公开(公告)号：US11229912B2

公开(公告)日：2022-01-25

申请号：US16605706

申请日：2018-03-27

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Viktor Shkolnikov ,  Alexander Govyadinov ,  Pavel Kornilovich ,  Erik D. Torniainen

IPC: B01L3/00 ,  G01N1/40

Abstract: An example system includes an input channel having a first end and a second end to receive particles through the first end, a separation chamber, at least two output channels, and an integrated pump to facilitate flow through the separation chamber. The separation chamber is in fluid communication with the second end of the input channel. The separation chamber has a passive separation structure, the passive separation structure including an array of columns spaced apart to facilitate separation of particles in a flow based on a size of the particles. Each output channel is in fluid communication with the separation chamber to receive separated particles. The integrated pump is positioned within at least one of the input channel or one of the at least two output channels.

公开(公告)号：US20210292819A1

公开(公告)日：2021-09-23

申请号：US17059773

申请日：2018-12-13

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Ryan Murphy ,  Alexander Govyadinov

IPC: C12Q1/6825 ,  C12Q1/6837 ,  G01N27/327

Abstract: A multiplex nucleic acid detection system includes an electrochemical cell and a nucleic acid amplifying fluid. The electrochemical cell includes a reference electrode, a first surface-modified redox electrode including a first working redox electrode with a first surface-attached nucleic acid oligomer attached to the first working electrode, a second surface-modified redox electrode including a second working electrode with a second surface-attached nucleic acid oligomer attached to the second working electrode that is different than the first surface-attached nucleic acid oligomer, and a counter-electrode. The nucleic acid amplifying fluid in this example includes a first dispersed nucleic acid oligomer having a complimentary reverse orientation relative to the first surface-attached nucleic acid oligomer, a second dispersed nucleic acid oligomer having a complimentary reverse orientation relative to the second surface-attached nucleic acid oligomer, and a redox-active compound having affinity to the nucleic acid.

公开(公告)号：US20210239634A1

公开(公告)日：2021-08-05

申请号：US17049166

申请日：2018-08-09

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander Govyadinov ,  Viktor Shkolnikov

IPC: G01N27/02 ,  B01L3/00 ,  G01N1/28

Abstract: In one example in accordance with the present disclosure, a sample Sample Preparation System preparation system is described. The system includes a reaction chamber to hold at least one fluid. An inlet impedance sensor of the system detects a level of conductivity through at least one inlet of the reaction chamber and an outlet impedance sensor detects a level of conductivity through at least one outlet of the reaction chamber. A controller of the system, based on measured levels of conductivity, determines a state of a reaction within the reaction chamber.

公开(公告)号：US10946649B2

公开(公告)日：2021-03-16

申请号：US16067304

申请日：2016-04-29

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Alexander Govyadinov ,  Craig Olbrich

IPC: B41J2/14 ,  C09D11/023 ,  C09D11/36 ,  B41J2/01 ,  C09D11/30 ,  C09D11/38 ,  B41J2/21

Abstract: In an example implementation, a method of printing with an emulsion, includes generating an emulsion of non-water based fluid and water based fluid on a printhead, and ejecting the emulsion through a printhead nozzle.

公开(公告)号：US20210023852A1

公开(公告)日：2021-01-28

申请号：US17065831

申请日：2020-10-08

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Alexander Govyadinov ,  Erik D. Torniainen ,  David P. Markel

IPC: B41J2/18 ,  B41J2/14 ,  B41J2/175 ,  F04B19/00 ,  F04B19/20 ,  F04B19/24 ,  B01L3/00

Abstract: A fluid ejection device may include a first channel having a first end and a second end, a first drop ejector along the first channel, a second channel having a first end and a second end, a second drop ejector along the second channel, a third channel extending between and connecting the first end of the first channel and the first end of the second channel, a fourth channel extending between and connecting the second end of the firs channel and the second end of the second channel and a fifth channel extending between and connecting the third channel and the fourth channel.

