公开(公告)号：US11241532B2

公开(公告)日：2022-02-08

申请号：US16116071

申请日：2018-08-29

Applicant: Insulet Corporation

Inventor： David Nazzaro ,  John D'Arco ,  Jason O'Connor ,  Ian McLaughlin

IPC: A61M5/168 ,  A61B5/145 ,  A61M5/142 ,  A61M5/172 ,  A61B5/00

Abstract: A drug delivery system having a drug delivery device and an associated sensor is provided. The sensor can be associated with a sensing site on user. The drug delivery device can be positioned over the sensor in any rotational position and can be associated with an infusion site on the user. The close positioning of the sensor and the drug delivery device allows data from the sensor to be relayed to the drug delivery device and then on to a remote control device. Further, the drug delivery device can be replaced at the end of its duration of use, which is shorter than the duration of use of the sensor, without disturbing the sensor. Subsequent drug delivery devices can then be used with the sensor while allowing each corresponding infusion site to be changed, thereby providing more efficient operation of the drug delivery system.

公开(公告)号：US11040139B2

公开(公告)日：2021-06-22

申请号：US16781146

申请日：2020-02-04

Applicant: Insulet Corporation

Inventor： Ian McLaughlin

IPC: A61M5/00 ,  A61M5/168 ,  A61M5/24 ,  A61L2/00 ,  A61L2/08 ,  A61M5/162 ,  A61M5/31 ,  A61M5/32 ,  A61M39/10 ,  A61L2/07 ,  A61L2/20 ,  A61M5/145 ,  A61M5/19

Abstract: The present disclosure relates generally to the field of drug delivery. In particular, the present disclosure relates to a drug delivery system that includes a sealed and sterile fluid path attached to a drug-loaded container. The disclosure further relates to methods for sterilizing a portion of the drug delivery system without exposing the drug-loaded container to harmful sterilization parameters.

公开(公告)号：US20190255251A1

公开(公告)日：2019-08-22

申请号：US16194873

申请日：2018-11-19

Applicant: Insulet Corporation

Inventor： Steven DiIanni ,  Ian McLaughlin ,  Jason Brian O'Connor ,  Robert Campbell ,  Kevin Schmid

IPC: A61M5/145 ,  A61M5/172 ,  A61M5/142 ,  F04B9/02 ,  A61M5/158 ,  A61B5/1486 ,  A61B5/145

Abstract: A fluid delivery device comprising a fluid reservoir; a transcutaneous access tool fluidly coupled to the fluid reservoir, the transcutaneous access tool including a needle or a trocar; and a transcutaneous access tool insertion mechanism for deploying the transcutaneous access tool, wherein the insertion mechanism is configured to insert and retract the needle/trocar in a single, uninterrupted motion.

公开(公告)号：US20170340827A1

公开(公告)日：2017-11-30

申请号：US15607169

申请日：2017-05-26

Applicant: Insulet Corporation

Inventor： David Nazzaro ,  Ian McLaughlin ,  Simon Kozin ,  Maureen McCaffrey ,  Jackie Mac ,  Alexander Doudoumopoulus ,  Bhavin Patel

IPC: A61M5/315 ,  A61M5/28 ,  A61M5/31 ,  A61M37/00

CPC classification number: A61M5/31593 ,  A61M5/14248 ,  A61M5/28 ,  A61M5/31531 ,  A61M5/32 ,  A61M5/42 ,  A61M37/00 ,  A61M2005/2474 ,  A61M2005/3142 ,  A61M2005/31518

Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can be controlled to provide the liquid drug to the patient in a single dose or over multiple doses.

公开(公告)号：US12128215B2

公开(公告)日：2024-10-29

申请号：US17487570

申请日：2021-09-28

Applicant: Insulet Corporation

Inventor： Steven Cardinali ,  David Nazzaro ,  Ian McLaughlin

IPC: A61M5/172

CPC classification number: A61M5/1723 ,  A61M2205/0238 ,  A61M2205/3313 ,  A61M2230/201

Abstract: Embodiments of the present disclosure relate to approaches for more efficiently measuring glucose levels using a wearable drug delivery device. In some embodiments, the wearable drug delivery device may include a needle deployment component including a cannula and an optical conduit deployable into a user, the cannula operable to deliver a liquid drug to the user. The wearable drug delivery device may further include a glucose monitor including an optical sensor, the optical sensor operable to measure a light output received via the optical conduit.

