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公开(公告)号:US08242239B2
公开(公告)日:2012-08-14
申请号:US12544117
申请日:2009-08-19
CPC分类号: C07K14/4748
摘要: The invention relates to a tumor-associated peptide with an amino acid sequence selected from the group consisting of SEQ ID NO. 1 to SEQ ID NO. 577 from the attached sequence protocol, the peptide being capable of binding to a molecule of the human major histocompatibility complex (MHC) class I. The invention further relates to the use of the peptides for preparation of a drug and for the treatment of tumor diseases and/or adenomatous diseases. Furthermore, a pharmaceutical composition is described comprising at least one of the peptides.
摘要翻译: 本发明涉及具有选自SEQ ID NO:1的氨基酸序列的肿瘤相关肽。 1至SEQ ID NO。 577,该肽能够结合人类主要组织相容性复合物(MHC)I类的分子。本发明还涉及该肽用于制备药物和用于治疗肿瘤疾病的用途 和/或腺瘤性疾病。 此外,描述了包含至少一种肽的药物组合物。
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公开(公告)号:US08008431B2
公开(公告)日:2011-08-30
申请号:US11596802
申请日:2005-05-24
CPC分类号: C07K14/4748
摘要: The invention relates to a tumor-associated peptide with an amino acid sequence selected from the group consisting of SEQ ID NO. 1 to SEQ ID NO. 577 from the attached sequence protocol, the peptide being capable of binding to a molecule of the human major histocompatibilityg complex (MHC) class I. The invention further relates to the use of the peptides for preparation of a drug and for the treatment of tumor diseases and/or adenomatous diseases. Furthermore, a pharmaceutical composition is described comprising at least one of the peptides.
摘要翻译: 本发明涉及具有选自SEQ ID NO:1的氨基酸序列的肿瘤相关肽。 1至SEQ ID NO。 577,该肽能够结合人类主要组织相容性复合物(MHC)I类的分子。本发明还涉及肽用于制备药物和治疗肿瘤疾病的用途 和/或腺瘤性疾病。 此外,描述了包含至少一种肽的药物组合物。
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公开(公告)号:US20100021441A1
公开(公告)日:2010-01-28
申请号:US12544117
申请日:2009-08-19
CPC分类号: C07K14/4748
摘要: The invention relates to a tumor-associated peptide with an amino acid sequence selected from the group consisting of SEQ ID NO. 1 to SEQ ID NO. 577 from the attached sequence protocol, the peptide being capable of binding to a molecule of the human major histocompatibility complex (MHC) class I. The invention further relates to the use of the peptides for preparation of a drug and for the treatment of tumor diseases and/or adenomatous diseases. Furthermore, a pharmaceutical composition is described comprising at least one of the pepti
摘要翻译: 本发明涉及具有选自SEQ ID NO:1的氨基酸序列的肿瘤相关肽。 1至SEQ ID NO。 577,该肽能够结合人类主要组织相容性复合物(MHC)I类的分子。本发明还涉及该肽用于制备药物和用于治疗肿瘤疾病的用途 和/或腺瘤性疾病。 此外,描述了包含至少一个该肽的药物组合物
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公开(公告)号:US07087712B1
公开(公告)日:2006-08-08
申请号:US10019513
申请日:2000-03-28
CPC分类号: C07K14/4727 , A61K39/00 , A61K48/00 , A61K2039/53
摘要: The invention relates to a peptide for triggering an immune response to tumor cells. Said peptide has an optionally modified fragment of the protein that is encoded by the gene MUC-1. Said protein triggers an HLA-A2-restricted immune response.
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