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公开(公告)号:US20220203358A1
公开(公告)日:2022-06-30
申请号:US17138024
申请日:2020-12-30
Applicant: International Business Machines Corporation
Inventor: Ricardo Luis Ohta , Jaione Tirapu Azpiroz , Matheus Esteves Ferreira , Daniel Vitor Lopes Marcondes Marçal , Ademir Ferreira da Silva , Mathias B. Steiner
Abstract: Devices and methods for controlling collection of liquid sample are described. In an example, a microfluidic device can include an analytical device and an actuator. The actuator can be connected to the analytical device. The actuator can be operable to absorb fluid. The actuator can guide the absorbed fluid to an input layer of the analytical device. The actuator can deform in response to an occurrence of an absorption condition. A degree of deformation of the actuator indicates a volume of fluid collected by the analytical device.
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公开(公告)号:US20220062897A1
公开(公告)日:2022-03-03
申请号:US17008611
申请日:2020-08-31
Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
Inventor: Ademir Ferreira da Silva , Daniel Vitor Lopes Marcondes Marçal , Jaione Tirapu Azpiroz , Matheus Esteves Ferreira , Mathias B. Steiner , Ricardo Luis Ohta
Abstract: A rapid test device includes a micropad chip configured for a multi-parameter chemical testing of an input sample. A plurality of paper layers of the micropad chip are in fluid communication, including a sample absorption element, a filtering element configured to filter the input sample, and a sample distribution element configured to distribute the input sample received from the filtering element to a remainder of the plurality of paper layers. One or more reacting elements associated with the multi-parameter chemical testing of the input sample have one or more colorimetric reagents in fluid communication with the sample distribution element. A colorimetric result displaying element in fluid communication with the one or more reacting elements is configured to display a colorimetric result of the testing of the input sample with the at least one reacting element for a respective chemical test of the multi-parameter chemical testing.
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公开(公告)号:US20210374646A1
公开(公告)日:2021-12-02
申请号:US16887607
申请日:2020-05-29
Applicant: International Business Machines Corporation
Inventor: Paulo Rodrigo Cavalin , Carmen Nilda Mena Paz , Jaione Tirapu Azpiroz , Ana Paula Appel , Alexandre Alves
Abstract: A product quality analysis and control system is provided. The product quality analysis and control system includes a processing system that is configured to receive data of objective qualities of a product from multiple data gathering modules. Each of the multiple data gathering modules is respectively positioned at corresponding nodes of a supply chain and is configured to receive from sensors data of objective qualities of a product when the product is at each of the corresponding nodes. The processing system includes a model repository and a data evaluation module. The data evaluation module is configured to select, from the model repository, a model associated with a type of the product and to use the model to analyze the data to identify changes in the objective qualities along the supply chain.
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公开(公告)号:US20200378957A1
公开(公告)日:2020-12-03
申请号:US16428961
申请日:2019-05-31
Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
Inventor: Jaione Tirapu Azpiroz , Ademir Ferreira da Silva , Matheus Esteves Ferreira , Ricardo Luis Ohta , Mathias B. Steiner , Nara Mazarakis Rubim , Pedro Paulo Ferreira Ribeiro , Edimilson Domingos da Silva , Antonio Gomez Pinto Ferreira
IPC: G01N33/536 , G01N33/53
Abstract: A multiplexed lateral flow assay device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir and divides a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable paper top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays. The housing element includes an impermeable bottom cover and a spacer element arranged between the top and bottom covers and, provides a gap between the lateral flow assays and the impermeable paper top cover.
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公开(公告)号:US10816456B2
公开(公告)日:2020-10-27
申请号:US15297742
申请日:2016-10-19
Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
Abstract: A reconfigurable point-of-care system, comprising an analysis device having one or more detection components to perform a diagnostic method on a sample, the sample being loaded on a microfluidic chip, wherein the analysis device provides identification information, an interface device coupled to the analysis device to provide a communication channel, and a reader unit coupled to the communication channel and having a processor to select the diagnostic method based on the identification information and reconfigure one or more components of the interface device based on the analysis device.
