公开(公告)号：US20090181413A1

公开(公告)日：2009-07-16

申请号：US12088321

申请日：2006-09-29

申请人： Yasuki Itoh ,  Keiko Matsumoto ,  Hiroshi Matsui ,  Yuhko Hirao

发明人： Yasuki Itoh ,  Keiko Matsumoto ,  Hiroshi Matsui ,  Yuhko Hirao

IPC分类号： C12Q1/60 ,  G01N21/00 ,  C12Q1/50 ,  C12Q1/52 ,  C12Q1/32 ,  C12Q1/37 ,  G01N33/92 ,  C12Q1/28

CPC分类号： G01N21/78 ,  C12Q1/60 ,  C12Q1/61 ,  G01N21/272 ,  G01N33/92

摘要： This invention provides a method for differentially and simultaneously quantifying two target analytes via a single assay operation with the use of a single type of reagent in each of the two steps, i.e., the first step and the second step. In this method, the reaction product associated with the first target analyte is detected at an early stage of the second step and the reaction product associated with the second target analyte is then detected.

摘要翻译： 本发明提供了一种用于通过使用单个类型的试剂在两个步骤中的每一个，即第一步骤和第二步骤中通过单一测定操作来差异和同时定量两种目标分析物的方法。 在该方法中，在第二步骤的早期阶段检测与第一目标分析物相关的反应产物，然后检测与第二目标分析物相关的反应产物。

公开(公告)号：US20080297268A1

公开(公告)日：2008-12-04

申请号：US12127201

申请日：2008-05-27

申请人： Hiroshi Matsui ,  Yuichi Takagi

发明人： Hiroshi Matsui ,  Yuichi Takagi

IPC分类号： H03L1/02

CPC分类号： H03L1/025

摘要： A temperature-compensated crystal oscillator includes an oscillation circuit including an oscillator, a temperature detector, a voltage variable capacitance element coupled to an oscillation loop of the oscillation circuit, and a temperature compensation circuit. The temperature compensation circuit is configured to apply a compensation voltage to the voltage variable capacitance element to compensate a temperature change in response to temperature data detected by the temperature detector. The temperature compensation circuit has a plurality of correction point data. The respective correction point data is set in advance for each divided temperature zone, selects a first correction point data in a lower temperature zone and a second correction point data in a higher temperature zone, as compared with the detected temperature data, performs an interpolation between the first and second correction point data by a weighted averaged first-order interpolation, and generates the compensation voltage.

摘要翻译： 温度补偿晶体振荡器包括振荡电路，包括振荡器，温度检测器，耦合到振荡电路的振荡环路的电压可变电容元件和温度补偿电路。 温度补偿电路被配置为向电压可变电容元件施加补偿电压，以补偿由温度检测器检测到的温度数据的温度变化。 温度补偿电路具有多个校正点数据。 对于每个分割的温度区域预先设定各个校正点数据，与检测到的温度数据相比，选择较低温度区域中的第一校正点数据和较高温度区域中的第二校正点数据，执行在 第一和第二校正点数据通过加权平均一阶插值，并产生补偿电压。

公开(公告)号：US20060103764A1

公开(公告)日：2006-05-18

申请号：US11270394

申请日：2005-11-09

申请人： Hiroshi Matsui ,  Masato Onaya

发明人： Hiroshi Matsui ,  Masato Onaya

IPC分类号： H03H7/46 ,  H04N9/77

CPC分类号： H04N9/78 ,  H03H19/004

摘要： A trap filter comprises a delay circuit made up of switched capacitors for delaying an input signal and outputting a delay signal, and an adding circuit for adding the input signal and the delay signal.

摘要翻译： 陷波滤波器包括由用于延迟输入信号并输出​​延迟信号的开关电容器构成的延迟电路，以及用于将输入信号和延迟信号相加的加法电路。

公开(公告)号：US20060078958A1

公开(公告)日：2006-04-13

申请号：US10537992

申请日：2003-12-12

申请人： Hiroshi Matsui

发明人： Hiroshi Matsui

IPC分类号： C12Q1/60

CPC分类号： G01N33/92 ,  G01N2800/044

摘要： The present invention is intended to provide a method for simultaneously measuring cholesterol in low density lipoprotein and total cholesterol as test components in blood. Specifically, a method is used for simultaneously measuring cholesterol in low density lipoprotein and total cholesterol in a biological sample, whereby cholesterol in low density lipoprotein and total cholesterol in a biological sample are quantified with a single measurement.

