Particle categorization
    3.
    发明授权

    公开(公告)号:US11686664B2

    公开(公告)日:2023-06-27

    申请号:US16768878

    申请日:2018-01-29

    Abstract: An example system includes an input channel having a first end and a second end to receive particles through the first end, a sensor to categorize particles in the input channel into one of at least two categories, and at least two output channels Each output channel is coupled to the second end of the input channel to receive particles from the input channel, and each output channel is associated with at least one category of the at least two categories. Each output channel has a corresponding pump operable, based on the categorization of a detected particle in a category associated with a different output channel, to selectively slow, stop, or reverse a flow of particles into the output channel from the input channel.

    MICROFLUIDIC DEVICES
    6.
    发明申请

    公开(公告)号:US20220118450A1

    公开(公告)日:2022-04-21

    申请号:US17417500

    申请日:2019-04-30

    Abstract: The present disclosure relates to a microfluidic device including a microfluidic substrate and dry reagent-containing particles. The microfluidic substrate includes an ingress microfluidic channel that fluidly feeds an egress microfluidic channel through a microfluidic-retaining region that includes a microfluidic discontinuity feature, a particle-retaining chemical coating, or a combination thereof. The dry reagent-containing particles include a reagent that is releasable from the dry reagent-containing particles when exposed to a release fluid. The dry reagent-containing particles are retained within the microfluidic substrate at the microfluidic discontinuity feature or particle-retaining chemical coating in position to release the reagent into the egress microfluidic channel upon flow of release fluid from the ingress microfluidic channel through the microfluidic-retaining region.

    Fluidic channels for microfluidic devices

    公开(公告)号:US11278891B2

    公开(公告)日:2022-03-22

    申请号:US15763402

    申请日:2015-09-25

    Abstract: Example fluidic channels for microfluidic devices are disclosed. In examples disclosed herein, an example microfluidic device includes a body having a microfluidic network. The microfluidic network includes a main fluid channel to transport a biological fluid from a first cavity of the microfluidic network to a second cavity of the microfluidic network. An auxiliary fluid channel is in fluid communication with to the main fluid channel. The auxiliary fluid channel has a first end and a second end. The first end is in fluid communication with the main fluid channel and the second end is spaced from the main fluid channel. A fluid actuator is positioned in the auxiliary fluid channel to induce fluid flow in the main fluid channel.

    CHEMICAL LYSIS SYSTEMS
    9.
    发明申请

    公开(公告)号:US20220073863A1

    公开(公告)日:2022-03-10

    申请号:US17417339

    申请日:2019-02-01

    Abstract: In one example in accordance with the present disclosure, a chemical lysis system is described. The chemical lysis system includes a microfluidic channel to serially feed individual cells from a volume of cells to at least one chemical lysing device. Each chemical lysing device includes at least one lysing chamber to receive, from the microfluidic channel, a single cell to be lysed. The chemical lysing device also includes an orifice disposed in each lysing chamber to receive a lysing agent and a sensor to detect a state within the lysing chamber. A controller of the chemical lysis system analyzes a ruptured cell.

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