公开(公告)号：US11633541B2

公开(公告)日：2023-04-25

申请号：US16794689

申请日：2020-02-19

Applicant: Insulet Corporation

Inventor： Maureen McCaffrey ,  David Nazzaro ,  Ian McLaughlin ,  Simon Kozin

IPC: A61M37/00 ,  A61M5/28 ,  A61M5/24 ,  A61M5/34 ,  A61M5/32 ,  A61M5/315 ,  A61M5/142 ,  A61J1/20

Abstract: Drug delivery systems with reduced hold-up volumes are provided. The drug delivery systems include a cartridge configured to hold a liquid drug. A cartridge stopper is positioned in a first portion of the cartridge. A needle guide component is positioned within the cartridge stopper. A needle is positioned within a central opening of the needle guide. A plunger is positioned in a second portion of the cartridge. The plunger includes a fluid path pocket facing and aligned with the central opening of the needle guide component. The plunger is driven toward the cartridge stopper to expel the liquid drug from the cartridge through the needle. An end of the needle can be positioned within the fluid path pocket when the plunger is pushed against the cartridge stopper, ensuring that only a small volume of the liquid drug remains in the cartridge when delivery of the liquid drug is completed.

公开(公告)号：US10589025B2

公开(公告)日：2020-03-17

申请号：US16279996

申请日：2019-02-19

Applicant: Insulet Corporation

Inventor： Ian McLaughlin

IPC: A61M5/19 ,  A61M5/168 ,  A61M5/24 ,  A61L2/00 ,  A61L2/08 ,  A61M5/162 ,  A61M5/31 ,  A61M5/32 ,  A61M39/10 ,  A61L2/07 ,  A61L2/20 ,  A61M5/00 ,  A61M5/145

Abstract: The present disclosure relates generally to the field of drug delivery. In particular, the present disclosure relates to a drug delivery system that includes a sealed and sterile fluid path attached to a drug-loaded container. The disclosure further relates to methods for sterilizing a portion of the drug delivery system without exposing the drug-loaded container to harmful sterilization parameters.

公开(公告)号：US10130758B2

公开(公告)日：2018-11-20

申请号：US13854445

申请日：2013-04-01

Applicant: Insulet Corporation

Inventor： Steven DiIanni ,  Ian McLaughlin ,  Jason Brian O'Connor ,  Robert Campbell ,  Kevin Schmid

IPC: A61M5/20 ,  A61M5/145 ,  A61B5/145 ,  A61B5/1486 ,  F04B9/02 ,  A61M5/142 ,  A61M5/172 ,  A61M5/158 ,  A61M5/32 ,  A61M5/14

Abstract: A fluid delivery device comprising a fluid reservoir; a transcutaneous access tool fluidly coupled to the fluid reservoir, the transcutaneous access tool including a needle or a trocar; and a transcutaneous access tool insertion mechanism for deploying the transcutaneous access tool, wherein the insertion mechanism is configured to insert and retract the needle/trocar in a single, uninterrupted motion.

公开(公告)号：US20170189270A1

公开(公告)日：2017-07-06

申请号：US15398657

申请日：2017-01-04

Applicant: INSULET CORPORATION

Inventor： David Nazzaro ,  Maureen McCaffrey ,  Robert F. Rioux ,  Michael Philip Graffeo ,  Ian McLaughlin ,  Nicholas Jansky ,  Sam Rosenblum ,  David Clare ,  Robert D. Schaefer ,  Daniel P. Allis ,  Bryan Dillon ,  Steven Barletta ,  Bryan Choate ,  Raymond Dobry ,  John LeFavour

IPC: A61J1/20 ,  A61J1/14

CPC classification number: A61M5/1782 ,  A61M5/321 ,  A61M2005/3109 ,  A61M2005/3267 ,  A61M2205/6045

Abstract: Systems, components, and methods are disclosed for withdrawing drug from a liquid drug container and transferring drug to a medical device. One or more components may have keying features so that only the correct liquid drug container and medical device are accessed, making sure the medical device is filled with the correct drug. A syringe needle hub may have keying features corresponding to keying features on a cap on the liquid drug container and on the medical device. An alignment device facilitates easy-to-operate filling of a medical device. The alignment device aligns a liquid drug container over a fill port of the medical device and can include components for moving the liquid drug container into engagement with the medical device and for automatically initiating drug transfer to the medical device. A retractable skirt or needle cover protects the needle and is unlocked only when the skirt or needle cover is close to or touching the medical device.

公开(公告)号：US20140142508A1

公开(公告)日：2014-05-22

申请号：US13854445

申请日：2013-04-01

Applicant: Insulet Corporation

Inventor： Steven DiIanni ,  Ian McLaughlin ,  Jason Brian O'Connor ,  Robert Campbell ,  Kevin Schmid

IPC: A61M5/158 ,  A61M5/142

CPC classification number: A61M5/14566 ,  A61B5/14532 ,  A61B5/14865 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/1452 ,  A61M5/158 ,  A61M5/1723 ,  A61M5/3291 ,  A61M2005/1403 ,  A61M2005/14252 ,  A61M2005/14506 ,  A61M2230/201 ,  F04B9/02 ,  F04C2270/041

Abstract: A fluid delivery device comprising a fluid reservoir; a transcutaneous access tool fluidly coupled to the fluid reservoir, the transcutaneous access tool including a needle or a trocar; and a transcutaneous access tool insertion mechanism for deploying the transcutaneous access tool, wherein the insertion mechanism is configured to insert and retract the needle/trocar in a single, uninterrupted motion.

