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公开(公告)号:US11986168B2
公开(公告)日:2024-05-21
申请号:US17103912
申请日:2020-11-24
Applicant: InnovaPrep LLC
Inventor: Alec D. Adolphson , Ann K. Packingham , Andrew E. Page , David S. Alburty , Zachary A. Packingham , John D. Birkenholz , Michael F. Fischer
CPC classification number: A61B10/02 , A61B10/0096 , A61B2010/0216 , B01L3/5029 , G01N2001/028
Abstract: Devices, systems and methods are disclosed which relate to using wet foam elution for removal of particles from swabs and wipes. This allow users to capture particles from surfaces and recover them by elution into small sample volumes for subsequent detection for human clinical, veterinary, food safety, pharmaceutical, outbreak investigations, forensics, biodefense and bioterrorism response, environmental monitoring, and other applications where collection of samples from surfaces and humans or animals is required. More specifically, the swabs or wipes are used to collect samples in the standard ways that commercially available swabs and wipes are in use today; from, for instance, food preparation surfaces in food plants, from production equipment in pharmaceutical facilities, for collection of dry powders during bioterrorism event response, and for collection of clinical samples such as nasal, throat, nasopharyngeal, and wounds.
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公开(公告)号:US20220341826A1
公开(公告)日:2022-10-27
申请号:US17726625
申请日:2022-04-22
Applicant: INNOVAPREP LLC
Inventor: Alec D. Adolphson , Andrew E. Page , John D. Birkenholz , David Goad
Abstract: Devices, systems and methods are disclosed which relate to a prefiltration device that can be used with the concentrating pipette instruments and other devices which draw a sample in through one opening and dispense a concentrated or eluted sample out through the same opening. The device allows the sample to be passed through a prefilter when entering the opening and then bypassed the prefilter when being dispensed through the same opening.
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公开(公告)号:US20200224242A1
公开(公告)日:2020-07-16
申请号:US16775034
申请日:2020-01-28
Applicant: InnovaPrep LLC
Inventor: David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
Abstract: A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
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公开(公告)号:US09738918B2
公开(公告)日:2017-08-22
申请号:US14313618
申请日:2014-06-24
Applicant: InnovaPrep LLC
Inventor: David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
CPC classification number: C12Q1/24 , C12Q1/04 , G01N1/4005 , G01N1/4077 , G01N2001/4088
Abstract: A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
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公开(公告)号:US20140308659A1
公开(公告)日:2014-10-16
申请号:US14313618
申请日:2014-06-24
Applicant: InnovaPrep LLC
Inventor: David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
CPC classification number: C12Q1/24 , C12Q1/04 , G01N1/4005 , G01N1/4077 , G01N2001/4088
Abstract: A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
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