摘要翻译： 本发明旨在提供一种同时测量低密度脂蛋白胆固醇和总胆固醇作为血液中测试成分的方法。 具体地，使用一种方法同时测量生物样品中低密度脂蛋白和总胆固醇的胆固醇，由此通过单次测量量化生物样品中低密度脂蛋白和总胆固醇的胆固醇。

公开(公告)号：US06479249B2

公开(公告)日：2002-11-12

申请号：US09117806

申请日：1998-08-06

申请人： Hiroshi Matsui ,  Yasuki Ito ,  Shuichi Ohara ,  Akira Fujiwara

发明人： Hiroshi Matsui ,  Yasuki Ito ,  Shuichi Ohara ,  Akira Fujiwara

IPC分类号： C12Q160

CPC分类号： C12Q1/60 ,  Y10S436/824

摘要： Disclosed is a method for quantifying cholesterol in HDL, which does not require complex fragmentation and separation operations, and by which the HDL cholesterol in test samples containing HDL and other lipoproteins such as low density lipoprotein (LDL), very low density lipoprotein (VLDL) and chylomicron (CM) may be quantified selectively, simply and accurately. The method for quantifying cholesterol in high density lipoprotein comprises a first step of erasing cholesterol in lipoproteins other than high density lipoprotein in a test sample, and a second step of adding a surfactant which specifically acts on high density lipoprotein to the product of the first step and enzymatically quantifying cholesterol in high density lipoprotein.

摘要翻译： 本发明公开了一种定量HDL中的胆固醇的方法，其不需要复杂的分离和分离操作，并且含有HDL和其它脂蛋白（例如低密度脂蛋白（LDL），极低密度脂蛋白（VLDL））的测试样品中的HDL胆固醇， 和乳糜微粒（CM）可以选择性，简单和精确地量化。 用于定量高密度脂蛋白中的胆固醇的方法包括在测试样品中除去高密度脂蛋白以外的脂蛋白中的胆固醇的第一步骤，以及将特异性作用于高密度脂蛋白的表面活性剂加入到第一步骤的产物的第二步骤 并在高密度脂蛋白中酶法定量胆固醇。

公开(公告)号：US06414012B1

公开(公告)日：2002-07-02

申请号：US09373163

申请日：1999-08-12

申请人： Hiroshi Matsui ,  Shoji Kamiya ,  Hiroaki Shirahase ,  Shohei Nakamura ,  Katsuo Wada

发明人： Hiroshi Matsui ,  Shoji Kamiya ,  Hiroaki Shirahase ,  Shohei Nakamura ,  Katsuo Wada

IPC分类号： A61P910

CPC分类号： C07D231/12 ,  A61K31/404 ,  A61K31/47 ,  C07D209/08 ,  C07D215/06 ,  C07D215/26 ,  C07D233/56 ,  C07D249/08 ,  C07D401/12 ,  Y10S514/824 ,  Y10S514/866

摘要： Heterocyclic derivatives of the formula (I) wherein each symbol is as defined in the specification, pharmaceutically acceptable salts thereof and method of producing them. Pharmaceutical compositions containing the heterocyclic derivative or a pharmaceutically acceptable salt thereof, particularly, ACAT inhibitors and lipoperoxidation inhibitors. The heterocyclic derivatives and pharmaceutically acceptable salts thereof of the present invention show superior ACAT inhibitory activity and lipoperoxidation inhibitory activity, and are useful as ACAT inhibitors and hyperlipemia inhibitors. To be specific, they are useful for the prevention and treatment of arteriosclerotic lesions of arteriosclerosis, hyperlipemia and diabetes, as well as ischemic diseases of brain, heart and the like.

摘要翻译： 式（I）的杂环衍生物，其中每个符号如说明书中所定义，其药学上可接受的盐及其制备方法。 含有杂环衍生物或其药学上可接受的盐，特别是ACAT抑制剂和脂质过氧化抑制剂的药物组合物。 本发明的杂环衍生物及其药学上可接受的盐显示出优异的ACAT抑制活性和脂质过氧化抑制活性，并且可用作ACAT抑制剂和高脂血症抑制剂。 具体而言，它们可用于预防和治疗动脉硬化，高脂血症和糖尿病的动脉硬化病变，以及脑，心脏等的缺血性疾病。

公开(公告)号：USD457866S1

公开(公告)日：2002-05-28

申请号：US29148914

申请日：2001-10-01

申请人： Hiroshi Matsui ,  Toshio Hotta

设计人： Hiroshi Matsui ,  Toshio Hotta

公开(公告)号：US06396006B1

公开(公告)日：2002-05-28

申请号：US09529158

申请日：2000-06-29

申请人： Shigeru Yokoji ,  Koji Tamano ,  Hiroshi Matsui

发明人： Shigeru Yokoji ,  Koji Tamano ,  Hiroshi Matsui

IPC分类号： H01H2506

CPC分类号： G06F3/0312 ,  G06F3/0338 ,  G06F3/0362 ,  H01H19/11 ,  H01H25/008 ,  H01H25/041 ,  H01H25/06 ,  H01H25/065 ,  H01H2025/048 ,  H01H2217/048 ,  H04M1/0202 ,  H04M1/72519

