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    VALVED CARTRIDGE AND SYSTEM
    13.
    发明申请
    VALVED CARTRIDGE AND SYSTEM 审中-公开
    阀门和系统

    公开(公告)号：US20160367981A1

    公开(公告)日：2016-12-22

    申请号：US15173894

    申请日：2016-06-06

    Applicant: IntegenX Inc.

    Inventor： Philip Justus Wunderle ,  Chungsoo Charles Park ,  David King ,  Dennis Lehto

    IPC: B01L3/00 ,  C12Q1/68

    CPC classification number: C12Q1/6874 ,  B01F13/0059 ,  B01F13/02 ,  B01L3/502738 ,  B01L3/502753 ,  B01L7/52 ,  B01L2200/04 ,  B01L2200/0668 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2300/123 ,  B01L2400/043 ,  B01L2400/0478 ,  B01L2400/0655 ,  C12Q1/686 ,  F16K99/0015 ,  F16K99/0034 ,  F16K2099/0078 ,  F16K2099/0084

    Abstract: This disclosure provides, among other things, a cartridge comprising: (a) a cartridge body comprising a malleable material and having, disposed on a surface of the body, at least one valve body comprising a valve inlet and a valve outlet, each fluidically connected to a fluidic channel; and (b) a layer comprising a deformable material bonded to a surface of the cartridge body and sealing the at least one valve body at points of attachment, thereby forming at least one valve; wherein the at least one valve body is depressed in the cartridge body relative to the points of attachment and wherein the deformable material covering the at least one valve body retains sufficient elasticity after deformation such that in a ground state the valve is open. Also disclosed is an instrument comprising a cartridge interface and a cartridge as described herein engaged with the cartridge interface, wherein (II) the cartridge interface comprises: (A) at least one mechanical actuator, each mechanical actuator positioned to actuate a valve; and (B) at least one motor operatively coupled to actuate a mechanical actuator toward or away from a valve.

    Abstract translation: 本公开尤其提供了一种盒，其包括：（a）包括可延展材料的盒体，并且具有设置在主体表面上的至少一个阀体，其包括阀入口和阀出口，每个阀体流体连接 到流体通道; 和（b）包含结合到所述盒体表面的可变形材料并且在附接点处密封所述至少一个阀体从而形成至少一个阀的层; 其中所述至少一个阀体相对于所述连接点在所述盒体中被压下，并且其中覆盖所述至少一个阀体的所述可变形材料在变形之后保持足够的弹性，使得在基础状态下所述阀是打开的。 还公开了一种包括如本文所述的盒接口和与盒接口接合的盒的仪器，其中（II）盒接口包括：（A）至少一个机械致动器，每个机械致动器被定位成致动阀; 和（B）至少一个电动机，其可操作地联接以朝向或远离阀致动机械致动器。

    Valved cartridge and system
    15.
    发明授权
    Valved cartridge and system 有权

    公开(公告)号：US10233491B2

    公开(公告)日：2019-03-19

    申请号：US15173894

    申请日：2016-06-06

    Applicant: IntegenX Inc.

    Inventor： Philip Justus Wunderle ,  Chungsoo Charles Park ,  David King ,  Dennis Lehto

    IPC: C12Q1/6874 ,  C12Q1/686 ,  B01L3/00 ,  F16K99/00 ,  B01L7/00 ,  B01F13/00 ,  B01F13/02

    Abstract: This disclosure provides, among other things, a cartridge comprising: (a) a cartridge body comprising a malleable material and having, disposed on a surface of the body, at least one valve body comprising a valve inlet and a valve outlet, each fluidically connected to a fluidic channel; and (b) a layer comprising a deformable material bonded to a surface of the cartridge body and sealing the at least one valve body at points of attachment, thereby forming at least one valve; wherein the at least one valve body is depressed in the cartridge body relative to the points of attachment and wherein the deformable material covering the at least one valve body retains sufficient elasticity after deformation such that in a ground state the valve is open. Also disclosed is an instrument comprising a cartridge interface and a cartridge as described herein engaged with the cartridge interface, wherein (II) the cartridge interface comprises: (A) at least one mechanical actuator, each mechanical actuator positioned to actuate a valve; and (B) at least one motor operatively coupled to actuate a mechanical actuator toward or away from a valve.

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