα—(C1-C22) alkanoyl di-basic amino acid alkyl (C1-C22) ester cationic biocidal molecule with an anionic counterion, and 2) a second component comprising from 10 ppm to 1% by weight an acyl monoglyceride, directly to a food product. The preferred cationic biocidal molecule comprises Nα-lauroyl-L-arginine ethyl ester (“LAE”). The invention also discloses the method of preservation of a food product using salts of a Nα—(C1-C22) alkanoyl di-basic amino acid alkyl (C1-C22) ester cationic biocidal molecule and an anionic counterion with or without a monoglyceride of a fatty acid, whereby the packaging film is compounded with the salts and the optional monoglyceride of a fatty acid.
摘要翻译： 本发明公开了一种保存食品的方法，包括以下步骤：加入1）包含10ppm至1％的Nalpha-（C1-C22）烷酰基二碱性氨基酸烷基（C1- C22）具有阴离子抗衡离子的酯阳离子杀生物分子，和2）包含10ppm至1重量％的酰基单甘油酯的第二组分，直接与食品接触。 优选的阳离子杀生物分子包括Nalpha-月桂酰-L-精氨酸乙酯（“LAE”）。 本发明还公开了使用Nalpha-（C1-C22）烷酰基二碱性氨基酸烷基（C1-C22）酯阳离子杀生物分子的盐和具有或不具有单酸甘油酯的阴离子抗衡离子的食品来保存食品的方法 脂肪酸，由此将包装膜与脂肪酸的盐和任选的甘油单体混合。
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公开(公告)号：US08193244B1
公开(公告)日：2012-06-05
申请号：US12455197
申请日：2009-05-28
IPC分类号： A61K31/215 , A61K31/24 , A61K8/02 , A01N25/00
CPC分类号： A61K31/23 , A01N37/46 , A61K8/375 , A61K8/44 , A61K9/0036 , A61K31/223 , A61K2800/10 , A61K2800/524 , A61Q19/00 , A61K2300/00 , A01N37/02
摘要： The combination of Nα-long chain alkanoyl di basic amino acid alkyl ester salts with glycerol monofatty acid esters results in biocidal synergy and the extension of cidal activity of the di basic amino acid derivative for a variety of antimicrobial applications like oral care, wound care, dermatological care, animal care, and cosmetic applications.Nα-C8-C14-long chain alkanoyl-L-arginine alkyl (C1-C4 short chain) ester salts with glycerol monofatty acid esters (C8-C14) are very effective as antimicrobial agents for hospital use particularly as a coating for surgical drapes, covers, walls, trays, table tops, gurneys, or the like. Other uses include the treatment of HSV-1 (fever sore) and as a microbicide when using the combination of the di basic amino acid ester derivative with glycerol monofatty acid esters for preventing HIV and STD's.
摘要翻译： Nα-长链烷酰基二碱性氨基酸烷基酯盐与甘油单脂肪酸酯的组合导致了杀生物的协同作用和二碱性氨基酸衍生物的杀螨活性的延长，用于各种抗微生物应用，如口腔护理，伤口护理， 皮肤病护理，动物护理和化妆品应用。 具有甘油单脂肪酸酯（C8-C14）的Nα-C8-C14-长链烷酰基-L-精氨酸烷基（C1-C4短链）酯盐作为用于医院用途的抗微生物剂是非常有效的，特别是作为外科用膜的涂层， 盖子，墙壁，托盘，桌面，轮辋等。 其他用途包括治疗HSV-1（发烧疮），并且当使用二碱性氨基酸酯衍生物与甘油单脂肪酸酯组合以预防HIV和STD时，作为杀微生物剂。
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公开(公告)号：US20100056628A1
公开(公告)日：2010-03-04
申请号：US12589155
申请日：2009-10-19
IPC分类号： A01N37/12 , C07C229/02 , A01P15/00
CPC分类号： A01N25/30 , A23B4/10 , A23B4/20 , C07C229/26 , C07C279/14 , A01N37/46 , A01N43/38 , A01N43/50 , A01N47/44
摘要： Green and naturally derived biocides such as Nα—(C1-C22) alkanoyl di basic amino acid alkyl (C1 to C22) ester salt cationic molecules can be combined with an anionic molecule not generally considered as having significant biocidal activity to provide antimicrobial, antibacterial, and/or antifungal properties with multifunctional benefits including preservative or self-preserving activity.
