Uv-active binding agent
    12.
    发明申请
    Uv-active binding agent 失效
    Uv活性结合剂

    公开(公告)号:US20060148975A1

    公开(公告)日:2006-07-06

    申请号:US10532575

    申请日:2003-11-05

    IPC分类号: C09D5/02 C08F8/14

    摘要: The present invention relates to processes for preparing actinic-radiation-curable and/or dual-cure poly(meth)acrylates by preparing a poly(meth)acrylate containing hydroxy-functional side chains and transesterifying or esterifying the poly(meth)acrylate containing hydroxy-functional side chains with a (meth)acrylate or (meth)acrylic acid. The present invention further relates to the actinic-radiation-curable and/or dual-cure poly(meth)acrylates themselves and to the use of the actinic-radiation-curable and/or dual-cure poly(meth)acrylates in the preparation of dispersions or as a component in coating formulations and topcoats comprising at least one actinic-radiation-curable and/or dual-cure poly(meth)acrylate.

    摘要翻译: 本发明涉及通过制备含羟基官能侧链的聚(甲基)丙烯酸酯并酯交换或酯化含羟基的聚(甲基)丙烯酸酯而制备光化可辐射固化和/或双重固化的聚(甲基)丙烯酸酯的方法。 具有(甲基)丙烯酸酯或(甲基)丙烯酸的官能侧链。 本发明还涉及光化学辐射固化和/或双重固化的聚(甲基)丙烯酸酯本身以及使用光化学辐射固化和/或双重固化的聚(甲基)丙烯酸酯在制备 分散体或作为包含至少一种光化学辐射固化和/或双重固化的聚(甲基)丙烯酸酯的涂料配方和面漆中的组分。

    Pyrimidine low molecular weight ligands for modulating hormone receptors
    17.
    发明申请
    Pyrimidine low molecular weight ligands for modulating hormone receptors 审中-公开
    用于调节激素受体的嘧啶低分子量配体

    公开(公告)号:US20090203716A1

    公开(公告)日:2009-08-13

    申请号:US12291932

    申请日:2008-11-14

    IPC分类号: A61K31/519 C07D495/04

    CPC分类号: A61K31/519 C07D495/04

    摘要: Disclosed herein are small molecule modulators hormone receptors, including agonists and antagonists of luteinizing hormone/choriogonadotropin, follicle stimulating hormone and thyroid stimulating hormone receptors. Exemplary disclosed compounds include those of the formula wherein X is —S(O)nR5; n is 0, 1 or 2; Y is —OR6 or —NR7R8 R1 and R2 independently are selected from optionally substituted lower aliphatic, alkoxy, aralkyl, halogen, H and —OR5, wherein R5 is selected from lower alkyl, H, aralkyl, acyl, alkoxycarbonyl and aminocarbonyl; R3 and R4 independently are selected from acyl, alkoxycarbonyl, aminocarbonyl, aralkyl, H, lower alkyl and cycloalkyl; R5 is selected from lower alkyl, aralkyl, cycloalkyl and haloalkyl; R6 is selected from H, lower alkyl and aralkyl; R7 and R8 independently are selected from H, lower alkyl, aralkyl and cycloalkyl.

    摘要翻译: 本文公开了小分子调节剂激素受体,包括促黄体激素/促性腺激素的激动剂和拮抗剂,促卵泡激素和促甲状腺激素受体。 示例性公开的化合物包括下式的那些化合物其中X是-S(O)n R 5; n为0,1或2; Y是-OR 6或-NR 7 R 8 R 1和R 2独立地选自任选取代的低级脂族,烷氧基,芳烷基,卤素,H和-OR 5,其中R 5选自低级烷基,H,芳烷基,酰基,烷氧基羰基和氨基羰基。 R3和R4独立地选自酰基,烷氧基羰基,氨基羰基,芳烷基,H,低级烷基和环烷基; R5选自低级烷基,芳烷基,环烷基和卤代烷基; R6选自H,低级烷基和芳烷基; R 7和R 8独立地选自H,低级烷基,芳烷基和环烷基。