摘要： A push and rotary operating type electronic device comprises a push switch unit 37 composed in a center of a bottom surface of a case 30, a rotary encoder unit 35 composed at a periphery of the push switch unit, a discoidal operating knob 39 mounted in a manner to be independently movable vertically, while also rotatable conjunctly with the rotary encoder unit 35, wherein the both component units 35 and 37 are operative by depression on a peripheral portion of the operating knob 39 during a rotary manipulation and a center portion of the same in a depressing manipulation. Communication terminal equipment uses this push and rotary operating type electronic device. This structure realizes a small projected area, and allows the rotary manipulation and the depressing manipulation by operating different portions of the single operating knob 39.

摘要翻译： 推动和旋转操作型电子设备包括构成在壳体30的底面的中心的按钮开关单元37，组成在按钮开关单元周围的旋转编码器单元35，安装在 方式可独立地垂直移动，同时也可与旋转编码器单元35一起旋转，其中两个部件单元35和37通过在旋转操纵期间的操作旋钮39的周边部分上的凹陷和相同的中心部分 在一个令人沮丧的操纵。 通讯终端设备采用这种推，旋式操作型电子设备。 这种结构实现了小的投影面积，并且通过操作单个操作旋钮39的不同部分来允许旋转操纵和按压操作。

公开(公告)号：US06333473B1

公开(公告)日：2001-12-25

申请号：US09469788

申请日：1999-12-22

申请人： Masaki Sawada ,  Hiroto Inoue ,  Hiroshi Matsui

发明人： Masaki Sawada ,  Hiroto Inoue ,  Hiroshi Matsui

IPC分类号： A01H2500

CPC分类号： H01H25/008 ,  G05G9/047 ,  H01H2019/146

摘要： A rotary-push type electronic component is provided for use in an electronic appliance such as a mobile phone. The electronic component includes a base unit, a frame mounted to the base unit, a support shaft coupling the frame to the base unit for pivotal and vertical movement of the frame relative to the base unit, a generally cylindrical operation knob rotatably mounted to the frame, a rotary operation device for emitting an electric signal upon rotation of the generally cylindrical operation knob, and a pair of self-restoring push operation parts spaced apart on the base unit below the frame so as to be operated by pivoting of the frame about the support shaft relative to the base unit. The support shaft is disposed at a rear portion of the frame, and the push operation parts are disposed beneath a front portion of the frame.

摘要翻译： 提供用于诸如移动电话的电子设备中的旋转式电子部件。 电子部件包括基座单元，安装到基座单元的框架，将框架联接到基座单元的支撑轴，用于框架相对于基座单元的枢转​​和垂直运动;大致圆柱形的操作旋钮，可旋转地安装到框架 旋转操作装置，用于在大体上圆柱形的操作旋钮旋转时发出电信号;以及一对自恢复推动操作部件，其间隔地设置在框架下方的基座部件上， 支撑轴相对于基座单元。 支撑轴设置在框架的后部，并且推动操作部分设置在框架的前部下方。

公开(公告)号：US06200988B1

公开(公告)日：2001-03-13

申请号：US09506839

申请日：2000-02-18

申请人： Shoji Kamiya ,  Hiroaki Shirahase ,  Hiroshi Matsui ,  Shohei Nakamura ,  Katsuo Wada

发明人： Shoji Kamiya ,  Hiroaki Shirahase ,  Hiroshi Matsui ,  Shohei Nakamura ,  Katsuo Wada

IPC分类号： C07D21540

CPC分类号： C07D209/08

摘要： A heterocyclic derivative of the formula (I) wherein each symbol is as defined in the specification, and pharmaceutically acceptable salts thereof. The compound (I) of the present invention and pharmaceutically acceptable salts thereof exhibit superior ACAT inhibitory activity and lipoperoxidation inhibitory activity in mammals, and are useful as ACAT inhibitors and lipoperoxidation inhibitors. Specifically, they are useful for the prophylaxis and treatment of arteriosclerosis, hyperlipemia, arteriosclerosis in diabetes, and cerebrovascular and cardiovascular ischemic diseases.

摘要翻译： 式（I）的杂环衍生物，其中每个符号如说明书中所定义，及其药学上可接受的盐。 本发明的化合物（I）及其药学上可接受的盐在哺乳动物中表现出优异的ACAT抑制活性和脂过氧化抑制活性，可用作ACAT抑制剂和脂质过氧化抑制剂。 具体地说，它们可用于预防和治疗动脉硬化，高脂血症，糖尿病中的动脉硬化，以及脑血管和心血管缺血性疾病。