摘要翻译： 绿色和天然衍生的杀生物剂如Nα-（C1-C22）烷酰基二碱性氨基酸烷基（C1至C22）酯盐阳离子分子可以与通常不被认为具有显着杀生物活性的阴离子分子组合以提供抗微生物，抗菌， 和/或具有多功能益处的抗真菌性质，包括防腐或自我保护活性。
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公开(公告)号：US08834857B1
公开(公告)日：2014-09-16
申请号：US13374856
申请日：2012-01-18
IPC分类号： A61Q19/00 , A61Q19/10 , A61Q15/00 , A61K31/215 , C07C69/02
CPC分类号： C11D3/502 , A61K8/362 , A61K8/416 , A61K8/44 , A61K8/8141 , A61K2300/00 , A61L2300/602 , A61Q15/00 , A61Q19/00 , A61Q19/10
摘要： A method for cleaning, benefiting, or deodorizing skin or hair utilizing a body wash, skin cleaner, soap, shampoo or deodorizer formulation containing a controlled release skin benefit or deodorizing salt, a hydrophilic moisturizing polymer and surfactants is described. The method imparts benefits or deodorizing agents to the skin or hair and maintains effective levels for an extended period.
摘要翻译： 描述了使用沐浴露，皮肤清洁剂，肥皂，洗发剂或除臭剂制剂来清洗，吸收或除臭皮肤或毛发的方法，其含有控制释放的皮肤益处或除臭盐，亲水性保湿聚合物和表面活性剂。 该方法赋予皮肤或头发的益处或除臭剂，并在长时间内维持有效水平。
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公开(公告)号：US08795638B1
公开(公告)日：2014-08-05
申请号：US13200997
申请日：2011-10-06
CPC分类号： A61K31/4425 , A61K6/0017 , A61K6/0023 , A61K8/347 , A61K8/43 , A61K8/8135 , A61K31/14 , A61K31/155 , A61K45/06 , A61Q11/00 , C08L33/10 , C08L71/02 , C08L31/04 , C08L29/04
摘要： This invention pertains to dental care compositions with antimicrobial benefits. In particular, the invention provides for compositions of oral tissue-adherent salts that release biocidal ions on a controlled release basis and thereby provide and maintain an essentially uniform concentration of biocidal ions above the MBC or MIC of the target bacteria at the site of application in the mouth for an extended period of time. The compositions are useful for treating or preventing oral diseases resulting from bacteria, fungal or yeast infections, such as caries, gingivitis, periodontal disease and candidiasis.
摘要翻译： 本发明涉及具有抗菌益处的牙科护理组合物。 特别地，本发明提供了口服组织粘附盐的组合物，其在受控释放的基础上释放杀生物离子，从而在施用位置提供并保持在靶细菌的MBC或MIC上方的基本均匀浓度的杀生物离子浓度 嘴巴长时间的流逝。 该组合物可用于治疗或预防由细菌，真菌或酵母菌感染引起的口腔疾病，例如龋齿，牙龈炎，牙周病和念珠菌病。
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公开(公告)号：US07074459B2
公开(公告)日：2006-07-11
申请号：US10443721
申请日：2003-05-23
申请人： Richard F. Stockel
发明人： Richard F. Stockel
CPC分类号： A01N57/34 , A01N33/12 , A01N47/44 , B27K3/15 , B27K3/34 , B27K3/38 , B27K3/50 , C08L79/02 , C08L97/02 , A01N47/14 , A01N43/78 , A01N43/40 , A01N37/44 , A01N37/02 , A01N31/14 , A01N2300/00
摘要： A method for preserving wood which comprises contacting the wood with a complex of a cationic monomeric or polymeric biocide and an anionic monomeric or polymeric biocide. Insoluble complexes may solubilized in water in the form of an emulsion or microemulsion by adding a nonionic and/or amphoteric surfactant and/or aqueous cosolvent to the complex. Suitable cationic biocides are those that contain functionalities such as amidine, guanidine, biguanide, quaternary, phosphonium, sulfonium and gemini quaternary functionalities. Suitable anionic biocides include: phenolics; saturated, unsaturated or substituted carboxylates; organomercaptide; tetrathiocarbonates; cyanodithioimidocarbamates; dithiodialkylcarbamates; anionic oxides of transition metals; aminocarboxylic acids; aminoorganophosphonic acids; monoalkyl phosphates; dialkylphosphates; and substituted or unsubstituted 2-hydroxy-2,4,6-cycloheptatrianone.