Abstract translation: 一种流体输送装置，包括流体储存器; 经皮通道工具，其流体地联接到所述流体储存器，所述经皮通路工具包括针或套管针; 以及用于展开所述经皮进入工具的经皮通道工具插入机构，其中所述插入机构构造成以单一的不间断运动来插入和缩回针/套管针。

公开(公告)号：US12300375B2

公开(公告)日：2025-05-13

申请号：US18151582

申请日：2023-01-09

Applicant: INSULET CORPORATION

Inventor： David Nazzaro ,  Steven Cardinali ,  Nicholas Conte ,  Daniel Allis ,  Jason O'Connor ,  Joon Bok Lee ,  Ashutosh Zade ,  Timothy Henning ,  Thomas Metzmaker ,  Ian McLaughlin

IPC: G16H20/60 ,  G16H20/17

Abstract: Disclosed are examples of a device, a system, methods and computer-readable medium products operable to implement functionality to determine and respond to a purpose of a meal. An algorithm or application may receive data that may include data related to a meal purpose from data sources and determine whether any of the data received from the plurality of data sources was received from a direct data source or an indirect data source. The data may be evaluated to determine a purpose of the meal. Based on the results of the evaluation, instructions may be generated to provide an appropriate response based on the determined purpose of the meal. The generated instructions to provide the appropriate response based on the determined purpose of the meal may be output.

公开(公告)号：US11746765B2

公开(公告)日：2023-09-05

申请号：US17667135

申请日：2022-02-08

Applicant: Insulet Corporation

Inventor： Daniel Allis ,  Ian McLaughlin ,  Kenneth Phillips

IPC: F04B19/00 ,  F04B1/02 ,  F04B53/10 ,  F04B1/047 ,  F04B1/0452 ,  F04B7/00 ,  F04B9/06 ,  F04B19/22 ,  F04B23/02

CPC classification number: F04B19/006 ,  F04B1/02 ,  F04B1/047 ,  F04B1/0452 ,  F04B7/003 ,  F04B7/0026 ,  F04B7/0049 ,  F04B7/0053 ,  F04B7/0096 ,  F04B9/06 ,  F04B19/22 ,  F04B23/02 ,  F04B53/109

Abstract: A low-force, non-displacement, micro/miniature valve and/or pump assembly is provided. A tube component having a first side port coupled to an inlet portion and a second side port coupled to an outlet portion can be selectively moved to alternatively couple the side ports to a first or second piston pump chamber. First and second pistons can be actuated after positioning the tube component to either draw in fluid or push out fluid from either the first or second piston pump chambers during each actuation of the pistons. The fluid can be drawn in from a reservoir and can be expelled to a patient for providing a dose of the fluid to the patient.

公开(公告)号：US11660389B2

公开(公告)日：2023-05-30

申请号：US16514621

申请日：2019-07-17

Applicant: Insulet Corporation

Inventor： Jeff Barnes ,  Jackie Mac ,  Ian McLaughlin ,  David Nazzaro ,  Steven Cardinali ,  Thomas Metzmaker

IPC: A61M5/148 ,  A61J1/20 ,  A61M5/142

CPC classification number: A61M5/148 ,  A61J1/2024 ,  A61M5/14248 ,  A61M2205/3334 ,  A61M2205/3379

Abstract: Disclosed are examples of reservoir and reservoir systems usable with a wearable drug delivery device. An example reservoir may include a flexible component coupled to a shell component. The shell component may include drainage channels to facilitate extraction of the liquid drug from the reservoir. A reservoir system example may include an exoskeleton configured around a flexible reservoir to guide the expansion and collapse of the flexible reservoir. Alternatively, one or more rigid panels may be coupled to corresponding flat surfaces of the flexible reservoir to guide the expansion and collapse of the flexible reservoir. A further reservoir example may include a flexible thin film reservoir having peel-able restraints configured to seal off corresponding sections of the reservoir, sequentially break, enabling the liquid drug to sequentially fill corresponding sections in a controlled and predicable manner. A wearable drug delivery device example suitable for utilizing the described examples is provided.

公开(公告)号：US11565039B2

公开(公告)日：2023-01-31

申请号：US16599729

申请日：2019-10-11

Applicant: INSULET CORPORATION

Inventor： Jason O'Connor ,  Joon Bok Lee ,  Ian McLaughlin ,  John D'Arco

IPC: A61M5/158 ,  A61M5/142 ,  A61M31/00 ,  A61B5/145 ,  A61B5/00

Abstract: A drug delivery device may include an Inertial Measurement Unit (IMU) is provided. The IMU may include an accelerometer, a magnetometer, or a gyroscope. Motion parameters may be detected when the drug delivery device is shipped, being prepared for activation for use, or during use. The IMU may provide data indicative of a rapid deceleration, such as when a package containing the drug delivery device is dropped, or some other physical event experienced by the drug delivery device. The drug delivery device may also include internal or external pressure sensors or a blood glucose sensor that may coordinate with the IMU to provide additional feedback regarding the status of the device or user. A controller of the drug delivery device may generate a response depending on the particular parameters being monitored or may change device operational parameters as a result of detected system events.

公开(公告)号：US11383038B2

公开(公告)日：2022-07-12

申请号：US16140186

申请日：2018-09-24

Applicant: Insulet Corporation

Inventor： David Nazzaro ,  Ian McLaughlin ,  Maureen McCaffrey ,  Simon Kozin ,  Jackie Mac

IPC: A61M5/20 ,  A61M5/315 ,  A61M5/158 ,  A61M5/145 ,  A61M5/142 ,  A61M5/00 ,  A61M5/28 ,  A61M5/24

Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can be controlled to provide the liquid drug to the patient in a single dose or over multiple doses.