公开(公告)号：US20210010488A1

公开(公告)日：2021-01-14

申请号：US16493344

申请日：2017-04-07

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Erik D. Torniainen ,  Alexander Govyadinov ,  Pavel Kornilovich ,  David P. Markel

IPC: F04F7/00 ,  F04B53/10 ,  B01L3/00 ,  B81B1/00

Abstract: The present disclosure is drawn to inertial pumps. An inertial pump can include a microfluidic channel, a fluid actuator located in the microfluidic channel, and a check valve located in the microfluidic channel. The check valve can include a moveable valve element, a narrowed channel segment located upstream of the moveable valve element, and a blocking element formed in the microfluidic channel downstream of the moveable valve element. The narrowed channel segment can have a width less than a width of the moveable valve element so that the moveable valve element can block fluid flow through the check valve when the moveable valve element is positioned in the narrowed channel segment. The blocking element can be configured such that the blocking element constrains the moveable valve element within the check valve while also allowing fluid flow when the moveable valve element is positioned against the blocking element.

公开(公告)号：US20200223225A1

公开(公告)日：2020-07-16

申请号：US16834546

申请日：2020-03-30

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander Govyadinov ,  Paul A. Richards ,  Chris Bakker

IPC: B41J2/045 ,  B41J2/175 ,  B41J2/14 ,  B41J2/18

Abstract: A fluid ejection device includes a fluid slot, at least one fluid ejection chamber communicated with the fluid slot, a drop ejecting element within the at least one fluid ejection chamber, a fluid circulation channel communicated with the fluid slot and the at least one fluid ejection chamber, and a fluid circulating element communicated with the fluid circulation channel. The fluid circulating element is to provide on-demand circulation of fluid from the fluid slot through the fluid circulation channel and the at least one fluid ejection chamber.

公开(公告)号：US10655994B2

公开(公告)日：2020-05-19

申请号：US15546327

申请日：2015-04-30

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander Govyadinov ,  Erik D Torniainen ,  Pavel Kornilovich

IPC: G01F1/684 ,  B41J2/125 ,  B01L3/00 ,  G01F1/69 ,  G01F1/698 ,  B41J2/175

Abstract: An apparatus includes a microfluidic channel and a flow sensor along the microfluidic channel. The flow sensor includes a heat emitting resistor for connection to an electric current source, analytical parameter sensor and electronics. The heat emitting resistor has a resistance that varies in response to temperature. The electrical parameter sensor is to sense an electrical parameter of the heat emitting resistor that is based on the resistance of the heat emitting resistor. The electronics determine a flow based on the sensed electrical parameter.

公开(公告)号：US20200031135A1

公开(公告)日：2020-01-30

申请号：US16337579

申请日：2017-01-23

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Tsuyoshi Yamashita ,  Alexander Govyadinov ,  Nick McGuinness ,  Erik D Torniainen ,  David P Markel

IPC: B41J2/18

Abstract: A fluid ejection device includes a fluid slot, two laterally adjacent fluid ejection chambers each communicated with the fluid slot and having a drop ejecting element therein, and a fluid circulation path communicated with each of the two laterally adjacent fluid ejection chambers and having a fluid circulating element therein, with the two laterally adjacent fluid ejection chambers to concurrently eject drops of fluid therefrom such that the drops of fluid are to coalesce during flight.

公开(公告)号：US20190381793A1

公开(公告)日：2019-12-19

申请号：US16343303

申请日：2017-01-31

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Tracy A Lang ,  Alexander Govyadinov

IPC: B41J2/14 ,  B41J2/175

Abstract: A fluid ejection device includes a fluid ejection chamber having a drop ejecting element therein, a first fluid channel to communicate a first fluid with the fluid ejection chamber, a second fluid channel to communicate a second fluid different than the first fluid with the fluid ejection chamber, and a fluid pump communicated with one of the first fluid channel and the second fluid channel. As such, the fluid ejection chamber is to selectively eject drops of the first fluid, the second fluid, and a combination of the first fluid and the second fluid therefrom.