摘要翻译： 一种保护木材的方法，其包括将木材与阳离子单体或聚合物杀生物剂和阴离子单体或聚合物杀生物剂的配合物接触。 通过向络合物中加入非离子和/或两性表面活性剂和/或水溶性助溶剂，不溶性络合物可以以乳液或微乳液的形式溶解在水中。 合适的阳离子杀生物剂是含有诸如脒，胍，双胍，季，鏻，锍和双子二级官能团等功能的阳离子杀生物剂。 合适的阴离子杀生物剂包括：酚类; 饱和的，不饱和的或取代的羧酸盐; 有机基体 四硫代碳酸酯; 氰基二硫代氨基甲酸酯; 二硫代二烷基氨基甲酸酯; 过渡金属的阴离子氧化物; 氨基羧酸; 氨基有机膦酸; 磷酸单烷基酯; 磷酸二烷基酯; 和取代或未取代的2-羟基-2,4,6-环庚胺酮酮。
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公开(公告)号：US06426064B1
公开(公告)日：2002-07-30
申请号：US09478273
申请日：2000-01-05
申请人： Richard F. Stockel , Robin Davidson
发明人： Richard F. Stockel , Robin Davidson
IPC分类号： A61K706
CPC分类号： A61Q5/00 , A61K8/8135 , A61K8/88 , A61Q5/06
摘要： Cosmetic compositions containing in a mostly aqueous medium, a highly charged anionic water-soluble polymer and a polyamino acid, and their use in the treatment of keratinous materials.
摘要翻译： 含有大部分含水介质，高电荷阴离子水溶性聚合物和聚氨基酸的化妆品组合物及其在治疗角质材料中的用途。
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公开(公告)号：US5281414A
公开(公告)日：1994-01-25
申请号：US387077
申请日：1989-07-28
申请人： Richard F. Stockel
发明人： Richard F. Stockel
摘要： What is provided herein is a three-dimensional water disinfectant composition comprising the reaction product of a cross-linked, anti-microbial organosilicon quaternary ammonium salt and a macroporous cationic exchange resin. The cross-linked organosilicon quaternary ammonium salt suitably comprises about 2 to 60% by weight of the composition and the ion-exchange resin about 40 to 98% by weight of the composition. In a preferred form of the invention, the organosilicon compound constitutes about 20 to 40% by weight of the composition. Such compositions exhibit broad spectrum anti-bacteria activity including gram-negative activity, and are active algicidally in preventing the growth of algae in the water. The ion-exchange resin preferably is either a weak or strong cationic macroreticular ion-exchange resin. Methods of making such compositions also are described herein.
摘要翻译： 本文提供的是包含交联的抗微生物有机硅季铵盐和大孔阳离子交换树脂的反应产物的三维水消毒剂组合物。 交联的有机硅季铵盐合适地包含组合物的约2至60重量％和离子交换树脂占组合物重量的约40至98重量％。 在本发明的优选形式中，有机硅化合物构成组合物的约20至40重量％。 这样的组合物显示出广谱的抗细菌活性，包括革兰氏阴性活性，并且在防止水中藻类的生长中是致死活性的。 离子交换树脂优选为弱阳离子或强阳离子大网络离子交换树脂。 制备这种组合物的方法也在本文中描述。
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公开(公告)号：US4039501A
公开(公告)日：1977-08-02
申请号：US582333
申请日：1975-05-30
CPC分类号： A61Q19/00 , A61K8/8152 , C08K5/17
摘要： Plasticized solid, water-insoluble, water-swellable, hydrophilic polymers having the recurring unit ##STR1## wherein R is a divalent aliphatic hydrocarbon radical of 2 to 8 carbon atoms; where R' is hydrogen or alkyl of 1 to 4 carbon atoms; preferably hydrogen or methyl; wherein R" is hydrogen or alkyl of 1 to 12 carbon atoms; and wherein n is an integer of at least 1; and as the plasticizer therefor, preferably a liquid compound characterized by amino and hydroxyl groups, said compound having a relatively low vapor pressure.
摘要翻译： 具有重复单元的增塑固体，水不溶性，水溶胀性亲水聚合物，其中R是2至8个碳原子的二价脂族烃基; 其中R'是氢或1-4个碳原子的烷基; 优选氢或甲基; 其中R“为氢或1至12个碳原子的烷基; 并且其中n为至少1的整数; 作为其增塑剂，优选以氨基和羟基为特征的液体化合物，所述化合物具有较低的蒸气压。
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公开(公告)号：US20200275663A1
公开(公告)日：2020-09-03
申请号：US16799259
申请日：2020-02-24
摘要： An aqueous oral spray designed to treat mouth guards against bacterial infection comprising: 1. A naturally derived di-basic amino acid derivative, 2. A natural sweetener which inhibits the adhesion of bacteria to the oral cavity and, 3. Optionally a natural flavor and/or natural dye 4. Optionally a mouth guard surface modified to absorb specific components of above oral aqueous solution so as to render mouth guard more effective overtime in inhibiting microorganism growth on surface and in contact with mouth surfaces compared with unmodified mouth guard surface.
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