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    Particle categorization
    5.
    发明授权
    Particle categorization 有权

    公开(公告)号：US11686664B2

    公开(公告)日：2023-06-27

    申请号：US16768878

    申请日：2018-01-29

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： Alexander Govyadinov ,  Pavel Kornilovich

    IPC: G01N15/14 ,  B01L3/00 ,  G01N15/10 ,  H10N30/20

    CPC classification number: G01N15/1484 ,  B01L3/50273 ,  H10N30/2047 ,  G01N2015/1006 ,  G01N2015/1081

    Abstract: An example system includes an input channel having a first end and a second end to receive particles through the first end, a sensor to categorize particles in the input channel into one of at least two categories, and at least two output channels Each output channel is coupled to the second end of the input channel to receive particles from the input channel, and each output channel is associated with at least one category of the at least two categories. Each output channel has a corresponding pump operable, based on the categorization of a detected particle in a category associated with a different output channel, to selectively slow, stop, or reverse a flow of particles into the output channel from the input channel.

    Fluidic channels for microfluidic devices
    7.
    发明授权
    Fluidic channels for microfluidic devices 有权

    公开(公告)号：US11278891B2

    公开(公告)日：2022-03-22

    申请号：US15763402

    申请日：2015-09-25

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： Alexander Govyadinov ,  Erik D. Torniainen ,  Pavel Kornilovich ,  David P. Markel

    IPC: B81B1/00 ,  B01L3/00

    Abstract: Example fluidic channels for microfluidic devices are disclosed. In examples disclosed herein, an example microfluidic device includes a body having a microfluidic network. The microfluidic network includes a main fluid channel to transport a biological fluid from a first cavity of the microfluidic network to a second cavity of the microfluidic network. An auxiliary fluid channel is in fluid communication with to the main fluid channel. The auxiliary fluid channel has a first end and a second end. The first end is in fluid communication with the main fluid channel and the second end is spaced from the main fluid channel. A fluid actuator is positioned in the auxiliary fluid channel to induce fluid flow in the main fluid channel.

    Particle separation
    8.
    发明授权
    Particle separation 有权

    公开(公告)号：US11229912B2

    公开(公告)日：2022-01-25

    申请号：US16605706

    申请日：2018-03-27

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： Viktor Shkolnikov ,  Alexander Govyadinov ,  Pavel Kornilovich ,  Erik D. Torniainen

    IPC: B01L3/00 ,  G01N1/40

    Abstract: An example system includes an input channel having a first end and a second end to receive particles through the first end, a separation chamber, at least two output channels, and an integrated pump to facilitate flow through the separation chamber. The separation chamber is in fluid communication with the second end of the input channel. The separation chamber has a passive separation structure, the passive separation structure including an array of columns spaced apart to facilitate separation of particles in a flow based on a size of the particles. Each output channel is in fluid communication with the separation chamber to receive separated particles. The integrated pump is positioned within at least one of the input channel or one of the at least two output channels.

    Object focusing
    9.
    发明授权
    Object focusing 有权

    公开(公告)号：US11141729B2

    公开(公告)日：2021-10-12

    申请号：US16605162

    申请日：2018-01-24

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： Viktor Shkolnikov ,  Alexander N. Govyadinov ,  Pavel Kornilovich

    IPC: B01L3/00 ,  F04B19/00

    Abstract: An object focuser may include a substrate, a sample fluid passage supported by the substrate, a first inertial pump supported by the substrate to pump a sample fluid entraining an object through the sample fluid passage, a first sheath fluid passage, a second inertial pump supported by the substrate to pump a first sheath fluid through the first sheath fluid passage, a second sheath fluid passage and a second inertial pump supported by the substrate to pump a second sheath fluid through the second sheath fluid passage. The first sheath fluid passage and the second sheath fluid passage are connected to the sample fluid passage at a convergence on opposite sides of the sample fluid passage.

    INERTIAL PUMPS
    10.
    发明申请
    INERTIAL PUMPS 有权

    公开(公告)号：US20210010488A1

    公开(公告)日：2021-01-14

    申请号：US16493344

    申请日：2017-04-07

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Erik D. Torniainen ,  Alexander Govyadinov ,  Pavel Kornilovich ,  David P. Markel

    IPC: F04F7/00 ,  F04B53/10 ,  B01L3/00 ,  B81B1/00

    Abstract: The present disclosure is drawn to inertial pumps. An inertial pump can include a microfluidic channel, a fluid actuator located in the microfluidic channel, and a check valve located in the microfluidic channel. The check valve can include a moveable valve element, a narrowed channel segment located upstream of the moveable valve element, and a blocking element formed in the microfluidic channel downstream of the moveable valve element. The narrowed channel segment can have a width less than a width of the moveable valve element so that the moveable valve element can block fluid flow through the check valve when the moveable valve element is positioned in the narrowed channel segment. The blocking element can be configured such that the blocking element constrains the moveable valve element within the check valve while also allowing fluid flow when the moveable valve element is positioned against the blocking element.

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