公开(公告)号：US11149260B2

公开(公告)日：2021-10-19

申请号：US17319022

申请日：2021-05-12

Applicant: Inscripta, Inc.

Inventor： Skylar Stefani ,  Tian Tian ,  Miles Gander

IPC: C12N9/22 ,  C12N15/85 ,  C12Q1/44

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US11034945B2

公开(公告)日：2021-06-15

申请号：US17039436

申请日：2020-09-30

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Skylar Stefani

IPC: C12N9/22 ,  C12N15/85 ,  C12Q1/44

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US11001831B2

公开(公告)日：2021-05-11

申请号：US17061143

申请日：2020-10-01

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Skylar Stefani

IPC: C12N15/10

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US20230012154A1

公开(公告)日：2023-01-12

申请号：US17679203

申请日：2022-02-24

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Skylar Stefani ,  Patrick Westfall

IPC: C12N15/10

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US20220389461A1

公开(公告)日：2022-12-08

申请号：US17752122

申请日：2022-05-24

Applicant: Inscripta, Inc.

Inventor： Randy Lacey ,  Bryan Leland ,  Eileen Spindler ,  Patrick Westfall ,  Skylar Stefani ,  Catherine Baranowski

IPC: C12N15/90 ,  G16B20/20

Abstract: The present disclosure relates to automated multi-module instruments, compositions and methods for performing nucleic acid-guided nuclease editing; specifically, methods, instruments, systems, and nucleic acids synthetic cassettes that improve the efficiency of gene editing using CRISPR enzymes in diploid cells—either on both chromosomes or selectively in one chromosome—without incurring loss of heterozygosity (LOH) and its often deleterious effects.

公开(公告)号：US20220195409A1

公开(公告)日：2022-06-23

申请号：US17692108

申请日：2022-03-10

Applicant: Inscripta, Inc.

Inventor： Skylar Stefani ,  Tian Tian ,  Miles Gander

IPC: C12N9/22 ,  C12N15/113

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US20210395727A1

公开(公告)日：2021-12-23

申请号：US17463956

申请日：2021-09-01

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Skylar Stefani ,  Patrick Westfall

IPC: C12N15/10

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US20210269784A1

公开(公告)日：2021-09-02

申请号：US17319022

申请日：2021-05-12

Applicant: Inscripta, Inc.

Inventor： Skylar Stefani ,  Tian Tian ,  Miles Gander

IPC: C12N9/22 ,  C12N15/85 ,  C12Q1/44

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US10815467B2

公开(公告)日：2020-10-27

申请号：US16827639

申请日：2020-03-23

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Skylar Stefani

IPC: C12N9/22 ,  C12N15/85 ,  C12Q1/44

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US20200308562A1

公开(公告)日：2020-10-01

申请号：US16827639

申请日：2020-03-23

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Skylar Stefani

IPC: C12N9/22 ,  C12Q1/44 ,  C12N15/85

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.