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公开(公告)号：US20200378957A1
公开(公告)日：2020-12-03
申请号：US16428961
申请日：2019-05-31
发明人： Jaione Tirapu Azpiroz , Ademir Ferreira da Silva , Matheus Esteves Ferreira , Ricardo Luis Ohta , Mathias B. Steiner , Nara Mazarakis Rubim , Pedro Paulo Ferreira Ribeiro , Edimilson Domingos da Silva , Antonio Gomez Pinto Ferreira
IPC分类号： G01N33/536 , G01N33/53
摘要： A multiplexed lateral flow assay device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir and divides a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable paper top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays. The housing element includes an impermeable bottom cover and a spacer element arranged between the top and bottom covers and, provides a gap between the lateral flow assays and the impermeable paper top cover.
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公开(公告)号：US11549943B2
公开(公告)日：2023-01-10
申请号：US16428961
申请日：2019-05-31
发明人： Jaione Tirapu Azpiroz , Ademir Ferreira da Silva , Matheus Esteves Ferreira , Ricardo Luis Ohta , Mathias B. Steiner , Nara Mazarakis Rubim , Pedro Paulo Ferreira Ribeiro , Edimilson Domingos da Silva , Antonio Gomez Pinto Ferreira
IPC分类号： G01N33/543 , G01N33/53 , G01N33/536
摘要： A multiplexed lateral flow assay device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir and divides a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable paper top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays. The housing element includes an impermeable bottom cover and a spacer element arranged between the top and bottom covers and, provides a gap between the lateral flow assays and the impermeable paper top cover.
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公开(公告)号：US11906515B2
公开(公告)日：2024-02-20
申请号：US16845035
申请日：2020-04-09
发明人： Jaione Tirapu Azpiroz , Ademir Ferreira da Silva , Matheus Esteves Ferreira , Ricardo Luis Ohta , Mathias B. Steiner , Antonio Gomes Pinto Ferreira , Edimilson Domingos da Silva , Nara Mazarakis Rubim , Pedro Paulo Ferreira Ribeiro
IPC分类号： G01N33/543 , B01L3/00 , G01N33/571
CPC分类号： G01N33/54389 , B01L3/50273 , B01L3/502715 , G01N33/571 , B01L2200/10 , B01L2300/0816 , B01L2300/0867 , B01L2400/0487
摘要： A multiplexed lateral flow device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir. The fluid distributor pad includes a paper based microfluidic element having a pattern of a hydrophobic material to distribute a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays. The housing element includes an impermeable bottom cover and a spacer element arranged between the top and bottom covers and, provides a gap between the lateral flow assays and the impermeable top cover.
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公开(公告)号：US20200376485A1
公开(公告)日：2020-12-03
申请号：US16845035
申请日：2020-04-09
发明人： Jaione Tirapu Azpiroz , Ademir Ferreira da Silva , Matheus Esteves Ferreira , Ricardo Luis Ohta , Mathias B. Steiner , Antonio Gomes Pinto Ferreira , Edimilson Domingos da Silva , Nara Mazarakis Rubim , Pedro Paulo Ferreira Ribeiro
IPC分类号： B01L3/00 , G01N33/571
摘要： A multiplexed lateral flow device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir. The fluid distributor pad includes a paper based microfluidic element having a pattern of a hydrophobic material to distribute a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays. The housing element includes an impermeable bottom cover and a spacer element arranged between the top and bottom covers and, provides a gap between the lateral flow assays and the impermeable top cover.
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