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公开(公告)号:US10679849B2
公开(公告)日:2020-06-09
申请号:US16539071
申请日:2019-08-13
Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
Inventor: Michael Engel , Mathias B. Steiner , Jaione Tirapu Azpiroz
Abstract: A method of positioning nanomaterials includes patterning guiding dielectric features from a single layer of guiding dielectric material, and producing an electric field by at least one electrode disposed on a substrate that is attenuated through the guiding dielectric features to create an attractive dielectrophoretic force that guides at least one nanostructure abutting the guiding dielectric features to be positioned on a deposition surface of the substrate.
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公开(公告)号:US10431453B2
公开(公告)日:2019-10-01
申请号:US15362191
申请日:2016-11-28
Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
Inventor: Michael Engel , Mathias B. Steiner , Jaione Tirapu Azpiroz
Abstract: A method of positioning nanomaterials that includes forming a set of electrodes on a substrate, and covering the electrodes and substrate with a single layer of guiding dielectric material. The method may continue with patterning the guiding dielectric to provide dielectric guide features, wherein an exposed portion of the substrate between the dielectric guide features provides a deposition surface. A liquid medium containing at least one nanostructure is applied to the guiding dielectric features and the deposition surface. An electric field produced by the electrodes that is attenuated by the dielectric guide features creates an attractive force that guides the nanostructures to the deposition surface.
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公开(公告)号:US10429303B2
公开(公告)日:2019-10-01
申请号:US15469007
申请日:2017-03-24
Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
Inventor: Michael Engel , Jeannette M. Garcia , Ricardo L. Ohta , Ademir F. Silva , Mathias B. Steiner , Jaione Tirapu Azpiroz , Thomas G. Zimmerman
Abstract: A portable optical measurement system is provided for performing metal trace analysis on a liquid sample. The system includes a sample holder for holding an analysis substrate that includes the liquid sample during the metal trace analysis. The system further includes an ultraviolet (UV) light source for emitting ultraviolet light illuminating the liquid sample. The system also includes an optical sensor for detecting radiation emanating from the liquid sample and converting the detected radiation into an electrical signal. The system additionally includes a microcontroller for processing the electrical signal. The system further includes an external interface for transmitting the processed electrical signal to an external device.
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公开(公告)号:US10343162B2
公开(公告)日:2019-07-09
申请号:US15977046
申请日:2018-05-11
Applicant: International Business Machines Corporation
Inventor: Jaione Tirapu Azpiroz , Peter William Bryant , Rodrigo Neumann Barros Ferreira , Ronaldo Giro , Ricardo Luis Ohta
Abstract: A microfluidic device, including a matrix array of controllable shape-changing micropillars where a shape of the shape-changing micropillars is changed by a fluid.
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公开(公告)号:US11648562B2
公开(公告)日:2023-05-16
申请号:US16671284
申请日:2019-11-01
Applicant: International Business Machines Corporation
Inventor: Ricardo L. Ohta , Jaione Tirapu Azpiroz , Ademir F. Silva , Matheus Esteves Ferreira , Mathias B. Steiner
CPC classification number: B01L3/508 , G16H10/40 , G16H10/60 , B01L2300/021 , B01L2300/0816 , G16H10/65
Abstract: Method, apparatus, and computer program product are provided for anonymized diagnosis using lateral flow assays. In some embodiments, a test card includes one or more lateral flow assay (LFA) with one or more test patterns (e.g., full line, partial line, dot), one or more dummy patterns, and one or more control patterns. To visually encode LFA results, at manufacture, one or more lines/dots containing true results of the LFA(s) each has a position mixed with other “dummy” lines/dots, in randomized position patterns selected from among a plurality of possible position patterns. An optical machine-readable representation of data (e.g., QR code) is attached to the test card and encodes test card identification information (e.g., lot number, serial number, test type) associated with the test card. In some embodiments, a passcode card having a scrapeable coating that conceals a passcode associated with the test card is removably attached to the test card.
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