公开(公告)号：US11280327B2

公开(公告)日：2022-03-22

申请号：US16054323

申请日：2018-08-03

Applicant: Insulet Corporation

Inventor： Daniel Allis ,  Ian McLaughlin ,  Kenneth Phillips

IPC: F04B19/00 ,  F04B1/02 ,  F04B53/10 ,  F04B1/047 ,  F04B1/0452 ,  F04B7/00 ,  F04B9/06 ,  F04B19/22 ,  F04B23/02

Abstract: A low-force, non-displacement, micro/miniature valve and/or pump assembly is provided. A tube component having a first side port coupled to an inlet portion and a second side port coupled to an outlet portion can be selectively moved to alternatively couple the side ports to a first or second piston pump chamber. First and second pistons can be actuated after positioning the tube component to either draw in fluid or push out fluid from either the first or second piston pump chambers during each actuation of the pistons. The fluid can be drawn in from a reservoir and can be expelled to a patient for providing a dose of the fluid to the patient.

公开(公告)号：US11229741B2

公开(公告)日：2022-01-25

申请号：US16552492

申请日：2019-08-27

Applicant: Insulet Corporation

Inventor： Steven Diianni ,  Ian McLaughlin ,  Jason Brian O'Connor ,  Robert Campbell ,  Kevin Schmid

IPC: A61M5/145 ,  A61B5/145 ,  A61B5/1486 ,  A61M5/142 ,  F04B9/02 ,  A61M5/172 ,  A61M5/158 ,  A61M5/32 ,  A61M5/14

Abstract: A fluid delivery device comprising a fluid reservoir; a transcutaneous access tool fluidly coupled to the fluid reservoir; and a drive mechanism for driving fluid from the reservoir, the drive mechanism comprising a plunger received in the reservoir; a leadscrew extending from the plunger; a nut threadably engaged with the leadscrew; a drive wheel; and a clutch mechanism coupled to the drive wheel, wherein the clutch mechanism is configured to allow the nut to pass through when disengaged and is configured to grip the nut when engaged such that the drive wheel rotates the nut to advance the drive rod and the plunger into the reservoir.

公开(公告)号：US11129943B2

公开(公告)日：2021-09-28

申请号：US15980469

申请日：2018-05-15

Applicant: Insulet Corporation

Inventor： David Nazzaro ,  Ian McLaughlin ,  Simon Kozin ,  Maureen McCaffrey ,  Jackie Mac ,  Alexander Doudoumopoulos ,  Bhavin Patel

IPC: A61M5/315 ,  A61M5/142 ,  A61M5/28 ,  A61M5/32 ,  A61M5/24 ,  A61M37/00 ,  A61M5/31 ,  A61M5/42

Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can be controlled to provide the liquid drug to the patient in a single dose or over multiple doses.

公开(公告)号：US10973939B2

公开(公告)日：2021-04-13

申请号：US16053231

申请日：2018-08-02

Applicant: Insulet Corporation

Inventor： Ian McLaughlin

IPC: B65B3/00 ,  B65B55/04 ,  B65B55/10 ,  A61L2/20 ,  A61M39/18 ,  A61M5/142 ,  A61M5/28 ,  A61L2/08 ,  A61L2/26 ,  A61M5/00

Abstract: A method for sterilizing a drug delivery device may comprise disposing a liquid drug container, a needle conduit and a cap in a sterilization enclosure so that a mouth portion of the liquid drug container is registered with, and spaced apart from, a circumferential lip of the cap; disposing a cover over the liquid drug container, the needle conduit, and the cap, sealing the sterilization enclosure; subjecting the interior of the sterilization enclosure to a sterilization process in which the liquid drug container, the needle conduit, and the cap are exposed to the sterilization fluid and are sterilized; and applying a downward force to the liquid drug container to move the mouth portion into engagement with the circumferential lip of the cap and to snap the cap onto the liquid drug container to seal the cap and needle conduit to the liquid drug container in an assembled configuration.

公开(公告)号：US10342926B2

公开(公告)日：2019-07-09

申请号：US15607169

申请日：2017-05-26

Applicant: Insulet Corporation

Inventor： David Nazzaro ,  Ian McLaughlin ,  Simon Kozin ,  Maureen McCaffrey ,  Jackie Mac ,  Alexander Doudoumopoulos ,  Bhavin Patel

IPC: A61M5/24 ,  A61M5/28 ,  A61M5/31 ,  A61M5/32 ,  A61M5/42 ,  A61M37/00 ,  A61M5/142 ,  A61M5/315

Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can be controlled to provide the liquid drug to the patient in a single dose or over multiple doses.